Published in J Biol Chem on October 25, 1976
Purification of cachectin, a lipoprotein lipase-suppressing hormone secreted by endotoxin-induced RAW 264.7 cells. J Exp Med (1985) 8.18
Lipoprotein lipase suppression in 3T3-L1 cells by an endotoxin-induced mediator from exudate cells. Proc Natl Acad Sci U S A (1982) 3.69
CCAAT/enhancer binding protein alpha is sufficient to initiate the 3T3-L1 adipocyte differentiation program. Proc Natl Acad Sci U S A (1994) 3.66
Mouse insulin-responsive glucose transporter gene: characterization of the gene and trans-activation by the CCAAT/enhancer binding protein. Proc Natl Acad Sci U S A (1990) 3.05
Expression of specific mRNAs during adipose differentiation: identification of an mRNA encoding a homologue of myelin P2 protein. Proc Natl Acad Sci U S A (1984) 2.98
Sequence, tissue distribution, and differential expression of mRNA for a putative insulin-responsive glucose transporter in mouse 3T3-L1 adipocytes. Proc Natl Acad Sci U S A (1989) 2.69
Induction of caveolin during adipogenesis and association of GLUT4 with caveolin-rich vesicles. J Cell Biol (1994) 2.69
Organelle relationships in cultured 3T3-L1 preadipocytes. J Cell Biol (1980) 2.30
Type beta transforming growth factor controls the adipogenic differentiation of 3T3 fibroblasts. Proc Natl Acad Sci U S A (1985) 2.28
Enforced expression of the c-myc oncogene inhibits cell differentiation by precluding entry into a distinct predifferentiation state in G0/G1. Mol Cell Biol (1988) 2.08
Alterations in insulin binding accompanying differentiation of 3T3-L1 preadipocytes. Proc Natl Acad Sci U S A (1977) 2.01
A study of the adipose conversion of suspended 3T3 cells by using glycerophosphate dehydrogenase as differentiation marker. Proc Natl Acad Sci U S A (1979) 1.94
Insulin receptor synthesis and turnover in differentiating 3T3-L1 preadipocytes. Proc Natl Acad Sci U S A (1980) 1.82
Adipose conversion of 3T3 cells depends on a serum factor. Proc Natl Acad Sci U S A (1978) 1.82
Functional and pathological roles of the 12- and 15-lipoxygenases. Prog Lipid Res (2010) 1.72
Selective inhibition of synthesis of enzymes for de novo fatty acid biosynthesis by an endotoxin-induced mediator from exudate cells. Proc Natl Acad Sci U S A (1983) 1.68
Insulin-treated 3T3-L1 adipocytes and cell-free extracts derived from them incorporate 32P into ribosomal protein S6. Proc Natl Acad Sci U S A (1980) 1.53
Regulation of glutamine synthetase in cultured 3T3-L1 cells by insulin, hydrocortisone, and dibutyryl cyclic AMP. Proc Natl Acad Sci U S A (1978) 1.45
Establishment of preadipocyte clonal line from epididymal fat pad of ob/ob mouse that responds to insulin and to lipolytic hormones. Proc Natl Acad Sci U S A (1978) 1.43
Insulin-stimulated protein phosphorylation in 3T3-L1 preadipocytes. Proc Natl Acad Sci U S A (1979) 1.41
Expression of the differentiation-induced gene for fatty acid-binding protein is activated by glucocorticoid and cAMP. Proc Natl Acad Sci U S A (1988) 1.40
Recombinant human cachectin/tumor necrosis factor but not interleukin-1 alpha downregulates lipoprotein lipase gene expression at the transcriptional level in mouse 3T3-L1 adipocytes. Mol Cell Biol (1988) 1.35
Hormone-sensitive lipase in differentiated 3T3-L1 cells and its activation by cyclic AMP-dependent protein kinase. Proc Natl Acad Sci U S A (1981) 1.29
Role of calpain in adipocyte differentiation. Proc Natl Acad Sci U S A (1999) 1.26
