Published in J R Coll Gen Pract on December 01, 1988
Detecting psychological distress: can general practitioners improve their own performance? Br J Gen Pract (1996) 1.96
Should general practitioners be testing for depression? Br J Gen Pract (1994) 1.88
Sex and attitude: a randomized vignette study of the management of depression by general practitioners. Br J Gen Pract (1999) 1.13
General practitioners' choices and their determinants when starting treatment for major depression: a cross sectional, randomized case-vignette survey. PLoS One (2012) 0.98
Assessment of psychological care in general practice. BMJ (1992) 0.87
Can GPs audit their ability to detect psychological distress? One approach and some unresolved issues. Br J Gen Pract (1998) 0.75
Psychiatric illness in general practice. A detailed study using a new method of case identification. Br Med J (1970) 13.12
Diagnosis--the Achilles heel? J R Coll Gen Pract (1972) 6.63
Determinants of the ability of general practitioners to detect psychiatric illness. Psychol Med (1979) 6.28
Psychiatric screening in general practice. A controlled trial. Lancet (1976) 5.29
Screening for psychiatric disorder in general practice. Psychol Med (1984) 3.18
Hidden psychiatric illness: use of the general health questionnaire in general practice. J R Coll Gen Pract (1987) 2.93
Use of the general health questionnaire in clinical work. Br Med J (Clin Res Ed) (1986) 2.68
Identifying psychiatric illness among general medical patients. Br Med J (Clin Res Ed) (1985) 2.63
Screening for psychiatric illness in general practice: the general practitioner versus the screening questionnaire. J R Coll Gen Pract (1987) 2.60
Ability of primary care physicians to make accurate ratings of psychiatric symptoms. Arch Gen Psychiatry (1982) 1.41
Validity and uses of a screening questionnaire (GHQ) in the community. Br J Psychiatry (1979) 1.15
Emotional disturbance in newly registered general practice patients. Br J Psychiatry (1978) 1.12
Depression in primary care: changes in pattern of patient visits and complaints during a developing depression. J Fam Pract (1978) 1.08
Severity of symptoms of psychiatric outpatients: use of the General Health Questionnaire in hospital ang general practice patients. Psychol Med (1975) 1.07
Psychiatric diagnosis in family practice: is the general health questionnaire an effective screening instrument? South Med J (1980) 0.97
Why don't we use questionnaires in the medical out-patient clinic? Health Bull (Edinb) (1986) 0.81
Multi-system neurological disease is common in patients with OPA1 mutations. Brain (2010) 5.37
Mutation of a nuclear receptor gene, NR2E3, causes enhanced S cone syndrome, a disorder of retinal cell fate. Nat Genet (2000) 4.81
A study of the presentation of somatic symptoms in general practice by patients with psychiatric disturbance. Br J Gen Pract (1990) 3.27
Hidden psychiatric illness: use of the general health questionnaire in general practice. J R Coll Gen Pract (1987) 2.93
Mutational hot spot within a new RPGR exon in X-linked retinitis pigmentosa. Nat Genet (2000) 2.82
Identification of the gene that, when mutated, causes the human obesity syndrome BBS4. Nat Genet (2001) 2.77
Close genetic linkage between X-linked retinitis pigmentosa and a restriction fragment length polymorphism identified by recombinant DNA probe L1.28. Nature (1984) 2.52
General practitioners and psychiatry: an opportunity for cooperation and research. Br J Gen Pract (1991) 2.51
GP 2000: a general practitioner for the new millennium. Br J Gen Pract (1996) 2.15
Pitfalls in homozygosity mapping. Am J Hum Genet (2000) 2.12
Unrecognized psychiatric illness in general practice. Br J Gen Pract (1996) 1.95
Should general practitioners be testing for depression? Br J Gen Pract (1994) 1.88
Linkage mapping in 29 Bardet-Biedl syndrome families confirms loci in chromosomal regions 11q13, 15q22.3-q23, and 16q21. Genomics (1997) 1.70
Estimating human inbreeding coefficients: comparison of genealogical and marker heterozygosity approaches. Ann Hum Genet (2006) 1.68
A locus for bipolar affective disorder on chromosome 4p. Nat Genet (1996) 1.67
The brain-derived neurotrophic factor Val66Met polymorphism is associated with age-related change in reasoning skills. Mol Psychiatry (2006) 1.46
Identification of a novel protein interacting with RPGR. Hum Mol Genet (2000) 1.44
