PubRank

J Kuriyan

Author PubWeight™ 170.53‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Crystallographic R factor refinement by molecular dynamics. Science 1987 15.90
2 Structural mechanism for STI-571 inhibition of abelson tyrosine kinase. Science 2000 9.29
3 Crystal structure of the Src family tyrosine kinase Hck. Nature 1997 7.66
4 Crystal structure of the eukaryotic DNA polymerase processivity factor PCNA. Cell 1994 6.54
5 Three-dimensional structure of the beta subunit of E. coli DNA polymerase III holoenzyme: a sliding DNA clamp. Cell 1992 5.77
6 Binding of a high affinity phosphotyrosyl peptide to the Src SH2 domain: crystal structures of the complexed and peptide-free forms. Cell 1993 5.47
7 Structure of the C-terminal region of p21(WAF1/CIP1) complexed with human PCNA. Cell 1996 5.38
8 Crystallographic analysis of the recognition of a nuclear localization signal by the nuclear import factor karyopherin alpha. Cell 1998 5.27
9 Molecular dynamics and protein function. Proc Natl Acad Sci U S A 2005 4.70
10 The structural basis of the activation of Ras by Sos. Nature 1998 4.50
11 Crystal structure of the phosphotyrosine recognition domain SH2 of v-src complexed with tyrosine-phosphorylated peptides. Nature 1992 4.46
12 Activation of the Src-family tyrosine kinase Hck by SH3 domain displacement. Nature 1997 4.26
13 Crystal structure of the conserved core of HIV-1 Nef complexed with a Src family SH3 domain. Cell 1996 3.88
14 Crystal structure of a tyrosine phosphorylated STAT-1 dimer bound to DNA. Cell 1998 3.79
15 Three-dimensional structure of the catalytic subunit of protein serine/threonine phosphatase-1. Nature 1995 3.77
16 Crystal structure of Hck in complex with a Src family-selective tyrosine kinase inhibitor. Mol Cell 1999 3.73
17 X-ray structure and refinement of carbon-monoxy (Fe II)-myoglobin at 1.5 A resolution. J Mol Biol 1986 3.49
18 Crystal structure of the cytoplasmic domain of the type I TGF beta receptor in complex with FKBP12. Cell 1999 3.47
19 Crystal structure of the nucleotide exchange factor GrpE bound to the ATPase domain of the molecular chaperone DnaK. Science 1997 3.31
20 Dynamic coupling between the SH2 and SH3 domains of c-Src and Hck underlies their inactivation by C-terminal tyrosine phosphorylation. Cell 2001 3.25
21 The TGF beta receptor activation process: an inhibitor- to substrate-binding switch. Mol Cell 2001 2.87
22 High resolution crystal structure of a paired (Pax) class cooperative homeodomain dimer on DNA. Cell 1995 2.78
23 Crystal structure of the processivity clamp loader gamma (gamma) complex of E. coli DNA polymerase III. Cell 2001 2.68
24 Crystallographic analysis of the specific yet versatile recognition of distinct nuclear localization signals by karyopherin alpha. Structure 2000 2.57
25 Structures of Src-family tyrosine kinases. Curr Opin Struct Biol 1997 2.56
26 Mechanism of processivity clamp opening by the delta subunit wrench of the clamp loader complex of E. coli DNA polymerase III. Cell 2001 2.39
27 Crystal structure of the DsbA protein required for disulphide bond formation in vivo. Nature 1993 2.27
28 Thermal expansion of a protein. Biochemistry 1987 2.25
29 Crystal structure of Escherichia coli thioredoxin reductase refined at 2 A resolution. Implications for a large conformational change during catalysis. J Mol Biol 1994 2.23
30 DNA binding of in vitro activated Stat1 alpha, Stat1 beta and truncated Stat1: interaction between NH2-terminal domains stabilizes binding of two dimers to tandem DNA sites. EMBO J 1996 2.18
31 Effect of anisotropy and anharmonicity on protein crystallographic refinement. An evaluation by molecular dynamics. J Mol Biol 1986 2.16