The peroxisome proliferator-activated receptor-gamma regulates murine pyruvate carboxylase gene expression in vivo and in vitro. J Biol Chem (2005) 1.23
IFATS collection: Combinatorial peptides identify alpha5beta1 integrin as a receptor for the matricellular protein SPARC on adipose stromal cells. Stem Cells (2008) 1.16
Functional analysis of long-chain acyl-CoA synthetase 1 in 3T3-L1 adipocytes. J Biol Chem (2009) 1.14
Induction of pyruvate carboxylase apoenzyme and holoenzyme in 3T3-L1 cells during differentiation. Proc Natl Acad Sci U S A (1980) 1.09
Adipogenic and anti-adipogenic factors in the pituitary and other organs. Proc Natl Acad Sci U S A (1981) 1.04
ATP citrate-lyase and glycogen synthase kinase-3 beta in 3T3-L1 cells during differentiation into adipocytes. Biochem J (1994) 1.00
Antibody-induced desensitization of the insulin receptor. Studies of the mechanism of desensitization in 3T3-L1 fatty fibroblasts. J Clin Invest (1980) 0.99
Increase in fatty acid synthetase content of 3T3-L cells undergoing spontaneous and chemically induced differentiation to adipocytes. Biochem J (1979) 0.96
Distribution and degradation of biotin-containing carboxylases in human cell lines. Biochem J (1985) 0.96
Multiple biotin-containing proteins in 3T3-L1 cells. Biochem J (1986) 0.96
Adipose tissues and thyroid hormones. Front Physiol (2014) 0.96
Interferon inhibits the conversion of 3T3-L1 mouse fibroblasts into adipocytes. Proc Natl Acad Sci U S A (1980) 0.95
Functional expression of a Delta12 fatty acid desaturase gene from spinach in transgenic pigs. Proc Natl Acad Sci U S A (2004) 0.94
Adipose pyruvate carboxylase: amino acid sequence and domain structure deduced from cDNA sequencing. Proc Natl Acad Sci U S A (1993) 0.93
Induction of acyl-CoA-binding protein and its mRNA in 3T3-L1 cells by insulin during preadipocyte-to-adipocyte differentiation. Biochem J (1991) 0.93
Protein kinase C isoforms play differential roles in the regulation of adipocyte differentiation. Biochem J (1998) 0.93
Studies of insulin resistance in adipocytes induced by macrophage mediator. J Exp Med (1983) 0.93
Inhibition of pyruvate carboxylase degradation and total protein breakdown by lysosomotropic agents in 3T3-L1 cells. Biochem J (1983) 0.91
Role of glycosylation and protein synthesis in insulin receptor metabolism by 3T3-L1 mouse adipocytes. Proc Natl Acad Sci U S A (1981) 0.87
The changing balance between osteoblastogenesis and adipogenesis in aging and its impact on hematopoiesis. Curr Osteoporos Rep (2013) 0.86
Regulation of lipoprotein lipase synthesis in 3T3-L1 adipocytes by cachectin. Further proof for identity with tumour necrosis factor. Biochem J (1986) 0.84
Regulation of pyruvate carboxylase in 3T3-L1 cells. Biochem J (1995) 0.84
3T3-L1 adipocytes display phenotypic characteristics of multiple adipocyte lineages. Adipocyte (2015) 0.82
Uptake and binding of radiolabelled phenylarsine oxide in 3T3-L1 adipocytes. Biochem J (1990) 0.82
Induction of dihydrolipoamide dehydrogenase in 3T3-L1 cells during differentiation. Biochem J (1988) 0.81
Identification of a novel integral plasma membrane protein induced during adipocyte differentiation. Biochem J (2001) 0.79
Regulation of FAT/CD36 mRNA gene expression by long chain fatty acids in the differentiated 3T3-L1 cells. Pediatr Surg Int (2007) 0.78
Dual Regulatory Role of Polyamines in Adipogenesis. J Biol Chem (2015) 0.78
