Roles for laminin in embryogenesis: exencephaly, syndactyly, and placentopathy in mice lacking the laminin alpha5 chain.

PubWeight™: 2.31‹?› | Rank: Top 2%

🔗 View Article (PMC 2132973)

Published in J Cell Biol on December 14, 1998

Authors

J H Miner1, J Cunningham, J R Sanes

Author Affiliations

1: Department of Medicine, Renal Division, St. Louis, Missouri, USA.

Articles citing this

Transduction of mechanical and cytoskeletal cues by YAP and TAZ. Nat Rev Mol Cell Biol (2012) 3.07

Beta1-integrin orients epithelial polarity via Rac1 and laminin. Mol Biol Cell (2004) 2.95

Perlecan maintains the integrity of cartilage and some basement membranes. J Cell Biol (1999) 2.94

FAK deficiency in cells contributing to the basal lamina results in cortical abnormalities resembling congenital muscular dystrophies. Neuron (2003) 2.86

The extracellular matrix in development and morphogenesis: a dynamic view. Dev Biol (2009) 2.82

Basement membranes: cell scaffoldings and signaling platforms. Cold Spring Harb Perspect Biol (2011) 2.73

Laminin polymerization induces a receptor-cytoskeleton network. J Cell Biol (1999) 2.36

SUMO-specific protease 2 is essential for modulating p53-Mdm2 in development of trophoblast stem cell niches and lineages. PLoS Biol (2008) 2.35

Lung organogenesis. Curr Top Dev Biol (2010) 2.30

Genetics and development of neural tube defects. J Pathol (2010) 2.10

Vascular development of the brain requires beta8 integrin expression in the neuroepithelium. J Neurosci (2005) 1.85

Deletion of the laminin alpha4 chain leads to impaired microvessel maturation. Mol Cell Biol (2002) 1.81

Maintenance of glomerular filtration barrier integrity requires laminin alpha5. J Am Soc Nephrol (2010) 1.73

Laminin: the crux of basement membrane assembly. J Cell Biol (2004) 1.69

Bridging structure with function: structural, regulatory, and developmental role of laminins. Int J Biochem Cell Biol (2007) 1.66

Coordinate control of axon defasciculation and myelination by laminin-2 and -8. J Cell Biol (2005) 1.56

Laminin-511 is an epithelial message promoting dermal papilla development and function during early hair morphogenesis. Genes Dev (2008) 1.41

Compound genetic ablation of nidogen 1 and 2 causes basement membrane defects and perinatal lethality in mice. Mol Cell Biol (2005) 1.40

Angiogenesis. Cold Spring Harb Perspect Biol (2011) 1.37

Integrin-linked kinase deletion from mouse cortex results in cortical lamination defects resembling cobblestone lissencephaly. J Neurosci (2005) 1.35

Laminins promote postsynaptic maturation by an autocrine mechanism at the neuromuscular junction. J Cell Biol (2008) 1.34

Laminin alpha5 is necessary for submandibular gland epithelial morphogenesis and influences FGFR expression through beta1 integrin signaling. Dev Biol (2007) 1.33

Regulation of radial glial survival by signals from the meninges. J Neurosci (2009) 1.30

A hypomorphic mutation in the mouse laminin alpha5 gene causes polycystic kidney disease. J Am Soc Nephrol (2006) 1.29

Mesangial cells organize the glomerular capillaries by adhering to the G domain of laminin alpha5 in the glomerular basement membrane. J Cell Biol (2003) 1.29

The fibulin-1 gene (FBLN1) is disrupted in a t(12;22) associated with a complex type of synpolydactyly. J Med Genet (2002) 1.26

The extracellular matrix and blood vessel formation: not just a scaffold. J Cell Mol Med (2007) 1.25

Distinct functions of glial and neuronal dystroglycan in the developing and adult mouse brain. J Neurosci (2010) 1.20

Endothelial cell-pericyte interactions stimulate basement membrane matrix assembly: influence on vascular tube remodeling, maturation, and stabilization. Microsc Microanal (2011) 1.20

