Published in Neuropharmacology on May 01, 1999
Glutamate receptor ion channels: structure, regulation, and function. Pharmacol Rev (2010) 11.25
Interaction of the AMPA receptor subunit GluR2/3 with PDZ domains regulates hippocampal long-term depression. Proc Natl Acad Sci U S A (2001) 2.75
Regulation of synaptic strength and AMPA receptor subunit composition by PICK1. J Neurosci (2004) 2.19
The molecular pharmacology and cell biology of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors. Pharmacol Rev (2005) 1.96
Rapid and differential regulation of AMPA and kainate receptors at hippocampal mossy fibre synapses by PICK1 and GRIP. Neuron (2003) 1.95
AMPA receptor trafficking and long-term potentiation. Philos Trans R Soc Lond B Biol Sci (2003) 1.85
An essential role for PICK1 in NMDA receptor-dependent bidirectional synaptic plasticity. Neuron (2008) 1.82
Parkin-mediated monoubiquitination of the PDZ protein PICK1 regulates the activity of acid-sensing ion channels. Mol Biol Cell (2007) 1.69
Interaction of the synaptic protein PICK1 (protein interacting with C kinase 1) with the non-voltage gated sodium channels BNC1 (brain Na+ channel 1) and ASIC (acid-sensing ion channel). Biochem J (2002) 1.46
PICK1 deficiency causes male infertility in mice by disrupting acrosome formation. J Clin Invest (2009) 1.44
Calcium binding to PICK1 is essential for the intracellular retention of AMPA receptors underlying long-term depression. J Neurosci (2010) 1.34
PICK1 loss of function occludes homeostatic synaptic scaling. J Neurosci (2011) 1.26
Membrane localization is critical for activation of the PICK1 BAR domain. Traffic (2008) 1.25
Metabotropic glutamate receptor-mediated LTD involves two interacting Ca(2+) sensors, NCS-1 and PICK1. Neuron (2008) 1.24
Cellular and subcellular mRNA localization of glutamate transporter isoforms GLT1a and GLT1b in rat brain by in situ hybridization. J Comp Neurol (2005) 1.22
Clustering and synaptic targeting of PICK1 requires direct interaction between the PDZ domain and lipid membranes. EMBO J (2007) 1.20
Developmental regulation of protein interacting with C kinase 1 (PICK1) function in hippocampal synaptic plasticity and learning. Proc Natl Acad Sci U S A (2010) 1.15
Alpha7 nicotinic acetylcholine receptors occur at postsynaptic densities of AMPA receptor-positive and -negative excitatory synapses in rat sensory cortex. J Neurosci (2002) 1.12
GluR2 protein-protein interactions and the regulation of AMPA receptors during synaptic plasticity. Philos Trans R Soc Lond B Biol Sci (2003) 1.10
AMPA receptor trafficking in homeostatic synaptic plasticity: functional molecules and signaling cascades. Neural Plast (2012) 1.07
Activation of extrasynaptic NMDA receptors induces a PKC-dependent switch in AMPA receptor subtypes in mouse cerebellar stellate cells. J Physiol (2007) 1.05
Memory maintenance by PKMζ--an evolutionary perspective. Mol Brain (2012) 1.01
Interaction between the glutamate transporter GLT1b and the synaptic PDZ domain protein PICK1. Eur J Neurosci (2008) 1.00
Brain-derived neurotrophic factor signal enhances and maintains the expression of AMPA receptor-associated PDZ proteins in developing cortical neurons. Dev Biol (2003) 0.98
The X-linked intellectual disability protein TSPAN7 regulates excitatory synapse development and AMPAR trafficking. Neuron (2012) 0.98
The schizophrenic faces of PICK1. Trends Pharmacol Sci (2006) 0.94
The PDZ domain of PICK1 differentially accepts protein kinase C-alpha and GluR2 as interacting ligands. J Biol Chem (2004) 0.93
PICK1 interacts with alpha7 neuronal nicotinic acetylcholine receptors and controls their clustering. Mol Cell Neurosci (2007) 0.92
Diabetes changes the levels of ionotropic glutamate receptors in the rat retina. Mol Vis (2009) 0.91
PICK1 is implicated in organelle motility in an Arp2/3 complex-independent manner. Mol Biol Cell (2015) 0.91
Update on the neurobiology of schizophrenia: a role for extracellular microdomains. Minerva Psichiatr (2012) 0.91
