Published in Biol Psychiatry on May 01, 1999
22q11.2 microdeletions: linking DNA structural variation to brain dysfunction and schizophrenia. Nat Rev Neurosci (2010) 2.54
Variation in dopamine genes influences responsivity of the human reward system. Proc Natl Acad Sci U S A (2008) 2.13
Orofacial pain prospective evaluation and risk assessment study--the OPPERA study. J Pain (2011) 1.62
Is obsessive-compulsive disorder an autoimmune disease? CMAJ (2001) 1.48
The transmission/disequilibrium test and parental-genotype reconstruction for X-chromosomal markers. Am J Hum Genet (2000) 1.32
The quantification of COMT mRNA in post mortem cerebellum tissue: diagnosis, genotype, methylation and expression. BMC Med Genet (2006) 1.24
A gender-moderated effect of a functional COMT polymorphism on prefrontal brain morphology and function in velo-cardio-facial syndrome (22q11.2 deletion syndrome). Am J Med Genet B Neuropsychiatr Genet (2006) 1.19
Search for genetic markers and functional variants involved in the development of opiate and cocaine addiction and treatment. Ann N Y Acad Sci (2010) 1.16
The OCD collaborative genetics study: methods and sample description. Am J Med Genet B Neuropsychiatr Genet (2006) 1.08
Genetic animal models of anxiety. Neurogenetics (2003) 1.00
Glutamatergic Synaptic Dysfunction and Obsessive-Compulsive Disorder. Curr Chem Genomics (2008) 0.95
The genetics of obsessive-compulsive disorder: a review. Dialogues Clin Neurosci (2010) 0.95
Anxiety and affective disorder comorbidity related to serotonin and other neurotransmitter systems: obsessive-compulsive disorder as an example of overlapping clinical and genetic heterogeneity. Philos Trans R Soc Lond B Biol Sci (2013) 0.94
Comprehensive family-based association study of the glutamate transporter gene SLC1A1 in obsessive-compulsive disorder. Am J Med Genet B Neuropsychiatr Genet (2011) 0.93
Haplotype associations with quantitative traits in the presence of complex multilocus and heterogeneous effects. Genet Epidemiol (2009) 0.91
Genetics of obsessive-compulsive disorder. Psychiatr Clin North Am (2010) 0.90
Genetic and environmental influences on obsessive-compulsive disorder. Eur Arch Psychiatry Clin Neurosci (2008) 0.90
Transmission disequilibrium studies in early onset of obsessive-compulsive disorder for polymorphisms in genes of the dopaminergic system. J Neural Transm (Vienna) (2008) 0.89
Catechol-O-methyltransferase (COMT) gene variants: possible association of the Val158Met variant with opiate addiction in Hispanic women. Am J Med Genet B Neuropsychiatr Genet (2008) 0.86
Emotional symptoms in children: The effect of maternal depression, life events, and COMT genotype. Am J Med Genet B Neuropsychiatr Genet (2009) 0.85
Annual Research Review: Transgenic mouse models of childhood-onset psychiatric disorders. J Child Psychol Psychiatry (2011) 0.84
Pharmacogenetics of anxiolytic drugs. J Neural Transm (Vienna) (2009) 0.83
Gonadectomy and hormone replacement exert region- and enzyme isoform-specific effects on monoamine oxidase and catechol-O-methyltransferase activity in prefrontal cortex and neostriatum of adult male rats. Neuroscience (2009) 0.81
Polymorphisms and disease: hotspots of inactivation in methyltransferases. Trends Biochem Sci (2010) 0.81
Neuroanatomical phenotypes in a mouse model of the 22q11.2 microdeletion. Mol Psychiatry (2013) 0.81
A Framework for Understanding the Emerging Role of Corticolimbic-Ventral Striatal Networks in OCD-Associated Repetitive Behaviors. Front Syst Neurosci (2015) 0.80
Investigating the molecular basis of major depressive disorder etiology: a functional convergent genetic approach. Ann N Y Acad Sci (2008) 0.80
The genetic studies of obsessive-compulsive disorder and its future directions. Yonsei Med J (2006) 0.80
The c.1460C>T polymorphism of MAO-A is associated with the risk of depression in postmenopausal women. ScientificWorldJournal (2012) 0.79
Association analysis of monoamine oxidase A gene and bipolar affective disorder in Han Chinese. Behav Brain Funct (2008) 0.79
An integrated molecular landscape implicates the regulation of dendritic spine formation through insulin-related signalling in obsessive-compulsive disorder. J Psychiatry Neurosci (2016) 0.78