Roles for genomic imprinting and the zygotic genome in placental development. Proc Natl Acad Sci U S A (2001) 1.19

Extracellular matrix and matrix receptors in blood-brain barrier formation and stroke. Dev Neurobiol (2011) 1.18

Laminin-10 is crucial for hair morphogenesis. EMBO J (2003) 1.17

The absence of nidogen 1 does not affect murine basement membrane formation. Mol Cell Biol (2000) 1.17

Gelatinase B (MMP-9) is not essential in the normal kidney and does not influence progression of renal disease in a mouse model of Alport syndrome. Am J Pathol (2000) 1.16

Order and disorder: the role of extracellular matrix in epithelial cancer. Cancer Invest (2002) 1.15

Defining the role of laminin-332 in carcinoma. Matrix Biol (2009) 1.14

Cell biology of embryonic migration. Birth Defects Res C Embryo Today (2008) 1.14

Laminin isoforms in endothelial and perivascular basement membranes. Cell Adh Migr (2012) 1.13

Gene structure and functional analysis of the mouse nidogen-2 gene: nidogen-2 is not essential for basement membrane formation in mice. Mol Cell Biol (2002) 1.12

Critical role of integrin-linked kinase in granule cell precursor proliferation and cerebellar development. J Neurosci (2006) 1.11

Role of extracellular matrix proteins and their receptors in the development of the vertebrate neuromuscular junction. Dev Neurobiol (2011) 1.10

Cortical deficiency of laminin gamma1 impairs the AKT/GSK-3beta signaling pathway and leads to defects in neurite outgrowth and neuronal migration. Dev Biol (2008) 1.08

Skeletal muscle laminin and MDC1A: pathogenesis and treatment strategies. Skelet Muscle (2011) 1.08

The C-terminal region of laminin beta chains modulates the integrin binding affinities of laminins. J Biol Chem (2009) 1.05

Opposing roles of integrin alpha6Abeta1 and dystroglycan in laminin-mediated extracellular signal-regulated kinase activation. Mol Biol Cell (2003) 1.05

Beta1 integrin and alpha-dystroglycan binding sites are localized to different laminin-G-domain-like (LG) modules within the laminin alpha5 chain G domain. Biochem J (2003) 1.04

Slc20a2 deficiency results in fetal growth restriction and placental calcification associated with thickened basement membranes and novel CD13 and lamininα1 expressing cells. Reprod Biol (2016) 1.03

Analysis of genes encoding laminin beta2 and related proteins in patients with Galloway-Mowat syndrome. Pediatr Nephrol (2008) 1.02

Protein composition and biomechanical properties of in vivo-derived basement membranes. Cell Adh Migr (2012) 1.02

Laminin alpha 5 influences the architecture of the mouse small intestine mucosa. J Cell Sci (2008) 0.99

Abl family tyrosine kinases are essential for basement membrane integrity and cortical lamination in the cerebellum. J Neurosci (2010) 0.97

Laminin-511: a multi-functional adhesion protein regulating cell migration, tumor invasion and metastasis. Cell Adh Migr (2012) 0.95

Epithelial-mesenchymal transition downregulates laminin alpha5 chain and upregulates laminin alpha4 chain in oral squamous carcinoma cells. Histochem Cell Biol (2008) 0.94

Integrin alpha5beta1 is necessary for regulation of radial migration of cortical neurons during mouse brain development. Eur J Neurosci (2010) 0.94

Laminin is required to orient epithelial polarity in the C. elegans pharynx. Development (2012) 0.93

Collagen VI ablation retards brain tumor progression due to deficits in assembly of the vascular basal lamina. Am J Pathol (2011) 0.93

The hippocampal laminin matrix is dynamic and critical for neuronal survival. Mol Biol Cell (2003) 0.92

Regulation of vascular integrity. J Mol Med (Berl) (2009) 0.92

Laminin-511 and integrin beta-1 in hair follicle development and basal cell carcinoma formation. BMC Dev Biol (2010) 0.88

Laminins affect T cell trafficking and allograft fate. J Clin Invest (2014) 0.88

An active role for basement membrane assembly and modification in tissue sculpting. J Cell Sci (2015) 0.87

