Signaling through protein kinase C.

Essential function of TORC2 in PKC and Akt turn motif phosphorylation, maturation and signalling. EMBO J (2008) 4.79

Regulation of the ABC kinases by phosphorylation: protein kinase C as a paradigm. Biochem J (2003) 4.65

Regulation of novel protein kinase C epsilon by phosphorylation. Biochem J (2002) 1.65

Tyrosine phosphorylation of protein kinase Cdelta is essential for its apoptotic effect in response to etoposide. Mol Cell Biol (2002) 1.60

Structural requirements for localization and activation of protein kinase C mu (PKC mu) at the Golgi compartment. J Cell Biol (2002) 1.57

cPKC regulates interphase nuclear size during Xenopus development. J Cell Biol (2014) 1.50

Spatial and temporal regulation of protein kinase D (PKD). EMBO J (2000) 1.38

Atypical PKC-zeta regulates SDF-1-mediated migration and development of human CD34+ progenitor cells. J Clin Invest (2005) 1.36

Protein kinase D. A selective target for antigen receptors and a downstream target for protein kinase C in lymphocytes. J Exp Med (2000) 1.35

HCV-induced miR-21 contributes to evasion of host immune system by targeting MyD88 and IRAK1. PLoS Pathog (2013) 1.29

Phorbol 12-myristate 13-acetate induces epidermal growth factor receptor transactivation via protein kinase Cdelta/c-Src pathways in glioblastoma cells. J Biol Chem (2004) 1.28

GnRH signaling, the gonadotrope and endocrine control of fertility. Front Neuroendocrinol (2010) 1.23

Protein kinases and phosphatases in the control of cell fate. Enzyme Res (2011) 1.23

Mammalian diacylglycerol kinases: molecular interactions and biological functions of selected isoforms. Biochim Biophys Acta (2009) 1.17

Why target PIM1 for cancer diagnosis and treatment? Future Oncol (2010) 1.12

Diacylglycerol kinase epsilon is selective for both acyl chains of phosphatidic acid or diacylglycerol. J Biol Chem (2009) 1.10

Phosphatidylinositol 3-kinase/protein kinase Czeta-induced phosphorylation of Sp1 and p107 repressor release have a critical role in histone deacetylase inhibitor-mediated derepression [corrected] of transcription of the luteinizing hormone receptor gene. Mol Cell Biol (2006) 1.07

PKCdelta regulates cortical radial migration by stabilizing the Cdk5 activator p35. Proc Natl Acad Sci U S A (2009) 1.03

Regulation of smooth muscle by inducible nitric oxide synthase and NADPH oxidase in vascular proliferative diseases. Free Radic Biol Med (2008) 1.03

Disruption of Epstein-Barr virus latency in the absence of phosphorylation of ZEBRA by protein kinase C. J Virol (2002) 1.03

Role of atypical protein kinase C in estradiol-triggered G1/S progression of MCF-7 cells. Mol Cell Biol (2004) 1.02

A(1) adenosine receptor-mediated PKC and p42/p44 MAPK signaling in mouse coronary artery smooth muscle cells. Am J Physiol Heart Circ Physiol (2009) 0.99

PC phosphorylation increases the ability of AFAP-110 to cross-link actin filaments. Mol Biol Cell (2002) 0.99

Mapping of atypical protein kinase C within the nerve growth factor signaling cascade: relationship to differentiation and survival of PC12 cells. Mol Cell Biol (2000) 0.99

Long-term modulation of mitochondrial Ca2+ signals by protein kinase C isozymes. J Cell Biol (2004) 0.97

Protein kinase C inhibitors: rationale for use and potential in the treatment of bipolar disorder. CNS Drugs (2009) 0.97

Novel PKCeta is required to activate replicative functions of the major nonstructural protein NS1 of minute virus of mice. J Virol (2003) 0.96

Regulation of Ras signaling specificity by protein kinase C. Mol Cell Biol (2001) 0.95

h3/Acidic calponin: an actin-binding protein that controls extracellular signal-regulated kinase 1/2 activity in nonmuscle cells. Mol Biol Cell (2010) 0.94