Lipid Profiling of In Vitro Cell Models of Adipogenic Differentiation: Relationships With Mouse Adipose Tissues. J Cell Biochem (2016) 0.78
A paradox: insulin inhibits expression and secretion of resistin which induces insulin resistance. World J Gastroenterol (2008) 0.78
Development of an OP9 derived cell line as a robust model to rapidly study adipocyte differentiation. PLoS One (2014) 0.77
Modulation of lipid-synthesizing enzymes by insulin in differentiated ob17 adipose-like cells. Biochem J (1983) 0.77
Hormonal regulation of the transformation phenotype in simian virus 40-transformed rat embryonic preadipose cell lines. Mol Cell Biol (1984) 0.77
Adipocyte differentiation is affected by media height above the cell layer. Int J Obes (Lond) (2013) 0.77
Turnover of acyl-CoA-binding protein in four different cell lines measured by using two-dimensional polyacrylamide-gel electrophoresis. Biochem J (1994) 0.76
Differentiation of 3T3-L2 fibroblasts into adipose cells in bromodeoxyuridine-suppressed cultures. Proc Natl Acad Sci U S A (1979) 0.76
3T3-L1 preadipocyte differentiation and poly(ADP-ribose) synthetase. Mol Cell Biochem (1983) 0.76
Ethanol extracts of chickpeas alter the total lipid content and expression levels of genes related to fatty acid metabolism in mouse 3T3-L1 adipocytes. Int J Mol Med (2016) 0.75
Interaction between von Hippel-Lindau Protein and Fatty Acid Synthase Modulates Hypoxia Target Gene Expression. Sci Rep (2017) 0.75
Spinach ribulose diphosphate carboxylase. I. Purification and properties of the enzyme. Biochemistry (1966) 5.87
Transcriptional regulation of gene expression during adipocyte differentiation. Annu Rev Biochem (1995) 5.75
Differentiation-induced gene expression in 3T3-L1 preadipocytes: CCAAT/enhancer binding protein interacts with and activates the promoters of two adipocyte-specific genes. Genes Dev (1989) 5.59
Induction of fatty acid synthetase synthesis in differentiating 3T3-L1 preadipocytes. J Biol Chem (1980) 5.06
Reduced food intake and body weight in mice treated with fatty acid synthase inhibitors. Science (2000) 4.62
Leptin regulates proinflammatory immune responses. FASEB J (1998) 4.31
CCAAT/enhancer binding protein gene promoter: binding of nuclear factors during differentiation of 3T3-L1 preadipocytes. Proc Natl Acad Sci U S A (1991) 3.98
Obesity increases sensitivity to endotoxin liver injury: implications for the pathogenesis of steatohepatitis. Proc Natl Acad Sci U S A (1997) 3.79
Lipoprotein lipase suppression in 3T3-L1 cells by an endotoxin-induced mediator from exudate cells. Proc Natl Acad Sci U S A (1982) 3.69
CCAAT/enhancer binding protein alpha is sufficient to initiate the 3T3-L1 adipocyte differentiation program. Proc Natl Acad Sci U S A (1994) 3.66
Evidence for the involvement of vicinal sulfhydryl groups in insulin-activated hexose transport by 3T3-L1 adipocytes. J Biol Chem (1985) 3.51
Antisense CCAAT/enhancer-binding protein RNA suppresses coordinate gene expression and triglyceride accumulation during differentiation of 3T3-L1 preadipocytes. Genes Dev (1992) 3.41
A 30-kDa alternative translation product of the CCAAT/enhancer binding protein alpha message: transcriptional activator lacking antimitotic activity. Proc Natl Acad Sci U S A (1993) 3.33
Activation and centromeric localization of CCAAT/enhancer-binding proteins during the mitotic clonal expansion of adipocyte differentiation. Genes Dev (1999) 3.19