Automation of genetic linkage analysis using fluorescent microsatellite markers. Genomics (1994) 1.43
Intrafamilial variation of the phenotype in Bardet-Biedl syndrome. Br J Ophthalmol (1997) 1.43
Moving forward on research. Br J Gen Pract (1991) 1.36
RPGR ORF15 isoform co-localizes with RPGRIP1 at centrioles and basal bodies and interacts with nucleophosmin. Hum Mol Genet (2005) 1.33
Remapping of the RP15 locus for X-linked cone-rod degeneration to Xp11.4-p21.1, and identification of a de novo insertion in the RPGR exon ORF15. Am J Hum Genet (2000) 1.28
A study of genetic linkage heterogeneity in adult polycystic kidney disease. Hum Genet (1987) 1.27
Primary medical care in France. J R Coll Gen Pract (1975) 1.27
Evidence for linkage disequilibrium between D16S94 and the adult onset polycystic kidney disease (PKD1) gene. J Med Genet (1992) 1.26
Linkage to D3S47 (C17) in one large autosomal dominant retinitis pigmentosa family and exclusion in another: confirmation of genetic heterogeneity. Am J Hum Genet (1990) 1.20
A family with RP3 type of X-linked retinitis pigmentosa: an association with ciliary abnormalities. Hum Genet (1992) 1.12
Linkage disequilibrium in the region of the autosomal dominant polycystic kidney disease gene (PKD1). Am J Hum Genet (1994) 1.11
Extent of linkage disequilibrium in a Sardinian sub-isolate: sampling and methodological considerations. Hum Mol Genet (2003) 1.08
Phenotypic marker for early disease detection in dominant late-onset retinal degeneration. Invest Ophthalmol Vis Sci (2001) 1.07
A homozygous deletion in RPE65 in a small Sardinian family with autosomal recessive retinal dystrophy. Mol Vis (2000) 1.05
No evidence for linkage between late onset autosomal dominant retinitis pigmentosa and chromosome 3 locus D3S47 (C17): evidence for genetic heterogeneity. Genomics (1990) 1.02
Using human induced pluripotent stem cells to treat retinal disease. Prog Retin Eye Res (2013) 1.00
Living up to expectations? Br J Gen Pract (1995) 1.00
Through a glass darkly: understanding depression. Br J Gen Pract (1999) 0.98
DNA probes in X-linked retinitis pigmentosa. Trans Ophthalmol Soc U K (1983) 0.98
Surgical sterilisation in a New Town practice. Health Bull (Edinb) (1978) 0.98
Pulmonary arterial hypertension: basis of sex differences in incidence and treatment response. Br J Pharmacol (2014) 0.97
Genetic linkage between X-linked retinitis pigmentosa and DNA probe DXS7 (L1.28): further linkage data, heterogeneity testing, and risk estimation. Hum Genet (1986) 0.97
PCR detection of existing and new polymorphism at the TIMP locus. Nucleic Acids Res (1991) 0.96
ZD2767, an improved system for antibody-directed enzyme prodrug therapy that results in tumor regressions in colorectal tumor xenografts. Cancer Res (1996) 0.93
How women felt about their sterilization--a follow-up of 368 patients in a general practice. J R Coll Gen Pract (1981) 0.93
Renal, cardiovascular and hormonal characteristics of young adults with autosomal dominant polycystic kidney disease. Kidney Int (1991) 0.92
A searchlight through the fog. Nat Genet (1997) 0.92
A difficult case. Does it help to know your patient? Br Med J (Clin Res Ed) (1983) 0.89
Modular continuing medical education: our flexible friend? Br J Gen Pract (1994) 0.89
Studies of genetic linkage between adult polycystic kidney disease and three markers on chromosome 16. J Med Genet (1987) 0.89
Three novel mutations of the RPGR gene exon ORF15 in three Japanese families with X-linked retinitis pigmentosa. Am J Med Genet (2001) 0.88
Short cut to disease genes. Nature (2001) 0.88
Continuing to defeat depression. Br J Gen Pract (1995) 0.87
Identification of a 5' splice site mutation in the RPGR gene in a family with X-linked retinitis pigmentosa (RP3). Hum Mutat (1999) 0.87
A simple method for rapid isolation of microsatellites from yeast artificial chromosomes. Mol Cell Probes (1995) 0.86
Fried syndrome is a distinct X linked mental retardation syndrome mapping to Xp22. J Med Genet (1997) 0.86
A study of genetic linkage heterogeneity in adult polycystic kidney disease. Trans Assoc Am Physicians (1986) 0.86
DXS26 (HU16) is located in Xq21.1. Hum Genet (1990) 0.86
In vitro and in vivo antitumor activity of ZENECA ZD0490, a recombinant ricin A-chain immunotoxin for the treatment of colorectal cancer. Cancer Res (1994) 0.86
