Published in Proc Natl Acad Sci U S A on June 19, 2002
The coordinate regulation of the p53 and mTOR pathways in cells. Proc Natl Acad Sci U S A (2005) 7.38
Glutaminase 2, a novel p53 target gene regulating energy metabolism and antioxidant function. Proc Natl Acad Sci U S A (2010) 4.99
p53-Responsive micrornas 192 and 215 are capable of inducing cell cycle arrest. Cancer Res (2008) 3.58
Species-specific endogenous retroviruses shape the transcriptional network of the human tumor suppressor protein p53. Proc Natl Acad Sci U S A (2007) 3.00
Characterization of genome-wide p53-binding sites upon stress response. Nucleic Acids Res (2008) 2.67
p53 isoform delta113p53 is a p53 target gene that antagonizes p53 apoptotic activity via BclxL activation in zebrafish. Genes Dev (2009) 2.57
Distinct p53 genomic binding patterns in normal and cancer-derived human cells. Cell Cycle (2011) 2.01
Parkin, a p53 target gene, mediates the role of p53 in glucose metabolism and the Warburg effect. Proc Natl Acad Sci U S A (2011) 1.87
Differential transactivation by the p53 transcription factor is highly dependent on p53 level and promoter target sequence. Mol Cell Biol (2002) 1.83
Insights into p53 transcriptional function via genome-wide chromatin occupancy and gene expression analysis. Cell Death Differ (2012) 1.81
Identification of polymorphic antioxidant response elements in the human genome. Hum Mol Genet (2007) 1.79
Ranked prediction of p53 targets using hidden variable dynamic modeling. Genome Biol (2006) 1.78
Portrait of transcriptional responses to ultraviolet and ionizing radiation in human cells. Nucleic Acids Res (2004) 1.68
Noncanonical DNA motifs as transactivation targets by wild type and mutant p53. PLoS Genet (2008) 1.67
Human maintenance DNA (cytosine-5)-methyltransferase and p53 modulate expression of p53-repressed promoters. Proc Natl Acad Sci U S A (2005) 1.67
Functional mutants of the sequence-specific transcription factor p53 and implications for master genes of diversity. Proc Natl Acad Sci U S A (2003) 1.63
Mechanisms of regulatory diversity within the p53 transcriptional network. Oncogene (2008) 1.57
p53-Dependent induction of PVT1 and miR-1204. J Biol Chem (2011) 1.56
Discovery and verification of functional single nucleotide polymorphisms in regulatory genomic regions: current and developing technologies. Mutat Res (2008) 1.56
Functionally distinct polymorphic sequences in the human genome that are targets for p53 transactivation. Proc Natl Acad Sci U S A (2005) 1.49
Mutant p53 cooperates with ETS2 to promote etoposide resistance. Genes Dev (2012) 1.47
p21 delays tumor onset by preservation of chromosomal stability. Proc Natl Acad Sci U S A (2006) 1.41
p63 and p73 transcriptionally regulate genes involved in DNA repair. PLoS Genet (2009) 1.41
Profiles of global gene expression in ionizing-radiation-damaged human diploid fibroblasts reveal synchronization behind the G1 checkpoint in a G0-like state of quiescence. Environ Health Perspect (2006) 1.34
Dissection of a DNA-damage-induced transcriptional network using a combination of microarrays, RNA interference and computational promoter analysis. Genome Biol (2005) 1.31
Transcriptional repression of epithelial cell adhesion molecule contributes to p53 control of breast cancer invasion. Cancer Res (2009) 1.30
p53 regulates Toll-like receptor 3 expression and function in human epithelial cell lines. Mol Cell Biol (2008) 1.29
Stress-responsive sestrins link p53 with redox regulation and mammalian target of rapamycin signaling. Antioxid Redox Signal (2011) 1.29
The p53-cathepsin axis cooperates with ROS to activate programmed necrotic death upon DNA damage. Proc Natl Acad Sci U S A (2009) 1.27
Impact of Alu repeats on the evolution of human p53 binding sites. Biol Direct (2011) 1.25
