Published in Nucleic Acids Res on April 15, 1999
Digital PCR. Proc Natl Acad Sci U S A (1999) 10.54
Survey and summary: The applications of universal DNA base analogues. Nucleic Acids Res (2001) 1.62
Quantification of the detrimental effect of a single primer-template mismatch by real-time PCR using the 16S rRNA gene as an example. Appl Environ Microbiol (2008) 1.42
The effect of primer-template mismatches on the detection and quantification of nucleic acids using the 5' nuclease assay. J Mol Diagn (2009) 1.16
Competitive enzymatic reaction to control allele-specific extensions. Nucleic Acids Res (2005) 1.09
Genotyping by apyrase-mediated allele-specific extension. Nucleic Acids Res (2001) 1.01
NMR structure of a DNA duplex containing nucleoside analog 1-(2'-deoxy-beta-D-ribofuranosyl)-3-nitropyrrole and the structure of the unmodified control. Nucleic Acids Res (2000) 0.86
Hemi-nested touchdown PCR combined with primer-template mismatch PCR for rapid isolation and sequencing of low molecular weight glutenin subunit gene family from a hexaploid wheat BAC library. BMC Genet (2007) 0.81
G-quadruplex-generating polymerase chain reaction for visual colorimetric detection of amplicons. Anal Biochem (2013) 0.77
Selectivity of Enzymatic Conversion of Oligonucleotide Probes during Nucleotide Polymorphism Analysis of DNA. Acta Naturae (2010) 0.75
PCR Strategies for Complete Allele Calling in Multigene Families Using High-Throughput Sequencing Approaches. PLoS One (2016) 0.75
Detecting colorectal cancer in stool with the use of multiple genetic targets. J Natl Cancer Inst (2001) 2.93
Single-stranded hexameric linkers: a system for in-phase insertion mutagenesis and protein engineering. Gene (1985) 2.73
Improving the fidelity of Thermus thermophilus DNA ligase. Nucleic Acids Res (1996) 2.58
Two-codon insertion mutagenesis of plasmid genes by using single-stranded hexameric oligonucleotides. Proc Natl Acad Sci U S A (1985) 2.50
Universal DNA microarray method for multiplex detection of low abundance point mutations. J Mol Biol (1999) 2.47
Transformasomes: specialized membranous structures that protect DNA during Haemophilus transformation. Proc Natl Acad Sci U S A (1983) 2.35
Biochemical properties of a high fidelity DNA ligase from Thermus species AK16D. Nucleic Acids Res (1999) 1.89
Genetic transformation of Streptococcus pneumoniae by heterologous plasmid deoxyribonucleic acid. J Bacteriol (1980) 1.74
Directional transport and integration of donor DNA in Haemophilus influenzae transformation. Proc Natl Acad Sci U S A (1983) 1.71
Classification of BRCA1 missense variants of unknown clinical significance. J Med Genet (2005) 1.71
NeuroD2 and neuroD3: distinct expression patterns and transcriptional activation potentials within the neuroD gene family. Mol Cell Biol (1996) 1.67
Universal DNA array detection of small insertions and deletions in BRCA1 and BRCA2. Nat Biotechnol (2000) 1.66
Numerical scoring of self-care status of patients. Arch Phys Med Rehabil (1965) 1.65
Long-term behavioral and neuronal cross-sensitization to amphetamine induced by repeated brief social defeat stress: Fos in the ventral tegmental area and amygdala. Neuroscience (2004) 1.58
Staphylococcal plasmids that replicate and express erythromycin resistance in both Streptococcus pneumoniae and Escherichia coli. Proc Natl Acad Sci U S A (1982) 1.54
Identification of non-amplifying CYP21 genes when using PCR-based diagnosis of 21-hydroxylase deficiency in congenital adrenal hyperplasia (CAH) affected pedigrees. Hum Mol Genet (1996) 1.51