A recombination outside the BB deletion refines the location of the X linked retinitis pigmentosa locus RP3. Am J Hum Genet (1996) 0.85
Effects of angiotensin converting enzyme inhibition in adult polycystic kidney disease. Kidney Int (1992) 0.85
A genetic linkage study of choroideremia. Ophthalmic Paediatr Genet (1986) 0.82
A genetic linkage study of a kindred with X-linked retinitis pigmentosa. Br J Ophthalmol (1985) 0.81
Analysis of three deletion breakpoints in Xp21.1 and the further localization of RP3. Genomics (1996) 0.81
Follow-up of 375 sterilised women--the view from a general practice. Health Bull (Edinb) (1980) 0.80
Antitumor effects of an antibody-carboxypeptidase G2 conjugate in combination with a benzoic acid mustard prodrug. Cell Biophys (1995) 0.80
Maternal histidine metabolism and its effect on foetal development in the mouse. Nature (1977) 0.80
Education and attitudes in families with adult polycystic kidney disease. Nephrol Dial Transplant (1991) 0.79
Multipoint mapping of adult onset polycystic kidney disease (PKD1) on chromosome 16. J Med Genet (1992) 0.79
Sterilisation of women: prevalence and outcome. Br Med J (Clin Res Ed) (1983) 0.79
Genetic factors in puerperal affective psychoses. Acta Psychiatr Scand (1982) 0.78
Adaptive evolution of G-protein coupled receptor genes. Mol Biol Evol (1989) 0.78
Retinitis pigmentosa families showing apparent X linked inheritance but unlinked to the RP2 or RP3 loci. J Med Genet (1994) 0.78
Beta-adrenoceptor binding defects in cell lines from families with manic-depressive disorder. Ann Hum Genet (1984) 0.78
Cancer risk in patients with constitutional chromosome deletions: a nationwide British cohort study. Br J Cancer (2008) 0.78
DNA analysis in human disease. J Clin Pathol (1986) 0.78
Genetics, ageing and dementia. Br J Psychiatry (1984) 0.78
SNP mistyping in genotyping arrays--an important cause of spurious association in case-control studies. Genet Epidemiol (2011) 0.78
Recombinant single-chain and disulfide-stabilized Fv-immunotoxins that cause complete regression of a human colon cancer xenograft in nude mice. Int J Cancer (1996) 0.77
Ocular findings in the Laurence-Moon-Bardet-Biedl syndrome. Acta Ophthalmol Scand (1996) 0.77
The effect of mutation on linkage disequilibrium. Ann Hum Genet (1992) 0.77
Recombination patterns around the breakpoints of a balanced 1;11 autosomal translocation associated with major mental illness. Psychiatr Genet (1996) 0.77
Clinical and genetic analysis of a large North European Caucasian family affected by early-onset periodontitis. J Dent Res (2000) 0.76
Cation transport in lymphoblastoid cell lines established from bipolar manic-depressive patients. J Affect Disord (1989) 0.76
All our tomorrows. Br J Gen Pract (1998) 0.75
People with long-term mental illness: making shared care work. Br J Gen Pract (1995) 0.75
Adult polycystic kidney disease. BMJ (1990) 0.75
Familial Alzheimer's disease. Beta amyloid resurrected. Nature (1991) 0.75
X-linked congenital stationary night blindness: review and report of a family with hyperopia. Arch Ophthalmol (1991) 0.75
Pharmacokinetic studies in mice with ICI D0490, a novel recombinant ricin A-chain immunotoxin. Br J Cancer (1993) 0.75
A time for change and a time for vision. Br J Gen Pract (1999) 0.75
A blueprint for shared psychiatric care in the community. Br J Gen Pract (1993) 0.75
CNTF in the embryo. Nat Genet (1994) 0.75
Linkage of internal minisatellite loci on chromosome 1 and exclusion of autosomal dominant retinitis pigmentosa proximal to rhesus. J Med Genet (1990) 0.75
Risk calculation in retinitis pigmentosa. Am J Hum Genet (1991) 0.75
Haplotype analysis in autosomal dominant polycystic kidney disease. J Med Genet (1995) 0.75
Linkage analysis in a family with complete type congenital stationary night blindness with and without myopia. Clin Genet (1993) 0.75
Frequency of rhodopsin codon 23 mutation and retinitis pigmentosa. Lancet (1991) 0.75
Contraception by female sterilisation. Br Med J (1980) 0.75
Use of the general health questionnaire in clinical work. Br Med J (Clin Res Ed) (1986) 0.75
Manic depressive psychosis with mental retardation and flexion deformities: a clinical and cytogenetic study. Br J Psychiatry (1987) 0.75
Linkage analysis in manic-depressive illness. Lancet (1987) 0.75
The diagnosis of autosomal dominant late-onset retinal degeneration in two sisters. Eye (Lond) (2003) 0.75