32 Crystal structure of the delta' subunit of the clamp-loader complex of E. coli DNA polymerase III. Cell 1997 2.16
33 Crystal structure of the atypical protein kinase domain of a TRP channel with phosphotransferase activity. Mol Cell 2001 2.12
34 A single amino acid in the SH3 domain of Hck determines its high affinity and specificity in binding to HIV-1 Nef protein. EMBO J 1995 2.10
35 Structural basis for the autoinhibition of calcium/calmodulin-dependent protein kinase I. Cell 1996 2.09
36 Crystal structure of the DNA polymerase processivity factor of T4 bacteriophage. J Mol Biol 2000 2.02
37 Structure of the amino-terminal protein interaction domain of STAT-4. Science 1998 2.00
38 Crystal structure of the Dbl and pleckstrin homology domains from the human Son of sevenless protein. Cell 1998 1.77
39 Structural basis for the specific interaction of lysine-containing proline-rich peptides with the N-terminal SH3 domain of c-Crk. Structure 1995 1.76
40 Structure-based mutagenesis reveals distinct functions for Ras switch 1 and switch 2 in Sos-catalyzed guanine nucleotide exchange. J Biol Chem 2001 1.71
41 Challenges at the frontiers of structural biology. Trends Cell Biol 1999 1.62
42 Crystal structure of an archaebacterial DNA polymerase. Structure 1999 1.49
43 Sequence-specific recognition of the internalization motif of the Alzheimer's amyloid precursor protein by the X11 PTB domain. EMBO J 1997 1.48
44 Temperature dependence of the structure and dynamics of myoglobin. A simulation approach. J Mol Biol 1990 1.46
45 Crystal structures of peptide complexes of the amino-terminal SH2 domain of the Syp tyrosine phosphatase. Structure 1994 1.43
46 The influence of the proliferating cell nuclear antigen-interacting domain of p21(CIP1) on DNA synthesis catalyzed by the human and Saccharomyces cerevisiae polymerase delta holoenzymes. J Biol Chem 1997 1.42
47 Reciprocal regulation of Hck activity by phosphorylation of Tyr(527) and Tyr(416). Effect of introducing a high affinity intramolecular SH2 ligand. J Biol Chem 2000 1.41
48 A TOPRIM domain in the crystal structure of the catalytic core of Escherichia coli primase confirms a structural link to DNA topoisomerases. J Mol Biol 2000 1.30
49 Intramolecular regulatory interactions in the Src family kinase Hck probed by mutagenesis of a conserved tryptophan residue. J Biol Chem 1998 1.28
50 Clamp loader structure predicts the architecture of DNA polymerase III holoenzyme and RFC. Curr Biol 2001 1.16
51 Engineering the substrate specificity of glutathione reductase toward that of trypanothione reduction. Proc Natl Acad Sci U S A 1991 1.09
52 Crystallization of proliferating cell nuclear antigen (PCNA) from Saccharomyces cerevisiae. J Mol Biol 1994 1.07
53 Crystallization of DsbA, an Escherichia coli protein required for disulphide bond formation in vivo. J Mol Biol 1993 1.02
54 Thermus thermophilis dnaX homolog encoding gamma- and tau-like proteins of the chromosomal replicase. J Biol Chem 1997 0.94
55 The sliding clamp of DNA polymerase III holoenzyme encircles DNA. Mol Biol Cell 1992 0.88
56 An SH2 domain in disguise. Nature 1999 0.78
57 Molecular dynamics: applications to proteins. Cold Spring Harb Symp Quant Biol 1987 0.76
58 Transcription factors. DNA recognition, warts and all. Nature 1992 0.75
59 The x-ray structure of flavohemoglobin. A semisynthetic hydroxylase. J Am Chem Soc 1988 0.75
60 Paul Sigler (1934-2000). Trends Biochem Sci 2000 0.75
61 Cell science and protein crystal growth research for the International Space Station. J Cell Biochem 2000 0.75
62 Peptide recognition mechanisms of eukaryotic signaling modules. Methods Mol Biol 1998 0.75
63 Tribal health programme. Health Popul Perspect Issues 1983 0.75