Published in Br J Gen Pract on February 01, 1999
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'A coal face option': GPs' perspectives on the rise in antidepressant prescribing. Br J Gen Pract (2009) 1.50
The validity of the diagnosis of depression in general practice: is using criteria for diagnosis as a routine the answer? Br J Gen Pract (2000) 1.03
Impact of a national campaign on GP education: an evaluation of the Defeat Depression Campaign. Br J Gen Pract (1999) 1.83
'You're depressed'; 'no I'm not': GPs' and patients' different models of depression. UMDS MSc in General Practice Teaching Group. Br J Gen Pract (1999) 1.28
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Multi-system neurological disease is common in patients with OPA1 mutations. Brain (2010) 5.37
Mutation of a nuclear receptor gene, NR2E3, causes enhanced S cone syndrome, a disorder of retinal cell fate. Nat Genet (2000) 4.81
A study of the presentation of somatic symptoms in general practice by patients with psychiatric disturbance. Br J Gen Pract (1990) 3.27
Hidden psychiatric illness: use of the general health questionnaire in general practice. J R Coll Gen Pract (1987) 2.93
Mutational hot spot within a new RPGR exon in X-linked retinitis pigmentosa. Nat Genet (2000) 2.82
Identification of the gene that, when mutated, causes the human obesity syndrome BBS4. Nat Genet (2001) 2.77
Close genetic linkage between X-linked retinitis pigmentosa and a restriction fragment length polymorphism identified by recombinant DNA probe L1.28. Nature (1984) 2.52
General practitioners and psychiatry: an opportunity for cooperation and research. Br J Gen Pract (1991) 2.51
GP 2000: a general practitioner for the new millennium. Br J Gen Pract (1996) 2.15
Pitfalls in homozygosity mapping. Am J Hum Genet (2000) 2.12
Unrecognized psychiatric illness in general practice. Br J Gen Pract (1996) 1.95
Should general practitioners be testing for depression? Br J Gen Pract (1994) 1.88
Linkage mapping in 29 Bardet-Biedl syndrome families confirms loci in chromosomal regions 11q13, 15q22.3-q23, and 16q21. Genomics (1997) 1.70
Estimating human inbreeding coefficients: comparison of genealogical and marker heterozygosity approaches. Ann Hum Genet (2006) 1.68
A locus for bipolar affective disorder on chromosome 4p. Nat Genet (1996) 1.67
The brain-derived neurotrophic factor Val66Met polymorphism is associated with age-related change in reasoning skills. Mol Psychiatry (2006) 1.46
Identification of a novel protein interacting with RPGR. Hum Mol Genet (2000) 1.44
Automation of genetic linkage analysis using fluorescent microsatellite markers. Genomics (1994) 1.43
Intrafamilial variation of the phenotype in Bardet-Biedl syndrome. Br J Ophthalmol (1997) 1.43
Moving forward on research. Br J Gen Pract (1991) 1.36
RPGR ORF15 isoform co-localizes with RPGRIP1 at centrioles and basal bodies and interacts with nucleophosmin. Hum Mol Genet (2005) 1.33
Remapping of the RP15 locus for X-linked cone-rod degeneration to Xp11.4-p21.1, and identification of a de novo insertion in the RPGR exon ORF15. Am J Hum Genet (2000) 1.28
A study of genetic linkage heterogeneity in adult polycystic kidney disease. Hum Genet (1987) 1.27
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Evidence for linkage disequilibrium between D16S94 and the adult onset polycystic kidney disease (PKD1) gene. J Med Genet (1992) 1.26
Linkage to D3S47 (C17) in one large autosomal dominant retinitis pigmentosa family and exclusion in another: confirmation of genetic heterogeneity. Am J Hum Genet (1990) 1.20
A family with RP3 type of X-linked retinitis pigmentosa: an association with ciliary abnormalities. Hum Genet (1992) 1.12
Linkage disequilibrium in the region of the autosomal dominant polycystic kidney disease gene (PKD1). Am J Hum Genet (1994) 1.11
