Published in Cancer on September 15, 1998
Metalloproteinases: role in breast carcinogenesis, invasion and metastasis. Breast Cancer Res (2000) 3.41
Study of matrix metalloproteinases and their inhibitors in breast cancer. Br J Cancer (2007) 1.63
Expression of matrix metalloproteinases (MMPs) in primary human breast cancer and breast cancer cell lines: New findings and review of the literature. BMC Cancer (2009) 1.58
Antimetastatic Potentials of Dioscorea nipponica on Melanoma In Vitro and In Vivo. Evid Based Complement Alternat Med (2011) 1.56
Matrix metalloproteinase-2 (MMP-2) is associated with survival in breast carcinoma. Br J Cancer (2003) 1.45
Function of alpha3beta1-tetraspanin protein complexes in tumor cell invasion. Evidence for the role of the complexes in production of matrix metalloproteinase 2 (MMP-2). J Cell Biol (1999) 1.42
CD10 expression in urothelial carcinoma of the bladder. Diagn Pathol (2009) 1.09
Membrane type-1 matrix metalloproteinase stimulates tumour cell-induced platelet aggregation: role of receptor glycoproteins. Br J Pharmacol (2003) 1.08
Regulation of angiogenesis and invasion by human Pituitary tumor transforming gene (PTTG) through increased expression and secretion of matrix metalloproteinase-2 (MMP-2). Mol Cancer (2006) 1.07
Expression of MMP-2 correlates with increased angiogenesis in CNS metastasis of lung carcinoma. Int J Clin Exp Pathol (2010) 1.04
Association of 12 serum biochemical markers of angiogenesis, tumour invasion and bone turnover with bone metastases from breast cancer: a crossectional and longitudinal evaluation. Br J Cancer (2006) 0.96
Expression of MT-1 MMP, MMP2, MMP9 and TIMP2 mRNAs in ductal carcinoma in situ and invasive ductal carcinoma of the breast. Yonsei Med J (2006) 0.94
Bombesin antagonists inhibit proangiogenic factors in human experimental breast cancers. Br J Cancer (2004) 0.92
Tetrathiomolybdate inhibits head and neck cancer metastasis by decreasing tumor cell motility, invasiveness and by promoting tumor cell anoikis. Mol Cancer (2010) 0.92
Clinicopathologic and prognostic significance of matrix metalloproteinases in rectal cancer. Int J Colorectal Dis (2006) 0.89
Expression of MMP-2,TIMP-2 protein and the ratio of MMP-2/TIMP-2 in gallbladder carcinoma and their significance. World J Gastroenterol (2002) 0.88
Lymph node status as a guide to selection of available prognostic markers in breast cancer: the clinical practice of the future? Diagn Pathol (2006) 0.85
Clinical significance of matrix metalloproteinase-9 expression in esophageal squamous cell carcinoma. World J Gastroenterol (2005) 0.84
Cellular protein and mRNA expression patterns of matrix metalloproteinases-2, -3 and -9 in human breast cancer: correlation with tumour growth. J Mol Histol (2004) 0.84
The impact of matrix metalloproteinase 2 on prognosis and clinicopathology of breast cancer patients: a systematic meta-analysis. PLoS One (2015) 0.81
Plasma gelatinase levels in patients with primary breast cancer in relation to axillary lymph node status, Her2/neu expression and other clinicopathological variables. Clin Exp Metastasis (2005) 0.79
Xq25 and Xq26 identify the common minimal deletion region in malignant gastroenteropancreatic endocrine carcinomas. Virchows Arch (2005) 0.79
O-phenyl carbamate and phenyl urea thiiranes as selective matrix metalloproteinase-2 inhibitors that cross the blood-brain barrier. J Med Chem (2013) 0.78
Matrix metalloproteinases 2 and 9 immunoexpression in prostate carcinoma at the positive margin of radical prostatectomy specimens. Patholog Res Int (2014) 0.76
Clinical significance of aromatase protein expression in axillary node negative breast cancer. J Cancer Res Clin Oncol (2007) 0.76
Plasma levels of matrix metalloproteinases 2 and 9 correlate with histological grade in breast cancer patients. Oncol Lett (2012) 0.76
Plasma matrix metalloproteinase 2 levels and breast cancer risk. Cancer Epidemiol (2015) 0.75
Catalyser-21(TM), a mineral water derived from leaf soil, inhibits tumor cell invasion and angiogenesis. Cytotechnology (2007) 0.75
Expression and survival significance of B-cell-specific Moloney murine leukemia virus integration site 1 and matrix metalloproteinase-9 in non-small-cell lung cancer. Oncol Lett (2016) 0.75
