Published in Naturwissenschaften on August 01, 1998
Attenuated sensitivity to neuroactive steroids in gamma-aminobutyrate type A receptor delta subunit knockout mice. Proc Natl Acad Sci U S A (1999) 2.88
Isolation, characterization, and purification to homogeneity of an endogenous polypeptide with agonistic action on benzodiazepine receptors. Proc Natl Acad Sci U S A (1983) 2.76
Reelin is preferentially expressed in neurons synthesizing gamma-aminobutyric acid in cortex and hippocampus of adult rats. Proc Natl Acad Sci U S A (1998) 2.18
Increase in the cerebrospinal fluid content of neurosteroids in patients with unipolar major depression who are receiving fluoxetine or fluvoxamine. Proc Natl Acad Sci U S A (1998) 2.12
New concepts on the mechanism of action of benzodiazepines. Life Sci (1975) 2.01
An epigenetic mouse model for molecular and behavioral neuropathologies related to schizophrenia vulnerability. Proc Natl Acad Sci U S A (2002) 1.91
Clozapine and sulpiride but not haloperidol or olanzapine activate brain DNA demethylation. Proc Natl Acad Sci U S A (2008) 1.74
Diazepam binding inhibitor (DBI): a peptide with multiple biological actions. Life Sci (1991) 1.71
DNA-methyltransferase 1 mRNA is selectively overexpressed in telencephalic GABAergic interneurons of schizophrenia brains. Proc Natl Acad Sci U S A (2003) 1.71
The benzamide MS-275 is a potent, long-lasting brain region-selective inhibitor of histone deacetylases. Proc Natl Acad Sci U S A (2006) 1.71
Nicotine decreases DNA methyltransferase 1 expression and glutamic acid decarboxylase 67 promoter methylation in GABAergic interneurons. Proc Natl Acad Sci U S A (2008) 1.65
The activation of inositol phospholipid metabolism as a signal-transducing system for excitatory amino acids in primary cultures of cerebellar granule cells. J Neurosci (1986) 1.61
Molecular mechanisms in the receptor action of benzodiazepines. Annu Rev Pharmacol Toxicol (1979) 1.59
Reelin and glutamic acid decarboxylase67 promoter remodeling in an epigenetic methionine-induced mouse model of schizophrenia. Proc Natl Acad Sci U S A (2005) 1.56
Fractal morphology, imaging and mass spectrometry of single aerosol particles in flight. Nature (2012) 1.56
The influences of andrenotropic drugs and noradrenaline on the histamine release in cardiac anaphylaxis in vitro. J Physiol (1966) 1.54
Delayed increase of Ca2+ influx elicited by glutamate: role in neuronal death. Mol Pharmacol (1989) 1.53
Histone hyperacetylation induces demethylation of reelin and 67-kDa glutamic acid decarboxylase promoters. Proc Natl Acad Sci U S A (2007) 1.51
REELIN and schizophrenia: a disease at the interface of the genome and the epigenome. Mol Interv (2002) 1.49
Dendritic spine hypoplasticity and downregulation of reelin and GABAergic tone in schizophrenia vulnerability. Neurobiol Dis (2001) 1.44
Fluoxetine-elicited changes in brain neurosteroid content measured by negative ion mass fragmentography. Proc Natl Acad Sci U S A (1996) 1.42
Down-regulation of dendritic spine and glutamic acid decarboxylase 67 expressions in the reelin haploinsufficient heterozygous reeler mouse. Proc Natl Acad Sci U S A (2001) 1.42
Cortical bitufted, horizontal, and Martinotti cells preferentially express and secrete reelin into perineuronal nets, nonsynaptically modulating gene expression. Proc Natl Acad Sci U S A (1999) 1.42
Brain 5alpha-dihydroprogesterone and allopregnanolone synthesis in a mouse model of protracted social isolation. Proc Natl Acad Sci U S A (2001) 1.41
