(S)-(-)-Cotinine, the major brain metabolite of nicotine, stimulates nicotinic receptors to evoke [3H]dopamine release from rat striatal slices in a calcium-dependent manner.

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Published in J Pharmacol Exp Ther on March 01, 1999

Authors

L P Dwoskin1, L Teng, S T Buxton, P A Crooks

Author Affiliations

1: College of Pharmacy and Graduate Center for Toxicology, University for Kentucky, Lexington 40536-0082, USA. ldwoskin@pop.uky.edu

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