p53 targets identified by protein expression profiling. Proc Natl Acad Sci U S A (2007) 1.23
Sequence analysis of p53 response-elements suggests multiple binding modes of the p53 tetramer to DNA targets. Nucleic Acids Res (2007) 1.22
Identification of the mismatch repair genes PMS2 and MLH1 as p53 target genes by using serial analysis of binding elements. Proc Natl Acad Sci U S A (2005) 1.21
Dissecting microregulation of a master regulatory network. BMC Genomics (2008) 1.18
Probing the functional impact of sequence variation on p53-DNA interactions using a novel microsphere assay for protein-DNA binding with human cell extracts. PLoS Genet (2009) 1.17
Inhibition of glycolytic enzymes mediated by pharmacologically activated p53: targeting Warburg effect to fight cancer. J Biol Chem (2011) 1.16
p53 responsive elements in human retrotransposons. Oncogene (2009) 1.15
Chromatin immunoprecipitation-based screen to identify functional genomic binding sites for sequence-specific transactivators. Mol Cell Biol (2005) 1.15
Upregulation of annexin A1 expression by butyrate in human colon adenocarcinoma cells: role of p53, NF-Y, and p38 mitogen-activated protein kinase. Mol Cell Biol (2008) 1.12
p53 isoform Δ113p53/Δ133p53 promotes DNA double-strand break repair to protect cell from death and senescence in response to DNA damage. Cell Res (2015) 1.11
Versatile functions of p53 protein in multicellular organisms. Biochemistry (Mosc) (2007) 1.11
Glioma oncoprotein Bcl2L12 inhibits the p53 tumor suppressor. Genes Dev (2010) 1.11
Siah-1b is a direct transcriptional target of p53: identification of the functional p53 responsive element in the siah-1b promoter. Proc Natl Acad Sci U S A (2004) 1.10
Characterization of the p53 cistrome--DNA binding cooperativity dissects p53's tumor suppressor functions. PLoS Genet (2013) 1.08
E3 ubiquitin ligase TRIM32 negatively regulates tumor suppressor p53 to promote tumorigenesis. Cell Death Differ (2014) 1.07
p53-mediated transcriptional regulation and activation of the actin cytoskeleton regulatory RhoC to LIMK2 signaling pathway promotes cell survival. Cell Res (2010) 1.06
Sequence-dependent cooperative binding of p53 to DNA targets and its relationship to the structural properties of the DNA targets. Nucleic Acids Res (2010) 1.05
p53 regulates a mitotic transcription program and determines ploidy in normal mouse liver. Hepatology (2013) 1.05
Myosin VI is a mediator of the p53-dependent cell survival pathway. Mol Cell Biol (2006) 1.04
Analysis and synthesis of high-amplitude Cis-elements in the mammalian circadian clock. Proc Natl Acad Sci U S A (2008) 1.02
CIAP1 and the serine protease HTRA2 are involved in a novel p53-dependent apoptosis pathway in mammals. Genes Dev (2003) 1.02
JMJD6 promotes colon carcinogenesis through negative regulation of p53 by hydroxylation. PLoS Biol (2014) 1.01
Induction of PPM1D following DNA-damaging treatments through a conserved p53 response element coincides with a shift in the use of transcription initiation sites. Nucleic Acids Res (2008) 1.01
p53 and p73 display common and distinct requirements for sequence specific binding to DNA. Nucleic Acids Res (2006) 0.98
Discovery of novel tumor suppressor p53 response elements using information theory. Nucleic Acids Res (2008) 0.98
RegAnalyst: a web interface for the analysis of regulatory motifs, networks and pathways. Nucleic Acids Res (2009) 0.97
YPEL3, a p53-regulated gene that induces cellular senescence. Cancer Res (2010) 0.96
p53 induces distinct epigenetic states at its direct target promoters. BMC Genomics (2008) 0.96
Regulation of H-ras splice variant expression by cross talk between the p53 and nonsense-mediated mRNA decay pathways. Mol Cell Biol (2007) 0.96
NGF-mediated transcriptional targets of p53 in PC12 neuronal differentiation. BMC Genomics (2007) 0.93
