Published in Infect Immun on November 01, 1998
Complete genome sequencing of Anaplasma marginale reveals that the surface is skewed to two superfamilies of outer membrane proteins. Proc Natl Acad Sci U S A (2004) 2.90
Emergence of Anaplasma marginale antigenic variants during persistent rickettsemia. Infect Immun (1999) 2.42
Antigens and alternatives for control of Anaplasma marginale infection in cattle. Clin Microbiol Rev (2003) 1.63
Identification of novel antigenic proteins in a complex Anaplasma marginale outer membrane immunogen by mass spectrometry and genomic mapping. Infect Immun (2005) 1.57
Differential expression and sequence conservation of the Anaplasma marginale msp2 gene superfamily outer membrane proteins. Infect Immun (2006) 1.39
The repertoire of Anaplasma marginale antigens recognized by CD4(+) T-lymphocyte clones from protectively immunized cattle is diverse and includes major surface protein 2 (MSP-2) and MSP-3. Infect Immun (1998) 1.37
Kinetics of antibody response to Ehrlichia canis immunoreactive proteins. Infect Immun (2003) 1.27
Surface-exposed proteins of Ehrlichia chaffeensis. Infect Immun (2007) 1.26
Expression of Anaplasma marginale major surface protein 2 operon-associated proteins during mammalian and arthropod infection. Infect Immun (2002) 1.25
Immunogenicity of Anaplasma marginale type IV secretion system proteins in a protective outer membrane vaccine. Infect Immun (2007) 1.17
Intrahaplotype and interhaplotype pairing of bovine leukocyte antigen DQA and DQB molecules generate functional DQ molecules important for priming CD4(+) T-lymphocyte responses. Immunogenetics (2005) 1.05
Anaplasma marginale type IV secretion system proteins VirB2, VirB7, VirB11, and VirD4 are immunogenic components of a protective bacterial membrane vaccine. Infect Immun (2010) 1.04
Identification of Anaplasma marginale outer membrane protein antigens conserved between A. marginale sensu stricto strains and the live A. marginale subsp. centrale vaccine. Infect Immun (2010) 0.98
CD4 T-cell epitopes associated with protective immunity induced following vaccination of mice with an ehrlichial variable outer membrane protein. Infect Immun (2007) 0.95
Genome-wide screening and identification of antigens for rickettsial vaccine development. FEMS Immunol Med Microbiol (2012) 0.95
Physical linkage of naturally complexed bacterial outer membrane proteins enhances immunogenicity. Infect Immun (2007) 0.94
Major histocompatibility complex class II DR-restricted memory CD4(+) T lymphocytes recognize conserved immunodominant epitopes of Anaplasma marginale major surface protein 1a. Infect Immun (2002) 0.94
Interleukin-12 as an adjuvant promotes immunoglobulin G and type 1 cytokine recall responses to major surface protein 2 of the ehrlichial pathogen Anaplasma marginale. Infect Immun (2000) 0.94
Expression of major surface protein 2 variants with conserved T-cell epitopes in Anaplasma centrale vaccinates. Infect Immun (2002) 0.92
DNA and a CpG oligonucleotide derived from Babesia bovis are mitogenic for bovine B cells. Infect Immun (1998) 0.89
Anaplasma marginale infection with persistent high-load bacteremia induces a dysfunctional memory CD4+ T lymphocyte response but sustained high IgG titers. Clin Vaccine Immunol (2010) 0.88
Rapid deletion of antigen-specific CD4+ T cells following infection represents a strategy of immune evasion and persistence for Anaplasma marginale. J Immunol (2008) 0.88
Mitogenic component in polar lipid-enriched Anaplasma phagocytophilum membranes. Clin Vaccine Immunol (2007) 0.88
Analysis of the Anaplasma marginale major surface protein 1 complex protein composition by tandem mass spectrometry. J Bacteriol (2006) 0.88
Association and evidence for linked recognition of type IV secretion system proteins VirB9-1, VirB9-2, and VirB10 in Anaplasma marginale. Infect Immun (2011) 0.87
Breadth of the CD4+ T cell response to Anaplasma marginale VirB9-1, VirB9-2 and VirB10 and MHC class II DR and DQ restriction elements. Immunogenetics (2012) 0.85
Protective immunity induced by immunization with a live, cultured Anaplasma marginale strain. Vaccine (2013) 0.84
The immunization-induced antibody response to the Anaplasma marginale major surface protein 2 and its association with protective immunity. Vaccine (2010) 0.84
