Published in Arterioscler Thromb Vasc Biol on October 01, 1998
Massive xanthomatosis and altered composition of atherosclerotic lesions in hyperlipidemic mice lacking acyl CoA:cholesterol acyltransferase 1. J Clin Invest (2000) 2.21
Acyl-coenzyme A:cholesterol acyltransferases. Am J Physiol Endocrinol Metab (2009) 1.85
Increased atherosclerosis in LDL receptor-null mice lacking ACAT1 in macrophages. J Clin Invest (2001) 1.83
Multiple functions of microsomal triglyceride transfer protein. Nutr Metab (Lond) (2012) 1.47
Localization of human acyl-coenzyme A: cholesterol acyltransferase-1 (ACAT-1) in macrophages and in various tissues. Am J Pathol (2000) 1.12
Akt3 deficiency in macrophages promotes foam cell formation and atherosclerosis in mice. Cell Metab (2012) 1.07
Investigating the allosterism of acyl-CoA:cholesterol acyltransferase (ACAT) by using various sterols: in vitro and intact cell studies. Biochem J (2005) 1.06
Microsomal triglyceride transfer protein enhances cellular cholesteryl esterification by relieving product inhibition. J Biol Chem (2008) 1.05
Acyl-coenzyme A:cholesterol acyltransferase promotes oxidized LDL/oxysterol-induced apoptosis in macrophages. J Lipid Res (2005) 0.98
TNF-alpha stimulates the ACAT1 expression in differentiating monocytes to promote the CE-laden cell formation. J Lipid Res (2009) 0.93
Human acyl-CoA:cholesterol acyltransferase 2 gene expression in intestinal Caco-2 cells and in hepatocellular carcinoma. Biochem J (2006) 0.93
Cholesterol loading in macrophages stimulates formation of ER-derived vesicles with elevated ACAT1 activity. J Lipid Res (2010) 0.88
Differential expression of genes and changes in glucose metabolism in the liver of liver-specific glucokinase gene knockout mice. Gene (2013) 0.85
Modulation peroxisome proliferators activated receptor alpha (PPAR alpha) and acyl coenzyme A: cholesterol acyltransferase1 (ACAT1) gene expression by fatty acids in foam cell. Lipids Health Dis (2009) 0.79
Low-level expression of human ACAT2 gene in monocytic cells is regulated by the C/EBP transcription factors. Acta Biochim Biophys Sin (Shanghai) (2016) 0.77
ACAT1/SOAT1 as a therapeutic target for Alzheimer's disease. Future Med Chem (2015) 0.77
Tissue cholesterol content alterations in streptozotocin-induced diabetic rats. Acta Pharmacol Sin (2012) 0.76
ACAT1-associated Late Endosomes/Lysosomes Significantly Improve Impaired Intracellular Cholesterol Metabolism and the Survival of Niemann-Pick Type C Mice. Acta Histochem Cytochem (2014) 0.75
Genetics and molecular biology: macrophage ACAT depletion - mechanisms of atherogenesis. Curr Opin Lipidol (2006) 0.75
Direct effect of an acyl-CoA:cholesterol acyltransferase inhibitor, F-1394, on atherosclerosis in apolipoprotein E and low density lipoprotein receptor double knockout mice. Br J Pharmacol (2001) 0.75
Differential lipid metabolism in monocytes and macrophages: influence of cholesterol loading. J Lipid Res (2016) 0.75
The systems biology markup language (SBML): a medium for representation and exchange of biochemical network models. Bioinformatics (2003) 32.92
The optimization principle in phylogenetic analysis tends to give incorrect topologies when the number of nucleotides or amino acids used is small. Proc Natl Acad Sci U S A (1998) 15.43
2012 revised International Chapel Hill Consensus Conference Nomenclature of Vasculitides. Arthritis Rheum (2013) 11.18
Niemann-Pick C1 disease gene: homology to mediators of cholesterol homeostasis. Science (1997) 6.66
Surface density of calcium ions and calcium spikes in the barnacle muscle fiber membrane. J Gen Physiol (1967) 6.59
The anomalous rectification and cation selectivity of the membrane of a starfish egg cell. J Membr Biol (1974) 6.43
