Published in J Am Soc Nephrol on December 01, 1999
Genetic evidence that the human CYP2R1 enzyme is a key vitamin D 25-hydroxylase. Proc Natl Acad Sci U S A (2004) 2.89
Plasma 25-hydroxyvitamin D levels and risk of incident hypertension among young women. Hypertension (2008) 2.81
Respiratory epithelial cells convert inactive vitamin D to its active form: potential effects on host defense. J Immunol (2008) 2.70
Implications of vitamin D deficiency in pregnancy and lactation. Am J Obstet Gynecol (2009) 1.76
The ontogeny of 25-hydroxyvitamin D(3) 1alpha-hydroxylase expression in human placenta and decidua. Am J Pathol (2002) 1.41
Aberrant Phex function in osteoblasts and osteocytes alone underlies murine X-linked hypophosphatemia. J Clin Invest (2008) 1.38
Vitamin D induces innate antibacterial responses in human trophoblasts via an intracrine pathway. Biol Reprod (2008) 1.37
Reduction of the vitamin D hormonal system in kidney disease is associated with increased renal inflammation. Kidney Int (2008) 1.36
1,25-Dihydroxyvitamin D inhibits lipopolysaccharide-induced immune activation in human endothelial cells. Clin Exp Immunol (2006) 1.22
1alpha,25-Dihydroxyvitamin D hydroxylase in adipocytes. J Steroid Biochem Mol Biol (2008) 1.19
Intestinal vitamin D receptor is required for normal calcium and bone metabolism in mice. Gastroenterology (2008) 1.15
CYP27B1 null mice with LacZreporter gene display no 25-hydroxyvitamin D3-1alpha-hydroxylase promoter activity in the skin. Proc Natl Acad Sci U S A (2005) 1.13
Vitamin D effects on lung immunity and respiratory diseases. Vitam Horm (2011) 1.12
Expression of the vitamin D-activating enzyme 1α-hydroxylase (CYP27B1) decreases during melanoma progression. Hum Pathol (2012) 1.09
VDR and CYP27B1 are expressed in C2C12 cells and regenerating skeletal muscle: potential role in suppression of myoblast proliferation. Am J Physiol Cell Physiol (2012) 1.03
25-Hydroxyvitamin D3 1alpha-hydroxylase expression in breast cancer and use of non-1alpha-hydroxylated vitamin D analogue. Breast Cancer Res (2005) 1.01
Expression of 25-hydroxyvitamin D3-1alpha-hydroxylase in subcutaneous fat necrosis. Br J Dermatol (2008) 0.93
Vitamin D metabolism: new concepts and clinical implications. Clin Biochem Rev (2003) 0.93
CYP24A1 expression inversely correlates with melanoma progression: clinic-pathological studies. Int J Mol Sci (2014) 0.88
Human male gamete endocrinology: 1alpha, 25-dihydroxyvitamin D3 (1,25(OH)2D3) regulates different aspects of human sperm biology and metabolism. Reprod Biol Endocrinol (2009) 0.87
Impaired vitamin D activation and association with CYP24A1 haplotypes in differentiated thyroid carcinoma. Thyroid (2012) 0.87
Vitamin D and the kidney. Arch Biochem Biophys (2012) 0.86
Vitamin D3 deficiency differentially affects functional and disease outcomes in the G93A mouse model of amyotrophic lateral sclerosis. PLoS One (2011) 0.85
Novel Strategies in the Prevention and Treatment of Urinary Tract Infections. Pathogens (2016) 0.83
Decreased conversion of 25-hydroxyvitamin D3 to 24,25-dihydroxyvitamin D3 following cholecalciferol therapy in patients with CKD. Clin J Am Soc Nephrol (2014) 0.83
Decreased expression of CYP27B1 correlates with the increased aggressiveness of ovarian carcinomas. Oncol Rep (2014) 0.80
Analysis of CYP27B1, encoding 25-hydroxyvitamin D-1alpha-hydroxylase, as a candidate tumor suppressor gene in primary and severe secondary/tertiary hyperparathyroidism. J Bone Miner Res (2009) 0.79
Alterations in vitamin D metabolite, parathyroid hormone and fibroblast growth factor-23 concentrations in sclerostin-deficient mice permit the maintenance of a high bone mass. J Steroid Biochem Mol Biol (2014) 0.79
