Published in Eur J Pharm Sci on July 01, 1998
Development of novel in silico model to predict corneal permeability for congeneric drugs: a QSPR approach. J Biomed Biotechnol (2011) 0.77
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Characterization of paracellular and aqueous penetration routes in cornea, conjunctiva, and sclera. Invest Ophthalmol Vis Sci (1997) 1.79
Microemulsions for topical delivery of estradiol. Int J Pharm (2003) 1.39
Despite substantial degradation, 2-arachidonoylglycerol is a potent full efficacy agonist mediating CB(1) receptor-dependent G-protein activation in rat cerebellar membranes. Br J Pharmacol (2001) 1.34
Cross-cultural music cognition: cognitive methodology applied to North Sami yoiks. Cognition (2000) 1.31
Interactions of polymeric and liposomal gene delivery systems with extracellular glycosaminoglycans: physicochemical and transfection studies. Biochim Biophys Acta (1999) 1.31
Effect of liposomal and free bisphosphonates on the IL-1 beta, IL-6 and TNF alpha secretion from RAW 264 cells in vitro. Pharm Res (1995) 1.29
Culture model of human corneal epithelium for prediction of ocular drug absorption. Invest Ophthalmol Vis Sci (2001) 1.24
Relation between myofibers and connective tissue during muscle injury repair. Scand J Med Sci Sports (2000) 1.22
Reliability of the tissue microarray based FISH for evaluation of the HER-2 oncogene in breast carcinoma. J Clin Pathol (2002) 1.22
Chemical enhancement of percutaneous absorption in relation to stratum corneum structural alterations. J Control Release (1999) 1.18
Comparison of cell proliferation and toxicity assays using two cationic liposomes. Pharm Res (1994) 1.13
Extracellular glycosaminoglycans modify cellular trafficking of lipoplexes and polyplexes. J Biol Chem (2001) 1.08
Piperazinylalkyl prodrugs of naproxen improve in vitro skin permeation. Eur J Pharm Sci (2000) 1.05
Targeting the cannabinoid CB2 receptor: mutations, modeling and development of CB2 selective ligands. Curr Med Chem (2005) 1.02
Interaction of liposomes with human skin in vitro--the influence of lipid composition and structure. Biochim Biophys Acta (1996) 0.98
Pharmacokinetic simulation of biowaiver criteria: the effects of gastric emptying, dissolution, absorption and elimination rates. Eur J Pharm Sci (2006) 0.96
Contrasting effects of alendronate and clodronate on RAW 264 macrophages: the role of a bisphosphonate metabolite. Eur J Pharm Sci (1999) 0.94
Dexmedetomidine-induced ocular hypotension in rabbits with normal or elevated intraocular pressures. Invest Ophthalmol Vis Sci (1992) 0.94
Evaluation of cytotoxicity of various ophthalmic drugs, eye drop excipients and cyclodextrins in an immortalized human corneal epithelial cell line. Pharm Res (1998) 0.93
Bisphosphonate prodrugs: synthesis and in vitro evaluation of novel acyloxyalkyl esters of clodronic acid. J Med Chem (1999) 0.93
Bisphosphonate prodrugs: synthesis and in vitro evaluation of novel clodronic acid dianhydrides as bioreversible prodrugs of clodronate. J Med Chem (1999) 0.93
Bisphosphonate prodrugs: synthesis and in vitro evaluation of alkyl and acyloxymethyl esters of etidronic acid as bioreversible prodrugs of etidronate. Eur J Pharm Sci (2000) 0.93
3D visualization and quantification of rat cortical bone porosity using a desktop micro-CT system: a case study in the tibia. J Microsc (2010) 0.92
Vitamin C enhances differentiation of a continuous keratinocyte cell line (REK) into epidermis with normal stratum corneum ultrastructure and functional permeability barrier. Histochem Cell Biol (2001) 0.92
Macrophage-like RAW 264 cell line and time-resolved fluoroimmunoassay (TRFIA) as tools in screening drug effects on cytokine secretion. Int J Immunopharmacol (1995) 0.90
Growth inhibition of macrophage-like and other cell types by liposome-encapsulated, calcium-bound, and free bisphosphonates in vitro. J Drug Target (1994) 0.90
Phospholipids affect stratum corneum lipid bilayer fluidity and drug partitioning into the bilayers. J Control Release (1999) 0.90
Liposome-skin interactions and their effects on the skin permeation of drugs. Eur J Pharm Sci (1999) 0.90
Oligonucleotide-cationic liposome interactions. A physicochemical study. Biochim Biophys Acta (1994) 0.89
