Cloning, tissue distribution, genomic organization, and functional characterization of NBC3, a new member of the sodium bicarbonate cotransporter family.

PubWeight™: 1.92‹?› | Rank: Top 3%

🔗 View Article (PMID 10347222)

Published in J Biol Chem on June 04, 1999

Authors

A Pushkin1, N Abuladze, I Lee, D Newman, J Hwang, I Kurtz

Author Affiliations

1: Division of Nephrology, Center for Health Sciences, UCLA School of Medicine, Los Angeles, California 90095-1698, USA.

Articles citing this

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature (2011) 13.25

The SLC4 family of HCO 3 - transporters. Pflugers Arch (2004) 2.73

Molecular mechanisms of cerebrospinal fluid production. Neuroscience (2004) 1.97

Molecular mechanism of pancreatic and salivary gland fluid and HCO3 secretion. Physiol Rev (2012) 1.71

The divergence, actions, roles, and relatives of sodium-coupled bicarbonate transporters. Physiol Rev (2013) 1.50

Modular structure of sodium-coupled bicarbonate transporters. J Exp Biol (2009) 1.46

Characterization of human SLC4A10 as an electroneutral Na/HCO3 cotransporter (NBCn2) with Cl- self-exchange activity. J Biol Chem (2008) 1.41

The SLC4 family of bicarbonate (HCO₃⁻) transporters. Mol Aspects Med (2013) 1.28

Functional diversity of electrogenic Na+-HCO3- cotransport in ventricular myocytes from rat, rabbit and guinea pig. J Physiol (2004) 1.17

Novel amiloride-sensitive sodium-dependent proton secretion in the mouse proximal convoluted tubule. J Clin Invest (2000) 1.16

Basolateral Na+-dependent HCO3- transporter NBCn1-mediated HCO3- influx in rat medullary thick ascending limb. J Physiol (2003) 1.13

S0859, an N-cyanosulphonamide inhibitor of sodium-bicarbonate cotransport in the heart. Br J Pharmacol (2008) 1.09

The stoichiometry of the electrogenic sodium bicarbonate cotransporter pNBC1 in mouse pancreatic duct cells is 2 HCO(3)(-):1 Na(+). J Physiol (2001) 1.09

Na-coupled bicarbonate transporters of the solute carrier 4 family in the nervous system: function, localization, and relevance to neurologic function. Neuroscience (2010) 0.98

The electrogenicity of the rat sodium-bicarbonate cotransporter NBCe1 requires interactions among transmembrane segments of the transporter. J Physiol (2006) 0.96

Human skeletal muscle and erythrocyte proteins involved in acid-base homeostasis: adaptations to chronic hypoxia. J Physiol (2003) 0.96

Evidence of genetic effects on blood lead concentration. Environ Health Perspect (2007) 0.95

Discovery of novel glucose-regulated proteins in isolated human pancreatic islets using LC-MS/MS-based proteomics. J Proteome Res (2012) 0.94

Critical amino acid residues involved in the electrogenic sodium-bicarbonate cotransporter kNBC1-mediated transport. J Physiol (2005) 0.93

ENaC inhibition stimulates Cl- secretion in the mouse cortical collecting duct through an NKCC1-dependent mechanism. Am J Physiol Renal Physiol (2012) 0.93

Role of an extracellular loop in determining the stoichiometry of Na+-HCO₃⁻ cotransporters. J Physiol (2011) 0.92

Molecular mechanisms of electrogenic sodium bicarbonate cotransport: structural and equilibrium thermodynamic considerations. J Membr Biol (2004) 0.92

SLC4 family transporters in a marine diatom directly pump bicarbonate from seawater. Proc Natl Acad Sci U S A (2013) 0.91

Cation-coupled bicarbonate transporters. Compr Physiol (2014) 0.89

Splice cassette II of Na+,HCO3(-) cotransporter NBCn1 (slc4a7) interacts with calcineurin A: implications for transporter activity and intracellular pH control during rat artery contractions. J Biol Chem (2013) 0.89

