Enhanced expression of CD80 (B7-1), CD86 (B7-2), and CD40 and their ligands CD28 and CD154 in fulminant hepatic failure.

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Published in Am J Pathol on June 01, 1999

Authors

L Leifeld1, C Trautwein, F L Dumoulin, M P Manns, T Sauerbruch, U Spengler

Author Affiliations

1: Department of Internal Medicine, University of Bonn, Germany.

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Surgical intervention following fragmentation of gallstones by extracorporeal shock waves. World J Surg (1989) 1.42

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Serum bile acids: physiology and clinical relevance. Eur J Gastroenterol Hepatol (1995) 1.41

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