Published in J Natl Cancer Inst on February 17, 1999
The Effects of Lycopene on High Risk Prostatic Tissue | NCT01443026
Identification of New Biomarkers of Banana and Tomato Intake (BioBanaTom) | NCT03581955
An alternative pathway to beta -carotene formation in plant chromoplasts discovered by map-based cloning of beta and old-gold color mutations in tomato. Proc Natl Acad Sci U S A (2000) 2.26
Perspectives for cancer prevention with natural compounds. J Clin Oncol (2009) 1.99
The cauliflower Or gene encodes a DnaJ cysteine-rich domain-containing protein that mediates high levels of beta-carotene accumulation. Plant Cell (2006) 1.80
Modifiable risk factors for cancer. Br J Cancer (2004) 1.72
Evaluation of transgenic tomato plants expressing an additional phytoene synthase in a fruit-specific manner. Proc Natl Acad Sci U S A (2002) 1.71
Tomato lycopene and its role in human health and chronic diseases. CMAJ (2000) 1.39
Genome mapping and molecular breeding of tomato. Int J Plant Genomics (2007) 1.36
Effects of variety on the quality of tomato stored under ambient conditions. J Food Sci Technol (2011) 1.36
Identification and quantification of apo-lycopenals in fruits, vegetables, and human plasma. J Agric Food Chem (2010) 1.30
Multitargeted therapy of cancer by lycopene. Cancer Lett (2008) 1.19
Role of nuclear factor κB-mediated inflammatory pathways in cancer-related symptoms and their regulation by nutritional agents. Exp Biol Med (Maywood) (2011) 1.18
Association between optimism and serum antioxidants in the midlife in the United States study. Psychosom Med (2012) 1.08
Tomato-based food products for prostate cancer prevention: what have we learned? Cancer Metastasis Rev (2010) 1.08
Phytoene, Phytofluene, and Lycopene from Tomato Powder Differentially Accumulate in Tissues of Male Fisher 344 Rats. Nutr Res (2007) 1.05
Dietary lycopene and tomato extract supplementations inhibit nonalcoholic steatohepatitis-promoted hepatocarcinogenesis in rats. Int J Cancer (2010) 1.02
Diet, smoking and lung cancer: a case-control study of 1000 cases and 1500 controls in South-West England. Br J Cancer (2001) 1.02
Resonance Raman detection of carotenoid antioxidants in living human tissue. J Biomed Opt (2006) 1.00
Are diet-prostate cancer associations mediated by the IGF axis? A cross-sectional analysis of diet, IGF-I and IGFBP-3 in healthy middle-aged men. Br J Cancer (2003) 1.00
Results of a Randomized Clinical Trial of the Action of Several Doses of Lycopene in Localized Prostate Cancer: Administration Prior to Radical Prostatectomy. Clin Med Urol (2008) 0.99
Lycopene metabolite, apo-10'-lycopenoic acid, inhibits diethylnitrosamine-initiated, high fat diet-promoted hepatic inflammation and tumorigenesis in mice. Cancer Prev Res (Phila) (2013) 0.98
Enzymatic metabolites of lycopene induce Nrf2-mediated expression of phase II detoxifying/antioxidant enzymes in human bronchial epithelial cells. Int J Cancer (2008) 0.97
Lycopene suppresses the lipopolysaccharide-induced phenotypic and functional maturation of murine dendritic cells through inhibition of mitogen-activated protein kinases and nuclear factor-kappaB. Immunology (2004) 0.97
An update on the health effects of tomato lycopene. Annu Rev Food Sci Technol (2010) 0.95
Chemopreventive potential of natural compounds in head and neck cancer. Nutr Cancer (2010) 0.95
Antioxidant effects of lycopene in African American men with prostate cancer or benign prostate hyperplasia: a randomized, controlled trial. Cancer Prev Res (Phila) (2011) 0.94
Redefining the impact of nutrition on breast cancer incidence: is epigenetics involved? Nutr Res Rev (2012) 0.93
Potent antioxidative activity of lycopene: A potential role in scavenging hypochlorous acid. Free Radic Biol Med (2010) 0.93
Epigenetic modifications by dietary phytochemicals: implications for personalized nutrition. Pharmacol Ther (2012) 0.92