Na(+)-dependent transporters mediate HCO(3)(-) salvage across the luminal membrane of the main pancreatic duct. J Clin Invest (2000) 0.89

The electrogenic Na+/HCO3- cotransport modulates resting membrane potential and action potential duration in cat ventricular myocytes. J Physiol (2006) 0.87

A biophysical model for integration of electrical, osmotic, and pH regulation in the human bronchial epithelium. Biophys J (2010) 0.86

Antibodies against the cardiac sodium/bicarbonate co-transporter (NBCe1) as pharmacological tools. Br J Pharmacol (2011) 0.86

A novel sodium bicarbonate cotransporter-like gene in an ancient duplicated region: SLC4A9 at 5q31. Genome Biol (2001) 0.86

The electroneutral sodium/bicarbonate cotransporter containing an amino terminal 123-amino-acid cassette is expressed predominantly in the heart. J Biomed Sci (2006) 0.86

Muscarinic receptor-induced acidification in sublingual mucous acinar cells: loss of pH recovery in Na+-H+ exchanger-1 deficient mice. J Physiol (2000) 0.84

SLC4A transporters. Curr Top Membr (2012) 0.82

Effects of optional structural elements, including two alternative amino termini and a new splicing cassette IV, on the function of the sodium-bicarbonate cotransporter NBCn1 (SLC4A7). J Physiol (2013) 0.81

PSD-95 interacts with NBCn1 and enhances channel-like activity without affecting Na/HCO(3) cotransport. Cell Physiol Biochem (2012) 0.81

Expression and distribution of NBCn2 (Slc4a10) splice variants in mouse brain: cloning of novel variant NBCn2-D. Brain Res (2011) 0.81

Structure and Function of SLC4 Family [Formula: see text] Transporters. Front Physiol (2015) 0.80

Effects of Nt-truncation and coexpression of isolated Nt domains on the membrane trafficking of electroneutral Na+/HCO3- cotransporters. Sci Rep (2015) 0.79

Effect of simultaneously replacing putative TM6 and TM12 of human NBCe1-A with those from NBCn1 on surface abundance in Xenopus oocytes. J Membr Biol (2012) 0.79

Molecular and functional evidence for a Na(+)-HCO3(-)-cotransporter in sheep ruminal epithelium. J Comp Physiol B (2003) 0.76

A pituitary gene encodes a protein that produces differentiation of breast and prostate cancer cells. Proc Natl Acad Sci U S A (2004) 0.76

Mathematical modeling of acid-base physiology. Prog Biophys Mol Biol (2015) 0.76

Direct evidence for calcineurin binding to the exon-7 loop of the sodium-bicarbonate cotransporter NBCn1. Int J Biol Sci (2014) 0.75

Sodium-bicarbonate cotransporter NBCn1/Slc4a7 inhibits NH4Cl-mediated inward current in Xenopus oocytes. Exp Physiol (2011) 0.75

Critical role of bicarbonate and bicarbonate transporters in cardiac function. World J Biol Chem (2014) 0.75

Identification of functionally distinct Na-HCO3 co-transporters in colon. PLoS One (2013) 0.75

Articles by these authors

Fourth International Consultation on Incontinence Recommendations of the International Scientific Committee: Evaluation and treatment of urinary incontinence, pelvic organ prolapse, and fecal incontinence. Neurourol Urodyn (2010) 4.48

The AGAMOUS-LIKE 20 MADS domain protein integrates floral inductive pathways in Arabidopsis. Genes Dev (2000) 3.90

LEAFY expression and flower initiation in Arabidopsis. Development (1997) 3.71

Dissociating hippocampal subregions: double dissociation between dentate gyrus and CA1. Hippocampus (2001) 3.42

A genetic framework for floral patterning. Nature (1998) 3.42

SPP1 genotype is a determinant of disease severity in Duchenne muscular dystrophy. Neurology (2010) 3.37

