Published in Am J Respir Crit Care Med on November 01, 1998
An official ATS clinical practice guideline: interpretation of exhaled nitric oxide levels (FENO) for clinical applications. Am J Respir Crit Care Med (2011) 5.53
Relation of sputum inflammatory markers to symptoms and lung function changes in COPD exacerbations. Thorax (2000) 4.45
Canadian Thoracic Society recommendations for management of chronic obstructive pulmonary disease - 2007 update. Can Respir J (2007) 4.27
Exhaled nitric oxide measurements: clinical application and interpretation. Thorax (2006) 2.01
Blood eosinophils to direct corticosteroid treatment of exacerbations of chronic obstructive pulmonary disease: a randomized placebo-controlled trial. Am J Respir Crit Care Med (2012) 1.85
The role of CT scanning in multidimensional phenotyping of COPD. Chest (2011) 1.81
Sputum eosinophilia and the short term response to inhaled mometasone in chronic obstructive pulmonary disease. Thorax (2005) 1.81
Inflammatory cells in the airways in COPD. Thorax (2006) 1.79
Eosinophilic airway inflammation in COPD. Int J Chron Obstruct Pulmon Dis (2006) 1.61
The Asthma-COPD Overlap Syndrome: A Common Clinical Problem in the Elderly. J Allergy (Cairo) (2011) 1.49
Models of chronic obstructive pulmonary disease. Respir Res (2004) 1.42
Benralizumab for chronic obstructive pulmonary disease and sputum eosinophilia: a randomised, double-blind, placebo-controlled, phase 2a study. Lancet Respir Med (2014) 1.37
Eosinophilic bronchitis: clinical manifestations and implications for treatment. Thorax (2002) 1.19
Peripheral blood eosinophils: a surrogate marker for airway eosinophilia in stable COPD. Int J Chron Obstruct Pulmon Dis (2016) 1.03
Airways inflammation and treatment during acute exacerbations of COPD. Int J Chron Obstruct Pulmon Dis (2008) 1.00
Blood eosinophils and inhaled corticosteroid/long-acting β-2 agonist efficacy in COPD. Thorax (2015) 0.98
Predicting sputum eosinophilia in exacerbations of COPD using exhaled nitric oxide. Inflammation (2013) 0.96
Outcomes in COPD patients receiving tiotropium or salmeterol plus treatment with inhaled corticosteroids. Int J Chron Obstruct Pulmon Dis (2007) 0.95
Cough due to asthma and nonasthmatic eosinophilic bronchitis. Lung (2009) 0.95
Improvement of Airflow Limitation by Fluticasone Propionate/Salmeterol in Chronic Obstructive Pulmonary Disease: What is the Specific Marker? Front Pharmacol (2011) 0.94
Characterization of airway inflammation in patients with COPD using fractional exhaled nitric oxide levels: a pilot study. Int J Chron Obstruct Pulmon Dis (2014) 0.92
Factors influencing airway inflammation in chronic obstructive pulmonary disease. Thorax (2000) 0.92
Sputum inflammatory cell-based classification of patients with acute exacerbation of chronic obstructive pulmonary disease. PLoS One (2013) 0.89
Future therapeutic treatment of COPD: struggle between oxidants and cytokines. Int J Chron Obstruct Pulmon Dis (2007) 0.89
Glucocorticoid insensitivity as a future target of therapy for chronic obstructive pulmonary disease. Int J Chron Obstruct Pulmon Dis (2010) 0.88
Airways disease: phenotyping heterogeneity using measures of airway inflammation. Allergy Asthma Clin Immunol (2007) 0.87
Alcohol fixation of induced sputum samples for applications in rural communities. Can Respir J (2010) 0.86
Sputum analysis in diagnosis and management of obstructive airway diseases. Ther Clin Risk Manag (2005) 0.85
Inhaled corticosteroids in chronic obstructive pulmonary disease: a pro-con perspective. Br J Clin Pharmacol (2014) 0.84
Emerging pharmaceutical therapies for COPD. Int J Chron Obstruct Pulmon Dis (2017) 0.83