The novel p53 target gene IRF2BP2 participates in cell survival during the p53 stress response. Nucleic Acids Res (2008) 0.92
Inhibitors of Glioma Growth that Reveal the Tumour to the Immune System. Clin Med Insights Oncol (2011) 0.92
The NAD+ synthesizing enzyme nicotinamide mononucleotide adenylyltransferase 2 (NMNAT-2) is a p53 downstream target. Cell Cycle (2014) 0.92
Serine/threonine kinase 17A is a novel p53 target gene and modulator of cisplatin toxicity and reactive oxygen species in testicular cancer cells. J Biol Chem (2011) 0.90
The tumor suppressor p53 transcriptionally regulates cGKI expression during neuronal maturation and is required for cGMP-dependent growth cone collapse. J Neurosci (2009) 0.89
Probing potential binding modes of the p53 tetramer to DNA based on the symmetries encoded in p53 response elements. Nucleic Acids Res (2007) 0.88
The p53HMM algorithm: using profile hidden markov models to detect p53-responsive genes. BMC Bioinformatics (2009) 0.88
Regression based predictor for p53 transactivation. BMC Bioinformatics (2009) 0.88
Cooperativity dominates the genomic organization of p53-response elements: a mechanistic view. PLoS Comput Biol (2009) 0.86
Dual Roles of MDM2 in the Regulation of p53: Ubiquitination Dependent and Ubiquitination Independent Mechanisms of MDM2 Repression of p53 Activity. Genes Cancer (2012) 0.85
Regional genome transcriptional response of adult mouse brain to hypoxia. BMC Genomics (2011) 0.85
Direct activation of forkhead box O3 by tumor suppressors p53 and p73 is disrupted during liver regeneration in mice. Hepatology (2010) 0.83
Effects of DNA-targeted ionizing radiation produced by 5-[125I]iodo-2'-deoxyuridine on global gene expression in primary human cells. BMC Genomics (2007) 0.83
Altered binding site selection of p53 transcription cassettes by hepatitis B virus X protein. Mol Cell Biol (2012) 0.83
P53 family members modulate the expression of PRODH, but not PRODH2, via intronic p53 response elements. PLoS One (2013) 0.83
Potential roles for prions and protein-only inheritance in cancer. Cancer Metastasis Rev (2012) 0.82
PRAP1 is a novel executor of p53-dependent mechanisms in cell survival after DNA damage. Cell Death Dis (2012) 0.81
Chk2 and p53 are haploinsufficient with dependent and independent functions to eliminate cells after telomere loss. PLoS Genet (2011) 0.81
Cell context dependent p53 genome-wide binding patterns and enrichment at repeats. PLoS One (2014) 0.80
Whole-genome cartography of p53 response elements ranked on transactivation potential. BMC Genomics (2015) 0.80
Inactivation of oncogenic cAMP-specific phosphodiesterase 4D by miR-139-5p in response to p53 activation. Elife (2016) 0.79
Conservation and implications of eukaryote transcriptional regulatory regions across multiple species. BMC Genomics (2008) 0.78
The TP53 fertility network. Genet Mol Biol (2012) 0.78
Protein-binding microarray analysis of tumor suppressor AP2α target gene specificity. PLoS One (2011) 0.78
Repression of Puma by scratch2 is required for neuronal survival during embryonic development. Cell Death Differ (2011) 0.78
TFIIS.h, a new target of p53, regulates transcription efficiency of pro-apoptotic bax gene. Sci Rep (2016) 0.78
The CEACAM1 tumor suppressor is an ATM and p53-regulated gene required for the induction of cellular senescence by DNA damage. Oncogenesis (2012) 0.78
p53 regulates the mevalonate pathway in human glioblastoma multiforme. Cell Death Dis (2015) 0.78
A PTCH1 homolog transcriptionally activated by p53 suppresses Hedgehog signaling. J Biol Chem (2014) 0.77
p53 binding to human genome: crowd control navigation in chromatin context. Front Genet (2014) 0.77
Epigenetic inactivation of the p53-induced long noncoding RNA TP53 target 1 in human cancer. Proc Natl Acad Sci U S A (2016) 0.76