E-CELL: software environment for whole-cell simulation. Bioinformatics (1999) 6.29
Epilepsy and exacerbation of brain injury in mice lacking the glutamate transporter GLT-1. Science (1997) 5.13
Bidirectional SV40 transcription mediated by tandem Sp1 binding interactions. Science (1985) 5.00
Requirement of stereospecific alignments for initiation from the simian virus 40 early promoter. Nature (1986) 4.77
Regulation of DNA-replication origins during cell-cycle progression. Nature (1998) 4.52
A serine protease, HtrA2, is released from the mitochondria and interacts with XIAP, inducing cell death. Mol Cell (2001) 4.24
B cell lymphoma-associated chromosomal translocation involves candidate oncogene lyt-10, homologous to NF-kappa B p50. Cell (1991) 3.84
Association of low-energy femoral fractures with prolonged bisphosphonate use: a case control study. Osteoporos Int (2008) 3.80
Immunochemical structure of hepatitis B e antigen in the serum. J Immunol (1983) 3.50
Post-tetanic hyperpolarization and electrogenic Na pump in stretch receptor neurone of crayfish. J Physiol (1966) 3.42
Variant of penicillinase mediated by an R factor in Escherichia coli. J Bacteriol (1970) 3.33
Recombinant immune interferon increases immunoglobulin G Fc receptors on cultured human mononuclear phagocytes. J Clin Invest (1983) 3.32
Complementation cloning of S2P, a gene encoding a putative metalloprotease required for intramembrane cleavage of SREBPs. Mol Cell (1997) 3.29
Scrape-loading and dye transfer. A rapid and simple technique to study gap junctional intercellular communication. Exp Cell Res (1987) 3.28
Il-6 and its soluble receptor orchestrate a temporal switch in the pattern of leukocyte recruitment seen during acute inflammation. Immunity (2001) 3.27
Purification and characterization of a novel type of fimbriae from the oral anaerobe Bacteroides gingivalis. J Bacteriol (1984) 3.27
Molecular cloning and sequence analysis of cDNA for human hepatocyte growth factor. Biochem Biophys Res Commun (1989) 3.21
BCL-6 protein is expressed in germinal-center B cells. Blood (1995) 3.18
In vitro and in vivo activities of anti-influenza virus compound T-705. Antimicrob Agents Chemother (2002) 3.17
Value of ICD-9 coded chief complaints for detection of epidemics. Proc AMIA Symp (2001) 3.13
Evolutionary motif and its biological and structural significance. J Mol Evol (1997) 3.03
Molecular cloning of a porcine gene syk that encodes a 72-kDa protein-tyrosine kinase showing high susceptibility to proteolysis. J Biol Chem (1991) 2.89
Mis6, a fission yeast inner centromere protein, acts during G1/S and forms specialized chromatin required for equal segregation. Cell (1997) 2.88
cAMP-GEFII is a direct target of cAMP in regulated exocytosis. Nat Cell Biol (2000) 2.83
Specific protein binding to the simian virus 40 enhancer in vitro. Mol Cell Biol (1986) 2.82
Bni1p and Bnr1p: downstream targets of the Rho family small G-proteins which interact with profilin and regulate actin cytoskeleton in Saccharomyces cerevisiae. EMBO J (1997) 2.80
The soluble interleukin 6 receptor: mechanisms of production and implications in disease. FASEB J (2001) 2.78
Gold determination in biological fluids by atomic absorption spectrophotometry: application to chrysotherapy in rheumatoid arthritis patients. Arthritis Rheum (1968) 2.74
Atomic Control of the SrTiO3 Crystal Surface. Science (1994) 2.72
Primary structure of elongation factor Tu from Escherichia coli. Proc Natl Acad Sci U S A (1980) 2.72
Isolation of Rickettsia tsutsugamushi antigenically different from Kato, Karp, and Gilliam strains from patients. Microbiol Immunol (1984) 2.70
The reaction of phenylglyoxal with arginine residues in proteins. J Biol Chem (1968) 2.67
