PubRank

Cystic Fibrosis Blood Neutrophils (MUCO-PNN)

Clinical Trial ID NCT04970225

PubWeight™ 0.00‹?›

🔗 Visit the ClinicalTrials.gov page for NCT04970225

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Neutrophils in the activation and regulation of innate and adaptive immunity. Nat Rev Immunol 2011 6.96
2 Early pulmonary inflammation in infants with cystic fibrosis. Am J Respir Crit Care Med 1995 6.56
3 Effects of reduced mucus oxygen concentration in airway Pseudomonas infections of cystic fibrosis patients. J Clin Invest 2002 6.35
4 Inflammatory resolution: new opportunities for drug discovery. Nat Rev Drug Discov 2004 5.08
5 Myeloid-derived suppressor cell heterogeneity and subset definition. Curr Opin Immunol 2010 4.62
6 Cyclin-dependent kinase inhibitors enhance the resolution of inflammation by promoting inflammatory cell apoptosis. Nat Med 2006 3.79
7 Neutrophils: molecules, functions and pathophysiological aspects. Lab Invest 2000 3.60
8 Phagocyte receptors for apoptotic cells: recognition, uptake, and consequences. J Clin Invest 2001 2.96
9 A subset of neutrophils in human systemic inflammation inhibits T cell responses through Mac-1. J Clin Invest 2011 2.52
10 Cytokine-mediated Bax deficiency and consequent delayed neutrophil apoptosis: a general mechanism to accumulate effector cells in inflammation. Proc Natl Acad Sci U S A 1999 1.56
11 Neutrophils in cystic fibrosis. Thorax 2009 1.51
12 Functional heterogeneity and differential priming of circulating neutrophils in human experimental endotoxemia. J Leukoc Biol 2010 1.42
13 Cystic fibrosis lung inflammation: early, sustained, and severe. Am J Respir Crit Care Med 1995 1.36
14 Regulating neutrophil apoptosis: new players enter the game. Trends Immunol 2011 1.33
15 Proliferating cell nuclear antigen acts as a cytoplasmic platform controlling human neutrophil survival. J Exp Med 2010 1.27
16 Immune suppression by neutrophils and granulocytic myeloid-derived suppressor cells: similarities and differences. Cell Mol Life Sci 2013 1.26
17 Presence of proteinase 3 in secretory vesicles: evidence of a novel, highly mobilizable intracellular pool distinct from azurophil granules. Blood 1999 1.23
18 In cystic fibrosis homozygotes and heterozygotes, neutrophil apoptosis is delayed and modulated by diamide or roscovitine: evidence for an innate neutrophil disturbance. J Innate Immun 2010 1.05
19 Prolonged survival of neutrophils from patients with Delta F508 CFTR mutations. Thorax 2008 1.05
20 Disturbed myeloperoxidase-dependent activity of neutrophils in cystic fibrosis homozygotes and heterozygotes, and its correction by amiloride. J Immunol 1996 1.00
21 Neutrophils in cystic fibrosis display a distinct gene expression pattern. Mol Med 2008 1.00
22 A functional analysis of PCNA-binding peptides derived from protein sequence, interaction screening and rational design. Oncogene 2006 0.95
23 Coronin-1 is associated with neutrophil survival and is cleaved during apoptosis: potential implication in neutrophils from cystic fibrosis patients. J Immunol 2009 0.93
24 The cystic fibrosis neutrophil: a specialized yet potentially defective cell. Arch Immunol Ther Exp (Warsz) 2011 0.92
25 Inflammation and CFTR: might neutrophils be the key in cystic fibrosis? Mediators Inflamm 1999 0.89
26 Metabolic adaptation of neutrophils in cystic fibrosis airways involves distinct shifts in nutrient transporter expression. J Immunol 2013 0.89
27 Targeting neutrophilic inflammation in severe neutrophilic asthma: can we target the disease-relevant neutrophil phenotype? J Leukoc Biol 2015 0.87
28 Nuclear-to-cytoplasmic relocalization of the proliferating cell nuclear antigen (PCNA) during differentiation involves a chromosome region maintenance 1 (CRM1)-dependent export and is a prerequisite for PCNA antiapoptotic activity in mature neutrophils. J Biol Chem 2012 0.86
29 RNA interference against CFTR affects HL60-derived neutrophil microbicidal function. Free Radic Biol Med 2010 0.85
30 How Neutrophils Shape Adaptive Immune Responses. Front Immunol 2015 0.84
31 Human neutrophils in the saga of cellular heterogeneity: insights and open questions. Immunol Rev 2016 0.83
32 Priming of blood neutrophils in children with cystic fibrosis: correlation between functional and phenotypic expression of opsonin receptors before and after platelet-activating factor priming. J Infect Dis 1999 0.82
33 Tyrosine kinase signaling pathways in neutrophils. Immunol Rev 2016 0.80
34 Targeting cytosolic proliferating cell nuclear antigen in neutrophil-dominated inflammation. Front Immunol 2012 0.79
35 Proliferating cell nuclear antigen in neutrophil fate. Immunol Rev 2016 0.78
36 Future treatment in patients with chronic obstructive pulmonary disease: to reverse or not to reverse steroid resistance-that is the question. J Allergy Clin Immunol 2014 0.77
37 Neutrophil-Expressed p21/waf1 Favors Inflammation Resolution in Pseudomonas aeruginosa Infection. Am J Respir Cell Mol Biol 2016 0.77
38 Low-density granulocytes: functionally distinct, immature neutrophils in rheumatoid arthritis with altered properties and defective TNF signalling. J Leukoc Biol 2016 0.77
39 Modulating Innate and Adaptive Immunity by (R)-Roscovitine: Potential Therapeutic Opportunity in Cystic Fibrosis. J Innate Immun 2016 0.75
40 Cytoplasmic proliferating cell nuclear antigen connects glycolysis and cell survival in acute myeloid leukemia. Sci Rep 2016 0.75
41 Early Expansion of Circulating Granulocytic Myeloid-derived Suppressor Cells Predicts Development of Nosocomial Infections in Septic Patients. Am J Respir Crit Care Med 2017 0.75
42 Lumacaftor/ivacaftor, a novel agent for the treatment of cystic fibrosis patients who are homozygous for the F580del CFTR mutation. Expert Rev Clin Pharmacol 2017 0.75
43 Neutrophils in the innate immunity conundrum of cystic fibrosis: a CFTR-related matter? J Innate Immun 2013 0.75
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