Multiplex PCR/LDR for detection of K-ras mutations in primary colon tumors. Oncogene (1999) 1.49
Phencyclidine (angel dust)/sigma "opiate" receptor: visualization by tritium-sensitive film. Proc Natl Acad Sci U S A (1981) 1.39
Transcriptional analysis of the active X-chromosome in normal and clonal hematopoiesis. Blood (1993) 1.31
Short- and long-term effects of intermittent social defeat stress on brain-derived neurotrophic factor expression in mesocorticolimbic brain regions. Neuroscience (2010) 1.27
Detection of steroid 21-hydroxylase alleles using gene-specific PCR and a multiplexed ligation detection reaction. Genomics (1995) 1.26
Ligase chain reaction (LCR)--overview and applications. PCR Methods Appl (1994) 1.24
Photoaffinity cross-linking of TaqI restriction endonuclease using an aryl azide linked to the phosphate backbone. Gene (1995) 1.21
Identification of essential residues in Thermus thermophilus DNA ligase. Nucleic Acids Res (1996) 1.21
Discrimination of Listeria monocytogenes from other Listeria species by ligase chain reaction. Appl Environ Microbiol (1992) 1.21
Multiple cleavage activities of endonuclease V from Thermotoga maritima: recognition and strand nicking mechanism. Biochemistry (2001) 1.17
Detection of Listeria monocytogenes with a nonisotopic polymerase chain reaction-coupled ligase chain reaction assay. Appl Environ Microbiol (1993) 1.16
Ligase detection reaction for identification of low abundance mutations. Clin Biochem (1999) 1.14
Degeneration of the human Betz cell due to amyotrophic lateral sclerosis. Exp Neurol (1979) 1.14
Detection and serotyping of dengue virus in serum samples by multiplex reverse transcriptase PCR-ligase detection reaction assay. J Clin Microbiol (2008) 1.13
Use of 1,2,4-dithiazolidine-3,5-dione (DtsNH) and 3-ethoxy-1,2,4-dithiazoline-5-one (EDITH) for synthesis of phosphorothioate-containing oligodeoxyribonucleotides. Nucleic Acids Res (1996) 1.12
Mutation detection in K-ras, BRCA1, BRCA2, and p53 using PCR/LDR and a universal DNA microarray. Ann N Y Acad Sci (2000) 1.08
Characterization of steady state, single-turnover, and binding kinetics of the TaqI restriction endonuclease. J Biol Chem (1992) 1.05
Automated, multiplex assay for high-frequency microsatellite instability in colorectal cancer. J Clin Oncol (2003) 1.04
Hyperkalemic periodic paralysis: rapid molecular diagnosis and relationship of genotype to phenotype in 12 families. Neurology (1993) 1.03
Mutagens in feces from vegetarians and non-vegetarians. Mutat Res (1981) 1.01
Functionalized tricarbocyanine dyes as near-infrared fluorescent probes for biomolecules. Bioconjug Chem (1997) 0.99
Ligation reaction specificities of an NAD(+)-dependent DNA ligase from the hyperthermophile Aquifex aeolicus. Nucleic Acids Res (2000) 0.97
Perinatal opiate treatment delays growth of cortical dendrites. Neurosci Lett (1990) 0.97
The clinical effect of salazosulphapyridine (Salazopyrin r) in Crohn's disease. A controlled double-blind study. Scand J Gastroenterol (1974) 0.97
Social defeat stress increases expression of mu-opioid receptor mRNA in rat ventral tegmental area. Neuroreport (1999) 0.96
Ligase-based detection of mononucleotide repeat sequences. Nucleic Acids Res (1999) 0.95
Development of multiplex PCR-ligase detection reaction assay for detection of West Nile virus. J Clin Microbiol (2008) 0.95
Serotonin, but not dopamine, metabolites are increased in selected brain regions of subordinate male rats in a colony environment. Brain Res (1991) 0.94
Effects of opiates on neuronal development in the rat cerebral cortex. Brain Res Bull (1993) 0.94