Extent of linkage disequilibrium in a Sardinian sub-isolate: sampling and methodological considerations. Hum Mol Genet (2003) 1.08
Phenotypic marker for early disease detection in dominant late-onset retinal degeneration. Invest Ophthalmol Vis Sci (2001) 1.07
A homozygous deletion in RPE65 in a small Sardinian family with autosomal recessive retinal dystrophy. Mol Vis (2000) 1.05
No evidence for linkage between late onset autosomal dominant retinitis pigmentosa and chromosome 3 locus D3S47 (C17): evidence for genetic heterogeneity. Genomics (1990) 1.02
Using human induced pluripotent stem cells to treat retinal disease. Prog Retin Eye Res (2013) 1.00
Living up to expectations? Br J Gen Pract (1995) 1.00
Psychological distress: outcome and consultation rates in one general practice. J R Coll Gen Pract (1988) 1.00
DNA probes in X-linked retinitis pigmentosa. Trans Ophthalmol Soc U K (1983) 0.98
Surgical sterilisation in a New Town practice. Health Bull (Edinb) (1978) 0.98
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Genetic linkage between X-linked retinitis pigmentosa and DNA probe DXS7 (L1.28): further linkage data, heterogeneity testing, and risk estimation. Hum Genet (1986) 0.97
PCR detection of existing and new polymorphism at the TIMP locus. Nucleic Acids Res (1991) 0.96
ZD2767, an improved system for antibody-directed enzyme prodrug therapy that results in tumor regressions in colorectal tumor xenografts. Cancer Res (1996) 0.93
How women felt about their sterilization--a follow-up of 368 patients in a general practice. J R Coll Gen Pract (1981) 0.93
A searchlight through the fog. Nat Genet (1997) 0.92
Renal, cardiovascular and hormonal characteristics of young adults with autosomal dominant polycystic kidney disease. Kidney Int (1991) 0.92
A difficult case. Does it help to know your patient? Br Med J (Clin Res Ed) (1983) 0.89
Modular continuing medical education: our flexible friend? Br J Gen Pract (1994) 0.89
Studies of genetic linkage between adult polycystic kidney disease and three markers on chromosome 16. J Med Genet (1987) 0.89
Short cut to disease genes. Nature (2001) 0.88
Three novel mutations of the RPGR gene exon ORF15 in three Japanese families with X-linked retinitis pigmentosa. Am J Med Genet (2001) 0.88
Continuing to defeat depression. Br J Gen Pract (1995) 0.87
Identification of a 5' splice site mutation in the RPGR gene in a family with X-linked retinitis pigmentosa (RP3). Hum Mutat (1999) 0.87
Fried syndrome is a distinct X linked mental retardation syndrome mapping to Xp22. J Med Genet (1997) 0.86
In vitro and in vivo antitumor activity of ZENECA ZD0490, a recombinant ricin A-chain immunotoxin for the treatment of colorectal cancer. Cancer Res (1994) 0.86
A study of genetic linkage heterogeneity in adult polycystic kidney disease. Trans Assoc Am Physicians (1986) 0.86
DXS26 (HU16) is located in Xq21.1. Hum Genet (1990) 0.86
A simple method for rapid isolation of microsatellites from yeast artificial chromosomes. Mol Cell Probes (1995) 0.86
Effects of angiotensin converting enzyme inhibition in adult polycystic kidney disease. Kidney Int (1992) 0.85
A recombination outside the BB deletion refines the location of the X linked retinitis pigmentosa locus RP3. Am J Hum Genet (1996) 0.85
A genetic linkage study of choroideremia. Ophthalmic Paediatr Genet (1986) 0.82
A genetic linkage study of a kindred with X-linked retinitis pigmentosa. Br J Ophthalmol (1985) 0.81
Analysis of three deletion breakpoints in Xp21.1 and the further localization of RP3. Genomics (1996) 0.81
Antitumor effects of an antibody-carboxypeptidase G2 conjugate in combination with a benzoic acid mustard prodrug. Cell Biophys (1995) 0.80
