Published in Prog Neurobiol on December 01, 1998
Nerve growth factor: from the early discoveries to the potential clinical use. J Transl Med (2012) 1.69
The significance of the cholinergic system in the brain during aging and in Alzheimer's disease. J Neural Transm (Vienna) (2006) 1.50
Nerve growth factor and galantamine ameliorate early signs of neurodegeneration in anti-nerve growth factor mice. Proc Natl Acad Sci U S A (2002) 1.17
Histone deacetylase inhibitor valproic acid inhibits cancer cell proliferation via down-regulation of the alzheimer amyloid precursor protein. J Biol Chem (2010) 1.14
AlzPathway: a comprehensive map of signaling pathways of Alzheimer's disease. BMC Syst Biol (2012) 1.13
Increasing CREB function in the CA1 region of dorsal hippocampus rescues the spatial memory deficits in a mouse model of Alzheimer's disease. Neuropsychopharmacology (2011) 1.08
Neuroprotective strategies in Alzheimer's disease. NeuroRx (2004) 1.05
Revisiting the Role of Acetylcholinesterase in Alzheimer's Disease: Cross-Talk with P-tau and β-Amyloid. Front Mol Neurosci (2011) 0.97
Reduction of beta-amyloid levels by novel protein kinase C(epsilon) activators. J Biol Chem (2009) 0.95
Rapid β-amyloid deposition and cognitive impairment after cholinergic denervation in APP/PS1 mice. J Neuropathol Exp Neurol (2013) 0.92
Quantitative proteomic analyses of cerebrospinal fluid using iTRAQ in a primate model of iron deficiency anemia. Dev Neurosci (2012) 0.86
Distinct glutaminyl cyclase expression in Edinger-Westphal nucleus, locus coeruleus and nucleus basalis Meynert contributes to pGlu-Abeta pathology in Alzheimer's disease. Acta Neuropathol (2010) 0.83
Stable beta-secretase activity and presynaptic cholinergic markers during progressive central nervous system amyloidogenesis in Tg2576 mice. Am J Pathol (2002) 0.83
New insights into huperzine A for the treatment of Alzheimer's disease. Acta Pharmacol Sin (2012) 0.82
Huperzine A: Is it an Effective Disease-Modifying Drug for Alzheimer's Disease? Front Aging Neurosci (2014) 0.82
Non-cholinergic effects of huperzine A: beyond inhibition of acetylcholinesterase. Cell Mol Neurobiol (2007) 0.81
The modular systems biology approach to investigate the control of apoptosis in Alzheimer's disease neurodegeneration. BMC Neurosci (2006) 0.80
GRK5 deficiency accelerates {beta}-amyloid accumulation in Tg2576 mice via impaired cholinergic activity. J Biol Chem (2010) 0.80
MicroRNA expression profile in exosome discriminates extremely severe infections from mild infections for hand, foot and mouth disease. BMC Infect Dis (2014) 0.80
Presenilin 1 interacts with acetylcholinesterase and alters its enzymatic activity and glycosylation. Mol Cell Biol (2008) 0.78
Cholinergic Mechanisms in the Cerebral Cortex: Beyond Synaptic Transmission. Neuroscientist (2015) 0.78
Perspectives in molecular imaging using staging biomarkers and immunotherapies in Alzheimer's disease. ScientificWorldJournal (2013) 0.78
Paradoxical effect of TrkA inhibition in Alzheimer's disease models. J Alzheimers Dis (2014) 0.77
Therapeutic perspectives of drugs targeting Toll-like receptors based on immune physiopathology theory of Alzheimer's disease. CNS Neurol Disord Drug Targets (2014) 0.75
Impaired NGF/TrkA Signaling Causes Early AD-Linked Presynaptic Dysfunction in Cholinergic Primary Neurons. Front Cell Neurosci (2017) 0.75
Follicular fluid Aβ40 concentrations may be associated with ongoing pregnancy following in vitro fertilization. J Assist Reprod Genet (2014) 0.75
Loss of neurons in the nucleus basalis of Meynert in Alzheimer's disease, paralysis agitans and Korsakoff's Disease. Acta Neuropathol (1983) 1.91
Plastic neuronal remodeling is impaired in patients with Alzheimer's disease carrying apolipoprotein epsilon 4 allele. J Neurosci (1997) 1.73
Neuronal loss in different parts of the nucleus basalis is related to neuritic plaque formation in cortical target areas in Alzheimer's disease. Neuroscience (1985) 1.59