CSF biochemistries, glucose metabolism, and diurnal activity rhythms in alcoholic, violent offenders, fire setters, and healthy volunteers. Arch Gen Psychiatry (1994) 1.41
Selective epigenetic alteration of layer I GABAergic neurons isolated from prefrontal cortex of schizophrenia patients using laser-assisted microdissection. Mol Psychiatry (2007) 1.39
[Decision to use complementary medicine: fact oriented or irrational?]. Dtsch Med Wochenschr (1996) 1.39
Colocalization of integrin receptors and reelin in dendritic spine postsynaptic densities of adult nonhuman primate cortex. Proc Natl Acad Sci U S A (2000) 1.36
Pathological gambling. A psychobiological study. Arch Gen Psychiatry (1988) 1.33
Reelin secretion from glutamatergic neurons in culture is independent from neurotransmitter regulation. Proc Natl Acad Sci U S A (2000) 1.33
Cloning and expression of cDNA for human diazepam binding inhibitor, a natural ligand of an allosteric regulatory site of the gamma-aminobutyric acid type A receptor. Proc Natl Acad Sci U S A (1986) 1.32
Nanoscale spin reversal by non-local angular momentum transfer following ultrafast laser excitation in ferrimagnetic GdFeCo. Nat Mater (2013) 1.31
Gas chromatographic-mass fragmentographic quantitation of 3 alpha-hydroxy-5 alpha-pregnan-20-one (allopregnanolone) and its precursors in blood and brain of adrenalectomized and castrated rats. J Neurosci (1995) 1.31
Evidence for involvement of GABA in the action of benzodiazepines: studies on rat cerebellum. Adv Biochem Psychopharmacol (1975) 1.30
The phenotypic characteristics of heterozygous reeler mouse. Neuroreport (1999) 1.29
Study of an octadecaneuropeptide derived from diazepam binding inhibitor (DBI): biological activity and presence in rat brain. Proc Natl Acad Sci U S A (1986) 1.26
Diazepam binding inhibitor and its processing products stimulate mitochondrial steroid biosynthesis via an interaction with mitochondrial benzodiazepine receptors. Endocrinology (1991) 1.26
Permissive role of brain allopregnanolone content in the regulation of pentobarbital-induced righting reflex loss. Neuropharmacology (1999) 1.23
Focussed microwave radiation: a technique to minimize post mortem changes of cyclic nucleotides, dopa and choline and to preserve brain morphology. Neuropharmacology (1974) 1.23
Mechanisms by which diazepam, muscimol, and other drugs change the content of cGMP in cerebellar cortex. Proc Natl Acad Sci U S A (1977) 1.23
Gangliosides prevent glutamate and kainate neurotoxicity in primary neuronal cultures of neonatal rat cerebellum and cortex. Proc Natl Acad Sci U S A (1988) 1.21
Modulation of nicotinic receptors by opiate receptor agonists in cultured adrenal chromaffin cells. Nature (1980) 1.20
Intrinsic GABAergic system of adrenal chromaffin cells. Proc Natl Acad Sci U S A (1984) 1.20
Expression of reelin in adult mammalian blood, liver, pituitary pars intermedia, and adrenal chromaffin cells. Proc Natl Acad Sci U S A (2000) 1.20
Modifications of gamma-aminobutyric acidA receptor subunit expression in rat neocortex during tolerance to diazepam. Mol Pharmacol (1996) 1.19
Stimulation of food intake by muscimol and beta endorphin. Neuropharmacology (1977) 1.19
On a brain polypeptide functioning as a putative effector for the recognition sites of benzodiazepine and beta-carboline derivatives. Neuropharmacology (1983) 1.18
A substance P (neurokinin-1) receptor mutant carboxyl-terminally truncated to resemble a naturally occurring receptor isoform displays enhanced responsiveness and resistance to desensitization. Proc Natl Acad Sci U S A (1997) 1.18