Host gene targets for novel influenza therapies elucidated by high-throughput RNA interference screens. FASEB J (2012) 0.93

Influenza virus and cell signaling pathways. Med Sci Monit (2011) 0.93

Role of cPKCalpha and nPKCepsilon in EGF-stimulated goblet cell proliferation. Invest Ophthalmol Vis Sci (2008) 0.90

Gelsolin suppresses tumorigenicity through inhibiting PKC activation in a human lung cancer cell line, PC10. Br J Cancer (2003) 0.89

Etoposide induces protein kinase Cdelta- and caspase-3-dependent apoptosis in neuroblastoma cancer cells. Mol Pharmacol (2009) 0.88

Signal transduction pathways involved in proteolysis-inducing factor induced proteasome expression in murine myotubes. Br J Cancer (2003) 0.88

Novel cell death signaling pathways in neurotoxicity models of dopaminergic degeneration: relevance to oxidative stress and neuroinflammation in Parkinson's disease. Neurotoxicology (2009) 0.88

Proteins kinase Cɛ is required for non-small cell lung carcinoma growth and regulates the expression of apoptotic genes. Oncogene (2011) 0.87

Non-small cell lung carcinoma cell motility, rac activation and metastatic dissemination are mediated by protein kinase C epsilon. PLoS One (2012) 0.87

Amelioration of Murine Schistosoma mansoni Induced Liver Fibrosis by Mesenchymal Stem Cells. J Stem Cells Regen Med (2012) 0.86

Role of calcium-dependent protein kinases in chronic myeloid leukemia: combined effects of PKC and BCR-ABL signaling on cellular alterations during leukemia development. Onco Targets Ther (2014) 0.86

Differential recruitment of PKC isoforms in HeLa cells during redox stress. Cell Stress Chaperones (2007) 0.86

Protein kinase Czeta attenuates hypoxia-induced proliferation of fibroblasts by regulating MAP kinase phosphatase-1 expression. Mol Biol Cell (2006) 0.86

Differential effects of shear stress and cyclic strain on Sp1 phosphorylation by protein kinase Czeta modulates membrane type 1-matrix metalloproteinase in endothelial cells. Endothelium (2008) 0.83

Phosphatidylinositol 3-kinase/protein kinase Cdelta activation induces close homolog of adhesion molecule L1 (CHL1) expression in cultured astrocytes. Glia (2010) 0.81

Early phosphoinositide 3-kinase activity is required for late activation of protein kinase Cepsilon in platelet-derived-growth-factor-stimulated cells: evidence for signalling across a large temporal gap. Biochem J (2001) 0.80

Parkin-mediated ubiquitination regulates phospholipase C-gamma1. J Cell Mol Med (2008) 0.79

Deciphering the Arginine-binding preferences at the substrate-binding groove of Ser/Thr kinases by computational surface mapping. PLoS Comput Biol (2011) 0.78

The role of individual protein kinase C isoforms in mouse mast cell function and their targeting by the immunomodulatory parasitic worm product, ES-62. Immunol Lett (2015) 0.77

Diacylglycerol kinase regulation of protein kinase D during oxidative stress-induced intestinal cell injury. Biochem Biophys Res Commun (2008) 0.76

Human microRNAs profiling in response to influenza A viruses (subtypes pH1N1, H3N2, and H5N1). Exp Biol Med (Maywood) (2015) 0.76

Dopamine agonist signalling in the hypothalamus of female rats is independent of calcium-dependent kinases. J Neuroendocrinol (2009) 0.76

Protein kinase Czeta regulates phospholipase D activity in rat-1 fibroblasts expressing the alpha1A adrenergic receptor. BMC Cell Biol (2004) 0.75

ADAM17/EGFR axis promotes transglutaminase-dependent skin barrier formation through phosholipase C γ1 and protein kinase C pathways. Sci Rep (2016) 0.75

Protein Kinase C α Modulates Estrogen-Receptor-Dependent Transcription and Proliferation in Endometrial Cancer Cells. Obstet Gynecol Int (2013) 0.75