Published in Am J Hematol on September 01, 1998
Sickle Cell Disease in the Post Genomic Era: A Monogenic Disease with a Polygenic Phenotype. Genomics Insights (2009) 0.96
Role of the hemostatic system on sickle cell disease pathophysiology and potential therapeutics. Hematol Oncol Clin North Am (2014) 0.84
Sickle cell disease and venous thromboembolism. Mediterr J Hematol Infect Dis (2011) 0.81
Prevalence of Factor V Leiden-G1691A and MTHFR-C677T Thrombosis Gene Modifier in Iron Deficiency Anemia: A Pathophysiological Effect in Indian Isolates. Indian J Clin Biochem (2016) 0.75
A 19-year-old man with sickle cell disease presenting with spinal infarction: a case report. J Med Case Rep (2013) 0.75
The genome sequence of the plant pathogen Xylella fastidiosa. The Xylella fastidiosa Consortium of the Organization for Nucleotide Sequencing and Analysis. Nature (2000) 10.03
The contribution of 700,000 ORF sequence tags to the definition of the human transcriptome. Proc Natl Acad Sci U S A (2001) 2.71
Shotgun sequencing of the human transcriptome with ORF expressed sequence tags. Proc Natl Acad Sci U S A (2000) 2.21
Muscle-directed gene transfer and transient immune suppression result in sustained partial correction of canine hemophilia B caused by a null mutation. Mol Ther (2001) 1.93
Identification of human chromosome 22 transcribed sequences with ORF expressed sequence tags. Proc Natl Acad Sci U S A (2000) 1.84
Geographic distribution of the 20210 G to A prothrombin variant. Thromb Haemost (1998) 1.71
Cytomegalovirus infection as cause of severe thrombocytopenia in a nonimmunosuppressed patient. Acta Haematol (1997) 1.63
Role of vector in activation of T cell subsets in immune responses against the secreted transgene product factor IX. Mol Ther (2000) 1.55
Risk and prevention of anti-factor IX formation in AAV-mediated gene transfer in the context of a large deletion of F9. Mol Ther (2001) 1.54
Molecular therapy in the microRNA era. Pharmacogenomics J (2006) 1.52
Factor V Leiden is not common in children with portal vein thrombosis. Thromb Haemost (1997) 1.43
Point mutation in the beta-spectrin gene associated with alpha I/74 hereditary elliptocytosis. Implications for the mechanism of spectrin dimer self-association. J Clin Invest (1990) 1.41
Altered levels of cytokines and inflammatory mediators in plasma and leukocytes of sickle cell anemia patients and effects of hydroxyurea therapy. J Leukoc Biol (2008) 1.40
Hb Rio Claro [beta34(B16)Val-->Met]: a novel electrophoretically silent variant found in association with Hb Hasharon [alpha47(CE5)Asp-->His] and alpha-thalassemia-2(-alpha3.7). Hemoglobin (1999) 1.40
Effect of alpha-thalassemia and beta-globin gene cluster haplotypes on the hematological and clinical features of sickle-cell anemia in Brazil. Am J Hematol (1996) 1.36
Optical tweezers for measuring red blood cell elasticity: application to the study of drug response in sickle cell disease. Eur J Haematol (2003) 1.24
Sickle cell disease in a Brazilian population from Sao Paulo: a study of the beta s haplotypes. Hum Hered (1995) 1.20
Beta spectrin in human skeletal muscle. Tissue-specific differential processing of 3' beta spectrin pre-mRNA generates a beta spectrin isoform with a unique carboxyl terminus. J Biol Chem (1990) 1.20
High prevalence of alpha-thalassemia in a black population of Brazil. Hemoglobin (1991) 1.18
Factor V Leiden improves in vivo hemostasis in murine hemophilia models. J Thromb Haemost (2005) 1.17
Duplication of 10 nucleotides in the erythroid band 3 (AE1) gene in a kindred with hereditary spherocytosis and band 3 protein deficiency (band 3PRAGUE). J Clin Invest (1994) 1.05
Increasing seroprevalence of human herpesvirus 8 (HHV-8) with age confirms HHV-8 endemicity in Amazon Amerindians from Brazil. J Gen Virol (2005) 1.04
A viable mouse model of factor X deficiency provides evidence for maternal transfer of factor X. J Thromb Haemost (2007) 1.04
Hereditary hemoglobin disorders in a Brazilian population. Hum Hered (1983) 1.04
miR-433 is aberrantly expressed in myeloproliferative neoplasms and suppresses hematopoietic cell growth and differentiation. Leukemia (2012) 1.01
The mutation Ala677-->Val in the methylene tetrahydrofolate reductase gene: a risk factor for arterial disease and venous thrombosis. Thromb Haemost (1997) 1.00
Hereditary haemoglobin disorders in Brazil. Trans R Soc Trop Med Hyg (1985) 0.99
The release of nitric oxide and superoxide anion by neutrophils and mononuclear cells from patients with sickle cell anaemia. Br J Haematol (1996) 0.98
alpha-globin genes: thalassemic and structural alterations in a Brazilian population. Braz J Med Biol Res (2000) 0.98
Absence of circulating factor IX antigen in hemophilia B dogs of the UNC-Chapel Hill colony. Thromb Haemost (2000) 0.98
Intravenous administration of an E1/E3-deleted adenoviral vector induces tolerance to factor IX in C57BL/6 mice. Gene Ther (2001) 0.97
The impact of microRNAs and alternative splicing in pharmacogenomics. Pharmacogenomics J (2009) 0.96
A novel mobile element inserted in the alpha spectrin gene: spectrin dayton. A truncated alpha spectrin associated with hereditary elliptocytosis. J Clin Invest (1994) 0.95