Lung development in laminin gamma2 deficiency: abnormal tracheal hemidesmosomes with normal branching morphogenesis and epithelial differentiation. Respir Res (2006) 0.86

Epithelial fusion during neural tube morphogenesis. Birth Defects Res A Clin Mol Teratol (2012) 0.86

Extracellular matrix of secondary lymphoid organs impacts on B-cell fate and survival. Proc Natl Acad Sci U S A (2013) 0.86

Laminin α5 guides tissue patterning and organogenesis. Cell Adh Migr (2012) 0.86

Role of the podocyte (and glomerular endothelium) in building the GBM. Semin Nephrol (2012) 0.86

Microvesicles provide a mechanism for intercellular communication by embryonic stem cells during embryo implantation. Nat Commun (2016) 0.85

Role of JNK in network formation of human lung microvascular endothelial cells. Am J Physiol Lung Cell Mol Physiol (2008) 0.84

Chain-specific heparin-binding sequences in the laminin alpha chain LG45 modules. Biochemistry (2009) 0.81

Laminins: Roles and Utility in Wound Repair. Adv Wound Care (New Rochelle) (2015) 0.81

Regional differences in the expression of laminin isoforms during mouse neural tube development. Matrix Biol (2011) 0.80

Inhibition of transforming growth factor β worsens elastin degradation in a murine model of Kawasaki disease. Am J Pathol (2011) 0.80

A novel monoclonal antibody to human laminin α5 chain strongly inhibits integrin-mediated cell adhesion and migration on laminins 511 and 521. PLoS One (2013) 0.79

Functional consequences of cell type-restricted expression of laminin α5 in mouse placental labyrinth and kidney glomerular capillaries. PLoS One (2012) 0.79

The γ3 chain of laminin is widely but differentially expressed in murine basement membranes: expression and functional studies. Matrix Biol (2011) 0.79

Canonical Wnt signalling regulates epithelial patterning by modulating levels of laminins in zebrafish appendages. Development (2014) 0.78

Transgenic expression of human LAMA5 suppresses murine Lama5 mRNA and laminin α5 protein deposition. PLoS One (2011) 0.78

The bi-functional organization of human basement membranes. PLoS One (2013) 0.78

Abnormal Wnt and PI3Kinase signaling in the malformed intestine of lama5 deficient mice. PLoS One (2012) 0.77

Extracellular Matrix Components Regulate Cellular Polarity and Tissue Structure in the Developing and Mature Retina. J Ophthalmic Vis Res (2016) 0.76

Morphological and functional aspects of progenitors perturbed in cortical malformations. Front Cell Neurosci (2015) 0.76

Interdigital cell death in the embryonic limb is associated with depletion of Reelin in the extracellular matrix. Cell Death Dis (2013) 0.76

Differentiation of Human Embryonic Stem Cells to Endothelial Progenitor Cells on Laminins in Defined and Xeno-free Systems. Stem Cell Reports (2016) 0.76

The role of laminins in the organization and function of neuromuscular junctions. Matrix Biol (2016) 0.76

Neural tube closure: cellular, molecular and biomechanical mechanisms. Development (2017) 0.76

Basement Membranes in the Worm: A Dynamic Scaffolding that Instructs Cellular Behaviors and Shapes Tissues. Curr Top Membr (2015) 0.76

Cell-matrix signals specify bone endothelial cells during developmental osteogenesis. Nat Cell Biol (2017) 0.75

Collagen Type I Improves the Differentiation of Human Embryonic Stem Cells towards Definitive Endoderm. PLoS One (2015) 0.75

Laminin and type IV collagen isoform substitutions occur in temporally and spatially distinct patterns in developing kidney glomerular basement membranes. J Histochem Cytochem (2013) 0.75

Disruption of basal lamina components in neuromotor synapses of children with spastic quadriplegic cerebral palsy. PLoS One (2013) 0.75

Changes in Laminin Expression Pattern during Early Differentiation of Human Embryonic Stem Cells. PLoS One (2015) 0.75

