D I Stuart

Author PubWeight™ 175.90‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 ESPript: analysis of multiple sequence alignments in PostScript. Bioinformatics 1999 21.85
2 The atomic structure of the bluetongue virus core. Nature 1998 4.27
3 A mechanism for initiating RNA-dependent RNA polymerization. Nature 2001 3.99
4 Crystal structure of cat muscle pyruvate kinase at a resolution of 2.6 A. J Mol Biol 1979 3.88
5 Efficient infection of cells in culture by type O foot-and-mouth disease virus requires binding to cell surface heparan sulfate. J Virol 1996 3.12
6 Crystal structure at 2.8 A resolution of a soluble form of the cell adhesion molecule CD2. Nature 1992 2.76
7 Structure of tumour necrosis factor. Nature 1989 2.62
8 Crystal structure of SIV matrix antigen and implications for virus assembly. Nature 1995 2.59
9 Crystal structure of the complex between human CD8alpha(alpha) and HLA-A2. Nature 1997 2.41
10 Structure and dimerization of a soluble form of B7-1. Immunity 2000 2.33
11 Complexes of HIV-1 reverse transcriptase with inhibitors of the HEPT series reveal conformational changes relevant to the design of potent non-nucleoside inhibitors. J Med Chem 1996 2.29
12 The structure and function of a foot-and-mouth disease virus-oligosaccharide receptor complex. EMBO J 1999 2.28
13 Structural changes in glycogen phosphorylase induced by phosphorylation. Nature 1988 2.16
14 The crystal structure of plasma gelsolin: implications for actin severing, capping, and nucleation. Cell 1997 2.10
15 A family of insertion mutations between codons 67 and 70 of human immunodeficiency virus type 1 reverse transcriptase confer multinucleoside analog resistance. Antimicrob Agents Chemother 1999 2.08
16 Structure of the TRAIL-DR5 complex reveals mechanisms conferring specificity in apoptotic initiation. Nat Struct Biol 1999 1.88
17 Tick histamine-binding proteins: isolation, cloning, and three-dimensional structure. Mol Cell 1999 1.88
18 Crystal structure of a heparin- and integrin-binding segment of human fibronectin. EMBO J 1999 1.84
19 The highly ordered double-stranded RNA genome of bluetongue virus revealed by crystallography. Cell 1999 1.84
20 Structural basis of superantigen action inferred from crystal structure of toxic-shock syndrome toxin-1. Nature 1994 1.67
21 Arginine-glycine-aspartic acid-specific binding by foot-and-mouth disease viruses to the purified integrin alpha(v)beta3 in vitro. J Virol 1997 1.65
22 Structural basis for the resilience of efavirenz (DMP-266) to drug resistance mutations in HIV-1 reverse transcriptase. Structure 2000 1.60
23 Catalysis in the crystal: synchrotron radiation studies with glycogen phosphorylase b. EMBO J 1987 1.60
24 Structure of HIV-2 reverse transcriptase at 2.35-A resolution and the mechanism of resistance to non-nucleoside inhibitors. Proc Natl Acad Sci U S A 2002 1.60
25 Crystal structure of an integrin-binding fragment of vascular cell adhesion molecule-1 at 1.8 A resolution. Nature 1995 1.55
26 Unique features in the structure of the complex between HIV-1 reverse transcriptase and the bis(heteroaryl)piperazine (BHAP) U-90152 explain resistance mutations for this nonnucleoside inhibitor. Proc Natl Acad Sci U S A 1997 1.55
27 Killer cell immunoglobulin receptors and T cell receptors bind peptide-major histocompatibility complex class I with distinct thermodynamic and kinetic properties. J Biol Chem 1999 1.50
28 High-throughput sample handling and data collection at synchrotrons: embedding the ESRF into the high-throughput gene-to-structure pipeline. Acta Crystallogr D Biol Crystallogr 2006 1.50
29 Crystal structure of the extracellular region of the human cell adhesion molecule CD2 at 2.5 A resolution. Structure 1994 1.44
30 Crystal structure of the extracellular region of human tissue factor. Nature 1994 1.43
31 Structural mechanisms of drug resistance for mutations at codons 181 and 188 in HIV-1 reverse transcriptase and the improved resilience of second generation non-nucleoside inhibitors. J Mol Biol 2001 1.42
32 Evidence for the role of His-142 of protein 1C in the acid-induced disassembly of foot-and-mouth disease virus capsids. J Gen Virol 1999 1.38
