PubRank

G Jansen

Author PubWeight™ 101.80‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Myotonic dystrophy mutation: an unstable CTG repeat in the 3' untranslated region of the gene. Science 1992 9.32
2 Cloning of the essential myotonic dystrophy region and mapping of the putative defect. Nature 1992 4.45
3 Detection of an unstable fragment of DNA specific to individuals with myotonic dystrophy. Nature 1992 4.44
4 Functional analysis of 150 deletion mutants in Saccharomyces cerevisiae by a systematic approach. Mol Gen Genet 1999 2.26
5 Induction of thymidylate synthase as a 5-fluorouracil resistance mechanism. Biochim Biophys Acta 2002 1.98
6 Antifolate resistance mediated by the multidrug resistance proteins MRP1 and MRP2. Cancer Res 1999 1.72
7 MRP3, an organic anion transporter able to transport anti-cancer drugs. Proc Natl Acad Sci U S A 1999 1.59
8 Structure and genomic sequence of the myotonic dystrophy (DM kinase) gene. Hum Mol Genet 1993 1.44
9 Thymidylate synthase level as the main predictive parameter for sensitivity to 5-fluorouracil, but not for folate-based thymidylate synthase inhibitors, in 13 nonselected colon cancer cell lines. Clin Cancer Res 1999 1.38
10 Endocytosis of GPI-linked membrane folate receptor-alpha. J Cell Biol 1996 1.31
11 Capillary gas chromatographic profiling of urinary, plasma and erythrocyte sugars and polyols as their trimethylsilyl derivatives, preceded by a simple and rapid prepurification method. Clin Chim Acta 1986 1.31
12 Density-functional theory-symmetry-adapted intermolecular perturbation theory with density fitting: a new efficient method to study intermolecular interaction energies. J Chem Phys 2005 1.30
13 Impaired bortezomib binding to mutant β5 subunit of the proteasome is the underlying basis for bortezomib resistance in leukemia cells. Leukemia 2011 1.29
14 Influence of sex of the transmitting parent as well as of parental allele size on the CTG expansion in myotonic dystrophy (DM). Am J Hum Genet 1993 1.28
15 Role of folylpolyglutamate synthetase and folylpolyglutamate hydrolase in methotrexate accumulation and polyglutamylation in childhood leukemia. Blood 1999 1.20
16 Brief report: reverse mutation in myotonic dystrophy. N Engl J Med 1993 1.19
17 Relationship between allergic manifestations and Toxocara seropositivity: a cross-sectional study among elementary school children. Eur Respir J 1997 1.17
18 Modulation of both endogenous folates and thymidine enhance the therapeutic efficacy of thymidylate synthase inhibitors. Cancer Res 2001 1.14
19 Ste50p is involved in regulating filamentous growth in the yeast Saccharomyces cerevisiae and associates with Ste11p. Mol Gen Genet 1998 1.14
20 Development of sulfasalazine resistance in human T cells induces expression of the multidrug resistance transporter ABCG2 (BCRP) and augmented production of TNFalpha. Ann Rheum Dis 2004 1.13
21 Ste50p sustains mating pheromone-induced signal transduction in the yeast Saccharomyces cerevisiae. Mol Microbiol 1996 1.11
22 Bortezomib and TRAIL: a perfect match for apoptotic elimination of tumour cells? Crit Rev Oncol Hematol 2012 1.08
23 Constitutive and regulated modes of splicing produce six major myotonic dystrophy protein kinase (DMPK) isoforms with distinct properties. Hum Mol Genet 2000 1.08
24 mRNA expression levels of methotrexate resistance-related proteins in childhood leukemia as determined by a standardized competitive template-based RT-PCR method. Leukemia 2000 1.05
25 Presymptomatic diagnosis of myotonic dystrophy. J Med Genet 1992 1.02
26 Cellular pharmacology and in vivo activity of a new anticancer agent, ZD9331: a water-soluble, nonpolyglutamatable, quinazoline-based inhibitor of thymidylate synthase. Clin Cancer Res 1997 1.00
27 Acquired resistance of human T cells to sulfasalazine: stability of the resistant phenotype and sensitivity to non-related DMARDs. Ann Rheum Dis 2004 0.97
28 Effect of twelve antimicrobial drugs on the colonization resistance of the digestive tract of mice and on endogenous potentially pathogenic bacteria. J Hyg (Lond) 1982 0.97
29 Folate depletion increases sensitivity of solid tumor cell lines to 5-fluorouracil and antifolates. Int J Cancer 2000 0.96
30 Short communication: imputing genotypes using PedImpute fast algorithm combining pedigree and population information. J Dairy Sci 2013 0.96
31 Enhanced expression of fractalkine in HIV-1 associated dementia. J Neuroimmunol 2001 0.95
32 Synthesis and biological evaluation of a fluorescent analogue of folic acid. Biochemistry 1991 0.95
33 Drug transporters: recent advances concerning BCRP and tyrosine kinase inhibitors. Br J Cancer 2008 0.95
34 The proteasome inhibitor bortezomib inhibits the release of NFkappaB-inducible cytokines and induces apoptosis of activated T cells from rheumatoid arthritis patients. Clin Exp Rheumatol 2009 0.94