Structural decoding of netrin-4 reveals a regulatory function towards mature basement membranes. Nat Commun (2016) 0.75

Requirement for basement membrane laminin α5 during urethral and external genital development. Mech Dev (2016) 0.75

Presynaptic congenital myasthenic syndrome with a homozygous sequence variant in LAMA5 combines myopia, facial tics, and failure of neuromuscular transmission. Am J Med Genet A (2017) 0.75

Articles cited by this

Derivation of completely cell culture-derived mice from early-passage embryonic stem cells. Proc Natl Acad Sci U S A (1993) 20.33

Neonatal lethality and lymphopenia in mice with a homozygous disruption of the c-abl proto-oncogene. Cell (1991) 14.23

Laminin--a glycoprotein from basement membranes. J Biol Chem (1979) 12.49

Implantation and the placenta: key pieces of the development puzzle. Science (1994) 4.75

Structure and biological activity of basement membrane proteins. Eur J Biochem (1989) 3.44

The laminin alpha chains: expression, developmental transitions, and chromosomal locations of alpha1-5, identification of heterotrimeric laminins 8-11, and cloning of a novel alpha3 isoform. J Cell Biol (1997) 3.34

Mutations in the laminin alpha 2-chain gene (LAMA2) cause merosin-deficient congenital muscular dystrophy. Nat Genet (1995) 3.05

Supramolecular assembly of basement membranes. Bioessays (1996) 2.97

Use of monospecific antisera and cRNA probes to localize the major changes in keratin expression during normal and abnormal epidermal differentiation. J Cell Biol (1988) 2.88

The roles of FGFs in the early development of vertebrate limbs. Genes Dev (1998) 2.86

Macromolecular organization of basement membranes. Curr Opin Cell Biol (1996) 2.72

Defects in limb, craniofacial, and thymic development in Jagged2 mutant mice. Genes Dev (1998) 2.70

Collagen COL4A3 knockout: a mouse model for autosomal Alport syndrome. Genes Dev (1996) 2.58

Properties of a basement membrane-related glycoprotein synthesized in culture by a mouse embryonal carcinoma-derived cell line. Cell (1979) 2.50

Aberrant differentiation of neuromuscular junctions in mice lacking s-laminin/laminin beta 2. Nature (1995) 2.47

The anchoring filament protein kalinin is synthesized and secreted as a high molecular weight precursor. J Biol Chem (1992) 2.36

The renal glomerulus of mice lacking s-laminin/laminin beta 2: nephrosis despite molecular compensation by laminin beta 1. Nat Genet (1995) 2.30

Molecular and functional defects in kidneys of mice lacking collagen alpha 3(IV): implications for Alport syndrome. J Cell Biol (1996) 2.29

Distribution and function of laminins in the neuromuscular system of developing, adult, and mutant mice. J Cell Biol (1997) 2.25

Murine muscular dystrophy caused by a mutation in the laminin alpha 2 (Lama2) gene. Nat Genet (1994) 2.19

Isoform switching of type IV collagen is developmentally arrested in X-linked Alport syndrome leading to increased susceptibility of renal basement membranes to endoproteolysis. J Clin Invest (1997) 2.03

A synaptic localization domain in the synaptic cleft protein laminin beta 2 (s-laminin) Science (1995) 1.72

Self-assembly of laminin isoforms. J Biol Chem (1997) 1.65

Mechanisms of neurulation: traditional viewpoint and recent advances. Development (1990) 1.64

Laminin receptors: achieving specificity through cooperation. Trends Cell Biol (1995) 1.62

A homozygous nonsense mutation in the beta 3 chain gene of laminin 5 (LAMB3) in Herlitz junctional epidermolysis bullosa. Genomics (1994) 1.59

Homeotic transformations in the mouse induced by overexpression of a human Hox3.3 transgene. Cell (1992) 1.58

Deficiency of merosin in dystrophic dy mice and genetic linkage of laminin M chain gene to dy locus. J Biol Chem (1994) 1.56

Molecular cloning of a novel laminin chain, alpha 5, and widespread expression in adult mouse tissues. J Biol Chem (1995) 1.55

