Published in Mol Cell Biol on June 01, 1999
Site-specific androgen receptor serine phosphorylation linked to epidermal growth factor-dependent growth of castration-recurrent prostate cancer. J Biol Chem (2008) 1.32
Subnuclear localization of Ku protein: functional association with RNA polymerase II elongation sites. Mol Cell Biol (2002) 1.23
DNA-PK contributes to the phosphorylation of AIRE: importance in transcriptional activity. Biochim Biophys Acta (2007) 1.10
The Ku protein complex interacts with YY1, is up-regulated in human heart failure, and represses alpha myosin heavy-chain gene expression. Mol Cell Biol (2004) 1.02
Activation and autoregulation of DNA-PK from structured single-stranded DNA and coding end hairpins. Proc Natl Acad Sci U S A (2001) 0.86
Identification of proteins binding to E-Box/Ku86 sites and function of the tumor suppressor SAFB1 in transcriptional regulation of the human xanthine oxidoreductase gene. J Biol Chem (2008) 0.82
Impact of the Ku complex on HIV-1 expression and latency. PLoS One (2013) 0.81
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Computational studies on full-length Ku70 with DNA duplexes: base interactions and a helical path. J Mol Model (2011) 0.75
Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res (1983) 124.30
Gene regulation by steroid hormones. Cell (1989) 12.96
The DNA-dependent protein kinase: requirement for DNA ends and association with Ku antigen. Cell (1993) 7.17
Requirement for Ku80 in growth and immunoglobulin V(D)J recombination. Nature (1996) 5.80
Components of the Ku-dependent non-homologous end-joining pathway are involved in telomeric length maintenance and telomeric silencing. EMBO J (1998) 5.79
Defective DNA-dependent protein kinase activity is linked to V(D)J recombination and DNA repair defects associated with the murine scid mutation. Cell (1995) 5.58
Ku80: product of the XRCC5 gene and its role in DNA repair and V(D)J recombination. Science (1994) 4.99
Silencing factors participate in DNA repair and recombination in Saccharomyces cerevisiae. Nature (1997) 4.57
DNA-dependent kinase (p350) as a candidate gene for the murine SCID defect. Science (1995) 4.54
Ku70-deficient embryonic stem cells have increased ionizing radiosensitivity, defective DNA end-binding activity, and inability to support V(D)J recombination. Proc Natl Acad Sci U S A (1997) 4.13
Ku86-deficient mice exhibit severe combined immunodeficiency and defective processing of V(D)J recombination intermediates. Cell (1996) 4.11
The hormone regulatory element of mouse mammary tumour virus mediates progesterone induction. EMBO J (1986) 4.04
Yeast Ku as a regulator of chromosomal DNA end structure. Science (1998) 3.86
Steroid-dependent interaction of transcription factors with the inducible promoter of mouse mammary tumor virus in vivo. Cell (1987) 3.74
Human DNA-activated protein kinase phosphorylates serines 15 and 37 in the amino-terminal transactivation domain of human p53. Mol Cell Biol (1992) 3.68
Restoration of X-ray resistance and V(D)J recombination in mutant cells by Ku cDNA. Science (1994) 3.47
Dexamethasone-mediated induction of mouse mammary tumor virus RNA: a system for studying glucocorticoid action. Cell (1975) 3.44
Transcription factor loading on the MMTV promoter: a bimodal mechanism for promoter activation. Science (1992) 3.13
DNA double-strand break repair and V(D)J recombination: involvement of DNA-PK. Trends Biochem Sci (1995) 3.01
Loss of the catalytic subunit of the DNA-dependent protein kinase in DNA double-strand-break-repair mutant mammalian cells. Proc Natl Acad Sci U S A (1995) 2.99
DNA-dependent protein kinase activity is absent in xrs-6 cells: implications for site-specific recombination and DNA double-strand break repair. Proc Natl Acad Sci U S A (1995) 2.87
Interaction of DNA-dependent protein kinase with DNA and with Ku: biochemical and atomic-force microscopy studies. EMBO J (1997) 2.78
Mineralocorticoid and glucocorticoid receptor activities distinguished by nonreceptor factors at a composite response element. Science (1993) 2.77
Analysis of the mechanism of interaction of simian Ku protein with DNA. Nucleic Acids Res (1991) 2.76