Multiple molecular and cellular mechanisms of action of lycopene in cancer inhibition. Evid Based Complement Alternat Med (2013) 0.91
Phytochemicals as Innovative Therapeutic Tools against Cancer Stem Cells. Int J Mol Sci (2015) 0.91
Expression of phytoene synthase gene (Psy) is enhanced during fruit ripening of Cara Cara navel orange (Citrus sinensis Osbeck). Plant Cell Rep (2007) 0.89
Non-alcoholic steatohepatitis and hepatocellular carcinoma: implications for lycopene intervention. Nutrients (2013) 0.89
Nanostructured metal oxide gas sensors, a survey of applications carried out at SENSOR lab, Brescia (Italy) in the security and food quality fields. Sensors (Basel) (2012) 0.89
Regulation of carotenoid accumulation and the expression of carotenoid metabolic genes in citrus juice sacs in vitro. J Exp Bot (2011) 0.89
Whole food versus supplement: comparing the clinical evidence of tomato intake and lycopene supplementation on cardiovascular risk factors. Adv Nutr (2014) 0.89
Comparison of lycopene and tomato effects on biomarkers of oxidative stress in vitamin E deficient rats. Eur J Nutr (2007) 0.88
A multi-targeted approach to suppress tumor-promoting inflammation. Semin Cancer Biol (2015) 0.87
Chemoprevention of premalignant and malignant lesions of oral cavity: Recent trends. Eur J Dent (2013) 0.87
Use of Time-Resolved Fluorescence to Monitor Bioactive Compounds in Plant Based Foodstuffs. Biosensors (Basel) (2015) 0.87
Antioxidant status and immune activity of glycyrrhizin in allergic rhinitis mice. Int J Mol Sci (2011) 0.87
Plant phytochemicals as epigenetic modulators: role in cancer chemoprevention. AAPS J (2013) 0.86
Herbicide treatments alter carotenoid profiles for 14C tracer production from tomato ( Solanum lycopersicum cv. VFNT cherry) cell cultures. J Agric Food Chem (2009) 0.86
A dose-response study on the effects of purified lycopene supplementation on biomarkers of oxidative stress. J Am Coll Nutr (2008) 0.86
Intragenic enhancers and suppressors of phytoene desaturase mutations in Chlamydomonas reinhardtii. PLoS One (2012) 0.86
Effect of domestic cooking on human bioavailability of naringenin, chlorogenic acid, lycopene and beta-carotene in cherry tomatoes. Eur J Nutr (2004) 0.85
Lycopene and other carotenoid intake in relation to risk of uterine leiomyomata. Am J Obstet Gynecol (2007) 0.85
The prevention of hereditary breast and ovarian cancer: a personal view. Hered Cancer Clin Pract (2004) 0.84
Modest induction of phase 2 enzyme activity in the F-344 rat prostate. BMC Cancer (2006) 0.84
Dietary factors and risk for advanced prostate cancer. Eur J Cancer Prev (2014) 0.83
Sapodilla plum (Achras sapota) induces apoptosis in cancer cell lines and inhibits tumor progression in mice. Sci Rep (2014) 0.83
Lycopene attenuated hepatic tumorigenesis via differential mechanisms depending on carotenoid cleavage enzyme in mice. Cancer Prev Res (Phila) (2014) 0.82
Expression and functional analysis of two lycopene β-cyclases from citrus fruits. Planta (2012) 0.82
Comparative multiple dose plasma kinetics of lycopene administered in tomato juice, tomato soup or lycopene tablets. Eur J Nutr (2004) 0.81
Accumulation of Flavonols over Hydroxycinnamic Acids Favors Oxidative Damage Protection under Abiotic Stress. Front Plant Sci (2016) 0.81
Lycopene and apo-10'-lycopenoic acid have differential mechanisms of protection against hepatic steatosis in β-carotene-9',10'-oxygenase knockout male mice. J Nutr (2014) 0.80
Carotenoid accumulation in postharvest "Cara Cara" navel orange (Citrus sinensis Osbeck) fruits stored at different temperatures was transcriptionally regulated in a tissue-dependent manner. Plant Cell Rep (2012) 0.80
High-resolution genetic and physical mapping of the cauliflower high-beta-carotene gene Or ( Orange). Mol Genet Genomics (2003) 0.79
Dietary terpenoids and prostate cancer chemoprevention. Front Biosci (2008) 0.79
