Published in Microbiol Mol Biol Rev on September 01, 1998
Intracellular growth of Legionella pneumophila in Dictyostelium discoideum, a system for genetic analysis of host-pathogen interactions. Infect Immun (2000) 2.46
Genome-wide expression analyses of gene regulation during early development of Dictyostelium discoideum. Eukaryot Cell (2003) 1.57
RasC is required for optimal activation of adenylyl cyclase and Akt/PKB during aggregation. EMBO J (2001) 1.44
Regulated protein degradation controls PKA function and cell-type differentiation in Dictyostelium. Genes Dev (2001) 1.24
Cell signaling during development of Dictyostelium. Dev Biol (2014) 1.20
The internal phosphodiesterase RegA is essential for the suppression of lateral pseudopods during Dictyostelium chemotaxis. Mol Biol Cell (2000) 1.07
Role of protein kinase A in Trypanosoma cruzi. Infect Immun (2008) 1.00
Osmotic stress response in Dictyostelium is mediated by cAMP. EMBO J (2000) 0.98
Outside-in signaling of cellulose synthesis by a spore coat protein in Dictyostelium. Eukaryot Cell (2002) 0.92
Constitutively active protein kinase A disrupts motility and chemotaxis in Dictyostelium discoideum. Eukaryot Cell (2003) 0.91
Genetic interactions of the E3 ubiquitin ligase component FbxA with cyclic AMP metabolism and a histidine kinase signaling pathway during Dictyostelium discoideum development. Eukaryot Cell (2003) 0.90
A Phg2-Adrm1 pathway participates in the nutrient-controlled developmental response in Dictyostelium. Mol Biol Cell (2006) 0.88
CulB, a putative ubiquitin ligase subunit, regulates prestalk cell differentiation and morphogenesis in Dictyostelium spp. Eukaryot Cell (2002) 0.88
Role for YakA, cAMP, and protein kinase A in regulation of stress responses of Dictyostelium discoideum cells. Mol Biol Cell (2002) 0.88
Genetic control of morphogenesis in Dictyostelium. Dev Biol (2015) 0.84
BzpF is a CREB-like transcription factor that regulates spore maturation and stability in Dictyostelium. Dev Biol (2011) 0.83
New components of the Dictyostelium PKA pathway revealed by Bayesian analysis of expression data. BMC Bioinformatics (2010) 0.81
Partial genetic suppression of a loss-of-function mutant of the neuronal ceroid lipofuscinosis-associated protease TPP1 in Dictyostelium discoideum. Dis Model Mech (2014) 0.79
KeaA, a Dictyostelium Kelch-domain protein that regulates the response to stress and development. BMC Dev Biol (2010) 0.76
The Dictyostelium MAPK ERK1 is phosphorylated in a secondary response to early developmental signaling. Cell Signal (2014) 0.76
Loss of cAMP-specific phosphodiesterase rescues spore development in G protein mutant in dictyostelium. Cell Signal (2014) 0.75
Targets downstream of Cdk8 in Dictyostelium development. BMC Dev Biol (2011) 0.75
The acrasin activity of adenosine-3',5'-cyclic phosphate. Proc Natl Acad Sci U S A (1967) 5.29
cAMP-dependent protein kinase: framework for a diverse family of regulatory enzymes. Annu Rev Biochem (1990) 5.02
Phosphorylation of bacterial response regulator proteins by low molecular weight phospho-donors. Proc Natl Acad Sci U S A (1992) 4.88
Genetic demonstration of a role for PKA in the late phase of LTP and in hippocampus-based long-term memory. Cell (1997) 4.83
cul-1 is required for cell cycle exit in C. elegans and identifies a novel gene family. Cell (1996) 4.11
Cdc53 targets phosphorylated G1 cyclins for degradation by the ubiquitin proteolytic pathway. Cell (1996) 4.06
dunce, a mutant of Drosophila deficient in learning. Proc Natl Acad Sci U S A (1976) 3.74
RcsB and RcsC: a two-component regulator of capsule synthesis in Escherichia coli. J Bacteriol (1990) 3.62
Adenosine 3',5'-monophosphate waves in Dictyostelium discoideum: a demonstration by isotope dilution--fluorography. Science (1981) 3.43
