Primary Operation in SYnchronous meTastasized InVasivE Breast Cancer (POSYTIVE)

Clinical Trial ID NCT01015625

PubWeight™ 2.52‹?›

🔗 Visit the ClinicalTrials.gov page for NCT01015625

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Prospective identification of tumorigenic breast cancer cells. Proc Natl Acad Sci U S A 2003 59.17
2 Glioma stem cells promote radioresistance by preferential activation of the DNA damage response. Nature 2006 27.91
3 Effects of radiotherapy and of differences in the extent of surgery for early breast cancer on local recurrence and 15-year survival: an overview of the randomised trials. Lancet 2005 24.57
4 Twenty-year follow-up of a randomized trial comparing total mastectomy, lumpectomy, and lumpectomy plus irradiation for the treatment of invasive breast cancer. N Engl J Med 2002 18.61
5 Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo. Nature 1993 15.70
6 Twenty-year follow-up of a randomized study comparing breast-conserving surgery with radical mastectomy for early breast cancer. N Engl J Med 2002 12.83
7 Nephrectomy followed by interferon alfa-2b compared with interferon alfa-2b alone for metastatic renal-cell cancer. N Engl J Med 2001 11.73
8 Radical nephrectomy plus interferon-alfa-based immunotherapy compared with interferon alfa alone in metastatic renal-cell carcinoma: a randomised trial. Lancet 2001 6.24
9 Self-renewal and solid tumor stem cells. Oncogene 2004 4.60
10 Complete excision of primary breast tumor improves survival of patients with metastatic breast cancer at diagnosis. J Clin Oncol 2006 3.77
11 Lifetime exposure to a soluble TGF-beta antagonist protects mice against metastasis without adverse side effects. J Clin Invest 2002 3.24
12 Is cancer a disease of self-seeding? Nat Med 2006 3.19
13 TGF-beta switches from tumor suppressor to prometastatic factor in a model of breast cancer progression. J Clin Invest 2003 3.01
14 Effect of primary tumor extirpation in breast cancer patients who present with stage IV disease and an intact primary tumor. Ann Surg Oncol 2006 2.84
15 Surgical removal of the primary tumor increases overall survival in patients with metastatic breast cancer: analysis of the 1988-2003 SEER data. Ann Surg Oncol 2007 2.36
16 Does aggressive local therapy improve survival in metastatic breast cancer? Surgery 2002 2.13
17 Correlation of vascular endothelial growth factor content with recurrences, survival, and first relapse site in primary node-positive breast carcinoma after adjuvant treatment. J Clin Oncol 2000 1.68
18 Morbidity and mortality following breast cancer surgery in women: national benchmarks for standards of care. Ann Surg 2007 1.57
19 Elevated plasma transforming growth factor-beta 1 levels in breast cancer patients decrease after surgical removal of the tumor. Ann Surg 1995 1.40
20 Interleukin-2 based immunotherapy for metastatic renal cell carcinoma with the kidney in place. J Urol 1999 1.07
21 Does local surgery have a role in the management of stage IV breast cancer? Eur J Surg Oncol 2003 1.05
22 Preoperative core needle biopsy does not increase local recurrence rate in breast cancer patients. Breast Cancer Res Treat 2006 1.03
23 A phase II study of interferon-alpha, interleukin-2 and 5-fluorouracil in advanced renal carcinoma: clinical data and laboratory evidence of protease activation. Br J Urol 1996 0.96
24 Prognostic correlation of basic fibroblast growth factor and vascular endothelial growth factor in 1307 primary breast cancers. Clin Breast Cancer 2003 0.95
25 Higher plasma vascular endothelial growth factor levels correlate with menopause, overexpression of p53, and recurrence of breast cancer. Breast Cancer 2003 0.90
26 Primary metastatic breast cancer: the impact of locoregional therapy. Breast Care (Basel) 2014 0.88
27 Changes in plasma vascular endothelial growth factor, angiopoietins, and their receptors following surgery for breast cancer. Cancer Lett 2006 0.86
28 Does removal of the primary tumor in metastatic breast cancer improve survival? J Womens Health (Larchmt) 2013 0.86
29 Systemic effects of surgery: quantitative analysis of circulating basic fibroblast growth factor (bFGF), Vascular endothelial growth factor (VEGF) and transforming growth factor beta (TGF-beta) in patients with breast cancer who underwent limited or extended surgery. Breast Cancer Res Treat 2005 0.82
30 Resection of the primary tumor in stage IV breast cancer. World J Clin Oncol 2014 0.78
31 Plasma vascular endothelial growth factor is useful in assessing progression of breast cancer post surgery and during adjuvant treatment. Int J Oncol 2002 0.78
32 Changes in the circulating plasma levels of VEGF and VEGF-D after adjuvant chemotherapy in patients with breast cancer and 1 to 3 positive lymph nodes. Anticancer Res 2006 0.77
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