Regulation of adipocyte development. Annu Rev Nutr (1994) 3.09
Mouse insulin-responsive glucose transporter gene: characterization of the gene and trans-activation by the CCAAT/enhancer binding protein. Proc Natl Acad Sci U S A (1990) 3.05
Expression of specific mRNAs during adipose differentiation: identification of an mRNA encoding a homologue of myelin P2 protein. Proc Natl Acad Sci U S A (1984) 2.98
The enzymatic carboxylation of phosphoenolpyruvate. II. Purification and properties of liver mitochondrial phosphoenolpyruvate carboxykinase. J Biol Chem (1966) 2.89
Evidence for an increase in transcription of specific mRNAs during differentiation of 3T3-L1 preadipocytes. J Biol Chem (1985) 2.75
Differentiation-induced gene expression in 3T3-L1 preadipocytes. Characterization of a differentially expressed gene encoding stearoyl-CoA desaturase. J Biol Chem (1988) 2.73
Sequence, tissue distribution, and differential expression of mRNA for a putative insulin-responsive glucose transporter in mouse 3T3-L1 adipocytes. Proc Natl Acad Sci U S A (1989) 2.69
Differentiation-induced gene expression in 3T3-L1 preadipocytes. A second differentially expressed gene encoding stearoyl-CoA desaturase. J Biol Chem (1989) 2.47
The biotin-dependent enzymes. Adv Enzymol Relat Areas Mol Biol (1971) 2.45
Is CCAAT/enhancer-binding protein a central regulator of energy metabolism? Genes Dev (1989) 2.44
Regulating adipogenesis. J Biol Chem (1997) 2.40
The enzymatic carboxylation of phosphoenolpyruvate. I. Purification and properties of phosphoenolpyruvate carboxylase. J Biol Chem (1966) 2.20
Regulated expression of the obese gene product (leptin) in white adipose tissue and 3T3-L1 adipocytes. Proc Natl Acad Sci U S A (1995) 2.17
Synthesis, turnover, and down-regulation of epidermal growth factor receptors in human A431 epidermoid carcinoma cells and skin fibroblasts. J Biol Chem (1982) 2.10
Inhibition of ribulose diphosphate carboxylase by cyanide. Inactive ternary complex of enzyme, ribulose diphosphate, and cyanide. J Biol Chem (1969) 2.04
On the mechanism of ligand-induced down-regulation of insulin receptor level in the liver cell. J Biol Chem (1981) 2.03
Nonidentical subunits of ribulose diphosphate carboxylase. Biochem Biophys Res Commun (1967) 2.02
Alterations in insulin binding accompanying differentiation of 3T3-L1 preadipocytes. Proc Natl Acad Sci U S A (1977) 2.01
Acetyl coenzyme A carboxylase system of Escherichia coli. Purification and properties of the biotin carboxylase, carboxyltransferase, and carboxyl carrier protein components. J Biol Chem (1974) 1.99
Obesity induces expression of uncoupling protein-2 in hepatocytes and promotes liver ATP depletion. J Biol Chem (1999) 1.94
The interaction of metal ions with ribulose 1,5-diphosphate carboxylase from spinach. J Biol Chem (1970) 1.94
Acetyl coenzyme A carboxylase. Curr Top Cell Regul (1974) 1.94
Transcriptional activation of the mouse obese (ob) gene by CCAAT/enhancer binding protein alpha. Proc Natl Acad Sci U S A (1996) 1.92
Repressive effect of Sp1 on the C/EBPalpha gene promoter: role in adipocyte differentiation. Mol Cell Biol (1999) 1.90
Effect of tunicamycin on the secretion of serum proteins by primary cultures of rat and chick hepatocytes. Studies on transferrin, very low density lipoprotein, and serum albumin. J Biol Chem (1978) 1.88