Plasma cell dyscrasia with polyneuropathy, organomegaly, endocrinopathy, M protein, and skin changes: the POEMS syndrome. Report on two cases and a review of the literature. Medicine (Baltimore) (1980) 3.20

Multiple DNA fragment polymorphisms associated with immunoglobulin mu chain switch-like regions in man. Proc Natl Acad Sci U S A (1983) 3.07

Multiple drug-resistant human KB carcinoma cells independently selected for high-level resistance to colchicine, adriamycin, or vinblastine show changes in expression of specific proteins. J Biol Chem (1986) 2.93

Functional domains of Pseudomonas exotoxin identified by deletion analysis of the gene expressed in E. coli. Cell (1987) 2.93

Prevalence and magnitude of perinatal substance exposures in California. N Engl J Med (1993) 2.42

Modulating autoimmune responses to GAD inhibits disease progression and prolongs islet graft survival in diabetes-prone mice. Nat Med (1996) 2.35

Diagnosis and management of infections involving implantable electrophysiologic cardiac devices. Ann Intern Med (2000) 2.30

Identification of CD72 as a lymphocyte receptor for the class IV semaphorin CD100: a novel mechanism for regulating B cell signaling. Immunity (2000) 2.16

The impairment of health-related quality of life in patients with intermittent atrial fibrillation: implications for the assessment of investigational therapy. J Am Coll Cardiol (2000) 2.00

Comparative genomics of the human and mouse T cell receptor loci. Immunity (2001) 1.92

Cultivable anaerobic microbiota of severe early childhood caries. J Clin Microbiol (2011) 1.85

Practice parameter: the care of the patient with amyotrophic lateral sclerosis (an evidence-based review): report of the Quality Standards Subcommittee of the American Academy of Neurology: ALS Practice Parameters Task Force. Neurology (1999) 1.83

Diffusion-weighted MR imaging derived apparent diffusion coefficient is predictive of clinical outcome in primary central nervous system lymphoma. AJNR Am J Neuroradiol (2009) 1.83

New-onset atrial fibrillation: sex differences in presentation, treatment, and outcome. Circulation (2001) 1.83

Molecular cloning, chromosomal localization, tissue distribution, and functional expression of the human pancreatic sodium bicarbonate cotransporter. J Biol Chem (1998) 1.83

Saccharomyces cerevisiae RAI1 (YGL246c) is homologous to human DOM3Z and encodes a protein that binds the nuclear exoribonuclease Rat1p. Mol Cell Biol (2000) 1.82

Increased T cell autoreactivity in the absence of CD40-CD40 ligand interactions: a role of CD40 in regulatory T cell development. J Immunol (2001) 1.80

The mouse mammary tumor virus long terminal repeat directs expression in epithelial and lymphoid cells of different tissues in transgenic mice. J Virol (1987) 1.75

Use of base in the treatment of severe acidemic states. Am J Kidney Dis (2001) 1.75

Report of the United States cooperative study of extracorporeal shock wave lithotripsy. J Urol (1986) 1.74

Mitochondrial energy metabolism is regulated via nuclear-coded subunits of cytochrome c oxidase. Free Radic Biol Med (2000) 1.71

Methods for injury surveillance in international cricket. J Sci Med Sport (2005) 1.69

A genetic linkage map of the baboon (Papio hamadryas) genome based on human microsatellite polymorphisms. Genomics (2000) 1.66

Identification of the low density lipoprotein receptor-binding site in apolipoprotein B100 and the modulation of its binding activity by the carboxyl terminus in familial defective apo-B100. J Clin Invest (1998) 1.59

Interaction of human Ku70 with TRF2. FEBS Lett (2000) 1.55

Giant scrotal lipomatosis. J Urol (1996) 1.55

A MATE family multidrug efflux transporter pumps out fluoroquinolones in Bacteroides thetaiotaomicron. Antimicrob Agents Chemother (2001) 1.55

Extracorporeal shock wave lithotripsy: the Methodist Hospital of Indiana experience. J Urol (1986) 1.53

