Published in J Interv Cardiol on December 01, 1995
Spectrum of mutations in long-QT syndrome genes. KVLQT1, HERG, SCN5A, KCNE1, and KCNE2. Circulation (2000) 7.50
Genotype-phenotype correlation in the long-QT syndrome: gene-specific triggers for life-threatening arrhythmias. Circulation (2001) 7.47
Positional cloning of a novel potassium channel gene: KVLQT1 mutations cause cardiac arrhythmias. Nat Genet (1996) 7.35
Effectiveness and limitations of beta-blocker therapy in congenital long-QT syndrome. Circulation (2000) 5.09
Long QT syndrome patients with mutations of the SCN5A and HERG genes have differential responses to Na+ channel blockade and to increases in heart rate. Implications for gene-specific therapy. Circulation (1995) 4.48
The long QT syndrome. Prospective longitudinal study of 328 families. Circulation (1991) 3.99
ECG T-wave patterns in genetically distinct forms of the hereditary long QT syndrome. Circulation (1995) 3.79
The long Q-T syndrome. Am Heart J (1975) 3.75
Influence of genotype on the clinical course of the long-QT syndrome. International Long-QT Syndrome Registry Research Group. N Engl J Med (1998) 3.41
QT interval prolongation as predictor of sudden death in patients with myocardial infarction. Circulation (1978) 3.32
Low penetrance in the long-QT syndrome: clinical impact. Circulation (1999) 3.14
Proposed diagnostic criteria for the Brugada syndrome. Eur Heart J (2002) 3.01
Spectrum of ST-T-wave patterns and repolarization parameters in congenital long-QT syndrome: ECG findings identify genotypes. Circulation (2000) 2.95
Task Force on Sudden Cardiac Death of the European Society of Cardiology. Eur Heart J (2001) 2.93
Left cardiac sympathetic denervation in the therapy of congenital long QT syndrome. A worldwide report. Circulation (1991) 2.87
Clinical and genetic heterogeneity of right bundle branch block and ST-segment elevation syndrome: A prospective evaluation of 52 families. Circulation (2000) 2.81
Exercise training confers anticipatory protection from sudden death during acute myocardial ischemia. Circulation (1994) 2.79
Multiple mechanisms in the long-QT syndrome. Current knowledge, gaps, and future directions. The SADS Foundation Task Force on LQTS. Circulation (1996) 2.70
Idiopathic long QT syndrome: progress and questions. Am Heart J (1985) 2.59
Age- and sex-related differences in clinical manifestations in patients with congenital long-QT syndrome: findings from the International LQTS Registry. Circulation (1998) 2.53
Baroreflex sensitivity and heart rate variability in the identification of patients at risk for life-threatening arrhythmias: implications for clinical trials. Circulation (2001) 2.50
Vagal stimulation and prevention of sudden death in conscious dogs with a healed myocardial infarction. Circ Res (1991) 2.41
A circadian signal of change of season in patients with seasonal affective disorder. Arch Gen Psychiatry (2001) 2.32
Pathophysiology and prevention of atrial fibrillation. Circulation (2001) 2.31
Cardiac sodium channel mutations in patients with long QT syndrome, an inherited cardiac arrhythmia. Hum Mol Genet (1995) 2.30
Multiple mechanisms of Na+ channel--linked long-QT syndrome. Circ Res (1996) 2.29
A common polymorphism associated with antibiotic-induced cardiac arrhythmia. Proc Natl Acad Sci U S A (2000) 2.26
Gene-specific response of dynamic ventricular repolarization to sympathetic stimulation in LQT1, LQT2 and LQT3 forms of congenital long QT syndrome. Eur Heart J (2002) 2.17
Electrical alternation of the T-wave: clinical and experimental evidence of its relationship with the sympathetic nervous system and with the long Q-T syndrome. Am Heart J (1975) 2.03
A molecular link between the sudden infant death syndrome and the long-QT syndrome. N Engl J Med (2000) 2.02
A sympathetic reflex elicited by experimental coronary occlusion. Am J Physiol (1969) 1.89
Relation between ventricular repolarization duration and cardiac cycle length during 24-hour Holter recordings. Findings in normal patients and patients with long QT syndrome. Circulation (1992) 1.86
Inherited Brugada and long QT-3 syndrome mutations of a single residue of the cardiac sodium channel confer distinct channel and clinical phenotypes. J Biol Chem (2001) 1.78
The long QT syndrome: a prospective international study. Circulation (1985) 1.77
Evidence for a cardiac ion channel mutation underlying drug-induced QT prolongation and life-threatening arrhythmias. J Cardiovasc Electrophysiol (2000) 1.74
The elusive link between LQT3 and Brugada syndrome: the role of flecainide challenge. Circulation (2000) 1.72
Novel arrhythmogenic mechanism revealed by a long-QT syndrome mutation in the cardiac Na(+) channel. Circ Res (2001) 1.72