AMPAR trafficking in synapse maturation and plasticity. Cell Mol Life Sci (2013) 0.91
PDZ binding to the BAR domain of PICK1 is elucidated by coarse-grained molecular dynamics. J Mol Biol (2010) 0.91
PICK1 regulates the trafficking of ASIC1a and acidotoxicity in a BAR domain lipid binding-dependent manner. Mol Brain (2010) 0.90
Transmembrane AMPA receptor regulatory protein (TARP) dysregulation in anterior cingulate cortex in schizophrenia. Schizophr Res (2013) 0.90
PICK1 interacts with PACSIN to regulate AMPA receptor internalization and cerebellar long-term depression. Proc Natl Acad Sci U S A (2013) 0.89
Proteins interactions implicated in AMPA receptor trafficking: a clear destination and an improving route map. Neurosci Res (2003) 0.89
Preserved acute pain and impaired neuropathic pain in mice lacking protein interacting with C Kinase 1. Mol Pain (2011) 0.87
Intracellular machinery for the transport of AMPA receptors. Br J Pharmacol (2007) 0.87
Glycogen Synthase Kinase 3β-mediated Phosphorylation in the Most C-terminal Region of Protein Interacting with C Kinase 1 (PICK1) Regulates the Binding of PICK1 to Glutamate Receptor Subunit GluA2. J Biol Chem (2015) 0.86
Regulation of synaptic structure and function by palmitoylated AMPA receptor binding protein. Mol Cell Neurosci (2010) 0.86
Protein interacting with C-kinase 1 (PICK1) binding promiscuity relies on unconventional PSD-95/discs-large/ZO-1 homology (PDZ) binding modes for nonclass II PDZ ligands. J Biol Chem (2014) 0.86
The BTB/kelch protein, KRIP6, modulates the interaction of PICK1 with GluR6 kainate receptors. Neuropharmacology (2008) 0.85
Involvement of GluR2 and GluR3 subunit C-termini in the trigeminal spinal subnucleus caudalis and C1-C2 neurons in trigeminal neuropathic pain. Neurosci Lett (2011) 0.84
Serine 77 in the PDZ domain of PICK1 is a protein kinase Cα phosphorylation site regulated by lipid membrane binding. Biochemistry (2012) 0.82
PKC and polyamine modulation of GluR2-deficient AMPA receptors in immature neocortical pyramidal neurons of the rat. J Physiol (2007) 0.81
Gene transfer of constitutively active protein kinase C into striatal neurons accelerates onset of levodopa-induced motor response alterations in parkinsonian rats. Brain Res (2003) 0.81
Activity-dependent synaptic GRIP1 accumulation drives synaptic scaling up in response to action potential blockade. Proc Natl Acad Sci U S A (2015) 0.80
Basic Fibroblast Growth Factor Modulates the Expression of PDZ Domain-containing Proteins in Cultured Cortical Neurons. Acta Med Biol (Niigata) (2002) 0.80
Glutamate receptor abnormalities in schizophrenia: implications for innovative treatments. Biomol Ther (Seoul) (2012) 0.80
Spatiotemporal analysis of the molecular interaction between PICK1 and PKC. Acta Histochem Cytochem (2006) 0.80
PACSIN1 regulates the dynamics of AMPA receptor trafficking. Sci Rep (2016) 0.79
Long-term synaptic plasticity in cerebellar stellate cells. Cerebellum (2008) 0.78
Syntabulin regulates the trafficking of PICK1-containing vesicles in neurons. Sci Rep (2016) 0.77
C-terminal domain of ICA69 interacts with PICK1 and acts on trafficking of PICK1-PKCα complex and cerebellar plasticity. PLoS One (2013) 0.75
Lithium increases synaptic GluA2 in hippocampal neurons by elevating the δ-catenin protein. Neuropharmacology (2016) 0.75
S-palmitoylation regulates AMPA receptors trafficking and function: a novel insight into synaptic regulation and therapeutics. Acta Pharm Sin B (2014) 0.75
Cloning and expression of a cDNA encoding an endothelin receptor. Nature (1991) 7.26
Structural basis of glutamate recognition by a dimeric metabotropic glutamate receptor. Nature (2000) 6.58
Nucleotide sequence of cloned cDNA for bovine corticotropin-beta-lipotropin precursor. Nature (1979) 6.56
Induction of midbrain dopaminergic neurons from ES cells by stromal cell-derived inducing activity. Neuron (2000) 6.33
Molecular cloning and characterization of the rat NMDA receptor. Nature (1991) 4.45
