M Hewison

Author PubWeight™ 64.01‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Extrarenal expression of 25-hydroxyvitamin d(3)-1 alpha-hydroxylase. J Clin Endocrinol Metab 2001 4.47
2 Local and systemic glucocorticoid metabolism in inflammatory arthritis. Ann Rheum Dis 2008 1.86
3 Expression of 25-hydroxyvitamin D3-1alpha-hydroxylase in the human kidney. J Am Soc Nephrol 1999 1.47
4 Measurement of vitamin D levels in inflammatory bowel disease patients reveals a subset of Crohn's disease patients with elevated 1,25-dihydroxyvitamin D and low bone mineral density. Gut 2004 1.43
5 Extrarenal expression of the 25-hydroxyvitamin D-1-hydroxylase. Arch Biochem Biophys 2012 1.41
6 Vitamin D induces innate antibacterial responses in human trophoblasts via an intracrine pathway. Biol Reprod 2008 1.37
7 Evidence for auto/paracrine actions of vitamin D in bone: 1alpha-hydroxylase expression and activity in human bone cells. FASEB J 2006 1.31
8 Differentiation of adipose stromal cells: the roles of glucocorticoids and 11beta-hydroxysteroid dehydrogenase. Endocrinology 1999 1.29
9 Vitamin D, the placenta and pregnancy. Arch Biochem Biophys 2011 1.28
10 Regulation of expression of 11beta-hydroxysteroid dehydrogenase type 1 in adipose tissue: tissue-specific induction by cytokines. Endocrinology 2001 1.24
11 Reduced placental 11beta-hydroxysteroid dehydrogenase type 2 mRNA levels in human pregnancies complicated by intrauterine growth restriction: an analysis of possible mechanisms. J Clin Endocrinol Metab 2001 1.21
12 Dendritic cells from human tissues express receptors for the immunoregulatory vitamin D3 metabolite, dihydroxycholecalciferol. Immunology 1987 1.20
13 Regulation of human tonsillar T-cell proliferation by the active metabolite of vitamin D3. Immunology 1986 1.19
14 Expression of 11beta-hydroxysteroid dehydrogenase type 1 in adipose tissue is not increased in human obesity. J Clin Endocrinol Metab 2002 1.17
15 Candidate 56 and 58 kDa protein(s) responsible for mediating the renal defects in oncogenic hypophosphatemic osteomalacia. Bone 1996 1.13
16 Expression of type 2 11beta-hydroxysteroid dehydrogenase and corticosteroid hormone receptors in early human fetal life. J Clin Endocrinol Metab 1998 1.13
17 Glucocorticoid activity, inactivity and the osteoblast. J Endocrinol 1999 1.11
18 Modulation of 11beta-hydroxysteroid dehydrogenase isozymes by proinflammatory cytokines in osteoblasts: an autocrine switch from glucocorticoid inactivation to activation. J Bone Miner Res 2001 1.11
19 Loss of estrogen inactivation in colonic cancer. J Clin Endocrinol Metab 1999 1.06
20 11beta-Hydroxysteroid dehydrogenase expression and glucocorticoid synthesis are directed by a molecular switch during osteoblast differentiation. Mol Endocrinol 2004 1.05
21 Splice variants of the CYP27b1 gene and the regulation of 1,25-dihydroxyvitamin D3 production. Endocrinology 2007 1.03
22 Two mutations in the hormone binding domain of the vitamin D receptor cause tissue resistance to 1,25 dihydroxyvitamin D3. J Clin Invest 1993 1.00
23 Mutations in the vitamin D receptor gene in three kindreds associated with hereditary vitamin D resistant rickets. J Clin Endocrinol Metab 1997 1.00
24 Abnormal expression of 11 beta-hydroxysteroid dehydrogenase type 2 in human pituitary adenomas: a prereceptor determinant of pituitary cell proliferation. Oncogene 2003 0.99
25 Intermittent hypercalcaemia and vitamin D sensitivity in Hodgkin's disease. Postgrad Med J 1990 0.99
26 Expression and functional consequences of 11beta-hydroxysteroid dehydrogenase activity in human bone. Bone 2000 0.97
27 11beta-hydroxysteroid dehydrogenases, cell proliferation and malignancy. J Steroid Biochem Mol Biol 2003 0.96
28 Expression and putative role of 11 beta-hydroxysteroid dehydrogenase isozymes within the human eye. Invest Ophthalmol Vis Sci 2001 0.95
29 Functional expression, characterization, and purification of the catalytic domain of human 11-beta -hydroxysteroid dehydrogenase type 1. J Biol Chem 2001 0.93
30 Estrone potentiates myeloid cell differentiation: a role for 17 beta-hydroxysteroid dehydrogenase in modulating hemopoiesis. Exp Hematol 1999 0.93
31 Expression of 25-hydroxyvitamin D3-1alpha-hydroxylase in subcutaneous fat necrosis. Br J Dermatol 2008 0.93
32 Expression of 25-hydroxyvitamin D3-1alpha-hydroxylase along the nephron: new insights into renal vitamin D metabolism. Curr Opin Nephrol Hypertens 2000 0.92