Calcium and potassium currents of the membrane of a barnacle muscle fibre in relation to the calcium spike. J Physiol (1969) 2.63
Antiproteinuric effect of the calcium channel blocker cilnidipine added to renin-angiotensin inhibition in hypertensive patients with chronic renal disease. Kidney Int (2007) 2.61
Seroepidemiology of human herpesvirus 6 infection in normal children and adults. J Clin Microbiol (1989) 2.58
A novel receptor involved in T-cell activation. Nature (1995) 2.56
Demonstration of hepatitis B e antigen in the core of Dane particles. J Immunol (1979) 2.56
Onset of re-epithelialization after skin injury correlates with a reorganization of keratin filaments in wound edge keratinocytes: defining a potential role for keratin 16. J Cell Biol (1996) 2.49
Towards a combined prognostic index for survival in HIV infection: the role of 'non-HIV' biomarkers. HIV Med (2009) 2.48
Association of structural polymorphisms in the human period3 gene with delayed sleep phase syndrome. EMBO Rep (2001) 2.43
Acyl-coenzyme A:cholesterol acyltransferase. Annu Rev Biochem (1997) 2.41
Three-generation reproductive toxicity study of dietary bisphenol A in CD Sprague-Dawley rats. Toxicol Sci (2002) 2.37
In vivo cerebrovascular measurement combining diffuse near-infrared absorption and correlation spectroscopies. Phys Med Biol (2001) 2.36
Uveal effusion syndrome: clinical features, surgical treatment, histologic examination of the sclera, and pathophysiology. Ophthalmology (2000) 2.36
Non-A, non-B hepatitis specific antibodies directed at host-derived epitope: implication for an autoimmune process. Lancet (1990) 2.35
Membrane currents of the tunicate egg under the voltage-clamp condition. J Physiol (1976) 2.32
Regulation of Ca2+ channel expression at the cell surface by the small G-protein kir/Gem. Nature (2001) 2.28
Prevalence and specificity of LKB1 genetic alterations in lung cancers. Oncogene (2007) 2.27
Linkage of decreased bone mass with impaired osteoblastogenesis in a murine model of accelerated senescence. J Clin Invest (1996) 2.26
The voltage-sensitive sodium channel is a bell-shaped molecule with several cavities. Nature (2001) 2.23
Two components of the calcium current in the egg cell membrane of the tunicate. J Physiol (1976) 2.22
Purification and partial characterization of hepatocyte growth factor from plasma of a patient with fulminant hepatic failure. J Clin Invest (1988) 2.22
Analysis of polypeptide composition and antigenic components of Rickettsia tsutsugamushi by polyacrylamide gel electrophoresis and immunoblotting. Infect Immun (1985) 2.20
Human monocytes express CD163, which is upregulated by IL-10 and identical to p155. Cytokine (2000) 2.18
Time to recurrence after recovery from major depressive episodes and its predictors. Psychol Med (2003) 2.14
Telaprevir-based triple therapy for chronic hepatitis C patients with advanced fibrosis: a prospective clinical study. Aliment Pharmacol Ther (2013) 2.13
Faithful anaphase is ensured by Mis4, a sister chromatid cohesion molecule required in S phase and not destroyed in G1 phase. Genes Dev (1998) 2.10
Slow and fast groups of pyramidal tract cells and their respective membrane properties. J Neurophysiol (1965) 2.09
Anti-angiogenic cues from vascular basement membrane collagen. Cancer Res (2000) 2.06
Effects of internal free calcium upon the sodium and calcium channels in the tunicate egg analysed by the internal perfusion technique. J Physiol (1978) 2.05
Structure and function of chicken gizzard myosin. J Biochem (1978) 2.05
Increase of maximum life-span in Sweden, 1861-1999. Science (2000) 2.04
Mechanical detachment of the anterior hyaloid membrane from the posterior lens capsule. Ophthalmology (2001) 2.04