Steroid naive eosinophilic asthma: anti-inflammatory effects of fluticasone and montelukast. Thorax (2005) 0.82
Clinical features of eosinophilic bronchitis. Korean J Intern Med (2002) 0.82
Eosinophilic airway inflammation: role in asthma and chronic obstructive pulmonary disease. Ther Adv Chronic Dis (2016) 0.81
The efficiency of sputum cell counts in cystic fibrosis. Can Respir J (2007) 0.80
The use of sputum cell counts to evaluate asthma medications. Br J Clin Pharmacol (2001) 0.80
LAMA/LABA vs ICS/LABA in the treatment of COPD in Japan based on the disease phenotypes. Int J Chron Obstruct Pulmon Dis (2015) 0.79
Patterns of inflammation and the use of reversibility testing in smokers with airway complaints. BMC Pulm Med (2006) 0.79
Using fractional exhaled nitric oxide (FeNO) to diagnose steroid-responsive disease and guide asthma management in routine care. Clin Transl Allergy (2013) 0.78
Airway inflammation and mannitol challenge test in COPD. Respir Res (2011) 0.78
Sputum neutrophilia can mask eosinophilic bronchitis during exacerbations. Can Respir J (2007) 0.77
Inhaled steroids for COPD? Thorax (2001) 0.75
Effectiveness using higher inhaled corticosteroid dosage in patients with COPD by different blood eosinophilic counts. Int J Chron Obstruct Pulmon Dis (2016) 0.75
The Time Course of Pulmonary Function Tests in COPD Patients with Different Levels of Blood Eosinophils. Biomed Res Int (2016) 0.75
Bringing Stability to the Chronic Obstructive Pulmonary Disease Patient: Clinical and Pharmacological Considerations for Frequent Exacerbators. Drugs (2017) 0.75
Asthma-Chronic Obstructive Pulmonary Disease Overlap Syndrome: Nothing New Under the Sun. Immunol Allergy Clin North Am (2016) 0.75
The Value of Induced Sputum in the Diagnosis and Management of Children with Bronchial Asthma. Clujul Med (2014) 0.75
Effect of inhaled corticosteroids on blood eosinophil count in steroid-naïve patients with COPD. BMJ Open Respir Res (2016) 0.75
Clinical characteristics of eosinophilic COPD versus COPD patients with a history of asthma. Respir Res (2017) 0.75
The Relationship between Airway Inflammation and Exacerbation in Chronic Obstructive Pulmonary Disease. Tuberc Respir Dis (Seoul) (2017) 0.75
Bronchial reactivity to inhaled histamine: a method and clinical survey. Clin Allergy (1977) 14.37
Global strategy for asthma management and prevention: GINA executive summary. Eur Respir J (2008) 10.08
Indices of airway inflammation in induced sputum: reproducibility and validity of cell and fluid-phase measurements. Am J Respir Crit Care Med (1996) 5.69
Inhibitory effects of disodium cromoglycate on allergen-inhalation tests. Lancet (1968) 5.08
Reproducibility and comparison of responses to inhaled histamine and methacholine. Thorax (1978) 4.77
Bird breeder's (fancier's) lung. Lancet (1966) 4.68
Effect of encouragement on walking test performance. Thorax (1984) 4.44
Allergen-induced increase in non-allergic bronchial reactivity. Clin Allergy (1977) 4.42
Use of induced sputum cell counts to investigate airway inflammation in asthma. Thorax (1992) 4.30
The perception of breathlessness in asthma. Am Rev Respir Dis (1982) 4.17
The eosinophilic leukocyte: structure and function. Adv Immunol (1986) 4.08
Bronchial responsiveness to histamine or methacholine in asthma: measurement and clinical significance. J Allergy Clin Immunol (1981) 4.03
Mites and house-dust allergy. Lancet (1968) 4.01
The use of induced sputum to investigate airway inflammation. Thorax (1997) 3.85
Allergic reactions of the lungs to enzymes of Bacillus subtilis. Lancet (1969) 3.59
Non-eosinophilic asthma: importance and possible mechanisms. Thorax (2002) 3.53