Ophthalmic arachidonylethanolamide decreases intraocular pressure in normotensive rabbits. Curr Eye Res (1995) 0.89
A novel drug-regulated gene expression system based on the nuclear receptor constitutive androstane receptor (CAR). Pharm Res (2001) 0.89
Modified beta-cyclodextrin (SBE7-beta-CyD) with viscous vehicle improves the ocular delivery and tolerability of pilocarpine prodrug in rabbits. J Pharm Pharmacol (1996) 0.89
Placental glucose transporters in fetal intrauterine growth retardation and macrosomia. Gynecol Obstet Invest (1997) 0.88
A lipid carrier with a membrane active component and a small complex size are required for efficient cellular delivery of anti-sense phosphorothioate oligonucleotides. Eur J Pharm Sci (2000) 0.87
Effect of the CB1 receptor antagonist, SR141716A, on cannabinoid-induced ocular hypotension in normotensive rabbits. Life Sci (1998) 0.87
Co-administration of a water-soluble polymer increases the usefulness of cyclodextrins in solid oral dosage forms. Pharm Res (1998) 0.87
Effects of topical anandamides on intraocular pressure in normotensive rabbits. Life Sci (1996) 0.86
Accumulation of bisphosphonates in the aorta and some other tissues of healthy and atherosclerotic rabbits. J Lab Clin Med (1996) 0.86
Back and leg complaints in relation to muscle strength in young men. Scand J Rehabil Med (1980) 0.86
Improved ocular: systemic absorption ratio of timolol by viscous vehicle and phenylephrine. Invest Ophthalmol Vis Sci (1990) 0.84
Cationic liposomes improve stability and intracellular delivery of antisense oligonucleotides into CaSki cells. Biochim Biophys Acta (1994) 0.83
Roles of acid/base nature and molecular weight in drug release from matrices of gelfoam and monoisopropyl ester of poly(vinyl methyl ether-maleic anhydride). J Control Release (1998) 0.83
A comparison between iris-ciliary body concentration and receptor affinity of timolol. Acta Ophthalmol (Copenh) (1985) 0.83
Water-activated, pH-controlled patch in transdermal administration of timolol. II. Drug absorption and skin irritation. Eur J Pharm Sci (2000) 0.82
Level A in vitro-in vivo correlation (IVIVC) model with Bayesian approach to formulation series. J Pharm Sci (2006) 0.82
Formation of permeability barrier in epidermal organotypic culture for studies on drug transport. J Invest Dermatol (2001) 0.82
Controlled transdermal iontophoresis by ion-exchange fiber. J Control Release (2000) 0.82
Competitive inhibition of coumarin 7-hydroxylation by pilocarpine and its interaction with mouse CYP 2A5 and human CYP 2A6. Br J Pharmacol (1995) 0.82
Peptide-oligonucleotide phosphorothioate conjugates with membrane translocation and nuclear localization properties. Bioconjug Chem (1999) 0.81
Efficient adventitial gene delivery to rabbit carotid artery with cationic polymer-plasmid complexes. Gene Ther (1999) 0.81
Vascular density at the myotendinous junction of the rat gastrocnemius muscle after immobilization and remobilization. Am J Sports Med (1995) 0.81
Effects of immobilization and subsequent low- and high-intensity exercise on morphology of rat calf muscles. Scand J Med Sci Sports (1998) 0.81
Novel cationic amphiphilic 1,4-dihydropyridine derivatives for DNA delivery. Biochim Biophys Acta (2000) 0.80
Synthesis and in vitro evaluation of novel morpholinyl- and methylpiperazinylacyloxyalkyl prodrugs of 2-(6-methoxy-2-naphthyl)propionic acid (Naproxen) for topical drug delivery. J Med Chem (2000) 0.80
Hydroxypropyl-beta-cyclodextrin and its combination with hydroxypropyl-methylcellulose increases aqueous solubility of delta9-tetrahydrocannabinol. Life Sci (1998) 0.80
Hydroxypropyl-beta-cyclodextrin increases aqueous solubility and stability of anandamide. Life Sci (1996) 0.80
Effects of topical anandamide-transport inhibitors, AM404 and olvanil, on intraocular pressure in normotensive rabbits. Pharm Res (2001) 0.80
The single dose pharmacokinetics and safety of deramciclane in healthy male volunteers. Biopharm Drug Dispos (1999) 0.79
Effects of epinephrine pretreatment and solution pH on ocular and systemic absorption of ocularly applied timolol in rabbits. J Pharm Sci (1990) 0.79