Pregnenolone biosynthesis in C6-2B glioma cell mitochondria: regulation by a mitochondrial diazepam binding inhibitor receptor. Proc Natl Acad Sci U S A (1992) 1.18
Endogenous protein kinase inhibitors. Purification, characterization, and distribution in different tissues. J Biol Chem (1977) 1.17
Molecular mechanisms mediating the action of diazepam on GABA receptors. Br J Psychiatry (1978) 1.16
Simultaneous isolation of adenosine 3',5'-cyclic monophosphate (cAMP) and guanosine 3',5'-cyclic monophosphate (cGMP) in small tissue samples. Anal Biochem (1974) 1.14
A GABAergic cortical deficit dominates schizophrenia pathophysiology. Crit Rev Neurobiol (2004) 1.14
On the putative physiological role of allopregnanolone on GABA(A) receptor function. Neuropharmacology (2003) 1.13
Modulation of rat brain cytosolic phosphatidate phosphohydrolase: effect of cationic amphiphilic drugs and divalent cations. Arch Biochem Biophys (1987) 1.12
An endogenous protein modulates the affinity of GABA and benzodiazepine receptors in rat brain. Nature (1978) 1.12
Cyclic GMP: reduction of cerebellar concentrations in "nervous" mutant mice. Brain Res (1975) 1.11
Diazepam-binding inhibitor: a neuropeptide located in selected neuronal populations of rat brain. Science (1985) 1.10
Nanoplasma dynamics of single large xenon clusters irradiated with superintense x-ray pulses from the linac coherent light source free-electron laser. Phys Rev Lett (2012) 1.08
Distribution and metabolism of muscimol in the brain and other tissues of the rat. Neuropharmacology (1979) 1.07
A brain octadecaneuropeptide generated by tryptic digestion of DBI (diazepam binding inhibitor) functions as a proconflict ligand of benzodiazepine recognition sites. Neuropharmacology (1984) 1.06
Molecular cloning and expression of cDNA encoding a peripheral-type benzodiazepine receptor. J Biol Chem (1989) 1.06
Potentiation of morphine analgesia by muscimol. Neuropharmacology (1977) 1.06
Benzodiazepines on trial: a research strategy for their rehabilitation. Trends Pharmacol Sci (1996) 1.06
An upregulation of DNA-methyltransferase 1 and 3a expressed in telencephalic GABAergic neurons of schizophrenia patients is also detected in peripheral blood lymphocytes. Schizophr Res (2009) 1.04
Brain allopregnanolone regulates the potency of the GABA(A) receptor agonist muscimol. Neuropharmacology (2000) 1.03
2-Aryl-3-indoleacetamides (FGIN-1): a new class of potent and specific ligands for the mitochondrial DBI receptor (MDR). J Pharmacol Exp Ther (1992) 1.03
Distribution and characterization of diazepam binding inhibitor (DBI) in peripheral tissues of rat. Regul Pept (1990) 1.03
Gangliosides normalize distorted single-cell intracellular free Ca2+ dynamics after toxic doses of glutamate in cerebellar granule cells. Proc Natl Acad Sci U S A (1990) 1.03
beta-Carbolines enhance shock-induced suppression of drinking in rats. Proc Natl Acad Sci U S A (1983) 1.02
Adenosine 3',5'-monophosphate concentrations and isoproterenol-induced synthesis of deoxyribonucleic acid in mouse parotid gland. Mol Pharmacol (1972) 1.02
Climbing fiver activation and 3', 5'-cyclic guanosine monophosphate (cGMP) content in cortex and deep nuclei of cerebellum. Brain Res (1976) 1.02
Propranolol-induced inhibition of rat brain cytoplasmic phosphatidate phosphohydrolase. Neurochem Res (1983) 1.01
Involvement of adenosine 3',5'-monophosphate in the activation of tyrosine hydroxylase elicited by drugs. Science (1973) 1.01
Glutamic acid decarboxylase and glutamate receptor changes during tolerance and dependence to benzodiazepines. Proc Natl Acad Sci U S A (2001) 1.01