33 An altered position of the alpha 2 helix of MHC class I is revealed by the crystal structure of HLA-B*3501. Immunity 1996 1.38
34 Refined structure of baboon alpha-lactalbumin at 1.7 A resolution. Comparison with C-type lysozyme. J Mol Biol 1989 1.38
35 Design of MKC-442 (emivirine) analogues with improved activity against drug-resistant HIV mutants. J Med Chem 1999 1.36
36 Antagonist HIV-1 Gag peptides induce structural changes in HLA B8. J Exp Med 1996 1.36
37 Translocation portals for the substrates and products of a viral transcription complex: the bluetongue virus core. EMBO J 2001 1.35
38 The structure of a cypovirus and the functional organization of dsRNA viruses. Nat Struct Biol 1999 1.35
39 Signaling lymphocytic activation molecule (CDw150) is homophilic but self-associates with very low affinity. J Biol Chem 2000 1.34
40 The crystal structure and biological function of leukemia inhibitory factor: implications for receptor binding. Cell 1994 1.29
41 The human low affinity Fcgamma receptors IIa, IIb, and III bind IgG with fast kinetics and distinct thermodynamic properties. J Biol Chem 2001 1.28
42 Bound water structure and polymorphic amino acids act together to allow the binding of different peptides to MHC class I HLA-B53. Immunity 1996 1.27
43 Viral RNA modulates the acid sensitivity of foot-and-mouth disease virus capsids. J Virol 1995 1.27
44 Crystal structure of a berenil-dodecanucleotide complex: the role of water in sequence-specific ligand binding. EMBO J 1990 1.26
45 Structural features impose tight peptide binding specificity in the nonclassical MHC molecule HLA-E. Mol Cell 1998 1.25
46 Continuous and discontinuous changes in the unit cell of HIV-1 reverse transcriptase crystals on dehydration. Acta Crystallogr D Biol Crystallogr 1998 1.22
47 Expression of soluble recombinant glycoproteins with predefined glycosylation: application to the crystallization of the T-cell glycoprotein CD2. Protein Eng 1993 1.21
48 Classical and nonclassical class I major histocompatibility complex molecules exhibit subtle conformational differences that affect binding to CD8alphaalpha. J Biol Chem 2000 1.21
49 An atomic model of the outer layer of the bluetongue virus core derived from X-ray crystallography and electron cryomicroscopy. Structure 1997 1.21
50 Structure of the complex of an Fab fragment of a neutralizing antibody with foot-and-mouth disease virus: positioning of a highly mobile antigenic loop. EMBO J 1997 1.20
51 Structure of the brain-derived neurotrophic factor/neurotrophin 3 heterodimer. Biochemistry 1995 1.20
52 Crystal structure of human alpha-lactalbumin at 1.7 A resolution. J Mol Biol 1991 1.20
53 Determination of the affinity and kinetic constants for the interaction between the human virus echovirus 11 and its cellular receptor, CD55. J Biol Chem 1998 1.19
54 Crystal structure of the human p58 killer cell inhibitory receptor (KIR2DL3) specific for HLA-Cw3-related MHC class I. Structure 1999 1.17
55 Ligand binding by the immunoglobulin superfamily recognition molecule CD2 is glycosylation-independent. J Biol Chem 1995 1.16
56 Crystal structures of HIV-1 reverse transcriptase in complex with carboxanilide derivatives. Biochemistry 1998 1.16
57 Effects of N-butyldeoxynojirimycin and the Lec3.2.8.1 mutant phenotype on N-glycan processing in Chinese hamster ovary cells: application to glycoprotein crystallization. Protein Sci 1999 1.15
58 3'-Azido-3'-deoxythymidine drug resistance mutations in HIV-1 reverse transcriptase can induce long range conformational changes. Proc Natl Acad Sci U S A 1998 1.14
59 The atomic structure of Carnation Mottle Virus capsid protein. FEBS Lett 1994 1.11
60 Application of high-throughput technologies to a structural proteomics-type analysis of Bacillus anthracis. Acta Crystallogr D Biol Crystallogr 2006 1.11
61 Alpha-lactalbumin possesses a novel calcium binding loop. Nature 1986 1.11
62 Crystal structures of Zidovudine- or Lamivudine-resistant human immunodeficiency virus type 1 reverse transcriptases containing mutations at codons 41, 184, and 215. J Virol 2002 1.10
63 SPINE bioinformatics and data-management aspects of high-throughput structural biology. Acta Crystallogr D Biol Crystallogr 2006 1.08
64 Production and crystallization of MHC class I B allele single peptide complexes. FEBS Lett 1996 1.07