CD4+ T lymphocytes from Anaplasma marginale major surface protein 2 (MSP2) vaccinees recognize naturally processed epitopes conserved in MSP3. Infect Immun (2004) 0.84
Linkage between Anaplasma marginale outer membrane proteins enhances immunogenicity but is not required for protection from challenge. Clin Vaccine Immunol (2013) 0.83
CD4 T cell antigens from Staphylococcus aureus Newman strain identified following immunization with heat-killed bacteria. Clin Vaccine Immunol (2012) 0.82
Identification of multilocus genetic heterogeneity in Anaplasma marginale subsp. centrale and its restriction following tick-borne transmission. Infect Immun (2013) 0.82
Subdominant antigens in bacterial vaccines: AM779 is subdominant in the Anaplasma marginale outer membrane vaccine but does not associate with protective immunity. PLoS One (2012) 0.82
Biased immunoglobulin G1 isotype responses induced in cattle with DNA expressing msp1a of Anaplasma marginale. Infect Immun (1999) 0.81
Adaptive immunity to Anaplasma pathogens and immune dysregulation: implications for bacterial persistence. Comp Immunol Microbiol Infect Dis (2012) 0.81
Knockout of an outer membrane protein operon of Anaplasma marginale by transposon mutagenesis. BMC Genomics (2014) 0.81
Subdominant Outer Membrane Antigens in Anaplasma marginale: Conservation, Antigenicity, and Protective Capacity Using Recombinant Protein. PLoS One (2015) 0.80
Epitope-based vaccines with the Anaplasma marginale MSP1a functional motif induce a balanced humoral and cellular immune response in mice. PLoS One (2013) 0.80
Long-term in vivo depletion of functional CD4+ T lymphocytes from calves requires both thymectomy and anti-CD4 monoclonal antibody treatment. Immunology (2001) 0.78
Cooperation of PD-1 and LAG-3 Contributes to T-Cell Exhaustion in Anaplasma marginale-Infected Cattle. Infect Immun (2016) 0.78
Immunogenicity of Outer Membrane Proteins VirB9-1 and VirB9-2, a Novel Nanovaccine against Anaplasma marginale. PLoS One (2016) 0.77
Immunogenicity of hypothetical highly conserved proteins as novel antigens in Anaplasma marginale. Curr Microbiol (2013) 0.76
Selective in vivo depletion of CD4(+) T lymphocytes with anti-CD4 monoclonal antibody during acute infection of calves with Anaplasma marginale. Clin Diagn Lab Immunol (2002) 0.76
Diversity of Ehrlichia ruminantium major antigenic protein 1-2 in field isolates and infected sheep. Infect Immun (2009) 0.76
Anaplasma marginale: Diversity, Virulence, and Vaccine Landscape through a Genomics Approach. Biomed Res Int (2016) 0.75
Identification of a T cell epitope that is globally conserved among outer membrane proteins (OMPs) OMP7, OMP8, and OMP9 of Anaplasma marginale strains and with OMP7 from the A. marginale subsp. centrale vaccine strain. Clin Vaccine Immunol (2016) 0.75
Nanoparticle-Based Delivery of Anaplasma marginale Membrane Proteins; VirB9-1 and VirB10 Produced in the Pichia pastoris Expression System. Nanomaterials (Basel) (2016) 0.75
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Common and isolate-restricted antigens of Anaplasma marginale detected with monoclonal antibodies. Infect Immun (1984) 3.31
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The immunoprotective Anaplasma marginale major surface protein 2 is encoded by a polymorphic multigene family. Infect Immun (1994) 2.82
Molecular basis for surface antigen size polymorphisms and conservation of a neutralization-sensitive epitope in Anaplasma marginale. Proc Natl Acad Sci U S A (1990) 2.74
Expression of Anaplasma marginale major surface protein 2 variants during persistent cyclic rickettsemia. Infect Immun (1998) 2.57
Immune serum against Anaplasma marginale initial bodies neutralizes infectivity for cattle. J Immunol (1984) 2.57
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Detection of cattle naturally infected with Anaplasma marginale in a region of endemicity by nested PCR and a competitive enzyme-linked immunosorbent assay using recombinant major surface protein 5. J Clin Microbiol (1998) 2.42
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Molecular size variations in an immunoprotective protein complex among isolates of Anaplasma marginale. Infect Immun (1988) 1.83