Basal lamina assembly. Curr Opin Cell Biol (1994) 1.45

Developmental regulation of the laminin alpha5 chain suggests a role in epithelial and endothelial cell maturation. Dev Biol (1997) 1.39

Selective immunoreactivities of kidney basement membranes to monoclonal antibodies against laminin: localization of the end of the long arm and the short arms to discrete microdomains. J Cell Biol (1989) 1.36

Distribution of the alpha 1 and alpha 2 chains of collagen IV and of collagens V and VI in Alport syndrome. Kidney Int (1992) 1.30

Differential expression of five laminin alpha (1-5) chains in developing and adult mouse kidney. Dev Dyn (1997) 1.25

Synaptic laminin prevents glial entry into the synaptic cleft. Nature (1998) 1.22

Developmental expression of nicein adhesion protein (laminin-5) subunits suggests multiple morphogenic roles. Cell Adhes Commun (1994) 1.20

Differential expression of laminin A and B chains during development of embryonic mouse organs. Development (1990) 1.19

IAP insertion in the murine LamB3 gene results in junctional epidermolysis bullosa. Mamm Genome (1997) 1.17

Tissue-specific expression of the human laminin alpha5-chain, and mapping of the gene to human chromosome 20q13.2-13.3 and to distal mouse chromosome 2 near the locus for the ragged (Ra) mutation. FEBS Lett (1997) 0.98

Genetic landmarks for defects in mouse neural tube closure. Teratology (1997) 0.97

Developmental study of neural tube closure in a mouse stock with a high incidence of exencephaly. Teratology (1989) 0.95

Expression of laminin alpha 1, alpha 5 and beta 2 chains during embryogenesis of the kidney and vasculature. Matrix Biol (1996) 0.94

Inheritance and morphology of exencephaly, a neonatal lethal recessive with partial penetrance, in the house mouse. Genet Res (1978) 0.92

Distribution of the ten known laminin chains in the pathways and targets of developing sensory axons. J Comp Neurol (1997) 0.91

Epidermal ectoderm is required for full elevation and for convergence during bending of the avian neural plate. Dev Dyn (1997) 0.90

A homozygous nonsense mutation in the alpha 3 chain gene of laminin 5 (LAMA3) in Herlitz junctional epidermolysis bullosa: prenatal exclusion in a fetus at risk. Genomics (1995) 0.89

New Zealand white mice: an experimental model of exencephaly. Lab Anim Sci (1993) 0.84

Articles by these authors

(truncated to the top 100)

Imaging neuronal subsets in transgenic mice expressing multiple spectral variants of GFP. Neuron (2000) 22.02

Use of a recombinant retrovirus to study post-implantation cell lineage in mouse embryos. EMBO J (1986) 11.41

Definition, evaluation, and classification of renal osteodystrophy: a position statement from Kidney Disease: Improving Global Outcomes (KDIGO). Kidney Int (2006) 5.69

Defective neuromuscular synaptogenesis in agrin-deficient mutant mice. Cell (1996) 3.88

Skeletal and cardiac myopathies in mice lacking utrophin and dystrophin: a model for Duchenne muscular dystrophy. Cell (1997) 3.68

A human amphotropic retrovirus receptor is a second member of the gibbon ape leukemia virus receptor family. Proc Natl Acad Sci U S A (1994) 3.42

The laminin alpha chains: expression, developmental transitions, and chromosomal locations of alpha1-5, identification of heterotrimeric laminins 8-11, and cloning of a novel alpha3 isoform. J Cell Biol (1997) 3.34

Yield of serial sputum specimen examinations in the diagnosis of pulmonary tuberculosis: a systematic review. Int J Tuberc Lung Dis (2007) 3.25

Synaptic structure and development: the neuromuscular junction. Cell (1993) 3.17

Disturbance of cerebral function in people exposed to drinking water contaminated with aluminium sulphate: retrospective study of the Camelford water incident. BMJ (1999) 3.16

Failure of postsynaptic specialization to develop at neuromuscular junctions of rapsyn-deficient mice. Nature (1995) 3.10