Cloning of a functional 25-hydroxyvitamin D-1α-hydroxylase in zebrafish (Danio rerio). Cell Biochem Funct (2014) 0.78
Cardioprotective effects of ω -3 PUFAs in chronic kidney disease. Biomed Res Int (2013) 0.77
Reduced renal calcium excretion in the absence of sclerostin expression: evidence for a novel calcium-regulating bone kidney axis. J Am Soc Nephrol (2014) 0.76
Hypercalcemia in upper urinary tract urothelial carcinoma: a case report and literature review. Case Rep Endocrinol (2013) 0.75
Relationship of 1,25 dihydroxy Vitamin D Levels to Clinical Outcomes in Critically Ill Patients with Acute Kidney Injury. J Nephrol Ther (2015) 0.75
Checkpoint kinase Chk2 controls renal Cyp27b1 expression, calcitriol formation, and calcium-phosphate metabolism. Pflugers Arch (2014) 0.75
Extrarenal expression of 25-hydroxyvitamin d(3)-1 alpha-hydroxylase. J Clin Endocrinol Metab (2001) 4.47
Association between premature mortality and hypopituitarism. West Midlands Prospective Hypopituitary Study Group. Lancet (2001) 4.14
Spread of Streptococcus pneumoniae in families. I. Carriage rates and distribution of types. J Infect Dis (1975) 3.33
Serum free light-chain measurements for identifying and monitoring patients with nonsecretory multiple myeloma. Blood (2001) 2.93
Structure, function and properties of antibody binding sites. J Mol Biol (1991) 2.84
Treatment of adrenocorticotropin-dependent Cushing's syndrome: a consensus statement. J Clin Endocrinol Metab (2008) 2.70
Defining the normal cortisol response to the short Synacthen test: implications for the investigation of hypothalamic-pituitary disorders. Clin Endocrinol (Oxf) (1998) 2.59
Metabolism of labetalol by animals and man. Br J Clin Pharmacol (1976) 2.57
The patient-provider relationship: attachment theory and adherence to treatment in diabetes. Am J Psychiatry (2001) 2.57
Cost-effectiveness of a collaborative care program for primary care patients with persistent depression. Am J Psychiatry (2001) 2.35
Does central obesity reflect "Cushing's disease of the omentum"? Lancet (1997) 2.34
Sex differences in rates of depression: cross-national perspectives. J Affect Disord (1994) 2.25
Improved cortisol exposure-time profile and outcome in patients with adrenal insufficiency: a prospective randomized trial of a novel hydrocortisone dual-release formulation. J Clin Endocrinol Metab (2011) 2.16
Treatment of acromegaly with the growth hormone-receptor antagonist pegvisomant. N Engl J Med (2000) 2.16
Elevated cerebrospinal fluid (CSF) leptin in idiopathic intracranial hypertension (IIH): evidence for hypothalamic leptin resistance? Clin Endocrinol (Oxf) (2008) 2.15
Cloning and expression of a distinctive class of self-incompatibility (S) gene from Papaver rhoeas L. Proc Natl Acad Sci U S A (1994) 2.15
Scleroderma renal crisis: patient characteristics and long-term outcomes. QJM (2007) 2.14
Long-term treatment of acromegaly with pegvisomant, a growth hormone receptor antagonist. Lancet (2001) 2.08
Serum free light chains for monitoring multiple myeloma. Br J Haematol (2004) 2.07
ATM mutations and phenotypes in ataxia-telangiectasia families in the British Isles: expression of mutant ATM and the risk of leukemia, lymphoma, and breast cancer. Am J Hum Genet (1998) 2.06
Pseudomyxoma peritonei syndrome. Adv Surg (1996) 1.99
Localisation of 11 beta-hydroxysteroid dehydrogenase--tissue specific protector of the mineralocorticoid receptor. Lancet (1988) 1.97
Relapse of depression in primary care. Rate and clinical predictors. Arch Fam Med (1998) 1.87
Local and systemic glucocorticoid metabolism in inflammatory arthritis. Ann Rheum Dis (2008) 1.86