Expression and prognostic impact of matrix metalloproteinase-2 (MMP-2) in astrocytomas. PLoS One (2017) 0.75
Inherent aggressive character of invasive and non-invasive cells dictates the in vitro migration pattern of multicellular spheroid. Sci Rep (2017) 0.75
Proteolytic degradation of extracellular matrix in tumor invasion. Biochim Biophys Acta (1987) 2.06
Identification of a distinct type IV collagen alpha chain with restricted kidney distribution and assignment of its gene to the locus of X chromosome-linked Alport syndrome. Proc Natl Acad Sci U S A (1990) 2.04
Matrix metalloproteinase-9 is elevated in serum of alcohol abusers. Eur J Clin Invest (2002) 1.55
A high number of tumor-infiltrating lymphocytes are associated with a small tumor size, low tumor stage, and a favorable prognosis in operated small cell lung carcinoma. Clin Cancer Res (2000) 1.53
NIH/3T3 cells transfected with human tumor DNA containing activated ras oncogenes express the metastatic phenotype in nude mice. Mol Cell Biol (1985) 1.48
Serum matrix metalloproteinases -2, -9 and tissue inhibitors of metalloproteinases -1, -2 in lung cancer--TIMP-1 as a prognostic marker. Anticancer Res (2000) 1.45
Matrix metalloproteinase-2 (MMP-2) is associated with survival in breast carcinoma. Br J Cancer (2003) 1.45
Type IV collagenases in invasive tumors. Breast Cancer Res Treat (1993) 1.43
Regarding "Detection of active cytomegalovirus infection in inflammatory aortic aneurysms with RNA polymerase chain reaction". J Vasc Surg (1998) 1.39
Omission of histologic grading from clinical decision making may result in overuse of adjuvant therapies in breast cancer: results from a nationwide study. J Clin Oncol (2001) 1.33
Secretion of basement membrane collagen degrading enzyme and plasminogen activator by transformed cells--role in metastasis. Int J Cancer (1982) 1.31
Histopathological evaluation of apoptosis in cancer. Am J Pathol (1998) 1.31
Inducible nitric oxide synthase expression, apoptosis, and angiogenesis in in situ and invasive breast carcinomas. Clin Cancer Res (2000) 1.22
Enhanced expression of tissue inhibitor of metalloproteinase-2 (TIMP-2) in the stroma of breast carcinomas correlates with tumor recurrence. Int J Cancer (1994) 1.22
Enhanced apoptosis predicts shortened survival in non-small cell lung carcinoma. Cancer Res (1995) 1.19
Expression of collagenase IV (basement membrane collagenase) activity in murine tumor cell hybrids that differ in metastatic potential. J Natl Cancer Inst (1985) 1.14
Simultaneous expression of 70 kilodalton type IV collagenase and type IV collagen alpha 1 (IV) chain genes by cells of early human placenta and gestational endometrium. Lab Invest (1992) 1.14
Apoptotic activity is increased in the newly formed fibromyxoid connective tissue in bronchiolitis obliterans organizing pneumonia. Lung (1999) 1.14
Macrophages contain 92-kd gelatinase (MMP-9) at the site of degenerated internal elastic lamina in temporal arteritis. Am J Pathol (1996) 1.13
Matrix metalloproteinase-2 (72 kD type IV collagenase) expression occurs in the early stage of human melanocytic tumour progression and may have prognostic value. J Pathol (1996) 1.13
Molecular cloning of chick lysyl hydroxylase. Little homology in primary structure to the two types of subunit of prolyl 4-hydroxylase. J Biol Chem (1991) 1.12
Monoclonal antibodies to human prolyl 4-hydroxylase. Eur J Biochem (1984) 1.10
p53 and c-erbB-2 protein expression in adenocarcinomas and epithelial dysplasias of the gall bladder. J Pathol (1993) 1.09
Laminin increases the release of type IV collagenase from malignant cells. J Biol Chem (1986) 1.09
Prognostic significance of matrix metalloproteinase-9 (MMP-9) in epithelial ovarian cancer. Gynecol Oncol (2006) 1.09
Comparative analysis of p53 protein immunoreactivity in prostatic, lung and breast carcinomas. Virchows Arch A Pathol Anat Histopathol (1992) 1.09
Prognostic value of MMP-2 immunoreactive protein (72 kD type IV collagenase) in primary skin melanoma. J Pathol (1998) 1.08
Apoptosis during breast carcinoma progression. Clin Cancer Res (1999) 1.08