Cholinergic projections from the basal forebrain to frontal, parietal, temporal, occipital, and cingulate cortices: a combined fluorescent tracer and acetylcholinesterase analysis. Brain Res Bull (1982) 1.51
Experimental traumatic brain injury in rats stimulates the expression, production and activity of Alzheimer's disease beta-secretase (BACE-1). J Neural Transm (Vienna) (2004) 1.47
Beta-amyloid-induced glial expression of both pro- and anti-inflammatory cytokines in cerebral cortex of aged transgenic Tg2576 mice with Alzheimer plaque pathology. Brain Res (2001) 1.37
Induction of cytokines in glial cells surrounding cortical beta-amyloid plaques in transgenic Tg2576 mice with Alzheimer pathology. Int J Dev Neurosci (2000) 1.32
Early postnatal development of rat brain: in vivo diffusion tensor imaging. J Neurosci Res (2008) 1.31
Rodent model of chronic central pain after spinal cord contusion injury and effects of gabapentin. J Neurotrauma (2000) 1.23
Systemic administration of defined extracts from Withania somnifera (Indian Ginseng) and Shilajit differentially affects cholinergic but not glutamatergic and GABAergic markers in rat brain. Neurochem Int (1997) 1.21
Resolvin E1 protects the rat heart against reperfusion injury. Am J Physiol Heart Circ Physiol (2010) 1.20
Neuronal and glial beta-secretase (BACE) protein expression in transgenic Tg2576 mice with amyloid plaque pathology. J Neurosci Res (2001) 1.20
Circadian clock in culture: N-acetyltransferase activity of chick pineal glands oscillates in vitro. Science (1979) 1.19
DNA microarray analysis of the contused spinal cord: effect of NMDA receptor inhibition. J Neurosci Res (2002) 1.11
Changes in acetylcholinesterase and butyrylcholinesterase in Alzheimer's disease resemble embryonic development--a study of molecular forms. Neurochem Int (1992) 1.10
Chondroitin sulfate proteoglycan-immunoreactivity of lectin-labeled perineuronal nets around parvalbumin-containing neurons. Brain Res (1994) 1.06
Phylogenetic diversity of the expression of the microtubule-associated protein tau: implications for neurodegenerative disorders. Brain Res Mol Brain Res (1999) 1.04
Acute and chronic changes in aquaporin 4 expression after spinal cord injury. Neuroscience (2006) 1.04
Identification and characterization of nuclear factor kappaB binding sites in the murine bcl-x promoter. J Neurochem (2000) 1.03
Expression of beta-secretase mRNA in transgenic Tg2576 mouse brain with Alzheimer plaque pathology. Neurosci Lett (2000) 1.03
Cortical areas are revealed by distribution patterns of proteoglycan components and parvalbumin in the Mongolian gerbil and rat. Brain Res (1994) 1.01
Cholinergic projections from magnocellular nuclei of the basal forebrain to cortical areas in rats. Brain Res (1980) 1.00
Insulin-sensitive GLUT4 glucose transporters are colocalized with GLUT3-expressing cells and demonstrate a chemically distinct neuron-specific localization in rat brain. J Neurosci Res (1999) 0.99
Exogenous Bcl-xL fusion protein spares neurons after spinal cord injury. J Neurosci Res (2005) 0.99
The influence of nerve growth factor on the in vitro proliferative response of rat spleen lymphocytes. J Neurosci Res (1987) 0.99
Activities of key glycolytic enzymes in the brains of patients with Alzheimer's disease. J Neural Transm (Vienna) (1999) 0.98
Developmental patterns of proteoglycan-containing extracellular matrix in perineuronal nets and neuropil of the postnatal rat brain. Cell Tissue Res (1997) 0.97
Aquaporin 1 - a novel player in spinal cord injury. J Neurochem (2008) 0.96
Activated mitogenic signaling induces a process of dedifferentiation in Alzheimer's disease that eventually results in cell death. Ann N Y Acad Sci (2000) 0.94
Inhibition of the neuronal insulin receptor. An in vivo model for sporadic Alzheimer disease? Ann N Y Acad Sci (2000) 0.94
Decreased ratio of CSF acetylcholinesterase to butyrylcholinesterase activity in Alzheimer's disease. Lancet (1984) 0.93