P53 and the defenses against genome instability caused by transposons and repetitive elements. Bioessays (2016) 0.76
p53 directly regulates the glycosidase FUCA1 to promote chemotherapy-induced cell death. Cell Cycle (2016) 0.76
Species-specific mutual regulation of p53 and miR-138 between human, rat and mouse. Sci Rep (2016) 0.75
The Drosophila retinoblastoma binding protein 6 family member has two isoforms and is potentially involved in embryonic patterning. Int J Mol Sci (2015) 0.75
Identification of p53-target genes in Danio rerio. Sci Rep (2016) 0.75
Transglutaminase 2 contributes to a TP53-induced autophagy program to prevent oncogenic transformation. Elife (2016) 0.75
Novel p53 target genes secreted by the liver are involved in non-cell-autonomous regulation. Cell Death Differ (2015) 0.75
Post-translational regulation of p53 function through 20S proteasome-mediated cleavage. Cell Death Differ (2017) 0.75
p53, the cellular gatekeeper for growth and division. Cell (1997) 31.04
MatInd and MatInspector: new fast and versatile tools for detection of consensus matches in nucleotide sequence data. Nucleic Acids Res (1995) 21.22
Identifying protein-binding sites from unaligned DNA fragments. Proc Natl Acad Sci U S A (1989) 14.45
Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations. Science (1994) 13.51
Definition of a consensus binding site for p53. Nat Genet (1992) 12.76
p53 mutant mice that display early ageing-associated phenotypes. Nature (2002) 10.05
Trimming, weighting, and grouping SNPs in human case-control association studies. Genome Res (2001) 9.41
A transcriptionally active DNA-binding site for human p53 protein complexes. Mol Cell Biol (1992) 6.56
p53 and E2F-1 cooperate to mediate apoptosis. Proc Natl Acad Sci U S A (1994) 5.49
Regulation of PTEN transcription by p53. Mol Cell (2001) 5.44
Analysis of p53-regulated gene expression patterns using oligonucleotide arrays. Genes Dev (2000) 5.04
Specificity, free energy and information content in protein-DNA interactions. Trends Biochem Sci (1998) 5.00
Allosteric effects of Pit-1 DNA sites on long-term repression in cell type specification. Science (2000) 3.14
Topological control of p21WAF1/CIP1 expression in normal and neoplastic tissues. Cancer Res (1995) 3.13
Identification and classification of p53-regulated genes. Proc Natl Acad Sci U S A (1999) 3.07
The p53 functional circuit. J Cell Sci (2001) 2.46
Scan statistics to scan markers for susceptibility genes. Proc Natl Acad Sci U S A (2000) 1.73
Relief of p53-mediated transcriptional repression by the adenovirus E1B 19-kDa protein or the cellular Bcl-2 protein. Proc Natl Acad Sci U S A (1994) 1.69
A functionally inactive p53 protein in teratocarcinoma cells is activated by either DNA damage or cellular differentiation. Nat Med (1996) 1.67
p53CP, a putative p53 competing protein that specifically binds to the consensus p53 DNA binding sites: a third member of the p53 family? Proc Natl Acad Sci U S A (1997) 1.18
Binding to the naturally occurring double p53 binding site of the Mdm2 promoter alleviates the requirement for p53 C-terminal activation. Nucleic Acids Res (2001) 1.01
The sequence of the human genome. Science (2001) 101.55
Multilocus linkage analysis in humans: detection of linkage and estimation of recombination. Am J Hum Genet (1985) 87.59
Strategies for multilocus linkage analysis in humans. Proc Natl Acad Sci U S A (1984) 48.41
Surfing the p53 network. Nature (2000) 35.36
Broad patterns of gene expression revealed by clustering analysis of tumor and normal colon tissues probed by oligonucleotide arrays. Proc Natl Acad Sci U S A (1999) 35.16
Estimation of the recombination fraction in human pedigrees: efficient computation of the likelihood for human linkage studies. Am J Hum Genet (1974) 23.66