High prevalence of alpha-thalassemia among individuals with microcytosis and hypochromia without anemia. Braz J Med Biol Res (2001) 0.95
DNA array analysis for red blood cell antigens facilitates the transfusion support with antigen-matched blood in patients with sickle cell disease. Vox Sang (2009) 0.95
A novel FY allele in Brazilians. Vox Sang (2004) 0.95
Enalapril reduces the albuminuria of patients with sickle cell disease. Am J Med (1995) 0.95
Frequencies of platelet-specific alloantigen systems 1-5 in three distinct ethnic groups in Brazil. Eur J Immunogenet (1999) 0.95
Prevention of spontaneous bleeding in dogs with haemophilia A and haemophilia B. Haemophilia (2010) 0.94
Mechanical properties of stored red blood cells using optical tweezers. Blood (1998) 0.93
Association of Hb Santa Ana [alpha 2 beta (2)88(F4)Leu- > Pro] and Hb Porto Alegre [alpha 2 beta (2)9(A6)Ser- > Cys] in a Brazilian female. Hemoglobin (1994) 0.93
Inherited thrombophilia as a risk factor for the development of ischemic stroke in young adults. Thromb Haemost (2000) 0.93
Lutzomyia longipalpis: pH in the gut, digestive glycosidases, and some speculations upon Leishmania development. Exp Parasitol (1998) 0.92
Prevalence of homozygosity for the deleted alleles of glutathione S-transferase mu (GSTM1) and theta (GSTT1) among distinct ethnic groups from Brazil: relevance to environmental carcinogenesis? Clin Genet (1998) 0.92
Molecular studies reveal that A134T, G156A and G1333A SNPs in the CD177 gene are associated with atypical expression of human neutrophil antigen-2. Vox Sang (2009) 0.92
Presence of the RHD pseudogene and the hybrid RHD-CE-D(s) gene in Brazilians with the D-negative phenotype. Braz J Med Biol Res (2002) 0.91
Diagnosis of hepatitis C virus in Brazilian blood donors using a reverse transcriptase nested polymerase chain reaction: comparison with enzyme immunoassay and recombinant protein immunoblot assay. Rev Inst Med Trop Sao Paulo (2000) 0.91
Clinical and genetic risk factors for moderate hyperbilirubinemia in Brazilian newborn infants. J Perinatol (2010) 0.90
Genetic analysis of beta-thalassemia major and beta-thalassemia intermedia in Brazil. Hemoglobin (1998) 0.90
Frequencies of UDP-glucuronosyltransferase 1 (UGT1A1) gene promoter polymorphisms among distinct ethnic groups from Brazil. Am J Med Genet (2002) 0.90
An insertional frameshift mutation of the beta-spectrin gene associated with elliptocytosis in spectrin nice (beta 220/216). Blood (1991) 0.90
Prevalence of the mutation C677 --> T in the methylene tetrahydrofolate reductase gene among distinct ethnic groups in Brazil. Am J Med Genet (1998) 0.90
p53, Mdm2, and c-Myc overexpression is associated with a poor prognosis in aggressive non-Hodgkin's lymphomas. Am J Hematol (2001) 0.90
Hydroxyurea is associated with reductions in hypercoagulability markers in sickle cell anemia. J Thromb Haemost (2012) 0.90
Prevalence of the prothrombin gene variant (nt20210A) in venous thrombosis and arterial disease. Thromb Haemost (1997) 0.89
N-ras gene point mutations in Brazilian acute myelogenous leukemia patients correlate with a poor prognosis. Leuk Lymphoma (1997) 0.89
Discrepancy between pit counting and spleen function tests in nutritional anemias and hemoglobinopathy C. Nouv Rev Fr Hematol (1986) 0.89
Mutation analysis of the HFE gene in Brazilian populations. Blood Cells Mol Dis (2000) 0.89
UDP-glucuronosyltransferase 1 gene promoter polymorphism is associated with increased serum bilirubin levels and cholecystectomy in patients with sickle cell anemia. Clin Genet (2003) 0.89
Clinical, hematological and genetic features of sickle-cell anemia and sickle cell-beta thalassemia in a Brazilian population. Clin Genet (1980) 0.88
Third-trimester erythrocytapheresis in pregnant patients with sickle cell disease. Int J Gynaecol Obstet (2006) 0.88
Increased risk for acute myeloid leukaemia in individuals with glutathione S-transferase mu 1 (GSTM1) and theta 1 (GSTT1) gene defects. Eur J Haematol (2001) 0.88
Microalbuminuria in sickle cell disease. Braz J Med Biol Res (1990) 0.88
Factor V Leiden (FVQ 506) is common in a Brazilian population. Am J Hematol (1995) 0.88
Thalassemia intermedia as a result of heterozygosis for beta 0 -thalassemia and alpha alpha alpha anti-3,7 genotype in a Brazilian patient. Braz J Med Biol Res (2003) 0.87
Improved muscle-derived expression of human coagulation factor IX from a skeletal actin/CMV hybrid enhancer/promoter. Blood (2000) 0.87
Nested-PCR using MPB64 fragment improves the diagnosis of pleural and meningeal tuberculosis. Rev Soc Bras Med Trop (2000) 0.86
Vitamin E supplementation reduces oxidative stress in beta thalassaemia intermedia. Acta Haematol (2009) 0.86
[Brazilian guidelines on platelet antiaggregants and anticoagulants in cardiology]. Arq Bras Cardiol (2013) 0.86
Increased tyrosine phosphorylation of band 3 in hemoglobinopathies. Am J Hematol (1998) 0.86
Characterization of Aspergillus flavus strains from Brazilian Brazil nuts and cashew by RAPD and ribosomal DNA analysis. Lett Appl Microbiol (2008) 0.85
Elastic properties of stored red blood cells from sickle trait donor units. Vox Sang (2003) 0.85