A Phase 1/2 Randomized, Blinded, Placebo Controlled Study of Ipilimumab in Combination With INCB024360 or Placebo in Subjects With Unresectable or Metastatic Melanoma

Clinical Trial ID NCT01604889

PubWeight™ 23.87‹?›

🔗 Visit the ClinicalTrials.gov page for NCT01604889

Top papers

Rank Title Journal Year PubWeight™‹?›
1 At the bedside: CTLA-4- and PD-1-blocking antibodies in cancer immunotherapy. J Leukoc Biol 2013 1.90
2 CTLA-4 blockade in tumor models: an overview of preclinical and translational research. Cancer Immun 2013 1.71
3 Pathways and therapeutic targets in melanoma. Oncotarget 2014 1.17
4 Molecular Pathways: Targeting IDO1 and Other Tryptophan Dioxygenases for Cancer Immunotherapy. Clin Cancer Res 2015 1.09
5 Trial watch: IDO inhibitors in cancer therapy. Oncoimmunology 2014 1.01
6 IDO in the Tumor Microenvironment: Inflammation, Counter-Regulation, and Tolerance. Trends Immunol 2016 0.96
7 Rational combinations of immunotherapeutics that target discrete pathways. J Immunother Cancer 2013 0.95
8 Checkpoint modulation in melanoma: an update on ipilimumab and future directions. Curr Oncol Rep 2013 0.94
9 Immune checkpoint blockade in cancer treatment: a double-edged sword cross-targeting the host as an "innocent bystander". Toxins (Basel) 2014 0.92
10 T and NK cells: two sides of tumor immunoevasion. J Transl Med 2013 0.89
11 Immune escape mechanisms as a guide for cancer immunotherapy. Clin Cancer Res 2014 0.88
12 Tumor antigen-targeting monoclonal antibody-based immunotherapy: Orchestrating combined strategies for the development of long-term antitumor immunity. Oncoimmunology 2014 0.87
13 Small molecule drugs with immunomodulatory effects in cancer. Hum Vaccin Immunother 2015 0.86
14 The past, present and future of immunotherapy against tumor. Transl Lung Cancer Res 2015 0.85
15 Trial Watch-Small molecules targeting the immunological tumor microenvironment for cancer therapy. Oncoimmunology 2016 0.84
16 O-alkylhydroxylamines as rationally-designed mechanism-based inhibitors of indoleamine 2,3-dioxygenase-1. Eur J Med Chem 2015 0.84
17 Targeting the indoleamine 2,3-dioxygenase pathway in cancer. J Immunother Cancer 2015 0.84
18 Dendritic cell vaccination, immune regulation, and clinical outcomes in ovarian cancer. Front Immunol 2013 0.82
19 Early Carcinogenesis Involves the Establishment of Immune Privilege via Intrinsic and Extrinsic Regulation of Indoleamine 2,3-dioxygenase-1: Translational Implications in Cancer Immunotherapy. Front Immunol 2014 0.80
20 Inflammation Models of Depression in Rodents: Relevance to Psychotropic Drug Discovery. Int J Neuropsychopharmacol 2016 0.78
21 Synthesis of [(18) F] 4-amino-N-(3-chloro-4-fluorophenyl)-N'-hydroxy-1,2,5-oxadiazole-3-carboximidamide (IDO5L): a novel potential PET probe for imaging of IDO1 expression. J Labelled Comp Radiopharm 2015 0.78
22 Tryptophan PET Imaging of the Kynurenine Pathway in Patient-Derived Xenograft Models of Glioblastoma. Mol Imaging 2016 0.78
23 Variations in genes involved in immune response checkpoints and association with outcomes in patients with resected colorectal liver metastases. Pharmacogenomics J 2015 0.77
24 Antiviral and Immunoregulatory Effects of Indoleamine-2,3-Dioxygenase in Hepatitis C Virus Infection. J Innate Immun 2015 0.76
25 European Cancer Congress 2015. P T 2015 0.75
26 Metabolic regulation of immune responses: therapeutic opportunities. J Clin Invest 2016 0.75
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