Published in Am J Physiol on June 01, 1999
Phosphoenolpyruvate carboxykinase is necessary for the integration of hepatic energy metabolism. Mol Cell Biol (2000) 2.42
Deletion of the mammalian INDY homolog mimics aspects of dietary restriction and protects against adiposity and insulin resistance in mice. Cell Metab (2011) 1.98
Resistance to diet-induced obesity in mice with synthetic glyoxylate shunt. Cell Metab (2009) 1.56
Malonyl coenzyme A and the regulation of functional carnitine palmitoyltransferase-1 activity and fat oxidation in human skeletal muscle. J Clin Invest (2002) 1.31
Sites of superoxide and hydrogen peroxide production by muscle mitochondria assessed ex vivo under conditions mimicking rest and exercise. J Biol Chem (2014) 1.12
A genetically encoded FRET lactate sensor and its use to detect the Warburg effect in single cancer cells. PLoS One (2013) 1.11
The malonyl-CoA-long-chain acyl-CoA axis in the maintenance of mammalian cell function. Biochem J (1999) 1.07
Peroxisomal-proliferator-activated receptor alpha activates transcription of the rat hepatic malonyl-CoA decarboxylase gene: a key regulation of malonyl-CoA level. Biochem J (2004) 1.03
Imaging mitochondrial flux in single cells with a FRET sensor for pyruvate. PLoS One (2014) 0.94
Long-chain fatty acid combustion rate is associated with unique metabolite profiles in skeletal muscle mitochondria. PLoS One (2010) 0.87
Knockdown of Indy/CeNac2 extends Caenorhabditis elegans life span by inducing AMPK/aak-2. Aging (Albany NY) (2015) 0.84
The genome of black cottonwood, Populus trichocarpa (Torr. & Gray). Science (2006) 21.03
Feature extraction and normalization algorithms for high-density oligonucleotide gene expression array data. J Cell Biochem Suppl (2001) 8.50
Free fatty acid-induced insulin resistance is associated with activation of protein kinase C theta and alterations in the insulin signaling cascade. Diabetes (1999) 7.14
A method of uniform stratification of risk for evaluating the results of surgery in acquired adult heart disease. Circulation (1989) 6.28
Causes and outcomes of the acute chest syndrome in sickle cell disease. National Acute Chest Syndrome Study Group. N Engl J Med (2000) 6.07
Cognitive behaviour therapy for the chronic fatigue syndrome: a randomized controlled trial. BMJ (1996) 5.34
The spc ribosomal protein operon of Escherichia coli: sequence and cotranscription of the ribosomal protein genes and a protein export gene. Nucleic Acids Res (1983) 4.46
Malonyl-CoA, fuel sensing, and insulin resistance. Am J Physiol (1999) 3.48
Influence of dietary fat composition on development of insulin resistance in rats. Relationship to muscle triglyceride and omega-3 fatty acids in muscle phospholipid. Diabetes (1991) 3.14
Feedback regulation of ribosomal protein gene expression in Escherichia coli: structural homology of ribosomal RNA and ribosomal protein MRNA. Proc Natl Acad Sci U S A (1980) 3.11
The "metabolically-obese," normal-weight individual. Am J Clin Nutr (1981) 2.71
Aleurain: a barley thiol protease closely related to mammalian cathepsin H. Proc Natl Acad Sci U S A (1985) 2.67
Evaluation of the isolated perfused rat hindquarter for the study of muscle metabolism. Biochem J (1971) 2.66
Electron microscopic and biochemical study of lipoprotein synthesis in the isolated perfused rat liver. J Lipid Res (1967) 2.58
Contraction-induced changes in acetyl-CoA carboxylase and 5'-AMP-activated kinase in skeletal muscle. J Biol Chem (1997) 2.54
Muscle glucose metabolism following exercise in the rat: increased sensitivity to insulin. J Clin Invest (1982) 2.41
Dose-response curves for in vivo insulin sensitivity in individual tissues in rats. Am J Physiol (1985) 2.39
Alterations in the expression and cellular localization of protein kinase C isozymes epsilon and theta are associated with insulin resistance in skeletal muscle of the high-fat-fed rat. Diabetes (1997) 2.37
Heterogeneity of insulin action in individual muscles in vivo: euglycemic clamp studies in rats. Am J Physiol (1985) 2.34
Oligomerization activates c-Raf-1 through a Ras-dependent mechanism. Nature (1996) 2.29
Fish oil prevents insulin resistance induced by high-fat feeding in rats. Science (1987) 2.26
Nano-network electronic conduction in iron and nickel olivine phosphates. Nat Mater (2004) 2.14
The phosphatidylinositol 3-kinase serine kinase phosphorylates IRS-1. Stimulation by insulin and inhibition by Wortmannin. J Biol Chem (1994) 2.09