HeLa nuclear protein recognizing DNA termini and translocating on DNA forming a regular DNA-multimeric protein complex. J Mol Biol (1989) 2.73
Ku70 is required for DNA repair but not for T cell antigen receptor gene recombination In vivo. J Exp Med (1997) 2.71
Early events in the stimulation of mammary tumor virus RNA synthesis by glucocorticoids. Novel assays of transcription rates. J Biol Chem (1984) 2.68
Binding of Ku protein to DNA. Measurement of affinity for ends and demonstration of binding to nicks. J Biol Chem (1993) 2.66
Functional interactions between Stat5 and the glucocorticoid receptor. Nature (1996) 2.64
Functional dissection of the hormone and DNA binding activities of the glucocorticoid receptor. EMBO J (1987) 2.46
EBP-80, a transcription factor closely resembling the human autoantigen Ku, recognizes single- to double-strand transitions in DNA. J Biol Chem (1993) 2.34
DNA-dependent protein kinase: DNA binding and activation in the absence of Ku. Proc Natl Acad Sci U S A (1998) 2.30
Ku70: a candidate tumor suppressor gene for murine T cell lymphoma. Mol Cell (1998) 2.18
Hypersensitivity of Ku80-deficient cell lines and mice to DNA damage: the effects of ionizing radiation on growth, survival, and development. Proc Natl Acad Sci U S A (1997) 2.12
Hormone induces binding of receptors and transcription factors to a rearranged nucleosome on the MMTV promoter in vivo. EMBO J (1995) 2.09
Purification and characterization of a template-associated protein kinase that phosphorylates RNA polymerase II. J Biol Chem (1993) 2.08
The nuclear serine/threonine protein kinase DNA-PK. Crit Rev Eukaryot Gene Expr (1992) 2.05
DNA-dependent protein kinase (Ku protein-p350 complex) assembles on double-stranded DNA. Proc Natl Acad Sci U S A (1994) 2.01
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Human DNA helicase II: a novel DNA unwinding enzyme identified as the Ku autoantigen. EMBO J (1994) 1.84
The DNA-activated protein kinase is required for the phosphorylation of replication protein A during simian virus 40 DNA replication. Proc Natl Acad Sci U S A (1994) 1.79
Ku polypeptides synthesized in vitro assemble into complexes which recognize ends of double-stranded DNA. J Biol Chem (1992) 1.75
Sequence-specific DNA binding by Ku autoantigen and its effects on transcription. Nature (1996) 1.75
Mammalian mutants defective in the response to ionizing radiation-induced DNA damage. Mutat Res (1995) 1.59
Productive and nonproductive complexes of Ku and DNA-dependent protein kinase at DNA termini. Mol Cell Biol (1998) 1.51
Repression of GCN5 histone acetyltransferase activity via bromodomain-mediated binding and phosphorylation by the Ku-DNA-dependent protein kinase complex. Mol Cell Biol (1998) 1.50
Mouse mammary tumor virus proviruses in T-cell lymphomas lack a negative regulatory element in the long terminal repeat. J Virol (1988) 1.42
DNA-PK: at the cross-roads of biochemistry and genetics. Mutat Res (1997) 1.40
Protein-protein and protein-DNA interaction regions within the DNA end-binding protein Ku70-Ku86. Mol Cell Biol (1996) 1.39
DNA-dependent protein kinase: a potent inhibitor of transcription by RNA polymerase I. Genes Dev (1995) 1.34
Alterations in the U3 region of the long terminal repeat of an infectious thymotropic type B retrovirus. J Virol (1988) 1.33
Production and characterization of recombinant human Ku antigen. Nucleic Acids Res (1994) 1.32
Transcriptional repression of a hormone-responsive promoter. Nucleic Acids Res (1987) 1.30
Nuclear factor I acts as a transcription factor on the MMTV promoter but competes with steroid hormone receptors for DNA binding. EMBO J (1990) 1.29
Double-strand break repair by Ku70 requires heterodimerization with Ku80 and DNA binding functions. EMBO J (1997) 1.28
Chromatin structure and the regulation of gene expression: remodeling at the MMTV promoter. J Mol Med (Berl) (1996) 1.15
Sequence-specific DNA binding and transcription factor phosphorylation by Ku Autoantigen/DNA-dependent protein kinase. Phosphorylation of Ser-527 of the rat glucocorticoid receptor. J Biol Chem (1997) 1.11