A human clonal cell line model of differentiating neurons. Dev Biol (1979) 0.91
p75 and TrkA receptor signaling independently regulate amyloid precursor protein mRNA expression, isoform composition, and protein secretion in PC12 cells. J Neurochem (1998) 0.91
Liposomal IGF-1 gene transfer modulates pro- and anti-inflammatory cytokine mRNA expression in the burn wound. Gene Ther (2001) 0.91
Distribution of parvalbumin-containing neurons and lectin-binding perineuronal nets in the rat basal forebrain. Brain Res (1993) 0.90
Inhibition of nuclear factor kappa B (NFkappaB) activity induces nerve growth factor-resistant apoptosis in PC12 cells. J Neurosci Res (1997) 0.89
Effect of magnocellular forebrain nuclei lesions on acetylcholine output from the cerebral cortex, electrocorticogram and behaviour. Arch Ital Biol (1982) 0.89
Hypoxia-induced mitochondrial and nuclear DNA damage in the rat brain. J Neurosci Res (1999) 0.89
Characterization of proteoglycan-containing perineuronal nets by enzymatic treatments of rat brain sections. Histochem J (1997) 0.88
Induction of neurite outgrowth in the IMR-32 human neuroblastoma cell line by nerve growth factor. J Neurosci Res (1981) 0.88
Muscarinic acetylcholine receptors activate the acetylcholinesterase gene promoter. J Physiol Paris (1999) 0.88
The physical and biological properties of 7S and beta-NGF from the mouse submaxillary gland. Adv Exp Med Biol (1972) 0.88
Increased expression of brain-derived neurotrophic factor but not neurotrophin-3 mRNA in rat brain after cortical impact injury. J Neurosci Res (1996) 0.87
Pyramidal cells ensheathed by perineuronal nets in human motor and somatosensory cortex. Neuroreport (1996) 0.87
Enhanced matrix degradation after withdrawal of TGF-beta1 triggers hepatocytes from apoptosis to proliferation and regeneration. Cell Prolif (2005) 0.87
Bcl-xL expression after contusion to the rat spinal cord. J Neurotrauma (2001) 0.87
APE/Ref-1 responses to ischemia in rat brain. Neuroreport (1998) 0.87
Amyloid deposition in the nucleus basalis of Meynert complex: a topographic marker for degenerating cell clusters in Alzheimer's disease. Acta Neuropathol (1988) 0.87
Acetyl-L-carnitine enhances the response of PC12 cells to nerve growth factor. Brain Res Dev Brain Res (1991) 0.87
Interleukin-1beta, inducible nitric oxide synthase, and nuclear factor-kappaB are induced in morphologically distinct microglia after rat hippocampal lipopolysaccharide/interferon-gamma injection. J Neurosci Res (1999) 0.86
Normobaric hyperoximia increases hypoxia-induced cerebral injury: DTI study in rats. J Neurosci Res (2010) 0.86
IGF-I gene transfer in thermally injured rats. Gene Ther (1999) 0.86
Dendritic reorganisation in the basal forebrain under degenerative conditions and its defects in Alzheimer's disease. II. Ageing, Korsakoff's disease, Parkinson's disease, and Alzheimer's disease. J Comp Neurol (1995) 0.86
Characterization of functional nerve growth factor-receptors in a CNS glial cell line: monoclonal antibody 217c recognizes the nerve growth factor-receptor on C6 glioma cells. J Neurosci Res (1990) 0.85
BCL-2-related protein expression in apoptosis: oxidative stress versus serum deprivation in PC12 cells. J Neurochem (1997) 0.85
Membrane properties of a human neuroblastoma II: Effects of differentiation. J Neurosci Res (1981) 0.85
Effects of nerve growth factor on the expression of interleukin-2 receptors on cultured human lymphocytes. Ann N Y Acad Sci (1987) 0.85
Expression of p75NGFR TrkA, and TrkB mRNA in rat C6 glioma and type I astrocyte cultures. J Neurosci Res (1992) 0.85
Liposome-mediated NGF gene transfection following neuronal injury: potential therapeutic applications. Gene Ther (1999) 0.84
Apolipoprotein E allele 4 is not a sufficient or a necessary predictor of the development of Mild Cognitive Impairment. Eur Psychiatry (2009) 0.84