Follow-up of 375 sterilised women--the view from a general practice. Health Bull (Edinb) (1980) 0.80
Maternal histidine metabolism and its effect on foetal development in the mouse. Nature (1977) 0.80
Sterilisation of women: prevalence and outcome. Br Med J (Clin Res Ed) (1983) 0.79
Multipoint mapping of adult onset polycystic kidney disease (PKD1) on chromosome 16. J Med Genet (1992) 0.79
Education and attitudes in families with adult polycystic kidney disease. Nephrol Dial Transplant (1991) 0.79
Genetics, ageing and dementia. Br J Psychiatry (1984) 0.78
SNP mistyping in genotyping arrays--an important cause of spurious association in case-control studies. Genet Epidemiol (2011) 0.78
Genetic factors in puerperal affective psychoses. Acta Psychiatr Scand (1982) 0.78
Beta-adrenoceptor binding defects in cell lines from families with manic-depressive disorder. Ann Hum Genet (1984) 0.78
Cancer risk in patients with constitutional chromosome deletions: a nationwide British cohort study. Br J Cancer (2008) 0.78
DNA analysis in human disease. J Clin Pathol (1986) 0.78
Adaptive evolution of G-protein coupled receptor genes. Mol Biol Evol (1989) 0.78
Retinitis pigmentosa families showing apparent X linked inheritance but unlinked to the RP2 or RP3 loci. J Med Genet (1994) 0.78
The effect of mutation on linkage disequilibrium. Ann Hum Genet (1992) 0.77
Recombinant single-chain and disulfide-stabilized Fv-immunotoxins that cause complete regression of a human colon cancer xenograft in nude mice. Int J Cancer (1996) 0.77
Recombination patterns around the breakpoints of a balanced 1;11 autosomal translocation associated with major mental illness. Psychiatr Genet (1996) 0.77
Ocular findings in the Laurence-Moon-Bardet-Biedl syndrome. Acta Ophthalmol Scand (1996) 0.77
Cation transport in lymphoblastoid cell lines established from bipolar manic-depressive patients. J Affect Disord (1989) 0.76
Clinical and genetic analysis of a large North European Caucasian family affected by early-onset periodontitis. J Dent Res (2000) 0.76
Contraception by female sterilisation. Br Med J (1980) 0.75
X-linked congenital stationary night blindness: review and report of a family with hyperopia. Arch Ophthalmol (1991) 0.75
A time for change and a time for vision. Br J Gen Pract (1999) 0.75
Familial Alzheimer's disease. Beta amyloid resurrected. Nature (1991) 0.75
Use of the general health questionnaire in clinical work. Br Med J (Clin Res Ed) (1986) 0.75
Linkage analysis in a family with complete type congenital stationary night blindness with and without myopia. Clin Genet (1993) 0.75
People with long-term mental illness: making shared care work. Br J Gen Pract (1995) 0.75
Frequency of rhodopsin codon 23 mutation and retinitis pigmentosa. Lancet (1991) 0.75
Pharmacokinetic studies in mice with ICI D0490, a novel recombinant ricin A-chain immunotoxin. Br J Cancer (1993) 0.75
Haplotype analysis in autosomal dominant polycystic kidney disease. J Med Genet (1995) 0.75
All our tomorrows. Br J Gen Pract (1998) 0.75
Risk calculation in retinitis pigmentosa. Am J Hum Genet (1991) 0.75
Linkage of internal minisatellite loci on chromosome 1 and exclusion of autosomal dominant retinitis pigmentosa proximal to rhesus. J Med Genet (1990) 0.75
A blueprint for shared psychiatric care in the community. Br J Gen Pract (1993) 0.75
CNTF in the embryo. Nat Genet (1994) 0.75
Adult polycystic kidney disease. BMJ (1990) 0.75
Quantitation of specific myeloid cells in rat bone marrow measured by in vitro 35S-sulphate incorporation. J Appl Toxicol (1984) 0.75
The development of mouse monoclonal antibodies that bind and neutralize paraquat. Dev Biol Stand (1987) 0.75
Specific polyclonal and monoclonal antibody prevents paraquat accumulation into rat lung slices. Biochem Pharmacol (1987) 0.75