Hes1 and Hes5 as notch effectors in mammalian neuronal differentiation. EMBO J (1999) 3.95
Inhibition of histamine secretion by wortmannin through the blockade of phosphatidylinositol 3-kinase in RBL-2H3 cells. J Biol Chem (1993) 3.88
Two mammalian helix-loop-helix factors structurally related to Drosophila hairy and Enhancer of split. Genes Dev (1992) 3.85
Cloning of a membrane protein that induces a slow voltage-gated potassium current. Science (1988) 3.57
Differential presynaptic localization of metabotropic glutamate receptor subtypes in the rat hippocampus. J Neurosci (1997) 3.49
K-252 compounds, novel and potent inhibitors of protein kinase C and cyclic nucleotide-dependent protein kinases. Biochem Biophys Res Commun (1987) 3.46
cDNA cloning of bovine substance-K receptor through oocyte expression system. Nature (1987) 3.31
Targeted disruption of mammalian hairy and Enhancer of split homolog-1 (HES-1) leads to up-regulation of neural helix-loop-helix factors, premature neurogenesis, and severe neural tube defects. Genes Dev (1995) 3.29
Hypertrophic nonobstructive cardiomyopathy with giant negative T waves (apical hypertrophy): ventriculographic and echocardiographic features in 30 patients. Am J Cardiol (1979) 3.29
Refinement of odor molecule tuning by dendrodendritic synaptic inhibition in the olfactory bulb. Proc Natl Acad Sci U S A (1995) 3.26
A key role of starburst amacrine cells in originating retinal directional selectivity and optokinetic eye movement. Neuron (2001) 3.18
Cloning and sequence analysis of cDNA for porcine beta-neo-endorphin/dynorphin precursor. Nature (1982) 3.09
Sequence and expression of a metabotropic glutamate receptor. Nature (1991) 2.97
NSF binding to GluR2 regulates synaptic transmission. Neuron (1998) 2.92
Molecular characterization of a novel retinal metabotropic glutamate receptor mGluR6 with a high agonist selectivity for L-2-amino-4-phosphonobutyrate. J Biol Chem (1993) 2.80
Cloning and sequence analysis of cDNA for bovine adrenal preproenkephalin. Nature (1982) 2.79
Hippocampal LTD expression involves a pool of AMPARs regulated by the NSF-GluR2 interaction. Neuron (1999) 2.60
PDZ proteins interacting with C-terminal GluR2/3 are involved in a PKC-dependent regulation of AMPA receptors at hippocampal synapses. Neuron (2000) 2.56
A family of metabotropic glutamate receptors. Neuron (1992) 2.38
Persistent expression of helix-loop-helix factor HES-1 prevents mammalian neural differentiation in the central nervous system. EMBO J (1994) 2.35
Urinary excretion of aquaporin-2 in patients with diabetes insipidus. N Engl J Med (1995) 2.33
A mammalian helix-loop-helix factor structurally related to the product of Drosophila proneural gene atonal is a positive transcriptional regulator expressed in the developing nervous system. J Biol Chem (1995) 2.31
Cloning and expression of cDNA for a human thromboxane A2 receptor. Nature (1991) 2.26
Structure, chromosomal locus, and promoter analysis of the gene encoding the mouse helix-loop-helix factor HES-1. Negative autoregulation through the multiple N box elements. J Biol Chem (1994) 2.26
Mammalian hairy and Enhancer of split homolog 1 regulates differentiation of retinal neurons and is essential for eye morphogenesis. Neuron (1996) 2.22
Molecular characterization of a novel metabotropic glutamate receptor mGluR5 coupled to inositol phosphate/Ca2+ signal transduction. J Biol Chem (1992) 2.21
Helix-loop-helix factors in growth and differentiation of the vertebrate nervous system. Curr Opin Genet Dev (1997) 2.20
Developmentally regulated postsynaptic localization of a metabotropic glutamate receptor in rat rod bipolar cells. Cell (1994) 2.20
Structure and functional expression of the cloned rat neurotensin receptor. Neuron (1990) 2.18
Structural organization of the human kininogen gene and a model for its evolution. J Biol Chem (1985) 2.14
Immunohistochemical localization of a metabotropic glutamate receptor, mGluR5, in the rat brain. Neurosci Lett (1993) 2.10