Dopaminergic modulation of memory and affective processing in Parkinson depression. Psychiatry Res (2013) 0.78
The Genetics of Obsessive-Compulsive Disorder. Curr Psychiatry Rev (2010) 0.77
D2 and D3 dopamine receptor affinity predicts effectiveness of antipsychotic drugs in obsessive-compulsive disorders: a metaregression analysis. Psychopharmacology (Berl) (2014) 0.77
Catechol-O-methyltransferase gene val158met polymorphism and depressive symptoms during early childhood. Am J Med Genet B Neuropsychiatr Genet (2013) 0.76
Genetic covariance between psychopathic traits and anticipatory skin conductance responses to threat: Evidence for a potential endophenotype. Dev Psychopathol (2015) 0.76
Both the COMT Val158Met single-nucleotide polymorphism and sex-dependent differences influence response inhibition. Front Behav Neurosci (2015) 0.75
ORCHIDS: an observational randomized controlled trial on childhood differential susceptibility. BMC Public Health (2012) 0.75
Catecholaminergic gene variants: contribution in ADHD and associated comorbid attributes in the eastern Indian probands. Biomed Res Int (2013) 0.75
Multilocus linkage analysis in humans: detection of linkage and estimation of recombination. Am J Hum Genet (1985) 87.59
Strategies for multilocus linkage analysis in humans. Proc Natl Acad Sci U S A (1984) 48.41
Estimation of the recombination fraction in human pedigrees: efficient computation of the likelihood for human linkage studies. Am J Hum Genet (1974) 23.66
The rapid generation of oligonucleotide-directed mutations at high frequency using phosphorothioate-modified DNA. Nucleic Acids Res (1985) 12.11
Trimming, weighting, and grouping SNPs in human case-control association studies. Genome Res (2001) 9.41
A haplotype-based 'haplotype relative risk' approach to detecting allelic associations. Hum Hered (1992) 8.71
A computer program for linkage analysis of general human pedigrees. Am J Hum Genet (1976) 6.01
Report of the Committee on Methods of Linkage Analysis and Reporting. Cytogenet Cell Genet (1985) 5.61
Chromosome-based method for rapid computer simulation in human genetic linkage analysis. Genet Epidemiol (1993) 4.98
Linkage of a prion protein missense variant to Gerstmann-Sträussler syndrome. Nature (1989) 4.69
A worldwide study of the Huntington's disease mutation. The sensitivity and specificity of measuring CAG repeats. N Engl J Med (1994) 4.60
Counting methods (EM algorithm) in human pedigree analysis: linkage and segregation analysis. Ann Hum Genet (1977) 4.54
Relationship estimation in affected sib pair analysis of late-onset diseases. Eur J Hum Genet (1997) 4.16
Linkage analysis and family classification under heterogeneity. Ann Hum Genet (1983) 3.76
Two-trait-locus linkage analysis: a powerful strategy for mapping complex genetic traits. Am J Hum Genet (1993) 3.76
Maximum likelihood estimation by counting methods under polygenic and mixed models in human pedigrees. Am J Hum Genet (1979) 3.36
The p53MH algorithm and its application in detecting p53-responsive genes. Proc Natl Acad Sci U S A (2002) 3.11
A simple scheme for the analysis of HLA linkages in pedigrees. Ann Hum Genet (1978) 3.01
Patterns of Candida endocarditis following cardiac surgery: Importance of early diagnosis and therapy (an analysis of 91 cases). Prog Cardiovasc Dis (1974) 2.95
Report of the committee on linkage and gene order. Cytogenet Cell Genet (1989) 2.76
A transmission/disequilibrium test that allows for genotyping errors in the analysis of single-nucleotide polymorphism data. Am J Hum Genet (2001) 2.68
Linkage studies in a large kindred with familial hypercholesterolemia. Am J Hum Genet (1974) 2.49
Measuring the inflation of the lod score due to its maximization over model parameter values in human linkage analysis. Genet Epidemiol (1990) 2.47
Predisposition to familial osteoarthrosis linked to type II collagen gene. Lancet (1989) 2.43
A microsatellite genetic linkage map of human chromosome 18. Genomics (1993) 2.35
A genomewide screen for autism susceptibility loci. Am J Hum Genet (2001) 2.30
Identification of a novel common genetic risk factor for lumbar disk disease. JAMA (2001) 2.28
