| Rank |
Title |
Year |
PubWeight™‹?› |
|
1
|
Pharmacogenomics: the promise of personalized medicine.
|
2000
|
2.63
|
|
2
|
Assuring quality and performance of sustained and controlled release parenterals: workshop report.
|
2002
|
1.84
|
|
3
|
Comparison of stepwise covariate model building strategies in population pharmacokinetic-pharmacodynamic analysis.
|
2002
|
1.72
|
|
4
|
DNA/polyethylenimine transfection particles: influence of ligands, polymer size, and PEGylation on internalization and gene expression.
|
2001
|
1.66
|
|
5
|
The Venus flytrap of periplasmic binding proteins: an ancient protein module present in multiple drug receptors.
|
1999
|
1.47
|
|
6
|
Nutraceutical--definition and introduction.
|
2003
|
1.38
|
|
7
|
Transfection efficiency and toxicity of polyethylenimine in differentiated Calu-3 and nondifferentiated COS-1 cell cultures.
|
2002
|
1.36
|
|
8
|
Targeted prodrug design to optimize drug delivery.
|
2000
|
1.36
|
|
9
|
Assessing the cost-effectiveness of pharmacogenomics.
|
2000
|
1.30
|
|
10
|
Role of MRP4 and MRP5 in biology and chemotherapy.
|
2002
|
1.22
|
|
11
|
Nonlinearity detection: advantages of nonlinear mixed-effects modeling.
|
2000
|
1.20
|
|
12
|
Direct pelletization in a rotary processor controlled by torque measurements. II: effects of changes in the content of microcrystalline cellulose.
|
2000
|
1.16
|
|
13
|
Pharmacodynamic modeling of chemotherapeutic effects: application of a transit compartment model to characterize methotrexate effects in vitro.
|
2002
|
1.16
|
|
14
|
Wet granulation fine particle ethylcellulose tablets: effect of production variables and mathematical modeling of drug release.
|
2003
|
1.15
|
|
15
|
A novel in vitro release method for submicron sized dispersed systems.
|
1999
|
1.14
|
|
16
|
Rheology and stability of water-in-oil-in-water multiple emulsions containing Span 83 and Tween 80.
|
2003
|
1.13
|
|
17
|
Protein binding predictions in infants.
|
2002
|
1.11
|
|
18
|
Spatial expression patterns of peptide transporters in the human and rat gastrointestinal tracts, Caco-2 in vitro cell culture model, and multiple human tissues.
|
2001
|
1.11
|
|
19
|
A photo-crosslinked poly(vinyl alcohol) hydrogel growth factor release vehicle for wound healing applications.
|
2003
|
1.09
|
|
20
|
Influence of drug release properties of conventional solid dosage forms on the systemic exposure of highly soluble drugs.
|
2001
|
1.06
|
|
21
|
Time- and concentration-dependent penetration of doxorubicin in prostate tumors.
|
2001
|
1.06
|
|
22
|
Pharmacokinetic/pharmacodynamic integration in drug development and dosage-regimen optimization for veterinary medicine.
|
2002
|
1.05
|
|
23
|
A short term (accelerated release) approach to evaluate peptide release from PLGA depot-formulations.
|
1999
|
1.04
|
|
24
|
Beta-cyclodextrin complexes of celecoxib: molecular-modeling, characterization, and dissolution studies.
|
2004
|
1.04
|
|
25
|
Encapsulation of water-insoluble drug by a cross-linking technique: effect of process and formulation variables on encapsulation efficiency, particle size, and in vitro dissolution rate.
|
2004
|
1.04
|
|
26
|
Mechanisms of aggregate formation and carbohydrate excipient stabilization of lyophilized humanized monoclonal antibody formulations.
|
2003
|
1.03
|
|
27
|
Physiologically based pharmacokinetics in drug development and regulatory science: a workshop report (Georgetown University, Washington, DC, May 29-30, 2002).
|
2004
|
1.03
|
|
28
|
Visualization of the lipid barrier and measurement of lipid pathlength in human stratum corneum.
|
2001
|
1.03
|
|
29
|
Which concentration of the inhibitor should be used to predict in vivo drug interactions from in vitro data?
|
2002
|
1.02
|
|
30
|
Deposition of nanoparticles in the arterial vessel by porous balloon catheters: localization by confocal laser scanning microscopy and transmission electron microscopy.
|
2002
|
1.02
|
|
31
|
Light scattering investigations on dilute nonionic oil-in-water microemulsions.
|
2000
|
1.02
|
|
32
|
Maturation and growth of renal function: dosing renally cleared drugs in children.
|
2000
|
1.01
|
|
33
|
Use of FT-NIR transmission spectroscopy for the quantitative analysis of an active ingredient in a translucent pharmaceutical topical gel formulation.
|
2001
|
1.01
|
|
34
|
Particle size analysis of concentrated phospholipid microemulsions I. Total intensity light scattering.
|
2000
|
1.01
|
|
35
|
Interspecies considerations in the evaluation of human food safety for veterinary drugs.
|
2002
|
1.01
|
|
36
|
Comparative evaluation of the degree of indomethacin crystallinity by chemoinfometrical Fourier-transformed [corrected] near-infrared spectroscopy and conventional powder X-ray diffractometry.
|
2000
|
1.00
|
|
37
|
The composite solubility versus pH profile and its role in intestinal absorption prediction.
|
2003
|
1.00
|
|
38
|
An in vitro examination of the impact of polyethylene glycol 400, Pluronic P85, and vitamin E d-alpha-tocopheryl polyethylene glycol 1000 succinate on P-glycoprotein efflux and enterocyte-based metabolism in excised rat intestine.
|
2002
|
1.00
|
|
39
|
Design and synthesis of the CB1 selective cannabinoid antagonist AM281: a potential human SPECT ligand.
|
1999
|
1.00
|
|
40
|
Low molecular weight protamine (LMWP) as nontoxic heparin/low molecular weight heparin antidote (I): preparation and characterization.
|
2001
|
0.99
|
|
41
|
Influence of the degree of polymerization on the behavior of cellulose during homogenization and extrusion/spheronization.
|
2000
|
0.99
|
|
42
|
Comparison of the gravimetric, phenol red, and 14C-PEG-3350 methods to determine water absorption in the rat single-pass intestinal perfusion model.
|
2001
|
0.99
|
|
43
|
Evaluation of USP apparatus 3 for dissolution testing of immediate-release products.
|
2002
|
0.98
|
|
44
|
Evolutionary relationships among G protein-coupled receptors using a clustered database approach.
|
2001
|
0.98
|
|
45
|
Receptor-targeted gene delivery via folate-conjugated polyethylenimine.
|
1999
|
0.97
|
|
46
|
Permeability classification of representative fluoroquinolones by a cell culture method.
|
2004
|
0.96
|
|
47
|
Effect of rise in simulated inspiratory flow rate and carrier particle size on powder emptying from dry powder inhalers.
|
2000
|
0.96
|
|
48
|
Evaluation of the antioxidant activity of different flavonoids by the chemiluminescence method.
|
2003
|
0.96
|
|
49
|
Properties of microcrystalline cellulose and powder cellulose after extrusion/spheronization as studied by fourier transform Raman spectroscopy and environmental scanning electron microscopy.
|
2003
|
0.96
|
|
50
|
Lipid-based supramolecular systems for topical application: a preformulatory study.
|
2003
|
0.96
|