Tissue-specific generation of two preprotachykinin mRNAs from one gene by alternative RNA splicing. Nature (1985) 2.05
Surface expression of AMPA receptors in hippocampal neurons is regulated by an NSF-dependent mechanism. Neuron (1999) 2.00
Structural analysis of repetitive DNA sequences in the bovine corticotropin-beta-lipotropin precursor gene region. Nucleic Acids Res (1982) 1.99
Xenopus Zic-related-1 and Sox-2, two factors induced by chordin, have distinct activities in the initiation of neural induction. Development (1998) 1.99
Block of Ca2+ wave and Ca2+ oscillation by antibody to the inositol 1,4,5-trisphosphate receptor in fertilized hamster eggs. Science (1992) 1.99
A putative Ca2+-binding protein: structure of the light subunit of porcine calpain elucidated by molecular cloning and protein sequence analysis. Proc Natl Acad Sci U S A (1985) 1.99
Nucleotide sequences of cloned cDNAs for two types of bovine brain substance P precursor. Nature (1983) 1.98
Activation of transcription at specific promoters by glycerol. J Biol Chem (1974) 1.95
The bHLH gene Hes1 is essential for expansion of early T cell precursors. Genes Dev (1999) 1.95
Molecular characterization of a rat negative regulator with a basic helix-loop-helix structure predominantly expressed in the developing nervous system. J Biol Chem (1992) 1.93
Molecular characterization of a functional cDNA for rat substance P receptor. J Biol Chem (1989) 1.91
Labeling neural cells using adenoviral gene transfer of membrane-targeted GFP. Neuron (1996) 1.91
PSD-95 promotes Fyn-mediated tyrosine phosphorylation of the N-methyl-D-aspartate receptor subunit NR2A. Proc Natl Acad Sci U S A (1999) 1.89
Requirement of Sox2-mediated signaling for differentiation of early Xenopus neuroectoderm. Development (2000) 1.83
Induction of LTP in the hippocampus needs synaptic activation of glutamate metabotropic receptors. Nature (1993) 1.81
Impairment of hippocampal mossy fiber LTD in mice lacking mGluR2. Science (1996) 1.81
A novel ATP-dependent inward rectifier potassium channel expressed predominantly in glial cells. J Biol Chem (1995) 1.81
Differential expression of five N-methyl-D-aspartate receptor subunit mRNAs in the cerebellum of developing and adult rats. J Comp Neurol (1994) 1.80
Distribution of the mRNA for a metabotropic glutamate receptor (mGluR1) in the central nervous system: an in situ hybridization study in adult and developing rat. J Comp Neurol (1992) 1.76
Paraneoplastic cerebellar ataxia due to autoantibodies against a glutamate receptor. N Engl J Med (2000) 1.76
Distribution of the mRNA for a metabotropic glutamate receptor (mGluR3) in the rat brain: an in situ hybridization study. J Comp Neurol (1993) 1.74
Signal transduction and pharmacological characteristics of a metabotropic glutamate receptor, mGluR1, in transfected CHO cells. Neuron (1992) 1.74
Isolation and structural organization of the human preproenkephalin gene. Nature (1982) 1.73
Primary structure of human preangiotensinogen deduced from the cloned cDNA sequence. Biochemistry (1984) 1.73
Characterization of the env gene and long terminal repeat of molecularly cloned Friend mink cell focus-inducing virus DNA. J Virol (1984) 1.71
Mammalian achaete-scute and atonal homologs regulate neuronal versus glial fate determination in the central nervous system. EMBO J (2000) 1.71
Distribution of the messenger RNA for a metabotropic glutamate receptor, mGluR2, in the central nervous system of the rat. Neuroscience (1993) 1.69
Ablation of cerebellar Golgi cells disrupts synaptic integration involving GABA inhibition and NMDA receptor activation in motor coordination. Cell (1998) 1.69
Structures and properties of seven isoforms of the NMDA receptor generated by alternative splicing. Biochem Biophys Res Commun (1992) 1.67
Purification of rat liver acetyl coenzyme A carboxylase and immunochemical studies on its synthesis and degradation. Eur J Biochem (1970) 1.65
Amino acid sequence of mammalian elongation factor 2 deduced from the cDNA sequence: homology with GTP-binding proteins. Proc Natl Acad Sci U S A (1986) 1.64