Convection-enhanced delivery of AAV vector in parkinsonian monkeys; in vivo detection of gene expression and restoration of dopaminergic function using pro-drug approach. Exp Neurol (2000) 2.98

A laminin-like adhesive protein concentrated in the synaptic cleft of the neuromuscular junction. Nature (1989) 2.79

Dual requirement for gephyrin in glycine receptor clustering and molybdoenzyme activity. Science (1998) 2.79

Reinnervation of muscle fiber basal lamina after removal of myofibers. Differentiation of regenerating axons at original synaptic sites. J Cell Biol (1978) 2.78

Distinct roles of nerve and muscle in postsynaptic differentiation of the neuromuscular synapse. Nature (2001) 2.77

Roles for the integrin VLA-4 and its counter receptor VCAM-1 in myogenesis. Cell (1992) 2.67

Aberrant differentiation of neuromuscular junctions in mice lacking s-laminin/laminin beta 2. Nature (1995) 2.47

Disturbance of cerebral function by aluminium in haemodialysis patients without overt aluminium toxicity. Lancet (1989) 2.47

Syne-1, a dystrophin- and Klarsicht-related protein associated with synaptic nuclei at the neuromuscular junction. J Biol Chem (2000) 2.46

Progressive muscular dystrophy in alpha-sarcoglycan-deficient mice. J Cell Biol (1998) 2.44

Mammalian muscle cells bear a cell-autonomous, heritable memory of their rostrocaudal position. Cell (1992) 2.44

The encephalomyocarditis virus internal ribosome entry site allows efficient coexpression of two genes from a recombinant provirus in cultured cells and in embryos. Mol Cell Biol (1991) 2.42

Concentration of acetylcholine receptor mRNA in synaptic regions of adult muscle fibres. Nature (1985) 2.35

The renal glomerulus of mice lacking s-laminin/laminin beta 2: nephrosis despite molecular compensation by laminin beta 1. Nat Genet (1995) 2.30

Molecular and functional defects in kidneys of mice lacking collagen alpha 3(IV): implications for Alport syndrome. J Cell Biol (1996) 2.29

Distribution and function of laminins in the neuromuscular system of developing, adult, and mutant mice. J Cell Biol (1997) 2.25

Collagen IV alpha 3, alpha 4, and alpha 5 chains in rodent basal laminae: sequence, distribution, association with laminins, and developmental switches. J Cell Biol (1994) 2.24

Cholinesterase is associated with the basal lamina at the neuromuscular junction. Nature (1978) 2.18

Health effects of acid aerosols on North American children: respiratory symptoms. Environ Health Perspect (1996) 2.17

Increased erythropoietin requirements in patients with failed renal transplants returning to a dialysis programme. Nephrol Dial Transplant (1994) 2.16

Laminin, fibronectin, and collagen in synaptic and extrasynaptic portions of muscle fiber basement membrane. J Cell Biol (1982) 2.10

Teaching and assessing ethics and law in the dental curriculum. Br Dent J (1999) 2.09

Expression of several adhesive macromolecules (N-CAM, L1, J1, NILE, uvomorulin, laminin, fibronectin, and a heparan sulfate proteoglycan) in embryonic, adult, and denervated adult skeletal muscle. J Cell Biol (1986) 2.07

Pamidronate therapy as prevention of bone loss following renal transplantation. Kidney Int (2000) 2.06

Maturation and maintenance of the neuromuscular synapse: genetic evidence for roles of the dystrophin--glycoprotein complex. Neuron (2000) 2.04

Distribution and isolation of four laminin variants; tissue restricted distribution of heterotrimers assembled from five different subunits. Cell Regul (1990) 2.02

Role for alpha-dystrobrevin in the pathogenesis of dystrophin-dependent muscular dystrophies. Nat Cell Biol (1999) 2.01

Three mouse models of muscular dystrophy: the natural history of strength and fatigue in dystrophin-, dystrophin/utrophin-, and laminin alpha2-deficient mice. Neuromuscul Disord (2001) 1.97

A multicenter review of the treatment of major truncal necrotizing infections with and without hyperbaric oxygen therapy. Am J Surg (1994) 1.92

