| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Neurochemical and behavioral effects of ciproxifan, a potent histamine H3-receptor antagonist.
|
J Pharmacol Exp Ther
|
1998
|
1.38
|
|
2
|
Synthesis and histamine H1 receptor agonist activity of a series of 2-phenylhistamines, 2-heteroarylhistamines, and analogues.
|
J Med Chem
|
1995
|
0.89
|
|
3
|
Influence of imidazole replacement in different structural classes of histamine H(3)-receptor antagonists.
|
Eur J Pharm Sci
|
2001
|
0.85
|
|
4
|
(Partial) agonist/antagonist properties of novel diarylalkyl carbamates on histamine H3 receptors.
|
Bioorg Med Chem
|
2000
|
0.84
|
|
5
|
Novel partial agonists for the histamine H(3) receptor with high in vitro and in vivo activity.
|
J Med Chem
|
1999
|
0.79
|
|
6
|
H2 receptor-mediated facilitation and H3 receptor-mediated inhibition of noradrenaline release in the guinea-pig brain.
|
Naunyn Schmiedebergs Arch Pharmacol
|
1998
|
0.79
|
|
7
|
Histaprodifen, methylhistaprodifen, and dimethylhistaprodifen are potent H1-receptor agonists in the pithed and in the anaesthetized rat.
|
Naunyn Schmiedebergs Arch Pharmacol
|
1999
|
0.77
|
|
8
|
The selective histamine H1-receptor agonist 2-(3-trifluoromethylphenyl)histamine increases waking in the rat.
|
Eur Neuropsychopharmacol
|
1994
|
0.77
|
|
9
|
Effects of iodoproxyfan, a potent and selective histamine H3 receptor antagonist, on alpha 2 and 5-HT3 receptors.
|
Inflamm Res
|
1995
|
0.77
|
|
10
|
Benzophenone derivatives and related compounds as potent histamine H3-receptor antagonists and potential PET/SPECT ligands.
|
Arch Pharm (Weinheim)
|
2001
|
0.77
|
|
11
|
Novel histaprodifen analogues as potent histamine H1-receptor agonists in the pithed and in the anaesthetized rat.
|
Naunyn Schmiedebergs Arch Pharmacol
|
2001
|
0.76
|
|
12
|
New histamine H(3)-receptor ligands of the proxifan series: imoproxifan and other selective antagonists with high oral in vivo potency.
|
J Med Chem
|
2000
|
0.76
|
|
13
|
Piperidine-containing histamine H3 receptor antagonists of the carbamate series: the influence of the additional ether functionality.
|
Pharmazie
|
2002
|
0.76
|
|
14
|
Synthesis and 5-HT2A antagonist activity of derivatives of the novel heterocycles indolo[3,2-d]pyrrolo[3,2-g]azecine and benzo[d]pyrrolo[3,2-g]azecine compared to the benz[d]indolo[2,3-g]azecine derivative LE 300.
|
Arch Pharm (Weinheim)
|
2001
|
0.76
|
|
15
|
Iodoaminopotentidine and related compounds: a new class of ligands with high affinity and selectivity for the histamine H2 receptor.
|
J Med Chem
|
1992
|
0.75
|
|
16
|
Histamine analogues. 36th communication. Basically substituted histamine derivatives with H1-agonistic activity.
|
Pharmazie
|
1992
|
0.75
|
|
17
|
Synthesis and autoradiographic evaluation of a novel high-affinity Tc-99m ligand for the 5-HT2A receptor.
|
Nucl Med Biol
|
1999
|
0.75
|
|
18
|
Piperidine-containing histamine H3-receptor antagonists of the carbamate series: variation of the spacer length.
|
Pharmazie
|
2001
|
0.75
|
|
19
|
[Synthesis and H2-agonistic activity of alkylsubstituted 3-(imidazole-4-yl) propylguanidine].
|
Arch Pharm (Weinheim)
|
1987
|
0.75
|
|
20
|
N alpha-alkylated derivatives of 2-phenylhistamines: synthesis and in vitro activity of potent histamine H1-receptor agonists.
|
Bioorg Med Chem Lett
|
1998
|
0.75
|
|
21
|
Piperidine-containing histamine H3 receptor antagonists of the carbamate series: the alkyl derivatives.
|
Pharmazie
|
2005
|
0.75
|
|
22
|
Unexpected partial H1-receptor agonism of imidazole-type histamine H3-receptor antagonists lacking a basic side chain.
|
Inflamm Res
|
2004
|
0.75
|
|
23
|
Lactones, XXY: Synthesis and 5-HT2-receptor affinity of some fluorophenylated alpha-aminomethyllactones.
|
Arch Pharm (Weinheim)
|
1993
|
0.75
|
|
24
|
Importance of the lipophilic group in carbamates having histamine H3-receptor antagonist activity.
|
Pharmazie
|
2000
|
0.75
|
|
25
|
Histamine analogues, XXXV: 2-substituted histamine derivatives containing classical moieties of H2-antagonists--a novel class of H1-agonists.
|
Arch Pharm (Weinheim)
|
1993
|
0.75
|
|
26
|
[7-fluoro-4-chromone-3-sulfur compounds].
|
Arch Pharm (Weinheim)
|
1994
|
0.75
|
|
27
|
[Quinazolinones. 1. Preparation, crystal structure and action of 2-methyl-3-(4-oxo-3-phenyl-thiazolidine-2-ylidenamino)-4-(3H)- quinazolinone].
|
Arch Pharm (Weinheim)
|
1984
|
0.75
|
|
28
|
In-vitro pharmacology of sarpogrelate and the enantiomers of its major metabolite: 5-HT2A receptor specificity, stereoselectivity and modulation of ritanserin-induced depression of 5-HT contractions in rat tail artery.
|
J Pharm Pharmacol
|
1995
|
0.75
|
|
29
|
The effect of lipophilic substituents on the H2-histaminergic activity of some close analogues of impromidine.
|
Arch Pharm (Weinheim)
|
1992
|
0.75
|