Protein histidine kinases and signal transduction in prokaryotes and eukaryotes. Trends Genet (1994) 2.85
The Drosophila learning and memory gene rutabaga encodes a Ca2+/Calmodulin-responsive adenylyl cyclase. Cell (1992) 2.80
Signal propagation during aggregation in the slime mould Dictyostelium discoideum. J Gen Microbiol (1974) 2.68
Structurally distinct and stage-specific adenylyl cyclase genes play different roles in Dictyostelium development. Cell (1992) 2.60
Loss of calcium/calmodulin responsiveness in adenylate cyclase of rutabaga, a Drosophila learning mutant. Cell (1984) 2.60
A chemoattractant receptor controls development in Dictyostelium discoideum. Science (1988) 2.54
Glycogen synthase kinase 3 regulates cell fate in Dictyostelium. Cell (1995) 2.49
Studies on the properties and mode of action of the purified regulatory subunit of bovine heart adenosine 3':5'-monophosphate-dependent protein kinase. J Biol Chem (1978) 2.32
Molecular genetics of signal transduction in Dictyostelium. Annu Rev Biochem (1996) 2.28
Function of protein kinase A in hedgehog signal transduction and Drosophila imaginal disc development. Cell (1995) 2.15
Developmental signal transduction pathways uncovered by genetic suppressors. Proc Natl Acad Sci U S A (1996) 2.13
Dictyostelium development in the absence of cAMP. Science (1997) 2.01
CRAC, a cytosolic protein containing a pleckstrin homology domain, is required for receptor and G protein-mediated activation of adenylyl cyclase in Dictyostelium. J Cell Biol (1994) 1.96
Protein kinase A is a common negative regulator of Hedgehog signaling in the vertebrate embryo. Genes Dev (1996) 1.92
Preferential expression in mushroom bodies of the catalytic subunit of protein kinase A and its role in learning and memory. Neuron (1993) 1.88
Origins of the prestalk-prespore pattern in Dictyostelium development. Cell (1989) 1.78
Cyclic-AMP-controlled oscillations in suspended Dictyostelium cells: their relation to morphogenetic cell interactions. Proc Natl Acad Sci U S A (1974) 1.77
A MAP kinase necessary for receptor-mediated activation of adenylyl cyclase in Dictyostelium. J Cell Biol (1995) 1.77
LagC is required for cell-cell interactions that are essential for cell-type differentiation in Dictyostelium. Genes Dev (1994) 1.76
A G-protein beta-subunit is essential for Dictyostelium development. Genes Dev (1993) 1.74
G protein-linked signaling pathways control the developmental program of Dictyostelium. Neuron (1994) 1.74
Molecular genetic analysis of two G alpha protein subunits in Dictyostelium. J Biol Chem (1991) 1.72
A cAMP-phosphodiesterase controls PKA-dependent differentiation. Development (1998) 1.65
Integration of signaling information in controlling cell-fate decisions in Dictyostelium. Genes Dev (1995) 1.65
A developmentally regulated, putative serine/threonine protein kinase is essential for development in Dictyostelium. Mech Dev (1991) 1.61
Density-dependent induction of discoidin-I synthesis in exponentially growing cells of Dictyostelium discoideum. Differentiation (1987) 1.61
A mutation affecting both rate and pattern of morphogenesis in Dictyostelium discoideum. Dev Biol (1963) 1.61
A mechanism for exact sensory adaptation based on receptor modification. J Theor Biol (1986) 1.54
A two-component histidine kinase gene that functions in Dictyostelium development. EMBO J (1996) 1.50
Signal transduction pathways leading to spore differentiation in Dictyostelium discoideum. Dev Biol (1998) 1.50
Cloning and characterization of the G-box binding factor, an essential component of the developmental switch between early and late development in Dictyostelium. Genes Dev (1994) 1.49
Cloning and characterization of mammalian homologs of the Drosophila dunce+ gene. Proc Natl Acad Sci U S A (1989) 1.48
Histidine kinases in signal transduction pathways of eukaryotes. J Cell Sci (1997) 1.47