Simultaneous determination of clodronate and its partial ester derivatives by ion-pair reversed-phase high-performance liquid chromatography coupled with evaporative light-scattering detection. J Chromatogr B Biomed Sci Appl (1997) 0.79
Clodronate (dichloromethylene bisphosphonate) inhibits LPS-stimulated IL-6 and TNF production by RAW 264 cells. Life Sci (1994) 0.79
In vitro evaluation of the effect of cyclodextrin complexation on pulmonary deposition of a peptide, cyclosporin A. Int J Pharm (2006) 0.79
Effects of calcium and lipophilicity on transport of clodronate and its esters through Caco-2 cells. Int J Pharm (2001) 0.79
Dodecyl N,N-dimethylamino acetate and azone enhance drug penetration across human, snake, and rabbit skin. Pharm Res (1991) 0.79
Pharmacokinetics and safety of deramciclane during multiple oral dosing. Int J Clin Pharmacol Ther (1999) 0.79
Determination of physicochemical properties, stability in aqueous solutions and serum hydrolysis of pilocarpic acid diesters. J Pharm Biomed Anal (1991) 0.78
Disposition of ophthalmic timolol in treated and untreated rabbit eyes. A multiple and single dose study. Exp Eye Res (1984) 0.78
Liquid chromatography determination of liposome components using a light-scattering evaporative detector. J Pharm Biomed Anal (1994) 0.78
Influence of lipids on the mannitol flux during transdermal iontophoresis in vitro. Eur J Pharm Sci (2000) 0.78
Hydroxypropyl-beta-cyclodextrin increases the aqueous solubility and stability of pilocarpine prodrugs. Pharm Res (1995) 0.78
Ocular absorption and irritation of pilocarpine prodrug is modified with buffer, polymer, and cyclodextrin in the eyedrop. Pharm Res (1995) 0.78
Comparison of enzymatic hydrolysis of pilocarpine prodrugs in human plasma, rabbit cornea, and butyrylcholinesterase solutions. J Pharm Sci (1995) 0.78
Increase in 3H-flunitrazepam binding in vitro and in vivo to rat brain benzodiazepine receptors by tofizopam, a 3,4-benzo-diazepine. Pharmacol Res Commun (1981) 0.78
Diminished dynamic performance capacity of back and abdominal muscles in concrete reinforcement workers. Scand J Work Environ Health (1978) 0.78
Cationic liposomes mediated delivery of antisense oligonucleotides targeted to HPV 16 E7 mRNA in CaSki cells. Antiviral Res (1994) 0.77
Enzymatic and permeation barrier of [D-Ala(2)]-Met-enkephalinamide in the anterior membranes of the albino rabbit eye. Eur J Pharm Sci (2000) 0.77
Gradient high-performance liquid chromatographic analysis of enkephalin peptides, their metabolites, and enzyme inhibitors using combined ultraviolet and electrochemical detection II. Application to ocular permeability studies in vitro. J Chromatogr B Biomed Sci Appl (1998) 0.77
Miotic effect and irritation potential of pilocarpine prodrug incorporated into a submicron emulsion vehicle. Int J Pharm (1999) 0.77
Effects of topical alpha-substituted anandamides on intraocular pressure in normotensive rabbits. Pharm Res (1997) 0.77
Complexation with tolbutamide modifies the physicochemical and tableting properties of hydroxypropyl-beta-cyclodextrin. Int J Pharm (2001) 0.76
Improved corneal pilocarpine permeability with O,O'-(1,4-xylylene) bispilocarpic acid ester double prodrugs. Pharm Res (1991) 0.76
Synthesis and in vitro evaluation of aminoacyloxyalkyl esters of 2-(6-methoxy-2-naphthyl)propionic acid as novel naproxen prodrugs for dermal drug delivery. Pharm Res (1999) 0.76
Cardiac effects of different eyedrop preparations of timolol in rabbits. Curr Eye Res (1992) 0.76
Two phases of ornithine decarboxylase activation during lymphocyte mitogenesis. Adv Exp Med Biol (1988) 0.76
The uptake of clodronate (dichloromethylene bisphosphonate) by macrophages in vivo and in vitro. Drug Metab Dispos (1990) 0.76
Transdermal delivery of levosimendan. Eur J Pharm Sci (2000) 0.75
In-situ crosslinkable thermo-responsive hydrogels for drug delivery. J Control Release (2006) 0.75
Synthesis and identification of pilocarpic acid diesters, prodrugs of pilocarpine. J Pharm Biomed Anal (1991) 0.75
Inhibitory properties of double-helix-forming circular oligonucleotides. Nucleic Acids Res (1997) 0.75
Water-activated, pH-controlled patch in transdermal administration of timolol. I. Preclinical tests. Eur J Pharm Sci (2000) 0.75