Morphologic evidence for a delay of neuronal maturation in fetal alcohol exposure. Exp Neurol (1981) 0.92
The long-term prophylactic effect of salazosulphapyridine (Salazopyrin) in primarily resected patients with Crohn's disease. A controlled double-blind trial. Scand J Gastroenterol (1978) 0.91
Molecular genetic and genetic correlations in sodium channelopathies: lack of founder effect and evidence for a second gene. Am J Hum Genet (1993) 0.89
Cocaine abstinence following chronic treatment alters cerebral metabolism in dopaminergic reward regions. Bromocriptine enhances recovery. Neuropsychopharmacology (1991) 0.89
Gonadal steroid hormone regulation of proopiomelanocortin gene expression in arcuate neurons that innervate the medial preoptic area of the rat. Neuroendocrinology (1995) 0.89
Reduction of zif268 messenger RNA expression during prolonged withdrawal following "binge" cocaine self-administration in rats. Neuroscience (2000) 0.88
Identification of TaqI endonuclease active site residues by Fe2+-mediated oxidative cleavage. J Biol Chem (1998) 0.88
Efficient introduction of phosphorothioates into RNA oligonucleotides by 3-ethoxy-1,2,4-dithiazoline-5-one (EDITH). Nucleic Acids Res (1996) 0.87
Confirmation of mutant alpha 1 Na,K-ATPase gene and transcript in Dahl salt-sensitive/JR rats. Hypertension (1994) 0.86
Nucleotide sequences and gene organization of TaqI endonuclease isoschizomers from Thermus sp. SM32 and Thermus filiformis Tok6A1. Gene (1997) 0.86
Improved fidelity of thermostable ligases for detection of microsatellite repeat sequences using nucleoside analogs. Nucleic Acids Res (1999) 0.85
Intermittent social defeat stress enhances mesocorticolimbic ΔFosB/BDNF co-expression and persistently activates corticotegmental neurons: implication for vulnerability to psychostimulants. Neuroscience (2012) 0.85
Near-infrared heavy-atom-modified fluorescent dyes for base-calling in DNA-sequencing applications using temporal discrimination. Anal Chem (1998) 0.85
Cloning and thermostability of TaqI endonuclease isoschizomers from Thermus species SM32 and Thermus filiformis Tok6A1. Biochem J (1998) 0.84
Development of the brain stem reticular core: an assessment of dendritic state and configuration in the perinatal rat. Brain Res (1981) 0.84
Stringent and relaxed specificities of TaqI endonuclease: interactions with metal cofactors and DNA sequences. Biochemistry (1995) 0.84
In vitro and in vivo studies of a promising antileukemic thymidine analogue, 5-hydroxymethyl-2' deoxyuridine. Biochem Pharmacol (1986) 0.83
[DLys(6)]-luteinizing hormone releasing hormone-curcumin conjugate inhibits pancreatic cancer cell growth in vitro and in vivo. Int J Cancer (2011) 0.83
Autoradiographic localization of dopamine D1 and D2 receptors in rat nucleus accumbens: resistance to differential rearing conditions. Neuroscience (1991) 0.83
MK-0457, an Aurora kinase and BCR-ABL inhibitor, is active in patients with BCR-ABL T315I leukemia. Leukemia (2012) 0.83
Genomic survey of prepulse inhibition in mouse chromosome substitution strains. Genes Brain Behav (2009) 0.81
The sexually dimorphic region of the preoptic area in rats contains denser opiate receptor binding sites in females. Brain Res (1984) 0.81
DNA recognition of base analogue and chemically modified substrates by the TaqI restriction endonuclease. J Biol Chem (1992) 0.80
Nucleotide analogs and new buffers improve a generalized method to enrich for low abundance mutations. Nucleic Acids Res (1999) 0.80