Measurement of IgE in normal and allergic serum by radioimmunoassay. J Lab Clin Med (1971) 3.47
Establishment of an immature mast cell line from a patient with mast cell leukemia. Leuk Res (1988) 3.47
Eosinophils and mast cells in bronchoalveolar lavage in subjects with mild asthma. Relationship to bronchial hyperreactivity. Am Rev Respir Dis (1988) 3.45
Strategies of anti-cytokine monoclonal antibody development: immunoassay of IL-10 and IL-5 in clinical samples. Immunol Rev (1992) 3.42
The assessment and treatment of asthma: a conference report. J Allergy Clin Immunol (1990) 3.40
Cytotoxic properties of the eosinophil major basic protein. J Immunol (1979) 3.29
Determining asthma treatment by monitoring sputum cell counts: effect on exacerbations. Eur Respir J (2006) 3.09
Chronic cough: eosinophilic bronchitis without asthma. Lancet (1989) 3.07
Airway responsiveness to histamine and methacholine: relationship to minimum treatment to control symptoms of asthma. Thorax (1981) 3.06
An investigation of the cause of the eosinophilia-myalgia syndrome associated with tryptophan use. N Engl J Med (1990) 3.05
Allergen-induced increase in bronchial responsiveness to histamine: relationship to the late asthmatic response and change in airway caliber. J Allergy Clin Immunol (1982) 2.84
Sudden-onset fatal asthma. A distinct entity with few eosinophils and relatively more neutrophils in the airway submucosa? Am Rev Respir Dis (1993) 2.83
Reducing errors in the accident department: a simple method using radiographers. Br Med J (Clin Res Ed) (1985) 2.82
Damage to schistosomula of Schistosoma mansoni induced directly by eosinophil major basic protein. J Immunol (1979) 2.81
Hypoglycaemia precipitated by propranolol. Lancet (1966) 2.79
Standardization of inhalation provocation tests: two techniques of aerosol generation and inhalation compared. Am Rev Respir Dis (1981) 2.75
Cytotoxic effects of the guinea pig eosinophil major basic protein on tracheal epithelium. Lab Invest (1980) 2.70
3-(Phenylamino)alanine, a novel aniline-derived amino acid associated with the eosinophilia-myalgia syndrome: a link to the toxic oil syndrome? Mayo Clin Proc (1992) 2.64
The evaluation of a cell dispersion method of sputum examination. Clin Exp Allergy (1994) 2.58
Bronchial responsiveness to histamine: relationship to diurnal variation of peak flow rate, improvement after bronchodilator, and airway calibre. Thorax (1982) 2.53
Measurement of inflammatory indices in induced sputum: effects of selection of sputum to minimize salivary contamination. Eur Respir J (1996) 2.46
Acute asthma: emergency department management and prospective evaluation of outcome. CMAJ (1990) 2.45
Non-prescription use of bronchodilator aerosols. Med J Aust (1992) 2.41
The eosinophil and the pathophysiology of asthma. J Allergy Clin Immunol (1986) 2.29
Obesity in total hip replacement. J Bone Joint Surg Br (2008) 2.29
Diagnostic testing in chronic urticaria and angioedema. CMAJ (1992) 2.27
Effect of long-term treatment with an inhaled corticosteroid (budesonide) on airway hyperresponsiveness and clinical asthma in nonsteroid-dependent asthmatics. Am Rev Respir Dis (1990) 2.23
Identification by immunofluorescence of eosinophil granule major basic protein in lung tissues of patients with bronchial asthma. Lancet (1982) 2.21
The late phase of the immediate wheal and flare skin reaction. Its dependence upon IgE antibodies. J Clin Invest (1976) 2.19
Focused parathyroid surgery with intraoperative parathyroid hormone measurement as a day-case procedure. Br J Surg (2004) 2.17