Differential expression of laminins and their integrin receptors in developing and adult human lung. Am J Respir Cell Mol Biol (1996) 1.08
Hepatocellular carcinomas with a high proliferation index and a low degree of apoptosis and necrosis are associated with a shortened survival. Br J Cancer (1996) 1.05
72 KD and 92 KD type IV collagenase, type IV collagen, and laminin mRNAs in breast cancer: a study by in situ hybridization. J Histochem Cytochem (1994) 1.05
MnSOD expression is less frequent in tumour cells of invasive breast carcinomas than in in situ carcinomas or non-neoplastic breast epithelial cells. J Pathol (2001) 1.05
Tenascin in salivary gland tumours. Virchows Arch A Pathol Anat Histopathol (1992) 1.05
Expression of 72 kilodalton type IV collagenase (gelatinase A) in benign and malignant ovarian tumors. Lab Invest (1993) 1.04
Relationship between histopathological features and the course of idiopathic pulmonary fibrosis/usual interstitial pneumonia. Thorax (2006) 1.04
Up-regulation of thioredoxin and thioredoxin reductase in human malignant pleural mesothelioma. Int J Cancer (2001) 1.04
Elevated serum levels of type I collagen degradation marker ICTP and tissue inhibitor of metalloproteinase (TIMP) 1 are associated with poor prognosis in lung cancer. Clin Cancer Res (2001) 1.02
Matrix metalloproteinase 2 (MMP-2) immunoreactive protein is associated with poor grade and survival in brain neoplasms. J Neurooncol (2000) 1.02
Apoptosis and expression of apoptosis regulating proteins bcl-2, mcl-1, bcl-X, and bax in malignant mesothelioma. Clin Cancer Res (1999) 1.02
Tumor-promoting phorbol esters and cell proliferation stimulate secretion of basement membrane (type IV) collagen-degrading metalloproteinase by human fibroblasts. J Biol Chem (1985) 1.02
Expression of the laminin gamma2 chain in different histological types of lung carcinoma. A study by immunohistochemistry and in situ hybridization. J Pathol (1999) 1.02
Expression of caspases 3, 6 and 8 is increased in parallel with apoptosis and histological aggressiveness of the breast lesion. Br J Cancer (1999) 1.02
Serum concentrations of collagen degrading enzymes and their inhibitors after downhill running. Scand J Med Sci Sports (2001) 1.01
Limited value of preoperative serum analyses of matrix metalloproteinases (MMP-2, MMP-9) and tissue inhibitors of matrix metalloproteinases (TIMP-1, TIMP-2) in colorectal cancer. Anticancer Res (2000) 1.00
Concurrent p53 expression in bronchial dysplasias and squamous cell lung carcinomas. Am J Pathol (1993) 0.99
Monoclonal antibodies to type IV collagenase recognize a protein with limited sequence homology to interstitial collagenase and stromelysin. FEBS Lett (1988) 0.98
Apoptotic index and apoptosis influencing proteins bcl-2, mcl-1, bax and caspases 3, 6 and 8 in pancreatic carcinoma. Histopathology (1998) 0.98
Claudins in differential diagnosis between mesothelioma and metastatic adenocarcinoma of the pleura. J Clin Pathol (2006) 0.98
Gelatinases and their tissue inhibitors in ovarian tumors; TIMP-1 is a predictive as well as a prognostic factor. Gynecol Oncol (2005) 0.98
Cell specific expression of peroxiredoxins in human lung and pulmonary sarcoidosis. Thorax (2002) 0.98
Matrix metalloproteinase-2 (MMP-2) is associated with the risk for a relapse in postmenopausal patients with node-positive breast carcinoma treated with antiestrogen adjuvant therapy. Breast Cancer Res Treat (2001) 0.96
Manganese superoxide dismutase and catalase are coordinately expressed in the alveolar region in chronic interstitial pneumonias and granulomatous diseases of the lung. Am J Respir Crit Care Med (2000) 0.96
Atypical bronchopulmonary carcinoids show a tendency toward increased apoptotic and proliferative activity. Cancer (2000) 0.96
Expression of gamma-glutamyl cysteine synthetase in nonsmall cell lung carcinoma. Cancer (2001) 0.96
Apoptosis is inversely related to bcl-2 but not to bax expression in salivary gland tumours. Histopathology (1998) 0.96
Expression of tissue inhibitor of metalloproteinases TIMP-2 in human colorectal cancer--a predictor of tumour stage. Br J Cancer (1997) 0.96
Distribution and mRNA expression of tenascin-C in developing human lung. Am J Respir Cell Mol Biol (2001) 0.95