Scintigraphic assessment of sympathetic innervation after transmural versus nontransmural myocardial infarction. J Am Coll Cardiol (1991) 1.52

Cytochrome C oxidase and the regulation of oxidative phosphorylation. Chembiochem (2001) 1.52

Synaptophysin expression in neuroendocrine neoplasms as determined by immunocytochemistry. Am J Pathol (1987) 1.51

26 S proteasome-mediated degradation of topoisomerase II cleavable complexes. J Biol Chem (2001) 1.50

The prevalence and nature of podiatric problems in elderly diabetic patients. J Am Geriatr Soc (1991) 1.49

Flowering-time genes modulate the response to LEAFY activity. Genetics (1998) 1.45

Effect of physiological mechanical perturbations on intact human myocardial repolarization. Cardiovasc Res (2000) 1.45

Hepatic hyperplasia in noncirrhotic fatty livers: is obesity-related hepatic steatosis a premalignant condition? Cancer Res (2001) 1.42

Immunolocalization of electrogenic sodium-bicarbonate cotransporters pNBC1 and kNBC1 in the rat eye. Am J Physiol Renal Physiol (2001) 1.41

The painful shoulder: Part I. Extrinsic disorders. Am Fam Physician (1991) 1.40

Production and release of proopiomelanocortin (POMC) derived peptides by human melanocytes and keratinocytes in culture: regulation by ultraviolet B. Biochim Biophys Acta (1996) 1.39

Methods for injury surveillance in international cricket. Br J Sports Med (2005) 1.38

Variability of acoustic segment durations after prolonged-speech treatment for stuttering. J Speech Hear Res (1992) 1.38

Biochemical and cytotoxic characteristics of an in vivo circulating oxidized low density lipoprotein (LDL-). J Lipid Res (1994) 1.36

SQUID-based microwave cavity search for dark-matter axions. Phys Rev Lett (2010) 1.36

HIV-1 tat binds TAFII250 and represses TAFII250-dependent transcription of major histocompatibility class I genes. Proc Natl Acad Sci U S A (1998) 1.36

Serum CA19-9 response as a surrogate for clinical outcome in patients receiving fixed-dose rate gemcitabine for advanced pancreatic cancer. Br J Cancer (2005) 1.34

Neuroendocrine (Merkel) cells of the skin: hyperplasias, dysplasias, and neoplasms. Lab Invest (1985) 1.33

EGF-induced mitogenesis in proximal tubular cells: potentiation by angiotensin II. Am J Physiol (1987) 1.32

Identification of the principal proteoglycan-binding site in LDL. A single-point mutation in apo-B100 severely affects proteoglycan interaction without affecting LDL receptor binding. J Clin Invest (1998) 1.32

pH-induced microtubule-dependent redistribution of late endosomes in neuronal and epithelial cells. J Cell Biol (1991) 1.31

Additional sex combs-like 1 belongs to the enhancer of trithorax and polycomb group and genetically interacts with Cbx2 in mice. Dev Biol (2009) 1.30

Treponemal antigen in immunopathogenesis of syphilitic glomerulonephritis. Am J Pathol (1976) 1.28

Identification and characterization of a human cDNA homologous to yeast SKI2. Genomics (1995) 1.27

The stoichiometry of the electrogenic sodium bicarbonate cotransporter NBC1 is cell-type dependent. J Physiol (2001) 1.26

Effect of influenza vaccination on viral replication and immune response in persons infected with human immunodeficiency virus receiving potent antiretroviral therapy. J Infect Dis (2000) 1.26

Dynamics and unfolding pathways of a hyperthermophilic and a mesophilic rubredoxin. Protein Sci (1997) 1.25

Role of NBCe1 and AE2 in secretory ameloblasts. J Dent Res (2008) 1.25

Preparation and properties of pure tubulin S. Cell Motil Cytoskeleton (1999) 1.24