65 Nonstandard peptide binding revealed by crystal structures of HLA-B*5101 complexed with HIV immunodominant epitopes. J Immunol 2000 1.04
66 Substrate-cofactor interactions for glycogen phosphorylase b: a binding study in the crystal with heptenitol and heptulose 2-phosphate. Biochemistry 1984 1.04
67 The structures of the neurotrophin 4 homodimer and the brain-derived neurotrophic factor/neurotrophin 4 heterodimer reveal a common Trk-binding site. Protein Sci 1999 1.03
68 Phenylethylthiazolylthiourea (PETT) non-nucleoside inhibitors of HIV-1 and HIV-2 reverse transcriptases. Structural and biochemical analyses. J Biol Chem 2000 0.99
69 Crystallization and preliminary X-ray crystallographic studies on the bacteriophage phi6 RNA-dependent RNA polymerase. Acta Crystallogr D Biol Crystallogr 2000 0.99
70 Uridine(5')diphospho(1)-alpha-D-glucose. A binding study to glycogen phosphorylase b in the crystal. Eur J Biochem 1988 0.98
71 Production, crystallization, and preliminary X-ray analysis of the human MHC class Ib molecule HLA-E. Protein Sci 1998 0.98
72 Crystallization and functional analysis of a soluble deglycosylated form of the human costimulatory molecule B7-1. Acta Crystallogr D Biol Crystallogr 2001 0.97
73 Crystallization of the membrane-containing bacteriophage PRD1 in quartz capillaries by vapour diffusion. Acta Crystallogr D Biol Crystallogr 2003 0.97
74 Structure of pyruvate kinase and similarities with other enzymes: possible implications for protein taxonomy and evolution. Nature 1978 0.96
75 Virus crystallography. Mol Biotechnol 1999 0.96
76 Alpha-lactalbumin possesses a distinct zinc binding site. J Biol Chem 1993 0.95
77 The crystal structure of the catalytic domain of human urokinase-type plasminogen activator. Structure 1995 0.94
78 Kelp fly virus: a novel group of insect picorna-like viruses as defined by genome sequence analysis and a distinctive virion structure. J Virol 2005 0.94
79 Lipofectin increases the specific activity of cypovirus particles for cultured insect cells. J Virol Methods 1999 0.93
80 Binding of the second generation non-nucleoside inhibitor S-1153 to HIV-1 reverse transcriptase involves extensive main chain hydrogen bonding. J Biol Chem 2000 0.93
81 Crystallization and preliminary X-ray analysis of the core particle of bluetongue virus. Virology 1995 0.93
82 Application of the use of high-throughput technologies to the determination of protein structures of bacterial and viral pathogens. Acta Crystallogr D Biol Crystallogr 2006 0.93
83 Structures of orbivirus VP7: implications for the role of this protein in the viral life cycle. Structure 1997 0.92
84 Phosphorylase: control and activity. Philos Trans R Soc Lond B Biol Sci 1981 0.91
85 The structure of foot-and-mouth disease virus. Curr Top Microbiol Immunol 2005 0.91
86 Pyridoxal phosphate site in glycogen phosphorylase b: structure in native enzyme and in three derivatives with modified cofactors. Biochemistry 1987 0.90
87 Genomics and structure/function studies of Rhabdoviridae proteins involved in replication and transcription. Antiviral Res 2010 0.90
88 Recognition surfaces of MHC class I. Immunol Rev 1998 0.89
89 Crystal structure of the CD2-binding domain of CD58 (lymphocyte function-associated antigen 3) at 1.8-A resolution. Proc Natl Acad Sci U S A 1999 0.89
90 Expression cloning of an equine T-lymphocyte glycoprotein CD2 cDNA. Structure-based analysis of conserved sequence elements. Eur J Biochem 1994 0.88
91 Crystal structure of TNF. Immunol Ser 1992 0.88
92 Preliminary crystallographic study of bluetongue virus capsid protein, VP7. J Mol Biol 1992 0.88
93 On the derivation of dynamic information from diffraction data. Methods Enzymol 1985 0.87
94 The core of bluetongue virus binds double-stranded RNA. J Virol 2002 0.87
95 Comparison of AMP and NADH binding to glycogen phosphorylase b. J Mol Biol 1983 0.87
96 Macromolecular assemblies: greater than their parts. Curr Opin Struct Biol 2001 0.86
97 Catalysis in enzyme crystals. Trends Biochem Sci 1988 0.86
98 Specific interactions between human integrin alpha v beta 3 and chimeric hepatitis B virus core particles bearing the receptor-binding epitope of foot-and-mouth disease virus. Virology 1997 0.85