A multidrug resistance transporter/serine protease gene is required for prestalk specialization in Dictyostelium. Genes Dev (1995) 1.47
Genetic investigation of cAMP-dependent protein kinase function in Drosophila development. Genes Dev (1993) 1.38
Mutation of protein kinase A causes heterochronic development of Dictyostelium. Nature (1992) 1.36
Signal transduction pathways controlling multicellular development in Dictyostelium. Trends Genet (1992) 1.35
Seven helix chemoattractant receptors transiently stimulate mitogen-activated protein kinase in Dictyostelium. Role of heterotrimeric G proteins. J Biol Chem (1996) 1.34
A new class of rapidly developing mutants in Dictyostelium discoideum: implications for cyclic AMP metabolism and cell differentiation. Dev Biol (1983) 1.34
Culmination in Dictyostelium is regulated by the cAMP-dependent protein kinase. Cell (1992) 1.33
Phenotypic changes induced by a mutated ras gene during the development of Dictyostelium transformants. Nature (1986) 1.33
Two cAMP receptors activate common signaling pathways in Dictyostelium. Mol Biol Cell (1994) 1.31
Pattern formation in Dictyostelium via the dynamics of cooperative biological entities. Phys Rev E Stat Phys Plasmas Fluids Relat Interdiscip Topics (1993) 1.30
Overexpression of Dd PK2 protein kinase causes rapid development and affects the intracellular cAMP pathway of Dictyostelium discoideum. Development (1992) 1.30
PSF and CMF, autocrine factors that regulate gene expression during growth and early development of Dictyostelium. Experientia (1995) 1.30
Isolation and characterization of Drosophila cAMP-dependent protein kinase genes. Genes Dev (1988) 1.30
Signal emission and signal propagation during early aggregation in Dictyostelium discoideum. J Cell Sci (1976) 1.29
CAR2, a prestalk cAMP receptor required for normal tip formation and late development of Dictyostelium discoideum. Genes Dev (1993) 1.27
Progression of an inductive signal activates sporulation in Dictyostelium discoideum. Development (1994) 1.27
Multiple cyclic AMP receptors are linked to adenylyl cyclase in Dictyostelium. Mol Biol Cell (1992) 1.27
Positive genetic feedback governs cAMP spiral wave formation in Dictyostelium. Proc Natl Acad Sci U S A (1996) 1.27
Phosphorylation of chemoattractant receptors is not essential for chemotaxis or termination of G-protein-mediated responses. J Biol Chem (1997) 1.27
cAMP-dependent protein kinase and hedgehog act antagonistically in regulating decapentaplegic transcription in Drosophila imaginal discs. Cell (1995) 1.26
cAMP-dependent protein kinase and the disruption of learning in transgenic flies. Neuron (1991) 1.25
Expression of a cAMP receptor gene of Dictyostelium and evidence for a multigene family. Genes Dev (1991) 1.23
The Dictyostelium MAP kinase ERK2 regulates multiple, independent developmental pathways. Genes Dev (1996) 1.22
Adenylyl cyclase G, an osmosensor controlling germination of Dictyostelium spores. J Biol Chem (1996) 1.21
Genetic networks that regulate development in Dictyostelium cells. Microbiol Rev (1996) 1.20
Oscillations of cyclic nucleotide concentrations in relation to the excitability of Dictyostelium cells. J Exp Biol (1979) 1.19
Multiple roles for cAMP-dependent protein kinase during Dictyostelium development. Dev Biol (1992) 1.17
Role of cAMP-dependent protein kinase in controlling aggregation and postaggregative development in Dictyostelium. Dev Biol (1997) 1.16
cAMP-dependent protein kinase differentially regulates prestalk and prespore differentiation during Dictyostelium development. Development (1993) 1.14
DdPK3, which plays essential roles during Dictyostelium development, encodes the catalytic subunit of cAMP-dependent protein kinase. Proc Natl Acad Sci U S A (1992) 1.13