Comparison of baseline dietary intake of Hispanic and matched non-Hispanic white breast cancer survivors enrolled in the Women's Healthy Eating and Living study. J Am Diet Assoc (2008) 0.78
Tomatoes, lycopene-containing foods and cancer risk. Br J Cancer (2011) 0.77
Re: Tomatoes, tomato-based products, lycopene, and prostate cancer: review of the epidemiologic literature. J Natl Cancer Inst (1999) 0.77
Opportunities for prevention of prostate cancer: genetics, chemoprevention, and dietary intervention. Rev Urol (2002) 0.77
Effects of tomato and soy on serum adipokine concentrations in postmenopausal women at increased breast cancer risk: a cross-over dietary intervention trial. J Clin Endocrinol Metab (2014) 0.77
Retinoid and carotenoid status in serum and liver among patients at high-risk for liver cancer. BMC Gastroenterol (2016) 0.76
New agents for prevention of ultraviolet-induced nonmelanoma skin cancer. Semin Cutan Med Surg (2011) 0.76
Animal models in carotenoids research and lung cancer prevention. Transl Oncol (2011) 0.76
Development of slow release formulations of β-carotene employing amphiphilic polymers and their release kinetics study in water and different pH conditions. J Food Sci Technol (2015) 0.75
Chemoprevention and prostate cancer. Rev Urol (2003) 0.75
Identification of Yellow Pigmentation Genes in Brassica rapa ssp. pekinensis Using Br300 Microarray. Int J Genomics (2014) 0.75
Anti-inflammatory effect of lycopene in SW480 human colorectal cancer cells. Nutr Res Pract (2017) 0.75
Molecular Targeted Therapies Using Botanicals for Prostate Cancer Chemoprevention. Transl Med (Sunnyvale) (2012) 0.75
Anti-carcinogenic and Anti-bacterial Properties of Selected Spices: Implications in Oral Health. Clin Nutr Res (2015) 0.75
Evaluation of Antioxidative Activity of Various Levels of Ethanol Extracted Tomato Powder and Application to Pork Patties. Korean J Food Sci Anim Resour (2017) 0.75
Bioactive Compounds and Antioxidant Activity in Different Grafted Varieties of Bell Pepper. Antioxidants (Basel) (2015) 0.75
Molecular characterization of carotenoid biosynthetic genes and carotenoid accumulation in Scutellaria baicalensis Georgi. EXCLI J (2014) 0.75
Tomato as a Source of Carotenoids and Polyphenols Targeted to Cancer Prevention. Cancers (Basel) (2016) 0.75
Intravenous Administration of Lycopene, a Tomato Extract, Protects against Myocardial Ischemia-Reperfusion Injury. Nutrients (2016) 0.75
Influence of Heat Treatments on Carotenoid Content of Cherry Tomatoes. Foods (2013) 0.75
Analysis of carotenoid accumulation and expression of carotenoid biosynthesis genes in different organs of Chinese cabbage (Brassica rapa subsp. pekinensis). EXCLI J (2012) 0.75
Germline genetic profiling in prostate cancer: latest developments and potential clinical applications. Future Sci OA (2015) 0.75
β-Carotene 9',10' Oxygenase Modulates the Anticancer Activity of Dietary Tomato or Lycopene on Prostate Carcinogenesis in the TRAMP Model. Cancer Prev Res (Phila) (2016) 0.75
Advances in prostate cancer treatment: highlights from the 2nd international prostate cancer congress, st. Thomas, u.s. Virgin islands, july 17-20, 2002. Rev Urol (2003) 0.75
Protective Effects of Sweet Orange, Unshiu Mikan, and Mini Tomato Juice Powders on t-BHP-Induced Oxidative Stress in HepG2 Cells. Prev Nutr Food Sci (2016) 0.75
Fruitflow(®): the first European Food Safety Authority-approved natural cardio-protective functional ingredient. Eur J Nutr (2016) 0.75
Natural variation in expression of genes associated with carotenoid biosynthesis and accumulation in cassava (Manihot esculenta Crantz) storage root. BMC Plant Biol (2016) 0.75
Increased dietary and circulating lycopene are associated with reduced prostate cancer risk: a systematic review and meta-analysis. Prostate Cancer Prostatic Dis (2017) 0.75
Naringenin Impairs Two-Pore Channel 2 Activity And Inhibits VEGF-Induced Angiogenesis. Sci Rep (2017) 0.75