The P-glycoprotein efflux pump: how does it transport drugs?

On a biophysical and mathematical model of Pgp-mediated multidrug resistance: understanding the "space-time" dimension of MDR. Eur Biophys J (2009) 0.81

Fulvestrant reverses doxorubicin resistance in multidrug-resistant breast cell lines independent of estrogen receptor expression. Oncol Rep (2016) 0.75

Heteromer Nanostars by Spontaneous Self-Assembly. Nanomaterials (Basel) (2017) 0.75

The P-glycoprotein efflux pump: how does it transport drugs? J Membr Biol (1997) 2.03

Intracellular pH and the control of multidrug resistance. Proc Natl Acad Sci U S A (1994) 1.50

Uptake of antineoplastic agents into large unilamellar vesicles in response to a membrane potential. Biochim Biophys Acta (1985) 1.18

Are altered pHi and membrane potential in hu MDR 1 transfectants sufficient to cause MDR protein-mediated multidrug resistance? J Gen Physiol (1996) 1.16

Human MDR 1 protein overexpression delays the apoptotic cascade in Chinese hamster ovary fibroblasts. Biochemistry (1997) 1.08

Transfection of mu MDR 1 inhibits Na(+)-independent Cl-/-HCO3 exchange in Chinese hamster ovary cells. Biochemistry (1994) 1.06

Functional expression of P-glycoproteins in secretory vesicles. J Biol Chem (1994) 1.01

Doxorubicin resistance in P388 leukemia--evidence for reduced drug influx. Int J Cancer (1989) 1.00

Influence of phosphatidylserine on (Na+ + K+)-stimulated ATPase and acetylcholinesterase activities of dog brain synaptosomal plasma membranes. Biochem J (1984) 0.98

Biophysical aspects of P-glycoprotein-mediated multidrug resistance. Int Rev Cytol (1997) 0.97

Analysis of ion transport perturbations caused by hu MDR 1 protein overexpression. Biochemistry (1997) 0.84

Dissociation of phospholamban regulation of cardiac sarcoplasmic reticulum Ca2+ATPase by quercetin. J Biol Chem (1996) 0.83

The role of drug-lipid interactions in the biological activity of modulators of multi-drug resistance. Biochim Biophys Acta (1993) 0.83

Altered pHi regulation in 3T3/CFTR clones and their chemotherapeutic drug-selected derivatives. Am J Physiol (1997) 0.79

The TF1-ATPase and ATPase activities of assembled alpha 3 beta 3 gamma, alpha 3 beta 3 gamma delta, and alpha 3 beta 3 gamma epsilon complexes are stimulated by low and inhibited by high concentrations of rhodamine 6G whereas the dye only inhibits the alpha 3 beta 3, and alpha 3 beta 3 delta complexes. J Bioenerg Biomembr (1993) 0.79

Effects of membrane potential versus pHi on the cellular retention of doxorubicin analyzed via a comparison between cystic fibrosis transmembrane conductance regulator (CFTR) and multidrug resistance (MDR) transfectants. Biochem Pharmacol (1996) 0.75