Role of gender and personality on quality-of-life impairment in intermittent atrial fibrillation. Am J Cardiol (2000) 1.22

Early switch from intravenous to oral antibiotics and early hospital discharge: a prospective observational study of 200 consecutive patients with community-acquired pneumonia. Arch Intern Med (1999) 1.21

Deformability of poly(amidoamine) dendrimers. Eur Phys J E Soft Matter (2004) 1.21

Human fibroblasts bind directly to fibrinogen at RGD sites through integrin alpha(v)beta3. Exp Cell Res (1997) 1.19

Generation of a lymphocyte growth factor by treatment of human cells with neuraminidase and galactose oxidase. J Exp Med (1980) 1.18

Structural organization of the human NBC1 gene: kNBC1 is transcribed from an alternative promoter in intron 3. Gene (2000) 1.18

Human Ku70 interacts with heterochromatin protein 1alpha. J Biol Chem (2000) 1.17

Activation of basolateral amygdala corticotropin-releasing factor 1 receptors modulates the consolidation of contextual fear. Neuroscience (2007) 1.16

p53 gene status modulates the chemosensitivity of non-small cell lung cancer cells. J Biomed Sci (2000) 1.16

Persistence of ferroelectricity in BaTiO3 through the insulator-metal transition. Phys Rev Lett (2010) 1.15

Structure-function analysis of BfpB, a secretin-like protein encoded by the bundle-forming-pilus operon of enteropathogenic Escherichia coli. J Bacteriol (2001) 1.15

Effect of diet on plasma acid-base composition in normal humans. Kidney Int (1983) 1.14

Establishment and characterization of a neuroendocrine skin carcinoma cell line. Lab Invest (1987) 1.12

The Canadian Registry of Atrial Fibrillation: a noninterventional follow-up of patients after the first diagnosis of atrial fibrillation. Am J Cardiol (1998) 1.12

A cell cycle-regulated adenine DNA methyltransferase from Caulobacter crescentus processively methylates GANTC sites on hemimethylated DNA. Proc Natl Acad Sci U S A (1998) 1.11

Effect of angiotensin II induced hypertension on tumor blood flow and interstitial fluid pressure. Cancer Res (1993) 1.09

Coexpression of neuroendocrine markers and epithelial cytoskeletal proteins in bronchopulmonary neuroendocrine neoplasms. Lab Invest (1985) 1.09

Hyperaldosteronism and sudden cardiac death. Am J Cardiol (1996) 1.09

LDL- is a lipid hydroperoxide-enriched circulating lipoprotein. J Lipid Res (1997) 1.09

The stoichiometry of the electrogenic sodium bicarbonate cotransporter pNBC1 in mouse pancreatic duct cells is 2 HCO(3)(-):1 Na(+). J Physiol (2001) 1.09

Phosphorylation of Ser(982) in the sodium bicarbonate cotransporter kNBC1 shifts the HCO(3)(-) : Na(+) stoichiometry from 3 : 1 to 2 : 1 in murine proximal tubule cells. J Physiol (2001) 1.09

Use of protein-based standards in automated colorimetric determinations of fructosamine in serum. Clin Chem (1985) 1.08

Characterization of GTPase activity of TrmE, a member of a novel GTPase superfamily, from Thermotoga maritima. J Bacteriol (2000) 1.08

A single amino acid change in the acetylcholinesterase-like domain of thyroglobulin causes congenital goiter with hypothyroidism in the cog/cog mouse: a model of human endoplasmic reticulum storage diseases. Proc Natl Acad Sci U S A (1998) 1.08

The Arabidopsis flowering-time gene LUMINIDEPENDENS is expressed primarily in regions of cell proliferation and encodes a nuclear protein that regulates LEAFY expression. Plant J (1999) 1.08

The painful shoulder: Part II. Intrinsic disorders and impingement syndrome. Am Fam Physician (1991) 1.08

Cellular bicarbonate protects rat duodenal mucosa from acid-induced injury. J Clin Invest (2001) 1.07