Electrocardiographic prediction of abnormal genotype in congenital long QT syndrome: experience in 101 related family members. J Cardiovasc Electrophysiol (2001) 1.71
Baroreflex sensitivity, clinical correlates, and cardiovascular mortality among patients with a first myocardial infarction. A prospective study. Circulation (1988) 1.67
Molecular diagnosis in a child with sudden infant death syndrome. Lancet (2001) 1.66
Autonomic mechanisms in ventricular fibrillation induced by myocardial ischemia during exercise in dogs with healed myocardial infarction. An experimental preparation for sudden cardiac death. Circulation (1984) 1.63
Baroreceptor reflex control of heart rate: a predictor of sudden cardiac death. Circulation (1982) 1.61
Gene-specific differences in the circadian variation of ventricular repolarization in the long QT syndrome: a key to sudden death during sleep? Ital Heart J (2000) 1.59
Two long QT syndrome loci map to chromosomes 3 and 7 with evidence for further heterogeneity. Nat Genet (1994) 1.55
New mutations in the KVLQT1 potassium channel that cause long-QT syndrome. Circulation (1998) 1.53
Effects of unilateral cardiac sympathetic denervation on the ventricular fibrillation threshold. Am J Cardiol (1976) 1.53
Dispersion of the QT interval. A marker of therapeutic efficacy in the idiopathic long QT syndrome. Circulation (1994) 1.51
Do increases in markers of vagal activity imply protection from sudden death? The case of scopolamine. Circulation (1995) 1.48
Inferior vena cava loop of the implantable cardioverter defibrillator endocardial lead: a possible solution of the growth problem in pediatric implantation. Pacing Clin Electrophysiol (2000) 1.48
Genetic and molecular basis of cardiac arrhythmias: impact on clinical management parts I and II. Circulation (1999) 1.44
The QT interval throughout the first 6 months of life: a prospective study. Circulation (1982) 1.43
Comparison between invasive and non-invasive measurements of baroreflex sensitivity; implications for studies on risk stratification after a myocardial infarction. Eur Heart J (2000) 1.43
Cellular dysfunction of LQT5-minK mutants: abnormalities of IKs, IKr and trafficking in long QT syndrome. Hum Mol Genet (1999) 1.43
Unexpected interaction between beta-adrenergic blockade and heart rate variability before and after myocardial infarction. A longitudinal study in dogs at high and low risk for sudden death. Circulation (1994) 1.41
Brugada syndrome and sudden cardiac death in children. Lancet (2000) 1.40
Influence of pregnancy on the risk for cardiac events in patients with hereditary long QT syndrome. LQTS Investigators. Circulation (1998) 1.39
Cardiac sympathetic innervation and the sudden infant death syndrome. A possible pathogenetic link. Am J Med (1976) 1.38
The phototherapy light visor: more to it than meets the eye. Am J Psychiatry (1995) 1.38
Nervous activity of afferent cardiac sympathetic fibres with atrial and ventricular endings. J Physiol (1973) 1.35
The idiopathic long QT syndrome: pathogenetic mechanisms and therapy. Eur Heart J (1985) 1.30
Left stellectomy in the prevention of ventricular fibrillation caused by acute myocardial ischemia in conscious dogs with anterior myocardial infarction. Circulation (1980) 1.30
Genetic and molecular basis of cardiac arrhythmias; impact on clinical management. Study group on molecular basis of arrhythmias of the working group on arrhythmias of the european society of cardiology. Eur Heart J (1999) 1.29
Comparison of clinical and genetic variables of cardiac events associated with loud noise versus swimming among subjects with the long QT syndrome. Am J Cardiol (1999) 1.25
Mechanisms of I(Ks) suppression in LQT1 mutants. Am J Physiol Heart Circ Physiol (2000) 1.24
Protective effect of vagal stimulation on reperfusion arrhythmias in cats. Circ Res (1987) 1.20
Differential response to Na+ channel blockade, beta-adrenergic stimulation, and rapid pacing in a cellular model mimicking the SCN5A and HERG defects present in the long-QT syndrome. Circ Res (1996) 1.19
Effects of unilateral stellectomy upon cardiac performance during exercise in dogs. Circ Res (1979) 1.19
Scopolamine increases vagal tone and vagal reflexes in patients after myocardial infarction. J Am Coll Cardiol (1993) 1.18
A cardiocardiac sympathovagal reflex in the cat. Circ Res (1973) 1.17
Efficacy of permanent pacing in the management of high-risk patients with long QT syndrome. Circulation (1991) 1.15
Evaluation of the spatial aspects of T-wave complexity in the long-QT syndrome. Circulation (1997) 1.15
Gender and the relationship between ventricular repolarization and cardiac cycle length during 24-h Holter recordings. Eur Heart J (1997) 1.15