The interaction between Ku antigen and REF1 protein mediates negative gene regulation by extracellular calcium. J Biol Chem (1996) 1.10
The long terminal repeat region of the mouse mammary tumour virus contains multiple regulatory elements. Nucleic Acids Res (1990) 1.08
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DNA-dependent protein kinase specifically represses promoter-directed transcription initiation by RNA polymerase I. Proc Natl Acad Sci U S A (1995) 1.03
Oncogene activation and oncogene cooperation in MMTV-induced mouse mammary cancer. Semin Cancer Biol (1995) 1.02
Mechanism of DNA-dependent protein kinase inhibition by cis-diamminedichloroplatinum(II)-damaged DNA. Biochemistry (1997) 1.01
Purification of the sequence-specific transcription factor CTCBF, involved in the control of human collagen IV genes: subunits with homology to Ku antigen. EMBO J (1995) 1.01
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Regulation and repair of double-strand DNA breaks. Crit Rev Eukaryot Gene Expr (1996) 0.96
p95vav associates with the nuclear protein Ku-70. Mol Cell Biol (1996) 0.96
The 86-kDa subunit of autoantigen Ku is a somatostatin receptor regulating protein phosphatase-2A activity. J Biol Chem (1994) 0.95
Mineralocorticoid regulation of transcription of transfected mouse mammary tumor virus DNA in cultured kidney cells. J Cell Biol (1988) 0.94
Sequence-specific binding of Ku autoantigen to single-stranded DNA. J Biol Chem (1998) 0.93
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Functional properties of the separate subunits of human DNA helicase II/Ku autoantigen. J Biol Chem (1997) 0.90
Similar DNA binding properties of free P70 (KU) subunit and P70/P80 heterodimer. FEBS Lett (1994) 0.88
Heat shock transcription factor 1 binds selectively in vitro to Ku protein and the catalytic subunit of the DNA-dependent protein kinase. J Biol Chem (1997) 0.87
Purification and characterization of a cellular protein that binds to the downstream activation sequence of the strict late UL38 promoter of herpes simplex virus type 1. J Virol (1998) 0.87
Identification and characterization of a cis-acting element that interferes with glucocorticoid-inducible activation of the mouse mammary tumor virus promoter. Proc Natl Acad Sci U S A (1991) 0.86
Failure of hairpin-ended and nicked DNA To activate DNA-dependent protein kinase: implications for V(D)J recombination. Mol Cell Biol (1998) 0.85
Prolactin effects on the dietary regulation of mouse mammary tumor virus proviral DNA expression. Proc Natl Acad Sci U S A (1990) 0.85
Diethylpyrocarbonate and permanganate provide evidence for an unusual DNA conformation induced by binding of the antitumour antibiotics bleomycin and phleomycin. Nucleic Acids Res (1988) 0.84
Altered mouse mammary tumor virus transcript synthesis in T-cell lymphoma cells. J Virol (1990) 0.82
Mouse mammary tumor virus and mammary tumorigenesis in wild mice. Pathol Int (1996) 0.81
Repression of mouse mammary tumor virus transcription by a transcription factor complex. Binding of individual components to separated DNA strands. J Biol Chem (1994) 0.81
Hypersensitivity of Ku-deficient cells toward the DNA topoisomerase II inhibitor ICRF-193 suggests a novel role for Ku antigen during the G2 and M phases of the cell cycle. Mol Cell Biol (1998) 0.80
Nuclear factor binding to a DNA sequence element that represses MMTV transcription induces a structural transition and leads to the contact of single-stranded binding proteins with DNA. DNA Cell Biol (1995) 0.77
Human prolactin regulates transfected MMTV LTR-directed gene expression in a human breast-carcinoma cell line through synergistic interaction with steroid hormones. Int J Cancer (1992) 0.77
Multi-strand binding of nuclear factors to a repressor of mouse mammary tumor virus transcription can be distinguished kinetically. Biochem Biophys Res Commun (1995) 0.75
Activation of the Src/p21ras/Erk pathway by progesterone receptor via cross-talk with estrogen receptor. EMBO J (1998) 2.58