The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53. Cell (1990) 20.60
The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation. Cell (1992) 16.53
Characterization of a 54K dalton cellular SV40 tumor antigen present in SV40-transformed cells and uninfected embryonal carcinoma cells. Cell (1979) 14.05
Association of human papillomavirus types 16 and 18 E6 proteins with p53. Science (1990) 12.88
The rapid generation of oligonucleotide-directed mutations at high frequency using phosphorothioate-modified DNA. Nucleic Acids Res (1985) 12.11
The p53 proto-oncogene can act as a suppressor of transformation. Cell (1989) 11.67
The p53-mdm-2 autoregulatory feedback loop. Genes Dev (1993) 11.19
Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain. Science (1996) 9.48
Trimming, weighting, and grouping SNPs in human case-control association studies. Genome Res (2001) 9.41
Adenovirus E1b-58kd tumor antigen and SV40 large tumor antigen are physically associated with the same 54 kd cellular protein in transformed cells. Cell (1982) 9.27
A haplotype-based 'haplotype relative risk' approach to detecting allelic associations. Hum Hered (1992) 8.71
Activating mutations for transformation by p53 produce a gene product that forms an hsc70-p53 complex with an altered half-life. Mol Cell Biol (1988) 6.44
Cellular localization and cell cycle regulation by a temperature-sensitive p53 protein. Genes Dev (1991) 6.30
Post-translational regulation of the 54K cellular tumor antigen in normal and transformed cells. Mol Cell Biol (1981) 6.02
A computer program for linkage analysis of general human pedigrees. Am J Hum Genet (1976) 6.01
Several hydrophobic amino acids in the p53 amino-terminal domain are required for transcriptional activation, binding to mdm-2 and the adenovirus 5 E1B 55-kD protein. Genes Dev (1994) 5.68
Report of the Committee on Methods of Linkage Analysis and Reporting. Cytogenet Cell Genet (1985) 5.61
p53 and E2F-1 cooperate to mediate apoptosis. Proc Natl Acad Sci U S A (1994) 5.49
Mapping of the p53 and mdm-2 interaction domains. Mol Cell Biol (1993) 5.31
Analysis of p53-regulated gene expression patterns using oligonucleotide arrays. Genes Dev (2000) 5.04
Nucleo-cytoplasmic shuttling of the hdm2 oncoprotein regulates the levels of the p53 protein via a pathway used by the human immunodeficiency virus rev protein. EMBO J (1998) 4.98
Chromosome-based method for rapid computer simulation in human genetic linkage analysis. Genet Epidemiol (1993) 4.98
Growth regulation of a cellular tumour antigen, p53, in nontransformed cells. Nature (1984) 4.86
Linkage of a prion protein missense variant to Gerstmann-Sträussler syndrome. Nature (1989) 4.69
Mutation is required to activate the p53 gene for cooperation with the ras oncogene and transformation. J Virol (1989) 4.63
Counting methods (EM algorithm) in human pedigree analysis: linkage and segregation analysis. Ann Hum Genet (1977) 4.54
Transcriptional gene expression profiles of colorectal adenoma, adenocarcinoma, and normal tissue examined by oligonucleotide arrays. Cancer Res (2001) 4.50
DNA replication in SV40 infected cells. I. Analysis of replicating SV40 DNA. J Mol Biol (1970) 4.49
Mutant p53 DNA clones from human colon carcinomas cooperate with ras in transforming primary rat cells: a comparison of the "hot spot" mutant phenotypes. Cell Growth Differ (1990) 4.32
Gain of function mutations in p53. Nat Genet (1993) 4.19
Relationship estimation in affected sib pair analysis of late-onset diseases. Eur J Hum Genet (1997) 4.16
Ku70-deficient embryonic stem cells have increased ionizing radiosensitivity, defective DNA end-binding activity, and inability to support V(D)J recombination. Proc Natl Acad Sci U S A (1997) 4.13