33 Estradiol formation by human osteoblasts via multiple pathways: relation with osteoblast function. J Cell Biochem 1999 0.91
34 Synergistic induction of local glucocorticoid generation by inflammatory cytokines and glucocorticoids: implications for inflammation associated bone loss. Ann Rheum Dis 2009 0.90
35 Characterization of 11beta-hydroxysteroid dehydrogenase activity and corticosteroid receptor expression in human osteosarcoma cell lines. J Endocrinol 1999 0.90
36 Vitamin D-dependent rickets type II in a cat. J Small Anim Pract 2005 0.89
37 Presentation of a PTHrP-secreting pancreatic neuroendocrine tumour, with hypercalcaemic crisis, pre-eclampsia, and renal failure. Postgrad Med J 2002 0.89
38 Constitutive expression of 25-hydroxyvitamin D3-1alpha-hydroxylase in a transformed human proximal tubule cell line: evidence for direct regulation of vitamin D metabolism by calcium. Endocrinology 1999 0.88
39 Identification of a novel mutation in hereditary vitamin D resistant rickets causing exon skipping. Clin Endocrinol (Oxf) 1996 0.88
40 Estrogen metabolism and malignancy: analysis of the expression and function of 17beta-hydroxysteroid dehydrogenases in colonic cancer. Mol Cell Endocrinol 2001 0.86
41 Regulation of 11 beta-hydroxysteroid dehydrogenase type 1 in primary cultures of rat and human hepatocytes. J Endocrinol 1998 0.86
42 Two mutations causing vitamin D resistant rickets: modelling on the basis of steroid hormone receptor DNA-binding domain crystal structures. Clin Endocrinol (Oxf) 1994 0.86
43 Association studies between microsatellite markers within the gene encoding human 11beta-hydroxysteroid dehydrogenase type 1 and body mass index, waist to hip ratio, and glucocorticoid metabolism. J Clin Endocrinol Metab 2002 0.86
44 Vitamin D and hematopoiesis. Trends Endocrinol Metab 1997 0.85
45 The renal function of 25-hydroxyvitamin D3-1alpha-hydroxylase. Mol Cell Endocrinol 1999 0.84
46 1,25-dihydroxyvitamin D3 regulates estrogen metabolism in cultured keratinocytes. Endocrinology 1997 0.83
47 Effects of 1,25-dihydroxyvitamin D3 and cortisol on bovine and human parathyroid cells. J Endocrinol 1989 0.82
48 Regulation of vitamin D-1alpha-hydroxylase in a human cortical collecting duct cell line. Kidney Int 2001 0.82
49 1,25(OH)2D3 regulates c-myc mRNA levels in tonsillar T lymphocytes. Immunology 1991 0.82
50 Progesterone is extensively metabolized in osteoblasts: implications for progesterone action on bone. Horm Metab Res 2008 0.81
51 Immunodetection of 11 beta-hydroxysteroid dehydrogenase type 2 in human mineralocorticoid target tissues: evidence for nuclear localization. Endocrinology 1997 0.81
52 Binding of the receptor for 1,25-dihydroxyvitamin D3 to the 5'-flanking region of the bovine parathyroid hormone gene. J Endocrinol 1990 0.79
53 Expression of 11 beta-hydroxysteroid dehydrogenase in rat osteoblastic cells: pre-receptor regulation of glucocorticoid responses in bone. J Cell Biochem 2001 0.79
54 Oestrogen inactivation in the colon: analysis of the expression and regulation of 17beta-hydroxysteroid dehydrogenase isozymes in normal colon and colonic cancer. Br J Cancer 2000 0.78
55 Co-chaperone potentiation of vitamin D receptor-mediated transactivation: a role for Bcl2-associated athanogene-1 as an intracellular-binding protein for 1,25-dihydroxyvitamin D3. J Mol Endocrinol 2007 0.78
56 Clofibric acid: a potential therapeutic agent in AML and MDS. Br J Haematol 1999 0.78
57 Expression of 11 beta-hydroxysteroid dehydrogenase isozymes and corticosteroid hormone receptors in primary cultures of human trophoblast and placental bed biopsies. Mol Hum Reprod 2001 0.77
58 Characterization of aromatase and 17 beta-hydroxysteroid dehydrogenase expression in rat osteoblastic cells. J Bone Miner Res 1998 0.77
59 Differential RNA display identifies novel genes associated with decreased vitamin D receptor expression. Mol Cell Endocrinol 1998 0.77
60 Selenium and heavy metals. Ann Clin Res 1986 0.77
61 Differential expression of nuclear 11beta-hydroxysteroid dehydrogenase type 2 in mineralocorticoid receptor positive and negative tissues. Endocrinology 1997 0.76
62 Characterization of human trophoblast as a mineralocorticoid target tissue. Mol Hum Reprod 2003 0.76
63 Steroid hormone metabolites and hormone binding assays. Methods Mol Biol 2001 0.75
64 Cell mates in the superfamily. Endocrinology 1994 0.75