D R Laybutt

Author PubWeight™ 11.73‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Beta-cell adaptation and decompensation during the progression of diabetes. Diabetes 2001 1.81
2 A new antidiabetic agent, BRL 49653, reduces lipid availability and improves insulin action and glucoregulation in the rat. Diabetes 1994 1.40
3 High glucose stimulates early response gene c-Myc expression in rat pancreatic beta cells. J Biol Chem 2001 1.11
4 Reduced endoplasmic reticulum (ER)-to-Golgi protein trafficking contributes to ER stress in lipotoxic mouse beta cells by promoting protein overload. Diabetologia 2009 1.11
5 The influence of genetic background on the induction of oxidative stress and impaired insulin secretion in mouse islets. Diabetologia 2006 1.10
6 Cytosolic citrate and malonyl-CoA regulation in rat muscle in vivo. Am J Physiol 1999 0.97
7 Differential regulation of adaptive and apoptotic unfolded protein response signalling by cytokine-induced nitric oxide production in mouse pancreatic beta cells. Diabetologia 2011 0.92
8 Pharmacological reduction of NEFA restores the efficacy of incretin-based therapies through GLP-1 receptor signalling in the beta cell in mouse models of diabetes. Diabetologia 2012 0.90
9 Deletion of protein kinase Cδ in mice modulates stability of inflammatory genes and protects against cytokine-stimulated beta cell death in vitro and in vivo. Diabetologia 2010 0.86
10 Cross-talk between the unfolded protein response and nuclear factor-κB signalling pathways regulates cytokine-mediated beta cell death in MIN6 cells and isolated mouse islets. Diabetologia 2012 0.82
11 Malonyl CoA as a metabolic switch and a regulator of insulin sensitivity. Adv Exp Med Biol 1998 0.77