Signal transduction, pharmacological properties, and expression patterns of two rat metabotropic glutamate receptors, mGluR3 and mGluR4. J Neurosci (1993) 1.63
Identification of a new type of mammalian myosin heavy chain by molecular cloning. Overlap of its mRNA with preprotachykinin B mRNA. J Biol Chem (1987) 1.62
(RS)-2-chloro-5-hydroxyphenylglycine (CHPG) activates mGlu5, but no mGlu1, receptors expressed in CHO cells and potentiates NMDA responses in the hippocampus. Neuropharmacology (1997) 1.61
PICK1 interacts with and regulates PKC phosphorylation of mGLUR7. J Neurosci (2000) 1.60
Immunohistochemical localization of substance P receptor in the central nervous system of the adult rat. J Comp Neurol (1994) 1.59
Analysis of agonist and antagonist activities of phenylglycine derivatives for different cloned metabotropic glutamate receptor subtypes. J Neurosci (1994) 1.59
Regulation of glutamate release by presynaptic kainate receptors in the hippocampus. Nature (1996) 1.59
Tissue distribution of rat angiotensinogen mRNA and structural analysis of its heterogeneity. J Biol Chem (1986) 1.56
Characterization of a soluble adrenal phosphatidylinositol 4-kinase reveals wortmannin sensitivity of type III phosphatidylinositol kinases. Biochemistry (1996) 1.55
Isolation and characterization of the bovine corticotropin/beta-lipotropin precursor gene. Eur J Biochem (1981) 1.54
The protein-coding sequence of the bovine ACTH-beta-LPH precursor gene is split near the signal peptide region. Nature (1980) 1.54
Molecular characterization of a new metabotropic glutamate receptor mGluR7 coupled to inhibitory cyclic AMP signal transduction. J Biol Chem (1994) 1.54
Cloning, nucleotide sequence, and expression in Escherichia coli of the gene for poly(3-hydroxybutyrate) depolymerase from Alcaligenes faecalis. J Bacteriol (1989) 1.54
Cloning and expression of a rat neuromedin K receptor cDNA. J Biol Chem (1990) 1.52
Cloning and sequence analysis of cDNA for human renin precursor. Proc Natl Acad Sci U S A (1983) 1.51
Kainate receptors: subunits, synaptic localization and function. Trends Pharmacol Sci (1999) 1.50
Alteration of channel activities and gating by mutations of slow ISK potassium channel. J Biol Chem (1991) 1.49
In vitro repression of the transcription of gas operon by purified gal repressor. Proc Natl Acad Sci U S A (1973) 1.48
Mash1 promotes neuronal differentiation in the retina. Genes Cells (1996) 1.47
Alteration of Ca2+ permeability and sensitivity to Mg2+ and channel blockers by a single amino acid substitution in the N-methyl-D-aspartate receptor. J Biol Chem (1993) 1.46
Role of a metabotropic glutamate receptor in synaptic modulation in the accessory olfactory bulb. Nature (1993) 1.46
Control of calcium oscillations by phosphorylation of metabotropic glutamate receptors. Nature (1996) 1.43
Two types of left ventricular wall motion abnormalities with distinct clinical features in patients with hypertrophic cardiomyopathy. Eur Heart J (1993) 1.43
Expression and purification of the extracellular ligand binding region of metabotropic glutamate receptor subtype 1. J Biol Chem (1998) 1.42
Immunohistochemical localization of metabotropic glutamate receptors, mGluR2 and mGluR3, in rat cerebellar cortex. Neuron (1994) 1.42
A novel nitrite reductase gene from the cyanobacterium Plectonema boryanum. J Bacteriol (1995) 1.40
Structural similarity of bovine lung prostaglandin F synthase to lens epsilon-crystallin of the European common frog. Proc Natl Acad Sci U S A (1988) 1.39
Cryptic dimer interface and domain organization of the extracellular region of metabotropic glutamate receptor subtype 1. J Biol Chem (2000) 1.39
Effects of dimethylsulfoxide on the E. coli gal operon and on bacteriophage lambda in vivo. Cell (1974) 1.39
Synaptic integration mediated by striatal cholinergic interneurons in basal ganglia function. Science (2000) 1.38
Cloning and sequence analysis of cDNA for rat angiotensinogen. Proc Natl Acad Sci U S A (1983) 1.37