Alopecia universalis associated with a mutation in the human hairless gene. Science (1998) 2.23
Age-related macular degeneration. Clinical features in a large family and linkage to chromosome 1q. Arch Ophthalmol (1998) 2.19
A chi-square test to distinguish allelic association from other causes of phenotypic association between two loci. Genet Epidemiol (1985) 2.15
Risk calculations under heterogeneity. Am J Hum Genet (1989) 2.07
Selecting SNPs in two-stage analysis of disease association data: a model-free approach. Ann Hum Genet (2000) 2.05
Genetic susceptibility to heroin addiction: a candidate gene association study. Genes Brain Behav (2008) 2.00
Determinants of weaning and survival among patients with COPD who require mechanical ventilation for acute respiratory failure. Chest (1989) 1.97
Linkage analysis with misclassification at one locus. Clin Genet (1977) 1.89
Optic atrophy in Leber hereditary optic neuroretinopathy is probably determined by an X-chromosomal gene closely linked to DXS7. Am J Hum Genet (1991) 1.89
True pedigree errors more frequent than apparent errors for single nucleotide polymorphisms. Hum Hered (1999) 1.88
Tests of gene order from three-locus linkage data. Ann Hum Genet (1987) 1.87
Colonic stenting as a bridge to surgery in malignant large-bowel obstruction: a report from two large multinational registries. Am J Gastroenterol (2011) 1.86
An allele of COL9A2 associated with intervertebral disc disease. Science (1999) 1.85
Molecular and statistical approaches to the detection and correction of errors in genotype databases. Am J Hum Genet (1993) 1.84
Phaeohyphomycosis caused by Phaeoacremonium inflatipes. J Clin Microbiol (1998) 1.78
GT repeats are associated with recombination on human chromosome 22. Genome Res (2000) 1.75
Scan statistics to scan markers for susceptibility genes. Proc Natl Acad Sci U S A (2000) 1.73
Risk factors for postoperative bleeding after thyroid surgery. Br J Surg (2012) 1.72
Family cell lines available for research. Am J Hum Genet (1990) 1.72
Goodness-of-fit tests for locus order in three-point mapping. Genet Epidemiol (1987) 1.71
Evidence for linkage of Charcot-Marie-Tooth neuropathy to the Duffy locus on chromosome 1. Am J Hum Genet (1982) 1.69
Epidemiology and factor analysis of obesity, type II diabetes, hypertension, and dyslipidemia (syndrome X) on the Island of Kosrae, Federated States of Micronesia. Hum Hered (2001) 1.67
Transverse-momentum and pseudorapidity distributions of charged hadrons in pp collisions at square root of s = 7 TeV. Phys Rev Lett (2010) 1.67
Neural network analysis of complex traits. Genet Epidemiol (1997) 1.63
Assessment and management of single nucleotide polymorphism genotype errors in genetic association analysis. Pac Symp Biocomput (2001) 1.62
Refined assignment of the infantile neuronal ceroid lipofuscinosis (INCL, CLN1) locus at 1p32: incorporation of linkage disequilibrium in multipoint analysis. Genomics (1993) 1.61
TULP1 mutation in two extended Dominican kindreds with autosomal recessive retinitis pigmentosa. Nat Genet (1998) 1.60
Role of inducible nitric oxide synthase in endotoxin-induced acute lung injury. Am J Respir Crit Care Med (1998) 1.60
A microsatellite genetic linkage map of human chromosome 13. Genomics (1993) 1.57
Substantial attributable risk related to a functional mu-opioid receptor gene polymorphism in association with heroin addiction in central Sweden. Mol Psychiatry (2004) 1.56
A genome-wide search for chromosomal loci linked to bipolar affective disorder in the Old Order Amish. Nat Genet (1996) 1.56
Study of the mass and spin-parity of the Higgs boson candidate via its decays to Z boson pairs. Phys Rev Lett (2013) 1.56
Mapping of a gene for severe pediatric gastroesophageal reflux to chromosome 13q14. JAMA (2000) 1.56
Adrenoleukodystrophy: phenotypic variability and implications for therapy. J Inherit Metab Dis (1992) 1.52
Multiple sclerosis: decreased relapse rate through dietary supplementation with calcium, magnesium and vitamin D. Med Hypotheses (1986) 1.52
Multi-locus nonparametric linkage analysis of complex trait loci with neural networks. Hum Hered (1998) 1.49
Expression of monocyte human leukocyte antigen-DR in relation with sepsis severity and plasma mediators. Minerva Anestesiol (2009) 1.48