Fat feeding causes widespread in vivo insulin resistance, decreased energy expenditure, and obesity in rats. Am J Physiol (1986) 2.01
Mechanisms of liver and muscle insulin resistance induced by chronic high-fat feeding. Diabetes (1997) 1.95
Mechanism of electrical enhancement of efficacy of antibiotics in killing biofilm bacteria. Antimicrob Agents Chemother (1994) 1.95
Peroxisome proliferator-activated receptor (PPAR)-alpha activation lowers muscle lipids and improves insulin sensitivity in high fat-fed rats: comparison with PPAR-gamma activation. Diabetes (2001) 1.93
Glucose metabolism in perfused skeletal muscle. Effects of starvation, diabetes, fatty acids, acetoacetate, insulin and exercise on glucose uptake and disposition. Biochem J (1976) 1.90
The formation of glutamine and alanine in skeletal muscle. J Biol Chem (1974) 1.90
Prevention and control of bacterial infections associated with medical devices. ASAIO J (1993) 1.88
Insulin-stimulated phosphatidylinositol 3-kinase. Association with a 185-kDa tyrosine-phosphorylated protein (IRS-1) and localization in a low density membrane vesicle. J Biol Chem (1993) 1.88
Ras activation of the Raf kinase: tyrosine kinase recruitment of the MAP kinase cascade. Recent Prog Horm Res (2001) 1.87
A plasmid cloning vector for the direct selection of strains carrying recombinant plasmids. Gene (1981) 1.84
Carrier solutions for low-level intravenous insulin infusion. Br Med J (1975) 1.83
Beta-cell adaptation and decompensation during the progression of diabetes. Diabetes (2001) 1.81
Feedback regulation of ribosomal protein gene expression in Escherichia coli. Proc Natl Acad Sci U S A (1980) 1.79
Regulation of glucose and ketone-body metabolism in brain of anaesthetized rats. Biochem J (1974) 1.78
Improving mental health through parenting programmes: block randomised controlled trial. Arch Dis Child (2002) 1.78
The unreliability of clinical measures of muscle tone: implications for stroke therapy. Age Ageing (2000) 1.78
SH2- and SH3-mediated interactions between focal adhesion kinase and Src. J Biol Chem (1998) 1.77
Overview of the epidemiology, microbiology, and pathogenesis of Leptospira spp. in humans. Microbes Infect (2000) 1.76
Atrophy progression in semantic dementia with asymmetric temporal involvement: a tensor-based morphometry study. Neurobiol Aging (2007) 1.74
Glucose metabolism in perfused skeletal muscle. Interaction of insulin and exercise on glucose uptake. Biochem J (1975) 1.71
The role of intramuscular lipid in insulin resistance. Acta Physiol Scand (2003) 1.70
Recombination in the ompA gene but not the omcB gene of Chlamydia contributes to serovar-specific differences in tissue tropism, immune surveillance, and persistence of the organism. J Bacteriol (2001) 1.70
Effect of acetoacetate on glucose metabolism in the soleus and extensor digitorum longus muscles of the rat. Biochem J (1977) 1.69
Evidence that lysosomes are not involved in the degradation of myofibrillar proteins in rat skeletal muscle. Biochem J (1986) 1.66
Glucose regulation of hepatic gluconeogenesis. Am J Physiol (1968) 1.64
E. coli ribosomal protein L10 inhibits translation of L10 and L7/L12 mRNAs by acting at a single site. Nature (1981) 1.64
Role of free fatty acids in glucose homeostasis. Arch Intern Med (1969) 1.61
Muscle amino acid metabolism and gluconeogenesis. Annu Rev Med (1975) 1.61
Glucose metabolism in rat skeletal muscle at rest. Effect of starvation, diabetes, ketone bodies and free fatty acids. Diabetes (1974) 1.61
Fructose-induced in vivo insulin resistance and elevated plasma triglyceride levels in rats. Am J Clin Nutr (1989) 1.60
Five-hour fatty acid elevation increases muscle lipids and impairs glycogen synthesis in the rat. Metabolism (1998) 1.57
Acetoacetate as a fuel for perfused rat skeletal muscle. Biochem J (1971) 1.54
In vivo insulin sensitivity in the rat determined by euglycemic clamp. Am J Physiol (1983) 1.49
Insulin sensitivity indices: a proposal of cut-off points for simple identification of insulin-resistant subjects. Exp Clin Endocrinol Diabetes (2006) 1.49
Long-chain acyl-CoA esters as indicators of lipid metabolism and insulin sensitivity in rat and human muscle. Am J Physiol Endocrinol Metab (2000) 1.48
Distinct patterns of tissue-specific lipid accumulation during the induction of insulin resistance in mice by high-fat feeding. Diabetologia (2013) 1.48