Stimulation by local anesthetics of the metabolism of acidic phospholipids in the rat pineal gland. Biochem Biophys Res Commun (1974) 1.01
7-Chloro-3-methyl-3-4-dihydro-2H-1,2,4 benzothiadiazine S,S-dioxide (IDRA 21): a benzothiadiazine derivative that enhances cognition by attenuating DL-alpha-amino-2,3-dihydro-5-methyl-3-oxo-4-isoxazolepropanoic acid (AMPA) receptor desensitization. J Pharmacol Exp Ther (1995) 1.01
Commentary: Trans-synaptic regulation of typrosine 3-mono-oxygenase biosynthesis in rat adrenal medulla. Biochem Pharmacol (1977) 1.00
Taurine distribution in cat brain. J Neurochem (1972) 1.00
Enhanced dizocilpine efficacy in heterozygous reeler mice relates to GABA turnover downregulation. Neuropharmacology (2004) 1.00
Isolation and characterization of a rat brain triakontatetraneuropeptide, a posttranslational product of diazepam binding inhibitor: specific action at the Ro 5-4864 recognition site. J Neurochem (1989) 1.00
Endogenous benzodiazepine receptor ligands in idiopathic recurring stupor. Lancet (1992) 1.00
Regional and interspecies differences in brain progesterone metabolism. J Neurochem (1993) 0.99
Characterization of benzodiazepine and gamma-aminobutyric recognition sites and their endogenous modulators. J Neurosci (1981) 0.99
A role for nicotinic receptors in the regulation of the adenylate cyclase of adrenal medulla. J Pharmacol Exp Ther (1974) 0.98
Changes in AMPA receptor-spliced variant expression and shift in AMPA receptor spontaneous desensitization pharmacology during cerebellar granule cell maturation in vitro. J Mol Neurosci (1998) 0.98
Glutamate-induced neuronal death in primary cultures of cerebellar granule cells: protection by synthetic derivatives of endogenous sphingolipids. J Pharmacol Exp Ther (1990) 0.98
Stimulation of 32 P i incorporation into phosphatidylinositol and phosphatidyglycerol by catecholamines and -adrenergic receptor blocking agents in rat pineal organ cultures. J Biol Chem (1973) 0.98
Personality profiles and state aggressiveness in Finnish alcoholic, violent offenders, fire setters, and healthy volunteers. Arch Gen Psychiatry (1994) 0.97
Isolation, characterization, and purification to homogeneity of a rat brain protein (GABA-modulin). Proc Natl Acad Sci U S A (1982) 0.97
Involvement of 3',5'-cyclic adenosine monophosphate in the increase of tyrosine hydroxylase activity elicited by cold exposure. Naunyn Schmiedebergs Arch Pharmacol (1973) 0.97
Tolerance to diazepam and changes in GABA(A) receptor subunit expression in rat neocortical areas. Neuroscience (1997) 0.97
Do cyclic nucleotides promote the trans-synaptic induction of tyrosine hydroxylase? Life Sci (1974) 0.97
Regional distribution of polyphosphoinositides in rat brain. Biochim Biophys Acta (1971) 0.96
The pharmacology of neurosteroidogenesis. J Steroid Biochem Mol Biol (1994) 0.96
Purification of an endogenous protein inhibitor of the high affinity binding of gamma-aminobutyric acid to synaptic membranes of rat brain. Proc Natl Acad Sci U S A (1978) 0.96
Energy- and sodium-dependent uptake of inositol by kidney cortex slices. Biochem Biophys Res Commun (1965) 0.96
Intrinsic gamma aminobutyric acid receptors modulate the release of catecholamine from canine adrenal gland in situ. J Pharmacol Exp Ther (1986) 0.95
Stimulation of brain pregnenolone synthesis by mitochondrial diazepam binding inhibitor receptor ligands in vivo. J Neurochem (1993) 0.95
7-Chloro-3-methyl-3,4-dihydro-2H-1,2,4-benzothiadiazine S,S-dioxide (IDRA 21), a congener of aniracetam, potently abates pharmacologically induced cognitive impairments in patas monkeys. Proc Natl Acad Sci U S A (1995) 0.95