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Identification of Anaplasma marginale long-term carrier cattle by detection of serum antibody to isolated MSP-3. J Clin Microbiol (1991) 1.55
Phylogenetic relationship of Cowdria ruminantium, agent of heartwater, to Anaplasma marginale and other members of the order Rickettsiales determined on the basis of 16S rRNA sequence. Int J Syst Bacteriol (1992) 1.46
L-arginine-dependent killing of intracellular Ehrlichia risticii by macrophages treated with gamma interferon. Infect Immun (1992) 1.46
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Characterization of a neutralization-sensitive epitope on the Am 105 surface protein of Anaplasma marginale. Int J Parasitol (1987) 1.32
IFN-gamma stimulates IgG2 production from bovine B cells costimulated with anti-mu and mitogen. Cell Immunol (1994) 1.30
Detection of Anaplasma ovis infection in goats by major surface protein 5 competitive inhibition enzyme-linked immunosorbent assay. J Clin Microbiol (1995) 1.29
Putative adhesins of Anaplasma marginale: major surface polypeptides 1a and 1b. Infect Immun (1994) 1.28
The msp1 beta multigene family of Anaplasma marginale: nucleotide sequence analysis of an expressed copy. Infect Immun (1991) 1.28
Evaluation of Anaplasma marginale major surface protein 3 (MSP3) as a diagnostic test antigen. J Clin Microbiol (1996) 1.23
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Establishment and characterization of a T-cell line specific for Rickettsia tsutsugamushi. Infect Immun (1987) 1.12
Stimulation of nitric oxide production in macrophages by Babesia bovis. Infect Immun (1998) 1.09
CD4+ T-cell clones obtained from cattle chronically infected with Fasciola hepatica and specific for adult worm antigen express both unrestricted and Th2 cytokine profiles. Infect Immun (1994) 1.08
Bovine CD4(+) T-lymphocyte clones specific for rhoptry-associated protein 1 of Babesia bigemina stimulate enhanced immunoglobulin G1 (IgG1) and IgG2 synthesis. Infect Immun (1999) 1.02
Bovine helper T cell clones recognize five distinct epitopes on Babesia bovis merozoite antigens. Infect Immun (1992) 1.01
Efficacy of purified Anaplasma marginale initial bodies as a vaccine against anaplasmosis. Parasitol Res (1991) 0.97
Inducible L-arginine-dependent nitric oxide synthase activity in bovine bone marrow-derived macrophages. Biochem Biophys Res Commun (1994) 0.96
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Common and isolate-restricted antigens of Anaplasma marginale detected with monoclonal antibodies. Infect Immun (1984) 3.31
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Cyclic rickettsemia during persistent Anaplasma marginale infection of cattle. Infect Immun (1990) 2.64
Expression of Anaplasma marginale major surface protein 2 variants during persistent cyclic rickettsemia. Infect Immun (1998) 2.57
Immune serum against Anaplasma marginale initial bodies neutralizes infectivity for cattle. J Immunol (1984) 2.57
Immunization with an isolate-common surface protein protects cattle against anaplasmosis. Science (1986) 2.55
Emergence of Anaplasma marginale antigenic variants during persistent rickettsemia. Infect Immun (1999) 2.42
Detection of cattle naturally infected with Anaplasma marginale in a region of endemicity by nested PCR and a competitive enzyme-linked immunosorbent assay using recombinant major surface protein 5. J Clin Microbiol (1998) 2.42
Detection and quantitation of Anaplasma marginale in carrier cattle by using a nucleic acid probe. J Clin Microbiol (1989) 2.40
Impact of persistent Anaplasma marginale rickettsemia on tick infection and transmission. J Clin Microbiol (1993) 2.26
Immunization of cattle with a 36-kilodalton surface protein induces protection against homologous and heterologous Anaplasma marginale challenge. Infect Immun (1988) 2.23
Induction of protective immunity by using Anaplasma marginale initial body membranes. Infect Immun (1991) 2.20
Characterization of an immunoprotective protein complex of Anaplasma marginale by cloning and expression of the gene coding for polypeptide Am105L. Infect Immun (1987) 2.20
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Molecular size variations in an immunoprotective protein complex among isolates of Anaplasma marginale. Infect Immun (1988) 1.83
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