Asynchronous synapse elimination in neonatal motor units: studies using GFP transgenic mice. Neuron (2001) 1.91

Distribution of N-CAM in synaptic and extrasynaptic portions of developing and adult skeletal muscle. J Cell Biol (1986) 1.83

Mice deficient for the secreted glycoprotein SPARC/osteonectin/BM40 develop normally but show severe age-onset cataract formation and disruption of the lens. EMBO J (1998) 1.83

Cell lineage in the cerebral cortex of the mouse studied in vivo and in vitro with a recombinant retrovirus. Neuron (1988) 1.81

Climate change and the integrity of science. Science (2010) 1.80

Neural cell adhesion molecule (N-CAM) accumulates in denervated and paralyzed skeletal muscles. Proc Natl Acad Sci U S A (1985) 1.79

Molecular forms of N-CAM and its RNA in developing and denervated skeletal muscle. J Cell Biol (1986) 1.79

Antibodies that bind specifically to synaptic sites on muscle fiber basal lamina. J Cell Biol (1979) 1.75

A synaptic localization domain in the synaptic cleft protein laminin beta 2 (s-laminin) Science (1995) 1.72

Lamina-specific connectivity in the brain: regulation by N-cadherin, neurotrophins, and glycoconjugates. Science (1997) 1.69

Development. The decade of the developing brain. Curr Opin Neurobiol (2000) 1.65

Cancer in Indigenous Australians: a review. Cancer Causes Control (2003) 1.64

Denervation supersensitivity in skeletal muscle: analysis with a cloned cDNA probe. J Cell Biol (1984) 1.62

Alternatively spliced isoforms of nerve- and muscle-derived agrin: their roles at the neuromuscular junction. Neuron (1999) 1.60

Regional variation in the incidence of end-stage renal disease in Indigenous Australians. Med J Aust (2001) 1.56

Vasospastic elements in myocardial infarction following coronary occlusion in the dog. Cardiovasc Res (1968) 1.55

Molecular cloning of a novel laminin chain, alpha 5, and widespread expression in adult mouse tissues. J Biol Chem (1995) 1.55

Rapid dendritic remodeling in the developing retina: dependence on neurotransmission and reciprocal regulation by Rac and Rho. J Neurosci (2000) 1.55

Consequences of neural asynchrony: a case of auditory neuropathy. J Assoc Res Otolaryngol (2000) 1.55

Distinct domains of MuSK mediate its abilities to induce and to associate with postsynaptic specializations. J Cell Biol (1999) 1.54

Agrin isoforms with distinct amino termini: differential expression, localization, and function. J Cell Biol (2000) 1.50

A knock-in mouse model reveals roles for nuclear Apc in cell proliferation, Wnt signal inhibition and tumor suppression. Oncogene (2011) 1.49

Biliopleural fistula as a complication of percutaneous biliary drainage: experimental evidence for pleural inflammation. Am Rev Respir Dis (1988) 1.48

Mutation detection by highly sensitive methods indicates that p53 gene mutations in breast cancer can have important prognostic value. Proc Natl Acad Sci U S A (1996) 1.45

Rapsyn is required for MuSK signaling and recruits synaptic components to a MuSK-containing scaffold. Neuron (1997) 1.45

Rhodococcus equi in CAPD-associated peritonitis treated with azithromycin. Nephrol Dial Transplant (1996) 1.44

Differential membrane localization and intermolecular associations of alpha-dystrobrevin isoforms in skeletal muscle. J Cell Biol (1998) 1.44

Increased use of pre-operative imaging and laparoscopy has no impact on clinical outcomes in patients undergoing appendicectomy. Ann R Coll Surg Engl (2011) 1.44

Pancreatic sphincter hypertension increases the risk of post-ERCP pancreatitis. Endoscopy (1997) 1.44

High-dose calcium carbonate with stepwise reduction in dialysate calcium concentration: effective phosphate control and aluminium avoidance in haemodialysis patients. Nephrol Dial Transplant (1989) 1.43

Hand-held portable sonography for the on-mountain exclusion of a pneumothorax. Wilderness Environ Med (2001) 1.43