Localisation of tumour deposits by external scanning after injection of radiolabelled anti-carcinoembryonic antigen. Br Med J (1980) 1.82
Low plasma C4 concentrations: association with microangiopathy in insulin dependent diabetes. Br Med J (Clin Res Ed) (1984) 1.82
Achieving guidelines for the treatment of depression in primary care: is physician education enough? Med Care (1997) 1.81
A study of plasma proteins in the sol phase of sputum from patients with chronic bronchitis. Thorax (1979) 1.79
Classical versus non-renal Wegener's granulomatosis. Q J Med (1994) 1.79
A randomized, double-blind crossover trial of sertraline in women with chronic pelvic pain. J Psychosom Res (1998) 1.78
Can enhanced acute-phase treatment of depression improve long-term outcomes? A report of randomized trials in primary care. Am J Psychiatry (1999) 1.77
Renal pathological findings in infective endocarditis. Nephrol Dial Transplant (2000) 1.74
Identification of susceptibility loci for insulin-dependent diabetes mellitus by trans-racial gene mapping. Nature (1989) 1.64
Medically unexplained symptoms in primary care. J Clin Psychiatry (1998) 1.64
Effect of carbon dioxide in acute mountain sickness: a rediscovery. Lancet (1988) 1.64
Mineralocorticoid excess and inhibition of 11 beta-hydroxysteroid dehydrogenase in patients with ectopic ACTH syndrome. Clin Endocrinol (Oxf) (1992) 1.56
Quantitative analysis of serum free light chains. A new marker for the diagnostic evaluation of primary systemic amyloidosis. Am J Clin Pathol (2003) 1.55
Increased prevalence of renal biopsy findings other than diabetic glomerulopathy in type II diabetes mellitus. Nephrol Dial Transplant (1992) 1.54
Non-steroidal anti-inflammatory drugs and renal failure. Lancet (1986) 1.52
Protein repletion and treatment in anorexia nervosa. Am J Clin Nutr (1994) 1.50
Mineralocorticoid hypertension and congenital deficiency of 11 beta-hydroxysteroid dehydrogenase in a family with the syndrome of 'apparent' mineralocorticoid excess. Clin Endocrinol (Oxf) (1995) 1.44
Suppression of uninvolved immunoglobulins defined by heavy/light chain pair suppression is a risk factor for progression of MGUS. Leukemia (2012) 1.44
Depression after childbirth. J Am Board Fam Pract (1992) 1.42
Extrarenal expression of the 25-hydroxyvitamin D-1-hydroxylase. Arch Biochem Biophys (2012) 1.41
Association of vasculitic glomerulonephritis with membranous nephropathy: a report of 10 cases. Nephrol Dial Transplant (1997) 1.41
Diagnosis and treatment of thyroid nodules and goitre. J R Coll Physicians Lond (1998) 1.38
Vitamin D induces innate antibacterial responses in human trophoblasts via an intracrine pathway. Biol Reprod (2008) 1.37
Effect of dose, molecular size, affinity, and protein binding on tumor uptake of antibody or ligand: a biomathematical model. Cancer Res (1989) 1.35
Measurements of medication adherence in diabetic patients with poorly controlled HbA(1c). Diabet Med (2010) 1.35
Radioimmunotherapy of cancer: clinical studies and limiting factors. Cancer Treat Rev (1987) 1.31
Evidence for auto/paracrine actions of vitamin D in bone: 1alpha-hydroxylase expression and activity in human bone cells. FASEB J (2006) 1.31
The relationship between albuminuria, MCP-1/CCL2, and interstitial macrophages in chronic kidney disease. Kidney Int (2006) 1.30
1alpha-Hydroxylase and the action of vitamin D. J Mol Endocrinol (2000) 1.30
Differentiation of adipose stromal cells: the roles of glucocorticoids and 11beta-hydroxysteroid dehydrogenase. Endocrinology (1999) 1.29
The clinical assessment of acute mountain sickness. Q J Med (1985) 1.28
Family violence and psychiatric disorder. Can J Psychiatry (1986) 1.28