Selective changes in microsomal enzymes of triacylglycerol phosphatidylcholine, and phosphatidylethanolamine biosynthesis during differentiation of 3T3-L1 preadipocytes. J Biol Chem (1978) 1.86
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Role of C/EBP homologous protein (CHOP-10) in the programmed activation of CCAAT/enhancer-binding protein-beta during adipogenesis. Proc Natl Acad Sci U S A (2000) 1.85
Insulin receptor synthesis and turnover in differentiating 3T3-L1 preadipocytes. Proc Natl Acad Sci U S A (1980) 1.82
Promoter-cDNA-directed heterologous protein expression in Xenopus laevis oocytes. Proc Natl Acad Sci U S A (1992) 1.79
Molecular characteristics of liver acetyl CoA carboxylase. Proc Natl Acad Sci U S A (1966) 1.78
Insulin regulates transcription of the CCAAT/enhancer binding protein (C/EBP) alpha, beta, and delta genes in fully-differentiated 3T3-L1 adipocytes. J Biol Chem (1995) 1.77
Liver acetyl coenzyme A carboxylase. I. Isolation and cat- alytic properties. J Biol Chem (1968) 1.74
Cell-free transcription directed by the 422 adipose P2 gene promoter: activation by the CCAAT/enhancer binding protein. Proc Natl Acad Sci U S A (1991) 1.72
Selective inhibition of synthesis of enzymes for de novo fatty acid biosynthesis by an endotoxin-induced mediator from exudate cells. Proc Natl Acad Sci U S A (1983) 1.68
Tissue specific expression of p422 protein, a putative lipid carrier, in mouse adipocytes. Biochem Biophys Res Commun (1985) 1.66
Insulin-activated tyrosine phosphorylation of a 15-kilodalton protein in intact 3T3-L1 adipocytes. Proc Natl Acad Sci U S A (1987) 1.65
A mild procedure for the rapid release of cytoplasmic enzymes from cultured animal cells. Anal Biochem (1979) 1.63
Role of glycosylation in the processing of newly translated insulin proreceptor in 3T3-L1 adipocytes. J Biol Chem (1984) 1.62
Obese gene expression at in vivo levels by fat pads derived from s.c. implanted 3T3-F442A preadipocytes. Proc Natl Acad Sci U S A (1997) 1.55
Mitotic clonal expansion during preadipocyte differentiation: calpain-mediated turnover of p27. J Biol Chem (2000) 1.55
Substrate phosphorylation catalyzed by the insulin receptor tyrosine kinase. Kinetic correlation to autophosphorylation of specific sites in the beta subunit. J Biol Chem (1989) 1.49
Glucocorticoids reciprocally regulate expression of the CCAAT/enhancer-binding protein alpha and delta genes in 3T3-L1 adipocytes and white adipose tissue. J Biol Chem (1994) 1.46
Liver acetyl CoA carboxylase and fatty acid synthetase: relative activities in the normal state and in hereditary obesity. Biochem Biophys Res Commun (1967) 1.45
Role of pyruvate carboxylase in fatty acid synthesis: alterations during preadipocyte differentiation. Biochem Biophys Res Commun (1977) 1.44
Post-translational changes in tertiary and quaternary structure of the insulin proreceptor. Correlation with acquisition of function. J Biol Chem (1988) 1.44
Expression of the differentiation-induced gene for fatty acid-binding protein is activated by glucocorticoid and cAMP. Proc Natl Acad Sci U S A (1988) 1.40
Mechanism of regulation of the 422(aP2) gene by cAMP during preadipocyte differentiation. Proc Natl Acad Sci U S A (1989) 1.36
3-Hydroxy-3-methylgutaryl-CoA synthase. Participation of acetyl-S-enzyme and enzyme-S-hydroxymethylgutaryl-SCoA intermediates in the reaction. J Biol Chem (1977) 1.35
Transcriptional repression of the mouse insulin-responsive glucose transporter (GLUT4) gene by cAMP. Proc Natl Acad Sci U S A (1991) 1.33