Report of the committee on linkage and gene order. Cytogenet Cell Genet (1990) 1.48
Sequential cervical length screening in pregnancies after loop excision of the transformation zone conisation: a retrospective analysis. BJOG (2013) 1.47
p63 consensus DNA-binding site: identification, analysis and application into a p63MH algorithm. Oncogene (2007) 1.45
Applications of neural networks for gene finding. Adv Genet (2001) 1.44
Filter disc supported oligonucleotide synthesis by the phosphite method. Nucleic Acids Res (1984) 1.43
Detection of rare major genes in lipid levels. Hum Genet (1979) 1.40
Estimating distances from the centromere by means of benign ovarian teratomas in man. Ann Hum Genet (1976) 1.40
Linkage probability and its approximate confidence interval under possible heterogeneity. Genet Epidemiol Suppl (1986) 1.39
Multipoint linkage analysis and heterogeneity testing in 20 X-linked retinitis pigmentosa families. Genomics (1990) 1.38
The role of MMAC1 mutations in early-onset breast cancer: causative in association with Cowden syndrome and excluded in BRCA1-negative cases. Am J Hum Genet (1997) 1.37
Guidelines for human linkage maps: an international system for human linkage maps (ISLM, 1990). Genomics (1991) 1.37
Linkage analyses of chromosome 18 markers do not identify a major susceptibility locus for bipolar affective disorder in the Old Order Amish. Am J Hum Genet (1995) 1.35
Mutation and polymorphism of the prion protein gene in Libyan Jews with Creutzfeldt-Jakob disease (CJD). Am J Hum Genet (1993) 1.34
Evidence that the penetrance of mutations at the RP11 locus causing dominant retinitis pigmentosa is influenced by a gene linked to the homologous RP11 allele. Am J Hum Genet (1997) 1.34
Heterogeneity analysis of breast cancer families by using age at onset as a covariate. Am J Hum Genet (1992) 1.33
Continuous positive airway pressure reduces work of breathing and dyspnea during weaning from mechanical ventilation in severe chronic obstructive pulmonary disease. Am Rev Respir Dis (1990) 1.32
Heroin addiction in African Americans: a hypothesis-driven association study. Genes Brain Behav (2009) 1.32
First-stage autosomal genome screen in extended pedigrees suggests genes predisposing to low bone mineral density on chromosomes 1p, 2p and 4q. Eur J Hum Genet (1998) 1.32
Significant evidence for linkage disequilibrium over a 5-cM region among Afrikaners. Genomics (2000) 1.31
Polymorphisms in C2, CFB and C3 are associated with progression to advanced age related macular degeneration associated with visual loss. J Med Genet (2008) 1.31
Genetic linkage evidence for heterogeneity in Charcot-Marie-Tooth neuropathy (HMSN type I). Ann Neurol (1983) 1.30
Environmental exposure to tremolite and respiratory cancer in New Caledonia: a case-control study. Am J Epidemiol (2000) 1.29
Multiple zinc finger forms resulting from developmentally regulated alternative splicing of a transcription factor gene. Science (1992) 1.28
Analysis of complex traits using neural networks. Genet Epidemiol (1999) 1.27
ESR dates for the hominid burial site of Es Skhul in Israel. Nature (1989) 1.27
Familial rheumatoid arthritis: linkage of HLA to disease susceptibility locus in four families where proband presented with juvenile rheumatoid arthritis. J Clin Invest (1980) 1.26
Exposing the human nude phenotype. Nature (1999) 1.26
Guidelines for human linkage maps. An International System for Human Linkage Maps (ISLM, 1990). Ann Hum Genet (1991) 1.25
Genotype patterns that contribute to increased risk for or protection from developing heroin addiction. Mol Psychiatry (2008) 1.25
Pseudoxanthoma elasticum maps to an 820-kb region of the p13.1 region of chromosome 16. Genomics (1999) 1.24
Ciliary neurotrophic factor improves diabetic parameters and hepatic steatosis and increases basal metabolic rate in db/db mice. Proc Natl Acad Sci U S A (2003) 1.24
Linkage evidence for genetic heterogeneity among kinships with hereditary motor and sensory neuropathy, type I. Mayo Clin Proc (1983) 1.24
Genotype determining low catechol-O-methyltransferase activity as a risk factor for obsessive-compulsive disorder. Proc Natl Acad Sci U S A (1997) 1.24