99 Crystallization and preliminary X-ray diffraction characterisation of both a native and selenomethionyl VLA-4 binding fragment of VCAM-1. J Mol Biol 1994 0.85
100 Preliminary crystallographic data for NAD(P)H quinone reductase isolated from the Walker 256 rat carcinoma cell line. J Mol Biol 1989 0.84
101 2-Amino-6-arylsulfonylbenzonitriles as non-nucleoside reverse transcriptase inhibitors of HIV-1. J Med Chem 2001 0.84
102 Time-resolved structural studies on catalysis in the crystal with glycogen phosphorylase b. Biochem Soc Trans 1986 0.83
103 Models which explain the inhibition of reverse transcriptase by HIV-1-specific (thio)carboxanilide derivatives. Biochem Biophys Res Commun 1997 0.83
104 The N-glycosidase mechanism of ribosome-inactivating proteins implied by crystal structures of alpha-momorcharin. Structure 1994 0.82
105 The structure of tumour necrosis factor--implications for biological function. J Cell Sci Suppl 1990 0.82
106 Allosteric interactions of glycogen phosphorylase b. A crystallographic study of glucose 6-phosphate and inorganic phosphate binding to di-imidate-cross-linked phosphorylase b. Biochem J 1984 0.82
107 The crystal and molecular structure of an osmium bispyridine adduct of thymine. Biochim Biophys Acta 1976 0.82
108 Complementing crystallography: the role of cryo-electron microscopy in structural biology. Acta Crystallogr D Biol Crystallogr 1999 0.81
109 Crystallographic analysis of the binding modes of thiazoloisoindolinone non-nucleoside inhibitors to HIV-1 reverse transcriptase and comparison with modeling studies. J Med Chem 1999 0.81
110 The structure and function of pyruvate kinase. Biochem Soc Trans 1981 0.81
111 Purification, crystallization and preliminary X-ray diffraction studies of alpha-toxin of Clostridium perfringens. J Mol Biol 1994 0.81
112 From lysozyme to alpha-lactalbumin: protein engineering and evolution. Biochem Soc Trans 1987 0.81
113 Methodology employed for the structure determination of tumour necrosis factor, a case of high non-crystallographic symmetry. Acta Crystallogr A 1991 0.81
114 The VIZIER project: preparedness against pathogenic RNA viruses. Antiviral Res 2007 0.79
115 Cutting complexity down to size. Nature 1997 0.78
116 Preliminary crystallographic study of D(-)-mandelate dehydrogenase from Rhodotorula graminis. J Mol Biol 1993 0.78
117 Large unit cells and cellular mechanics. Nat Struct Biol 1998 0.77
118 Crystallization and preliminary X-ray analysis of human rhinovirus serotype 2 (HRV2). Acta Crystallogr D Biol Crystallogr 1999 0.77
119 Models of the three-dimensional structures of echidna, horse, and pigeon lysozymes: calcium-binding lysozymes and their relationship with alpha-lactalbumins. J Protein Chem 1994 0.76
120 A critical evaluation of the predicted and X-ray structures of alpha-lactalbumin. J Protein Chem 1990 0.76
121 Crystals of the neurotrophins. Protein Sci 1996 0.75
122 Crystallographic analysis of the three-dimensional structure of baboon alpha-lactalbumin at low resolution. Homology with lysozyme. Biochem J 1987 0.75
123 Crystallization and preliminary diffraction studies of the extracellular region of human p58 killer cell inhibitory receptor (KIR2). Acta Crystallogr D Biol Crystallogr 1998 0.75
124 The three-dimensional structure of tumour necrosis factor. Prog Clin Biol Res 1990 0.75
125 Allosteric inhibitors against HIV-1 reverse transcriptase: design and synthesis of MKC-442 analogues having an omega-functionalized acyclic structure. Antivir Chem Chemother 1998 0.75
126 The binding of beta-glycerophosphate to glycogen phosphorylase b in the crystal. Arch Biochem Biophys 1989 0.75
127 Phosphate-recognition sites in catalysis and control of glycogen phosphorylase b. Biochem Soc Trans 1987 0.75
128 The role of pyridoxal phosphate in glycogen phosphorylase b; structure, environment and relationship to catalytic mechanism. Prog Clin Biol Res 1984 0.75
129 Structure of cat muscle pyruvate kinase at 0.26 nm resolution. Biochem Soc Trans 1977 0.75
130 The crystal structure of murine leukemia inhibitory factor. Ann N Y Acad Sci 1995 0.75
131 Preliminary crystallographic data for Pneumocystis carinii dihydrofolate reductase. J Mol Biol 1993 0.75