Perineurium originates from fibroblasts: demonstration in vitro with a retroviral marker. Science (1989) 1.41

Maturation of the acetylcholine receptor in skeletal muscle: regulation of the AChR gamma-to-epsilon switch. Dev Biol (1996) 1.41

Twenty year comparison of a Bjork-Shiley mechanical heart valve with porcine bioprostheses. Heart (2003) 1.39

How important is vitamin D deficiency in uraemia? Nephrol Dial Transplant (1997) 1.39

Partial characterization of the Purkinje cell antigens in paraneoplastic cerebellar degeneration. Neurology (1986) 1.39

Reinnervation of original synaptic sites on muscle fiber basement membrane after disruption of the muscle cells. Proc Natl Acad Sci U S A (1977) 1.38

Treatment of erythropoietin resistance with cyclosporin. Lancet (1994) 1.38

Antibody-dependent cellular cytotoxicity of human vascular endothelium in systemic sclerosis. Clin Exp Immunol (1984) 1.37

Properly formed but improperly localized synaptic specializations in the absence of laminin alpha4. Nat Neurosci (2001) 1.37

Subtle neuromuscular defects in utrophin-deficient mice. J Cell Biol (1997) 1.37

Erythroid Kruppel-like factor (EKLF) coordinates erythroid cell proliferation and hemoglobinization in cell lines derived from EKLF null mice. Blood (2001) 1.34

Neurons and glia arise from a common progenitor in chicken optic tectum: demonstration with two retroviruses and cell type-specific antibodies. Proc Natl Acad Sci U S A (1990) 1.34

Fibroblasts that proliferate near denervated synaptic sites in skeletal muscle synthesize the adhesive molecules tenascin(J1), N-CAM, fibronectin, and a heparan sulfate proteoglycan. J Cell Biol (1989) 1.33

Genetic analysis of collagen Q: roles in acetylcholinesterase and butyrylcholinesterase assembly and in synaptic structure and function. J Cell Biol (1999) 1.33

Coexpression of factor VIII heavy and light chain adeno-associated viral vectors produces biologically active protein. Proc Natl Acad Sci U S A (1999) 1.32

Functional effect of adeno-associated virus mediated gene transfer of aromatic L-amino acid decarboxylase into the striatum of 6-OHDA-lesioned rats. Mol Ther (2001) 1.31

The basal lamina of the neuromuscular junction. Cold Spring Harb Symp Quant Biol (1983) 1.30

Synapse-associated expression of an acetylcholine receptor-inducing protein, ARIA/heregulin, and its putative receptors, ErbB2 and ErbB3, in developing mammalian muscle. Dev Biol (1995) 1.27

Lamina-specific expression of adhesion molecules in developing chick optic tectum. J Neurosci (1995) 1.27

Synaptic integrins in developing, adult, and mutant muscle: selective association of alpha1, alpha7A, and alpha7B integrins with the neuromuscular junction. Dev Biol (1996) 1.27

Convection-enhanced delivery of AAV-2 combined with heparin increases TK gene transfer in the rat brain. Neuroreport (2001) 1.26

Self-assessed health among indigenous Australians: how valid is a global question? Am J Public Health (2001) 1.25

Migratory paths of neurons and glia in the embryonic chick spinal cord. J Neurosci (1995) 1.25

Primary sequence of a motor neuron-selective adhesive site in the synaptic basal lamina protein S-laminin. Cell (1989) 1.24

The functions of laminins: lessons from in vivo studies. Matrix Biol (1996) 1.23

Development of basal lamina in synaptic and extrasynaptic portions of embryonic rat muscle. Dev Biol (1984) 1.23

Developmentally regulated spontaneous activity in the embryonic chick retina. J Neurosci (1998) 1.23

Characterization of Salmonella associated with pig ear dog treats in Canada. J Clin Microbiol (2001) 1.23

Cyclic nucleotide-dependent protein kinases. V. Preparation and properties of adenosine 3',5'-monophosphate-dependent protein kinase from various bovine tissues. Biochim Biophys Acta (1970) 1.23