Wild-type p53 binds to the TATA-binding protein and represses transcription. Proc Natl Acad Sci U S A (1992) 4.06
Mapping genetic elements of Epstein-Barr virus that facilitate extrachromosomal persistence of Epstein-Barr virus-derived plasmids in human cells. Mol Cell Biol (1985) 4.03
p53 alteration is a common event in the spontaneous immortalization of primary BALB/c murine embryo fibroblasts. Genes Dev (1991) 4.01
Nuclear export is required for degradation of endogenous p53 by MDM2 and human papillomavirus E6. Mol Cell Biol (1998) 3.99
Estrogen replacement therapy for treatment of mild to moderate Alzheimer disease: a randomized controlled trial. Alzheimer's Disease Cooperative Study. JAMA (2000) 3.99
The process of infection with bacteriophage phiX174. XXV. Studies with bacteriophage phiX174 mutants blocked in progeny replicative form DNA synthesis. J Mol Biol (1969) 3.87
P19(ARF) stabilizes p53 by blocking nucleo-cytoplasmic shuttling of Mdm2. Proc Natl Acad Sci U S A (1999) 3.78
Linkage analysis and family classification under heterogeneity. Ann Hum Genet (1983) 3.76
Two-trait-locus linkage analysis: a powerful strategy for mapping complex genetic traits. Am J Hum Genet (1993) 3.76
Generation of oscillations by the p53-Mdm2 feedback loop: a theoretical and experimental study. Proc Natl Acad Sci U S A (2000) 3.74
WISP genes are members of the connective tissue growth factor family that are up-regulated in wnt-1-transformed cells and aberrantly expressed in human colon tumors. Proc Natl Acad Sci U S A (1998) 3.73
Mutations in two Ku homologs define a DNA end-joining repair pathway in Saccharomyces cerevisiae. Mol Cell Biol (1996) 3.57
Transgenic mice harboring SV40 T-antigen genes develop characteristic brain tumors. Cell (1984) 3.56
Isolation and characterization of polyoma host range mutants that replicate in nullipotential embryonal carcinoma cells. Proc Natl Acad Sci U S A (1981) 3.55
The Multicenter AIDS Cohort Study: retention after 9 1/2 years. Am J Epidemiol (1995) 3.54
Transcriptional repression by wild-type p53 utilizes histone deacetylases, mediated by interaction with mSin3a. Genes Dev (1999) 3.41
Interaction between the retinoblastoma protein and the oncoprotein MDM2. Nature (1995) 3.39
Two distinct mechanisms regulate the levels of a cellular tumor antigen, p53. Mol Cell Biol (1983) 3.39
Adenovirus early region 1B 58,000-dalton tumor antigen is physically associated with an early region 4 25,000-dalton protein in productively infected cells. J Virol (1984) 3.38
Wild-type p53 mediates positive regulation of gene expression through a specific DNA sequence element. Genes Dev (1992) 3.37
Maximum likelihood estimation by counting methods under polygenic and mixed models in human pedigrees. Am J Hum Genet (1979) 3.36
Functions of the MDM2 oncoprotein. Cell Mol Life Sci (1999) 3.35
The SV40 A gene product is required for the production of a 54,000 MW cellular tumor antigen. Virology (1979) 3.33
DNA-binding proteins specific for cells infected by adenovirus. Nat New Biol (1973) 3.30
Thermolabile DNA binding proteins from cells infected with a temperature-sensitive mutant of adenovrius defective in viral DNA synthesis. J Virol (1975) 3.29
Two distinct mechanisms alter p53 in breast cancer: mutation and nuclear exclusion. Proc Natl Acad Sci U S A (1992) 3.27
The ribosomal L5 protein is associated with mdm-2 and mdm-2-p53 complexes. Mol Cell Biol (1994) 3.16
Identification of the p53 protein domain involved in formation of the simian virus 40 large T-antigen-p53 protein complex. J Virol (1986) 3.04
Immunological evidence for the association of p53 with a heat shock protein, hsc70, in p53-plus-ras-transformed cell lines. Mol Cell Biol (1987) 3.01
A simple scheme for the analysis of HLA linkages in pedigrees. Ann Hum Genet (1978) 3.01