Identification and targeted gene disruption of cAR3, a cAMP receptor subtype expressed during multicellular stages of Dictyostelium development. Genes Dev (1993) 1.12
Mitochondrial DNA replication but no nuclear DNA replication during development of Dictyostelium. Proc Natl Acad Sci U S A (1995) 1.11
A cAMP-dependent protein kinase is present in differentiating Dictyostelium discoideum cells. EMBO J (1982) 1.08
Induction of terminal differentiation of Dictyostelium by cAMP-dependent protein kinase and opposing effects of intracellulr and extracellular cAMP on stalk cell differentiation. Development (1993) 1.08
Induction of gene expression in Dictyostelium by prestarvation factor, a factor secreted by growing cells. Dev Genet (1991) 1.08
Spore coat proteins of Dictyostelium discoideum are packaged in prespore vesicles. Dev Biol (1983) 1.07
Analysis of the prestarvation response in growing cells of Dictyostelium discoideum. Dev Genet (1988) 1.06
Disruption of the sporulation-specific gene spiA in Dictyostelium discoideum leads to spore instability. Genes Dev (1992) 1.06
The regulation of Dictyostelium development by transmembrane signalling. J Eukaryot Microbiol (1996) 1.05
Enhancer regions responsible for temporal and cell-type-specific expression of a spore coat gene in Dictyostelium. Dev Biol (1993) 1.04
Overproduction of the regulatory subunit of the cAMP-dependent protein kinase blocks the differentiation of Dictyostelium discoideum. EMBO J (1989) 1.03
Initial cell type divergence in Dictyostelium is independent of DIF-1. Dev Biol (1996) 1.03
A cytosolic cyclic AMP-dependent protein kinase in Dictyostelium discoideum. II. Developmental regulation. J Biol Chem (1984) 1.03
The hybrid histidine kinase dhkB regulates spore germination in Dictyostelium discoideum. Dev Biol (1998) 1.03
Agonist-induced loss of ligand binding is correlated with phosphorylation of cAR1, a G protein-coupled chemoattractant receptor from Dictyostelium. J Biol Chem (1995) 1.01
Expression of cAMP-dependent protein kinase in prespore cells is sufficient to induce spore cell differentiation in Dictyostelium. Proc Natl Acad Sci U S A (1994) 1.00
Serpentine cAMP receptors may act through a G protein-independent pathway to induce postaggregative development in Dictyostelium. Cell (1995) 1.00
The Dictyostelium mitogen-activated protein kinase ERK2 is regulated by Ras and cAMP-dependent protein kinase (PKA) and mediates PKA function. J Biol Chem (1997) 0.99
A prespore gene, Dd31, expressed during culmination of Dictyostelium discoideum. Dev Biol (1991) 0.99
Localization of ligand-induced phosphorylation sites to serine clusters in the C-terminal domain of the Dictyostelium cAMP receptor, cAR1. J Biol Chem (1994) 0.96
Coordinate regulation of the spore coat genes in Dictyostelium discoideum. Dev Genet (1991) 0.95
Occupancy of the Dictyostelium cAMP receptor, cAR1, induces a reduction in affinity which depends upon COOH-terminal serine residues. J Biol Chem (1995) 0.94
A new spore differentiation factor (SDF) secreted by Dictyostelium cells is phosphorylated by the cAMP dependent protein kinase. Differentiation (1997) 0.93
Sexual hyperactivity and reduced longevity of dunce females of Drosophila melanogaster. Genetics (1987) 0.91
Dual role of cAMP and involvement of both G-proteins and ras in regulation of ERK2 in Dictyostelium discoideum. EMBO J (1996) 0.91
The cAMP receptor subtype cAR2 is restricted to a subset of prestalk cells during Dictyostelium development and displays unexpected DIF-1 responsiveness. Dev Biol (1996) 0.90
The cAMP receptor CAR4 regulates axial patterning and cellular differentiation during late development of Dictyostelium. Genes Dev (1994) 0.89
The regulatory subunit of cAMP-dependent protein kinase from Dictyostelium discoideum: cellular localization and developmental regulation analyzed by immunoblotting. Cell Differ (1985) 0.89