Modulation of type-IV collagenase activity and invasive behavior of metastatic human melanoma (A2058) cells in vitro by monoclonal antibodies to type-IV collagenase. Int J Cancer (1990) 0.95
Prevalence, severity, and types of pulmonary emphysema in a population of deaths in a Finnish city. Correlation with age, sex and smoking. Scand J Respir Dis (1978) 0.94
Serum matrix metalloproteinase-9 concentration in angiographically assessed coronary artery disease. Scand J Clin Lab Invest (2002) 0.94
Manganese superoxide dismutase, but not CuZn superoxide dismutase, is highly expressed in the granulomas of pulmonary sarcoidosis and extrinsic allergic alveolitis. Am J Respir Crit Care Med (1998) 0.94
Expression of P-glycoprotein in hepatocellular carcinoma: a potential marker of prognosis. J Clin Pathol (1996) 0.93
Chronic inflammation and elastin degradation in abdominal aortic aneurysm disease: an immunohistochemical and electron microscopic study. Eur J Vasc Endovasc Surg (1998) 0.93
Low p53 protein expression in salivary gland tumours compared with lung carcinomas. Virchows Arch A Pathol Anat Histopathol (1992) 0.93
Apoptosis in operated small cell lung carcinoma is inversely related to tumour necrosis and p53 immunoreactivity. J Pathol (1997) 0.92
Tenascin immunoreactivity as a prognostic marker in usual interstitial pneumonia. Am J Respir Crit Care Med (1996) 0.92
Urinary type IV collagenase: elevated levels are associated with bladder transitional cell carcinoma. Cancer Epidemiol Biomarkers Prev (1993) 0.92
MMP-2 positivity and age less than 40 years increases the risk for recurrence in premenopausal patients with node-positive breast carcinoma. Breast Cancer Res Treat (1999) 0.91
Manganese superoxide dismutase is increased in the airways of smokers' lungs. Eur Respir J (2004) 0.91
Cytochrome P4502A6 (CYP2A6) expression in human hepatocellular carcinoma. Hepatology (1998) 0.91
Presence of human papillomavirus DNA and abnormal p53 protein accumulation in lung carcinoma. Thorax (1996) 0.90
Gelatinase A-immunoreactive protein in ovarian lesions- prognostic value in epithelial ovarian cancer. Gynecol Oncol (1999) 0.90
Structural relationship between DNA polymerases epsilon and epsilon* and their occurrence in eukaryotic cells. Nucleic Acids Res (1995) 0.90
Expression of caspases-3, -6 and -8 and their relation to apoptosis in non-small cell lung carcinoma. Int J Cancer (2001) 0.90
Expression of inducible nitric oxide synthase in healthy pleura and in malignant mesothelioma. Br J Cancer (2000) 0.90
Fibroblasts stimulate human ovarian cancer cell invasion and expression of 72-kDa gelatinase A (MMP-2). Gynecol Oncol (1997) 0.89
Ovarian cancer cell invasion is inhibited by paclitaxel. Clin Exp Metastasis (1997) 0.89
Prognostic significance of extracellular matrix metalloproteinase inducer and matrix metalloproteinase 2 in epithelial ovarian cancer. Tumour Biol (2007) 0.89
Modulation of M(r) 72,000 and M(r) 92,000 type-IV collagenase (gelatinase A and B) gene expression by interferons alpha and gamma in human melanoma. Int J Cancer (1994) 0.89
p53 immunohistochemistry in malignant fibrous histiocytomas and other mesenchymal tumours. J Pathol (1992) 0.89
Tenascin expression and distribution in pleural inflammatory and fibrotic diseases. J Histochem Cytochem (2000) 0.89
p53 protein expression is correlated with benzo[a]pyrene-DNA adducts in carcinoma cell lines. Carcinogenesis (1995) 0.89
Expression and regulation of hemeoxygenase 1 in healthy human lung and interstitial lung disorders. Hum Pathol (2001) 0.88
The extent of apoptosis is inversely associated with bcl-2 expression in premalignant and malignant breast lesions. Histopathology (1997) 0.88
Expression of p53 protein before and after PUVA treatment in psoriasis. Acta Derm Venereol (1999) 0.88
Matrix metalloproteinase-2 (MMP-2) immunoreactive protein--a new prognostic marker in uveal melanoma? J Pathol (1999) 0.88
Type III and type I procollagen markers in fibrosing alveolitis. Am J Respir Crit Care Med (1999) 0.88
Protein synthesis but not DNA synthesis is required for tumor cell invasion in vitro. Invasion Metastasis (1984) 0.88