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Chemoradiation Followed by Durvalumab in Poor Risk and/or Elderly Patients With Stage III NSCLC (ESR1814205)
Clinical Trial ID NCT04441138
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🔗 Visit the ClinicalTrials.gov page for NCT04441138
Top papers
Rank
Title
Journal
Year
PubWeight™
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1
Safety, activity, and immune correlates of anti-PD-1 antibody in cancer.
N Engl J Med
2012
52.99
2
Safety and activity of anti-PD-L1 antibody in patients with advanced cancer.
N Engl J Med
2012
35.24
3
The blockade of immune checkpoints in cancer immunotherapy.
Nat Rev Cancer
2012
24.94
4
Signatures of mutational processes in human cancer.
Nature
2013
21.63
5
PD-1 and its ligands in tolerance and immunity.
Annu Rev Immunol
2008
19.24
6
Nivolumab plus ipilimumab in advanced melanoma.
N Engl J Med
2013
17.53
7
Involvement of PD-L1 on tumor cells in the escape from host immune system and tumor immunotherapy by PD-L1 blockade.
Proc Natl Acad Sci U S A
2002
12.39
8
MPDL3280A (anti-PD-L1) treatment leads to clinical activity in metastatic bladder cancer.
Nature
2014
10.49
9
Survival, durable tumor remission, and long-term safety in patients with advanced melanoma receiving nivolumab.
J Clin Oncol
2014
9.86
10
Programmed death-1 ligand 1 interacts specifically with the B7-1 costimulatory molecule to inhibit T cell responses.
Immunity
2007
8.94
11
The three Es of cancer immunoediting.
Annu Rev Immunol
2004
8.20
12
Inhibitory B7-family molecules in the tumour microenvironment.
Nat Rev Immunol
2008
8.17
13
Blockade of B7-H1 and PD-1 by monoclonal antibodies potentiates cancer therapeutic immunity.
Cancer Res
2005
4.94
14
Control of peripheral T-cell tolerance and autoimmunity via the CTLA-4 and PD-1 pathways.
Immunol Rev
2008
3.18
15
Integrated NY-ESO-1 antibody and CD8+ T-cell responses correlate with clinical benefit in advanced melanoma patients treated with ipilimumab.
Proc Natl Acad Sci U S A
2011
2.90
16
The programmed death-1 ligand 1:B7-1 pathway restrains diabetogenic effector T cells in vivo.
J Immunol
2011
2.69
17
Split-course chemoradiotherapy for locally advanced non-small cell lung cancer: a single-institution experience of 144 patients.
J Thorac Oncol
2011
1.40
18
Rationale for fixed dosing of pertuzumab in cancer patients based on population pharmacokinetic analysis.
Pharm Res
2006
1.26
19
Blockade of B7-H1 or B7-DC induces an anti-tumor effect in a mouse pancreatic cancer model.
Int J Oncol
2009
1.26
20
Fixed dosing versus body size-based dosing of monoclonal antibodies in adult clinical trials.
J Clin Pharmacol
2009
1.25
21
Updated survival and outcomes for older adults with inoperable stage III non-small-cell lung cancer treated with cisplatin, etoposide, and concurrent chest radiation with or without consolidation docetaxel: analysis of a phase III trial from the Hoosier Oncology Group (HOG) and US Oncology.
Ann Oncol
2011
1.06
22
Identification and Characterization of MEDI4736, an Antagonistic Anti-PD-L1 Monoclonal Antibody.
Cancer Immunol Res
2015
1.01
23
Fixed dosing versus body size-based dosing of therapeutic peptides and proteins in adults.
J Clin Pharmacol
2011
0.89
24
Analysis of duration of response in oncology trials.
Contemp Clin Trials
2007
0.85
25
Impact of Intensity-Modulated Radiation Therapy Technique for Locally Advanced Non-Small-Cell Lung Cancer: A Secondary Analysis of the NRG Oncology RTOG 0617 Randomized Clinical Trial.
J Clin Oncol
2016
0.85
26
Population pharmacokinetics of sifalimumab, an investigational anti-interferon-α monoclonal antibody, in systemic lupus erythematosus.
Clin Pharmacokinet
2013
0.82
27
Mechanisms of immune evasion and current status of checkpoint inhibitors in non-small cell lung cancer.
Cancer Med
2016
0.80
28
Patterns of locoregional failure in stage III non-small cell lung cancer treated with definitive chemoradiation therapy.
Pract Radiat Oncol
2014
0.79
29
Anti-tumor immunotherapy by blockade of the PD-1/PD-L1 pathway with recombinant human PD-1-IgV.
Cytotherapy
2008
0.78
30
Durvalumab after Chemoradiotherapy in Stage III Non-Small-Cell Lung Cancer.
N Engl J Med
2017
0.75
31
Association between intensity modulated radiotherapy and survival in patients with stage III non-small cell lung cancer treated with chemoradiotherapy.
Lung Cancer
2017
0.75
32
Pooled Analysis of Individual Patient Data on Concurrent Chemoradiotherapy for Stage III Non-Small-Cell Lung Cancer in Elderly Patients Compared With Younger Patients Who Participated in US National Cancer Institute Cooperative Group Studies.
J Clin Oncol
2017
0.75
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