The disruptive effect of cocaine on prepulse inhibition is prevented by repeated administration in rats. Neuropsychopharmacology (2000) 0.80
The influence of pre- and postnatal undernutrition on the developing brain stem reticular core: a quantitative Golgi study. Brain Res (1981) 0.79
Synthesis of phosphonamide and thiophosphonamide dipeptides. J Am Chem Soc (2001) 0.79
Interaction of TaqI endonuclease with the phosphate backbone. Effects of stereospecific phosphate modification. J Biol Chem (1994) 0.79
Competitive (AP7) and non-competitive (MK-801) NMDA receptor antagonists differentially alter glucose utilization in rat cortex. Synapse (1991) 0.78
Genetic transformation of Streptococcus pneumoniae by DNA cloned into the single-stranded bacteriophage f1. J Bacteriol (1983) 0.78
Comparison of transformation mechanisms of Haemophilus parainfluenzae and Haemophilus influenzae. J Bacteriol (1985) 0.78
Gestational cocaine exposure increases opiate receptor binding in weanling offspring. Brain Res Dev Brain Res (1991) 0.78
Multiplex PCR-ligation detection reaction assay for simultaneous detection of drug resistance and toxin genes from Staphylococcus aureus, Enterococcus faecalis, and Enterococcus faecium. J Clin Microbiol (2009) 0.78
Cyclization of disulfide-containing peptides in solid-phase synthesis. Int J Pept Protein Res (1991) 0.78
Correlation of regional brain metabolism with receptor localization during ketamine anesthesia: combined autoradiographic 2-[3H]deoxy-D-glucose receptor binding technique. Proc Natl Acad Sci U S A (1982) 0.78
Altered metabolic activity in the cerebral cortex of rats exposed to ketamine. J Comp Neurol (1983) 0.77
Gonadal steroid hormones upregulate medial preoptic mu-opioid receptors in the rat. Eur J Pharmacol (1995) 0.77
Inhibition of nitric oxide synthase in the ventral tegmental area attenuates cocaine sensitization in rats. Prog Neuropsychopharmacol Biol Psychiatry (2000) 0.77
Sterically hindered C(alpha, alpha)-disubstituted alpha-amino acids: synthesis from alpha-nitroacetate and incorporation into peptides. J Org Chem (2001) 0.77
Expression of mu-opioid receptor mRNA in the medial preoptic area of juvenile rats. Brain Res Dev Brain Res (2000) 0.77
Parity-associated alterations of medial preoptic opiate receptors in female rats. Brain Res (1992) 0.77
Delta 9-tetrahydrocannabinol alters cerebral metabolism in a biphasic, dose-dependent manner in rat brain. Eur J Pharmacol (1991) 0.77
Digestion and absorption in the duodenum in relation to gastric emptying in patients with peptic ulcer before and after partial gastrectomy or selective proximal vagotomy. Scand J Gastroenterol (1974) 0.76
Effects of 1,3-di-o-tolylguanidine (DTG), a sigma ligand, on local cerebral glucose utilization in rat brain. Brain Res (1992) 0.76
Cocaine-induced sensitization of metabolic activity in extrapyramidal circuits involves prior dopamine D1-like receptor stimulation. J Pharmacol Exp Ther (1996) 0.76
Gonadal steroid hormone-dependence of beta-endorphin-like immunoreactivity in the medial preoptic area of the rat. Brain Res (1995) 0.76
Amphipathic control of the 3(10)-/alpha-helix equilibrium in synthetic peptides. J Pept Res (2001) 0.76
Pretreatment with a dopamine D1-receptor antagonist prevents metabolic activation by cocaine. Neurosci Lett (1995) 0.76
The sex hormone-dependent development of opiate receptors in the rat medial preoptic area. Brain Res (1985) 0.76
Peptides with indirect in vivo activity against an intracellular pathogen: selective lysis of infected macrophages. J Pept Res (2002) 0.76