A seven-transmembrane, G protein-coupled receptor, FPRL1, mediates the chemotactic activity of serum amyloid A for human phagocytic cells. J Exp Med (1999) 2.32
Hormone induces binding of receptors and transcription factors to a rearranged nucleosome on the MMTV promoter in vivo. EMBO J (1995) 2.09
Human recombinant monocyte chemotactic protein and other C-C chemokines bind and induce directional migration of dendritic cells in vitro. J Leukoc Biol (1996) 2.05
Aberrant FoxM1B expression increases matrix metalloproteinase-2 transcription and enhances the invasion of glioma cells. Oncogene (2007) 1.98
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Cloning a balanced translocation associated with DiGeorge syndrome and identification of a disrupted candidate gene. Nat Genet (1995) 1.68
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Insight into the catalytic mechanism of DNA polymerase beta: structures of intermediate complexes. Biochemistry (2001) 1.62
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Isolation and characterization of a gene from the DiGeorge chromosomal region homologous to the mouse Tbx1 gene. Genomics (1997) 1.33
Utilization of two seven-transmembrane, G protein-coupled receptors, formyl peptide receptor-like 1 and formyl peptide receptor, by the synthetic hexapeptide WKYMVm for human phagocyte activation. J Immunol (1999) 1.29
Blocking swelling-activated chloride current inhibits mouse liver cell proliferation. J Physiol (2001) 1.28
Mutation analysis of TBX1 in non-deleted patients with features of DGS/VCFS or isolated cardiovascular defects. J Med Genet (2001) 1.24
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The 5' noncoding and flanking regions of the avian very low density apolipoprotein II and serum albumin genes. Homologies with the egg white protein genes. J Biol Chem (1983) 1.17
The neurotoxic prion peptide fragment PrP(106-126) is a chemotactic agonist for the G protein-coupled receptor formyl peptide receptor-like 1. J Immunol (2001) 1.13
Disruption of the clathrin heavy chain-like gene (CLTCL) associated with features of DGS/VCFS: a balanced (21;22)(p12;q11) translocation. Hum Mol Genet (1997) 1.12
Sequence-specific DNA binding and transcription factor phosphorylation by Ku Autoantigen/DNA-dependent protein kinase. Phosphorylation of Ser-527 of the rat glucocorticoid receptor. J Biol Chem (1997) 1.11
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Structural basis for the design of antibiotics targeting peptide deformylase. Biochemistry (1999) 1.08
Biological reduction of uranium in groundwater and subsurface soil. Sci Total Environ (2000) 1.07
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The G-protein-coupled formylpeptide receptor FPR confers a more invasive phenotype on human glioblastoma cells. Br J Cancer (2010) 1.04
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A region of mouse chromosome 16 is syntenic to the DiGeorge, velocardiofacial syndrome minimal critical region. Genome Res (1997) 1.03
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Synthetic peptide MMK-1 is a highly specific chemotactic agonist for leukocyte FPRL1. J Leukoc Biol (2001) 0.98
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Desensitization of chemokine receptor CCR5 in dendritic cells at the early stage of differentiation by activation of formyl peptide receptors. Clin Immunol (2001) 0.95
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Purification and identification of chemokines potentially involved in kidney-specific metastasis by a murine lymphoma variant: induction of migration and NFkappaB activation. Int J Cancer (1998) 0.92
The binding of Ku antigen to homeodomain proteins promotes their phosphorylation by DNA-dependent protein kinase. J Biol Chem (2001) 0.92
Evaluating risk loci for schizophrenia distilled from genome-wide association studies in Han Chinese from Central China. Mol Psychiatry (2012) 0.91
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HIV-1 envelope gp120 inhibits the monocyte response to chemokines through CD4 signal-dependent chemokine receptor down-regulation. J Immunol (1998) 0.89
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