Primary structure of the leukocyte function-associated molecule-1 alpha subunit: an integrin with an embedded domain defining a protein superfamily. J Cell Biol (1989) 2.14
Toxicity of eosinophil cationic proteins for guinea pig tracheal epithelium in vitro. Am Rev Respir Dis (1989) 2.08
The clinical spectrum of the eosinophilia-myalgia syndrome associated with L-tryptophan ingestion. Clinical features in 20 patients and aspects of pathophysiology. Ann Intern Med (1990) 2.06
Cardiac localization of eosinophil-granule major basic protein in acute necrotizing myocarditis. N Engl J Med (1990) 2.05
Late asthmatic responses. Am Rev Respir Dis (1987) 2.05
Protective effect of drugs on histamine-induced asthma. Thorax (1977) 2.02
Deposits of eosinophil granule proteins in cardiac tissues of patients with eosinophilic endomyocardial disease. Lancet (1987) 1.98
The radiological appearances in allergic broncho-pulmonary aspergillosis. Clin Radiol (1970) 1.97
Spontaneous and induced sputum to measure indices of airway inflammation in asthma. Am J Respir Crit Care Med (1996) 1.97
Late cutaneous allergic responses in isolated IgE-dependent reactions. J Allergy Clin Immunol (1973) 1.96
Comparative properties of the Charcot-Leyden crystal protein and the major basic protein from human eosinophils. J Clin Invest (1976) 1.96
Endogenous IL-10 protects mice from death during septic peritonitis. J Immunol (1995) 1.94
Nonvalidated food allergy tests. CMAJ (1988) 1.94
Induced sputum cell counts in healthy adults. Am J Respir Crit Care Med (2000) 1.93
The insulin-like growth factor (IGF)-dependent IGF binding protein-4 protease secreted by human fibroblasts is pregnancy-associated plasma protein-A. Proc Natl Acad Sci U S A (1999) 1.90
Identification of a major basic protein in guinea pig eosinophil granules. J Exp Med (1973) 1.87
Rapid calibration for 3-D freehand ultrasound. Ultrasound Med Biol (1998) 1.85
Purification of human eosinophil-derived neurotoxin. Proc Natl Acad Sci U S A (1981) 1.85
Elevated levels of the eosinophil granule major basic protein in the sputum of patients with bronchial asthma. Mayo Clin Proc (1981) 1.85
Prevalence of asthma, rhinitis and eczema among children in 2 Canadian cities: the International Study of Asthma and Allergies in Childhood. CMAJ (1999) 1.84
Molecular cloning of the human eosinophil peroxidase. Evidence for the existence of a peroxidase multigene family. J Exp Med (1989) 1.83
IgA-induced eosinophil degranulation. J Immunol (1989) 1.82
Candida albicans precipitins in respiratory disease in man. J Allergy (1968) 1.82
Association of the eosinophilia-myalgia syndrome with the ingestion of tryptophan. N Engl J Med (1990) 1.80
Canadian Thoracic Society guidelines for occupational asthma. Can Respir J (1998) 1.80
Dermal deposition of eosinophil-granule major basic protein in atopic dermatitis. Comparison with onchocerciasis. N Engl J Med (1985) 1.79
Eosinophilic myocarditis manifesting as myocardial infarction: early diagnosis and successful treatment. Mayo Clin Proc (1997) 1.78
Ultrasound screening for hip abnormalities: preliminary findings in 1001 neonates. Br Med J (Clin Res Ed) (1986) 1.78
Granulocyte/macrophage colony-stimulating factor and interleukin 3 release from human peripheral blood eosinophils and neutrophils. J Exp Med (1991) 1.77
Production of human immunoglobulin E antibody in vitro. J Immunol (1979) 1.73
Asthma and natural colds. Inflammatory indices in induced sputum: a feasibility study. Am J Respir Crit Care Med (1998) 1.72
The spectrum of IgE-mediated responses to latex. JAMA (1991) 1.71
Fatal reaction to peanut antigen in almond icing. CMAJ (1988) 1.70
Standardised methodology of sputum induction and processing. Eur Respir J Suppl (2002) 1.70