The enzymatic carboxylation of phosphoenolpyruvate. 3. Investigation of the kinetics and mechanism of the mitochondrial phosphoenolpyruvate carboxykinase-catalyzed reaction. J Biol Chem (1966) 1.30
Stringent control of fatty acid synthesis in Escherichia coli. Possible regulation of acetyl coenzyme A carboxylase by ppGpp. J Biol Chem (1973) 1.29
Role of calpain in adipocyte differentiation. Proc Natl Acad Sci U S A (1999) 1.26
Activation of glucose uptake by insulin and insulin-like growth factor I in Xenopus oocytes. Proc Natl Acad Sci U S A (1989) 1.26
Molecular and catalytic properties of mitochondrial (ketogenic) 3-hydroxy-3-methylglutaryl coenzyme A synthase of liver. J Biol Chem (1975) 1.24
Changes in mammary-gland acetyl-coenzyme A carboxylase associated with lactogenic differentiation. Biochem J (1977) 1.23
Rapid, reversible internalization of cell surface insulin receptors. Correlation with insulin-induced down-regulation. J Biol Chem (1983) 1.23
Insulin stimulates fluid-phase endocytosis and exocytosis in 3T3-L1 adipocytes. J Biol Chem (1986) 1.22
Tumor necrosis factor alpha promotes nuclear localization of cytokine-inducible CCAAT/enhancer binding protein isoforms in hepatocytes. J Biol Chem (1996) 1.22
Liver acetyl coa carboxylase: the dissociation-reassociation process and its relation to catalytic activity. Proc Natl Acad Sci U S A (1966) 1.21
CCAAT/enhancer binding protein alpha (C/EBP alpha) undifferentiated protein: a developmentally regulated nuclear protein that binds to the C/EBP alpha gene promoter. Proc Natl Acad Sci U S A (1993) 1.21
Insulin-induced down-regulation of insulin receptors in 3T3-L1 adipocytes. Altered rate of receptor inactivation. J Biol Chem (1982) 1.21
Liver acetyl coenzyme A carboxylase. II. Further molecular characterization. J Biol Chem (1968) 1.21
Homogeneous functional insulin receptor from 3T3-L1 adipocytes. Purification using N alpha B1-(biotinyl-epsilon-aminocaproyl)insulin and avidin-sepharose. J Biol Chem (1985) 1.20
Transcriptional control of the stearoyl-CoA desaturase-1 gene by polyunsaturated fatty acids. Biochem Biophys Res Commun (1994) 1.18
Trans-acting factors involved in adipogenic differentiation. Curr Opin Genet Dev (1993) 1.18
Immunological characterization of recombinant antigens isolated from a Mycobacterium avium lambda gt11 expression library by using monoclonal antibody probes. Infect Immun (1991) 1.17
Kinetics of activation of acetyl-CoA carboxylase by citrate. Relationship to the rate of polymerization of the enzyme. J Biol Chem (1983) 1.17
Insulin-dependent phosphorylation of the insulin receptor-protein kinase and activation of glucose transport in 3T3-L1 adipocytes. J Biol Chem (1986) 1.16
Synthesis of epidermal growth factor receptor in human A431 cells. Glycosylation-dependent acquisition of ligand binding activity occurs post-translationally in the endoplasmic reticulum. J Biol Chem (1986) 1.16
Repression of transcription mediated by dual elements in the CCAAT/enhancer binding protein alpha gene. Proc Natl Acad Sci U S A (1997) 1.16
Differentiation of 3T3-L1 fibroblasts to adipocytes. Effect of insulin and indomethacin on the levels of insulin receptors. J Biol Chem (1978) 1.14
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Molecular and catalytic properties of cytosolic acetoacetyl coenzyme A thiolase from avian liver. J Biol Chem (1973) 1.11