Conversion of the lac repressor into an allosterically regulated transcriptional activator for mammalian cells. Mol Cell Biol (1990) 3.00
Molecular abnormalities of mdm2 and p53 genes in adult soft tissue sarcomas. Cancer Res (1994) 2.98
Nucleocytoplasmic shuttling of oncoprotein Hdm2 is required for Hdm2-mediated degradation of p53. Proc Natl Acad Sci U S A (1999) 2.89
mdm-2 inhibits the G1 arrest and apoptosis functions of the p53 tumor suppressor protein. Mol Cell Biol (1996) 2.78
Report of the committee on linkage and gene order. Cytogenet Cell Genet (1989) 2.76
Human TAFII31 protein is a transcriptional coactivator of the p53 protein. Proc Natl Acad Sci U S A (1995) 2.76
Monoclonal antibodies which recognize native and denatured forms of the adenovirus DNA-binding protein. Virology (1983) 2.69
A transmission/disequilibrium test that allows for genotyping errors in the analysis of single-nucleotide polymorphism data. Am J Hum Genet (2001) 2.68
WISP-1 is a Wnt-1- and beta-catenin-responsive oncogene. Genes Dev (2000) 2.67
A monoclonal antibody detecting the adenovirus type 5-E1b-58Kd tumor antigen: characterization of the E1b-58Kd tumor antigen in adenovirus-infected and -transformed cells. Virology (1982) 2.65
Thousandfold change in resistivity in magnetoresistive la-ca-mn-o films. Science (1994) 2.64
Identification and mapping of Epstein-Barr virus early antigens and demonstration of a viral gene activator that functions in trans. J Virol (1986) 2.64
Automated high resolution optical mapping using arrayed, fluid-fixed DNA molecules. Proc Natl Acad Sci U S A (1998) 2.50
Linkage studies in a large kindred with familial hypercholesterolemia. Am J Hum Genet (1974) 2.49
A comparison of the biological activities of wild-type and mutant p53. FASEB J (1993) 2.49
Characterization of monoclonal antibodies and polyclonal immune sera directed against human cytomegalovirus virion proteins. Virology (1984) 2.48
Measuring the inflation of the lod score due to its maximization over model parameter values in human linkage analysis. Genet Epidemiol (1990) 2.47
The p53 functional circuit. J Cell Sci (2001) 2.46
Mechanism by which fiber antigen inhibits multiplication of type 5 adenovirus. J Virol (1967) 2.44
Nuclear export of the E1B 55-kDa and E4 34-kDa adenoviral oncoproteins mediated by a rev-like signal sequence. EMBO J (1997) 2.44
Regulation of transcription functions of the p53 tumor suppressor by the mdm-2 oncogene. Mol Med (1995) 2.44
Predisposition to familial osteoarthrosis linked to type II collagen gene. Lancet (1989) 2.43
Mutant p53 gain of function: differential effects of different p53 mutants on resistance of cultured cells to chemotherapy. Oncogene (1999) 2.43
Identification and characterization of an immunologically conserved adenovirus early region 11,000 Mr protein and its association with the nuclear matrix. J Mol Biol (1982) 2.36
Induced alpha helix in the VP16 activation domain upon binding to a human TAF. Science (1997) 2.35
A chimeric mammalian transactivator based on the lac repressor that is regulated by temperature and isopropyl beta-D-thiogalactopyranoside. Proc Natl Acad Sci U S A (1991) 2.35
A microsatellite genetic linkage map of human chromosome 18. Genomics (1993) 2.35
Identification of a novel p53 functional domain that is necessary for efficient growth suppression. Proc Natl Acad Sci U S A (1996) 2.30
A genomewide screen for autism susceptibility loci. Am J Hum Genet (2001) 2.30
Deoxyribonucleic acid replication in simian virus 40-infected cells. II. Detection and characterization of simian virus 40 pseudovirions. J Virol (1970) 2.30
Identification of a novel common genetic risk factor for lumbar disk disease. JAMA (2001) 2.28
DNA replication in SV40-infected cells. IX. The inhibition of a gap-filling step during discontinuous synthesis of SV40 DNA. Virology (1973) 2.27