R B Darnell

Author PubWeight™ 76.85‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Microarray identification of FMRP-associated brain mRNAs and altered mRNA translational profiles in fragile X syndrome. Cell 2001 8.04
2 Fragile X mental retardation protein targets G quartet mRNAs important for neuronal function. Cell 2001 6.50
3 Nova-1 regulates neuron-specific alternative splicing and is essential for neuronal viability. Neuron 2000 4.24
4 Detection and treatment of activated T cells in the cerebrospinal fluid of patients with paraneoplastic cerebellar degeneration. Ann Neurol 2000 3.61
5 Sequence-specific RNA binding by a Nova KH domain: implications for paraneoplastic disease and the fragile X syndrome. Cell 2000 3.59
6 A brain-enriched polypyrimidine tract-binding protein antagonizes the ability of Nova to regulate neuron-specific alternative splicing. Proc Natl Acad Sci U S A 2000 3.11
7 Dendritic cell maturation is required for the cross-tolerization of CD8+ T cells. Nat Immunol 2001 2.98
8 Nova, the paraneoplastic Ri antigen, is homologous to an RNA-binding protein and is specifically expressed in the developing motor system. Neuron 1993 2.81
9 A hierarchy of Hu RNA binding proteins in developing and adult neurons. J Neurosci 1997 2.76
10 A novel adaptor-related protein complex. J Cell Biol 1996 2.69
11 The neuronal RNA binding protein Nova-1 recognizes specific RNA targets in vitro and in vivo. Mol Cell Biol 1997 2.69
12 Involvement of the TRAP220 component of the TRAP/SMCC coactivator complex in embryonic development and thyroid hormone action. Mol Cell 2000 2.39
13 The neuronal RNA-binding protein Nova-2 is implicated as the autoantigen targeted in POMA patients with dementia. Proc Natl Acad Sci U S A 1998 2.22
14 Tumor-specific killer cells in paraneoplastic cerebellar degeneration. Nat Med 1998 2.11
15 The onconeural antigen Nova-1 is a neuron-specific RNA-binding protein, the activity of which is inhibited by paraneoplastic antibodies. J Neurosci 1996 2.03
16 FMRP RNA targets: identification and validation. Genes Brain Behav 2005 1.97
17 Mammalian ELAV-like neuronal RNA-binding proteins HuB and HuC promote neuronal development in both the central and the peripheral nervous systems. Proc Natl Acad Sci U S A 1999 1.93
18 The tetranucleotide UCAY directs the specific recognition of RNA by the Nova K-homology 3 domain. Proc Natl Acad Sci U S A 2000 1.92
19 Beta-NAP, a cerebellar degeneration antigen, is a neuron-specific vesicle coat protein. Cell 1995 1.81
20 ATM binds to beta-adaptin in cytoplasmic vesicles. Proc Natl Acad Sci U S A 1998 1.63
21 Crystal structures of Nova-1 and Nova-2 K-homology RNA-binding domains. Structure 1999 1.59
22 The splice of life: alternative splicing and neurological disease. Nat Rev Neurosci 2001 1.57
23 Differential expression of the human gonadotropin alpha gene in ectopic and eutopic cells. Mol Cell Biol 1985 1.53
24 cdr2-specific CTLs are detected in the blood of all patients with paraneoplastic cerebellar degeneration analyzed. Ann Neurol 2000 1.42
25 The cytoplasmic Purkinje onconeural antigen cdr2 down-regulates c-Myc function: implications for neuronal and tumor cell survival. Genes Dev 1999 1.32
26 Paraneoplastic neurologic disease antigens: RNA-binding proteins and signaling proteins in neuronal degeneration. Annu Rev Neurosci 2001 1.29
27 Cdr2, a target antigen of naturally occuring human tumor immunity, is widely expressed in gynecological tumors. Cancer Res 2000 1.11
28 A post-transcriptional regulatory mechanism restricts expression of the paraneoplastic cerebellar degeneration antigen cdr2 to immune privileged tissues. J Neurosci 1997 0.99
29 Independent regulation by sodium butyrate of gonadotropin alpha gene expression and cell cycle progression in HeLa cells. Mol Cell Biol 1984 0.98
30 The neuronal nuclear antigen recognized by the human anti-Ri autoantibody is expressed in central but not peripheral nervous system neurons. Neurosci Lett 1993 0.94
31 Mouse chromosomal locations of nine genes encoding homologs of human paraneoplastic neurologic disorder antigens. Genomics 1997 0.89
32 The importance of defining the paraneoplastic neurologic disorders. N Engl J Med 1999 0.86
33 Effective antigen cross-presentation by prostate cancer patients' dendritic cells: implications for prostate cancer immunotherapy. Prostate Cancer Prostatic Dis 2004 0.84
34 Neuronal signaling through alternative splicing: some exons CaRRE. Sci STKE 2001 0.83
35 Structure and expression of human placental hormone genes. Adv Exp Med Biol 1986 0.78