Serum pepsinogens as a screening test of extensive chronic gastritis. Gastroenterol Jpn (1987) 2.03
Calcium and sodium contributions to regenerative responses in the embryonic excitable cell membrane. Science (1972) 2.03
Rho1p-Bni1p-Spa2p interactions: implication in localization of Bni1p at the bud site and regulation of the actin cytoskeleton in Saccharomyces cerevisiae. Mol Biol Cell (1998) 2.01
Electrical excitability in the egg cell membrane of the tunicate. J Physiol (1974) 1.99
Formation of the male-specific muscle in female Drosophila by ectopic fruitless expression. Nat Cell Biol (2000) 1.99
Analysis of non-linearity observed in the current-voltage relation of the tunicate embryo. J Physiol (1974) 1.97
Afadin: A key molecule essential for structural organization of cell-cell junctions of polarized epithelia during embryogenesis. J Cell Biol (1999) 1.96
Acyl-coenzyme A: cholesterol acyltransferase modulates the generation of the amyloid beta-peptide. Nat Cell Biol (2001) 1.96
Outbreak of cefozopran (penicillin, oral cephems, and aztreonam)-resistant Neisseria gonorrhoeae in Japan. Antimicrob Agents Chemother (2001) 1.95
Pigment epithelium-derived factor inhibits retinal and choroidal neovascularization. J Cell Physiol (2001) 1.94
Chromosomal translocations cause deregulated BCL6 expression by promoter substitution in B cell lymphoma. EMBO J (1995) 1.94
Dental pulp cells for induced pluripotent stem cell banking. J Dent Res (2010) 1.92
Transcriptional repression of Stat6-dependent interleukin-4-induced genes by BCL-6: specific regulation of iepsilon transcription and immunoglobulin E switching. Mol Cell Biol (1999) 1.91
Determination of free amino acid enantiomers in rat brain and serum by high-performance liquid chromatography after derivatization with N-tert.-butyloxycarbonyl-L-cysteine and o-phthaldialdehyde. J Chromatogr (1992) 1.91
Video-assisted thoracoscopic surgery for small indeterminate pulmonary nodules: indications for preoperative marking. Chest (1999) 1.90
Excitation-contraction coupling in a barnacle muscle fiber as examined with voltage clamp technique. J Gen Physiol (1968) 1.90
Functional expression and tissue distribution of a novel receptor for vasoactive intestinal polypeptide. Neuron (1992) 1.90
Identification and characterization of genes associated with human hepatocellular carcinogenesis. Cancer Res (1999) 1.88
An alternative to journal-based impact factors. Occup Med (Lond) (1999) 1.87
Mesangial cell, glomerular and renal vascular responses to endothelin in the rat kidney. Elucidation of signal transduction pathways. J Clin Invest (1989) 1.85
Modulation of hematopoiesis in mice with a truncated mutant of the interleukin-2 receptor gamma chain. Blood (1996) 1.85
Activated human T cells directly induce osteoclastogenesis from human monocytes: possible role of T cells in bone destruction in rheumatoid arthritis patients. Arthritis Rheum (2001) 1.85
Direct measurement of the force of microtubule sliding in flagella. Nature (1981) 1.85
Nectin-3, a new member of immunoglobulin-like cell adhesion molecules that shows homophilic and heterophilic cell-cell adhesion activities. J Biol Chem (2000) 1.84
Enthalpy and heat capacity changes for the proton dissociation of various buffer components in 0.1 M potassium chloride. Proteins (1998) 1.84
All six GC-motifs of the SV40 early upstream element contribute to promoter activity in vivo and in vitro. EMBO J (1985) 1.84
Identification of a second class of IgG Fc receptors on human neutrophils. A 40 kilodalton molecule also found on eosinophils. J Exp Med (1986) 1.82
Neurabin-II/spinophilin. An actin filament-binding protein with one pdz domain localized at cadherin-based cell-cell adhesion sites. J Biol Chem (1998) 1.82