Escherichia coli ribosomal protein S8 feedback regulates part of spc operon. Nature (1981) 1.47
Successful treatment of herpes labialis with topical acyclovir. Br Med J (Clin Res Ed) (1983) 1.45
New JCAH president faces problems and opportunities. Hospitals (1977) 1.44
Starvation in the rat. II. Effect of age and obesity on protein sparing and fuel metabolism. Am J Physiol (1980) 1.43
The psychosocial impact of HIV infection in gay men. A controlled investigation and factors associated with psychiatric morbidity. Br J Psychiatry (1992) 1.43
Phosphatidylinositol-3-kinase in isolated rat adipocytes. Activation by insulin and subcellular distribution. J Biol Chem (1992) 1.43
A new antidiabetic agent, BRL 49653, reduces lipid availability and improves insulin action and glucoregulation in the rat. Diabetes (1994) 1.40
Muscle glycogenolysis during exercise: dual control by epinephrine and contractions. Am J Physiol (1982) 1.40
Evidence for a major gene affecting the transition from normoglycaemia to hyperglycaemia in Psammomys obesus. Heredity (Edinb) (2005) 1.40
Leptinomimetic effects of the AMP kinase activator AICAR in leptin-resistant rats: prevention of diabetes and ectopic lipid deposition. Diabetologia (2004) 1.40
Insulin binding and sensitivity in rat skeletal muscle: effect of starvation. Am J Physiol (1981) 1.39
AMPK as a metabolic switch in rat muscle, liver and adipose tissue after exercise. Acta Physiol Scand (2003) 1.36
Diabetes as an atherogenic factor. Prog Cardiovasc Dis (1984) 1.35
Diabetes and exercise. Am J Med (1981) 1.33
An electron microscopic study of lipoprotein production and release by the isolated perfused rat liver. Proc Soc Exp Biol Med (1966) 1.33
The WHO patient safety curriculum guide for medical schools. Qual Saf Health Care (2010) 1.33
Structure of the Tie2 RTK domain: self-inhibition by the nucleotide binding loop, activation loop, and C-terminal tail. Structure (2000) 1.32
A large multi-centre European study validates high-sensitivity C-reactive protein (hsCRP) as a clinical biomarker for the diagnosis of diabetes subtypes. Diabetologia (2011) 1.31
Activation of malonyl-CoA decarboxylase in rat skeletal muscle by contraction and the AMP-activated protein kinase activator 5-aminoimidazole-4-carboxamide-1-beta -D-ribofuranoside. J Biol Chem (2000) 1.31
In vivo glucose metabolism in individual tissues of the rat. Interaction between epinephrine and insulin. J Biol Chem (1986) 1.30
Starvation in the rat. I. Effect of age and obesity on organ weights, RNA, DNA, and protein. Am J Physiol (1980) 1.29
High prevalence of prediabetes and diabetes in a population exposed to high levels of an organochlorine cocktail. Diabetologia (2010) 1.28
Insulin therapy in obese, non-insulin-dependent diabetes induces improvements in insulin action and secretion that are maintained for two weeks after insulin withdrawal. Diabetes (1984) 1.27
The story of Bacillus thuringiensis var. israelensis (B.t.i.). J Am Mosq Control Assoc (1985) 1.26
Adaptation to prolonged starvation in the rat: curtailment of skeletal muscle proteolysis. Am J Physiol (1981) 1.25
Synthesis and properties of photocross-linked poly(propylene fumarate) scaffolds. J Biomater Sci Polym Ed (2001) 1.24
Malonyl-CoA and AMP-activated protein kinase (AMPK): possible links between insulin resistance in muscle and early endothelial cell damage in diabetes. Biochem Soc Trans (2003) 1.24
Enhanced muscle glucose metabolism after exercise: modulation by local factors. Am J Physiol (1984) 1.24
Testing antimicrobial susceptibilities of adherent bacteria by a method that incorporates guidelines of the National Committee for Clinical Laboratory Standards. J Clin Microbiol (1994) 1.24
Outpatient operations. II. As the G.P. sees it. Br Med J (1969) 1.23
Physiological importance of deficiency in early prandial insulin secretion in non-insulin-dependent diabetes. Diabetes (1988) 1.23
Comparative organization of nitrogen fixation-specific genes from Azotobacter vinelandii and Klebsiella pneumoniae: DNA sequence of the nifUSV genes. J Bacteriol (1987) 1.23
Biogenesis of molybdenum cofactors. Crit Rev Microbiol (1990) 1.21
Glucose and amino acid metabolism in perfused skeletal muscle. Effect of dichloroacetate. Diabetes (1978) 1.21
Paraneoplastic pemphigus: an association with fludarabine? Br J Dermatol (2001) 1.21