Vitamin D, the placenta and pregnancy. Arch Biochem Biophys (2011) 1.28
The effect of health education on the rate of ophthalmic examinations among African Americans with diabetes mellitus. Am J Public Health (1999) 1.28
Assessing the ethical costs and benefits of trauma-focused research. Gen Hosp Psychiatry (1999) 1.27
Relapses in patients with a systemic vasculitis. Q J Med (1993) 1.27
Short term regulation of ureagenesis. J Biol Chem (1980) 1.26
Pituitary tumor transforming gene and fibroblast growth factor-2 expression: potential prognostic indicators in differentiated thyroid cancer. J Clin Endocrinol Metab (2003) 1.24
Regulation of expression of 11beta-hydroxysteroid dehydrogenase type 1 in adipose tissue: tissue-specific induction by cytokines. Endocrinology (2001) 1.24
Urinary free cortisone and the assessment of 11 beta-hydroxysteroid dehydrogenase activity in man. Clin Endocrinol (Oxf) (1996) 1.23
Immunohistochemical localization of type 1 11beta-hydroxysteroid dehydrogenase in human tissues. J Clin Endocrinol Metab (1998) 1.23
The effect of acetazolamide on the proteinuria of altitude. Aviat Space Environ Med (1982) 1.23
Controlled trial of pulse versus continuous prednisolone and cyclophosphamide in the treatment of systemic vasculitis. QJM (1997) 1.22
Ophthalmic referral rates for patients with diabetes in primary-care clinics located in disadvantaged urban communities. J Diabetes Complications (1995) 1.22
Altitude insomnia: studies during an expedition to the Himalayas. Sleep (1988) 1.21
Reduced placental 11beta-hydroxysteroid dehydrogenase type 2 mRNA levels in human pregnancies complicated by intrauterine growth restriction: an analysis of possible mechanisms. J Clin Endocrinol Metab (2001) 1.21
Knowledge of renal histology alters patient management in over 40% of cases. Nephrol Dial Transplant (1994) 1.20
Scanning and transmission electron microscopy on the epithelium of human palatine tonsils. J Pathol (1980) 1.20
Dendritic cells from human tissues express receptors for the immunoregulatory vitamin D3 metabolite, dihydroxycholecalciferol. Immunology (1987) 1.20
Regulation of human tonsillar T-cell proliferation by the active metabolite of vitamin D3. Immunology (1986) 1.19
Internal jugular phlebectasia. A clinicoroentgenographic diagnosis. Arch Otolaryngol (1976) 1.19
Primary medical therapy for acromegaly: an open, prospective, multicenter study of the effects of subcutaneous and intramuscular slow-release octreotide on growth hormone, insulin-like growth factor-I, and tumor size. J Clin Endocrinol Metab (2002) 1.18
Growth hormone and pituitary radiotherapy, but not serum insulin-like growth factor-I concentrations, predict excess mortality in patients with acromegaly. J Clin Endocrinol Metab (2004) 1.18
11Beta-hydroxysteroid dehydrogenase type 2 in human pregnancy and reduced expression in intrauterine growth restriction. Hum Reprod (1998) 1.18
Expression of 11beta-hydroxysteroid dehydrogenase type 1 in adipose tissue is not increased in human obesity. J Clin Endocrinol Metab (2002) 1.17
Polyarteritis and the kidney. Q J Med (1987) 1.16
An optical practice based diabetic eye screening programme. Diabet Med (1995) 1.16
Widespread distribution in human tissues of an antigenic determinant of granulocytes. J Clin Pathol (1984) 1.15
Candidate 56 and 58 kDa protein(s) responsible for mediating the renal defects in oncogenic hypophosphatemic osteomalacia. Bone (1996) 1.13
Psychiatric manifestations of multiple sclerosis: a review. Can J Psychiatry (1996) 1.13
Expression of type 2 11beta-hydroxysteroid dehydrogenase and corticosteroid hormone receptors in early human fetal life. J Clin Endocrinol Metab (1998) 1.13