Immunolesion by 192IgG-saporin of rat basal forebrain cholinergic system: a useful tool to produce cortical cholinergic dysfunction. Prog Brain Res (1996) 0.84
Participation of active oxygen species in 6-hydroxydopamine toxicity to a human neuroblastoma cell line. Biochem Pharmacol (1982) 0.84
Nuclear factor kappaB/p49 is a negative regulatory factor in nerve growth factor-induced choline acetyltransferase promoter activity in PC12 cells. J Neurochem (2000) 0.83
Effects of nerve growth factor on glutathione peroxidase and catalase in PC12 cells. J Neurochem (1994) 0.83
Electron microscopic evidence for a cholinergic innervation of GABAergic parvalbumin-immunoreactive neurons in the rat medial septum. J Neurosci Res (1998) 0.83
Deafferentation of the septo-hippocampal pathway in rats as a model of the metabolic events in Alzheimer's disease. Int J Dev Neurosci (2001) 0.83
Stimulation of nerve growth factor receptors in PC12 by acetyl-L-carnitine. Biochem Pharmacol (1992) 0.83
Isolation of human nerve growth factor from placental tissue. Neurochem Res (1978) 0.83
Rat basal forebrain cholinergic lesion affects neuronal nitric oxide synthase activity in hippocampal and neocortical target regions. Brain Res (2001) 0.83
Effect of a long-term nerve growth factor treatment on body weight, blood pressure, and serum corticosterone in rats. Int J Dev Neurosci (1997) 0.82
Differential NF-kappa B regulation of bcl-x gene expression in hippocampus and basal forebrain in response to hypoxia. J Neurosci Res (2001) 0.82
DNA damage in astrocytes exposed to fumonisin B1. Neurochem Res (2002) 0.82
Allocation of perineuronal nets and parvalbumin-, calbindin-D28k- and glutamic acid decarboxylase-immunoreactivity in the amygdala of the rhesus monkey. Brain Res (1995) 0.82
Statistical approach to DNA chip analysis. Recent Prog Horm Res (2003) 0.82
Evidence for DNA fragmentation in the CNS of aged Fischer-344 rats. Neuroreport (1996) 0.82
Effect of methionine, glycine and serine on serine hydroxymethyltransferase activity in rat glioma and human neuroblastoma cells. J Neurosci Res (1980) 0.82
7S nerve growth factor protein in the golden hamster. J Neurochem (1976) 0.81
Modulation of APP processing and secretion by okadaic acid in primary guinea pig neurons. J Neural Transm (Vienna) (2000) 0.81
Potentiating and depressant effects of metabotropic glutamate receptor agonists on high-voltage-activated calcium currents in cultured retinal ganglion neurons from postnatal mice. Pflugers Arch (1994) 0.81
Amyloid precursor protein in guinea pigs--complete cDNA sequence and alternative splicing. Biochim Biophys Acta (1997) 0.81
Glutamate-stimulated secretion of amyloid precursor protein from cortical rat brain slices. Neurochem Int (1997) 0.81
Selective induction of c-Jun and NGF in reactive astrocytes after cholinergic degenerations in rat basal forebrain. Neuroreport (1997) 0.81
Prenatal alcohol exposure alters the development of sympathetic synaptic components and of nerve growth factor receptor expression selectivity in lymphoid organs. J Neurosci Res (1990) 0.81
Protein kinase Calpha and beta1 isoforms are regulators of alpha-secretory proteolytic processing of amyloid precursor protein in vivo. Eur J Neurosci (2001) 0.81
Effect of retinoic acid on nerve growth factor receptors. Cell Tissue Res (1987) 0.81
Monitoring blood flow alterations in the Tg2576 mouse model of Alzheimer's disease by in vivo magnetic resonance angiography at 17.6 T. Neuroimage (2011) 0.81
Free radical scavenger depletion in post-ischemic reperfusion brain damage. Neurochem Res (1993) 0.81
Postnatal laminar development of cholinergic receptors, protein kinase C and dihydropyridine-sensitive calcium antagonist binding in rat visual cortex. Effect of visual deprivation. Int J Dev Neurosci (1992) 0.80
Biodistribution and feasibility of non-viral IGF-I gene transfers in thermally injured skin. Lab Invest (2000) 0.80
Binding of nerve growth factor to its receptor. J Neurosci Res (1987) 0.80