35 Membrane transport of natural folates and antifolate compounds in murine L1210 leukemia cells: role of carrier- and receptor-mediated transport systems. Cancer Res 1991 0.92
36 Myotonic dystrophy kinase is a component of neuromuscular junctions. Hum Mol Genet 1993 0.91
37 Impact of cellular folate status and epidermal growth factor receptor expression on BCRP/ABCG2-mediated resistance to gefitinib and erlotinib. Br J Cancer 2009 0.91
38 Influence of the prion protein and the apolipoprotein E genotype on the Creutzfeldt-Jakob Disease phenotype. Neurosci Lett 2001 0.89
39 Neurocutaneous melanosis with hydrocephalus, intraspinal arachnoid collections and syringomyelia: case report and literature review. Pediatr Radiol 2000 0.87
40 Characteristics of hexokinase, pyruvate kinase, and glucose-6-phosphate dehydrogenase during adult and neonatal reticulocyte maturation. Am J Hematol 1985 0.86
41 Functional activity of the reduced folate carrier in KB, MA104, and IGROV-I cells expressing folate-binding protein. Cancer Res 1995 0.86
42 Requirement of the Caenorhabditis elegans RapGEF pxf-1 and rap-1 for epithelial integrity. Mol Biol Cell 2004 0.86
43 Physical mapping and cloning of the proximal segment of the myotonic dystrophy gene region. Genomics 1992 0.85
44 Multidrug resistance proteins and folate supplementation: therapeutic implications for antifolates and other classes of drugs in cancer treatment. Cancer Chemother Pharmacol 2005 0.85
45 Differences in the induction of DNA damage, cell cycle arrest, and cell death by 5-fluorouracil and antifolates. Oncol Res 2000 0.84
46 Importance of pharmacodynamics in the in vitro antiproliferative activity of the antifolates methotrexate and 10-ethyl-10-deazaaminopterin against human head and neck squamous cell carcinoma. Biochem Pharmacol 1993 0.84
47 Determinants of activity of the antifolate thymidylate synthase inhibitors Tomudex (ZD1694) and GW1843U89 against mono- and multilayered colon cancer cell lines under folate-restricted conditions. Cancer Res 1999 0.84
48 Identification of a reduced folate/methotrexate carrier in human KB-cells expressing high levels of membrane associated folate binding protein. Adv Exp Med Biol 1993 0.83
49 Clustering of mutations in the first transmembrane domain of the human reduced folate carrier in GW1843U89-resistant leukemia cells with impaired antifolate transport and augmented folate uptake. J Biol Chem 2000 0.83
50 Cross-resistance to antifolates in multidrug resistant cell lines with P-glycoprotein or multidrug resistance protein expression. Biochem Pharmacol 1997 0.83
51 Comparison of phase-contrast MR imaging and endovascular sonography for intracranial blood flow velocity measurements. AJNR Am J Neuroradiol 2012 0.83
52 DNA damage leads to progressive replicative decline but extends the life span of long-lived mutant animals. Cell Death Differ 2013 0.83
53 Differential methotrexate resistance in childhood T- versus common/preB-acute lymphoblastic leukemia can be measured by an in situ thymidylate synthase inhibition assay, but not by the MTT assay. Blood 1999 0.83
54 Gas-chromatographic determination of cholesterol sulfate in plasma and erythrocytes, for the diagnosis of recessive X-linked ichthyosis. Clin Chem 1983 0.83
55 Profiling of plasma cholesterol ester and triglyceride fatty acids as their methyl esters by capillary gas chromatography, preceded by a rapid aminopropyl-silica column chromatographic separation of lipid classes. J Chromatogr 1988 0.82
56 Pressure-induced skin lesions in pigs: reperfusion injury and the effects of vitamin E. J Wound Care 2000 0.82
57 Fat absorption in neonates: comparison of long-chain-fatty-acid and triglyceride compositions of formula, feces, and blood. Am J Clin Nutr 1991 0.82
58 Classification of ex vivo methotrexate resistance in acute lymphoblastic and myeloid leukaemia. Br J Haematol 2000 0.82
59 Metabolic aspects of peroxisomal disorders. Ann N Y Acad Sci 1996 0.82
60 Separation and characterization of hexokinase I subtypes from human erythrocytes. Biochim Biophys Acta 1981 0.82
61 Characterization of a human alternatively spliced truncated reduced folate carrier increasing folate accumulation in parental leukemia cells. Eur J Biochem 2000 0.81
62 Molecular events in the membrane transport of methotrexate in human CCRF-CEM leukemia cell lines. Adv Enzyme Regul 1992 0.81
63 Isochromosome 12p-positive pineal germ cell tumor. Cancer Res 1994 0.81
64 Ex vivo activity of methotrexate versus novel antifolate inhibitors of dihydrofolate reductase and thymidylate synthase against childhood leukemia cells. Clin Cancer Res 1998 0.80
65 Glycolytic enzymes of an erythroleukemic cell line, K562, before and after hemoglobin induction. Exp Hematol 1983 0.80
66 A comparison of the efficacy of levobupivacaine 0.125%, ropivacaine 0.125% and ropivacaine 0.2%, all combined with sufentanil 0.5 microg/mL, in patient-controlled epidural analgesia after hysterectomy under combined epidural and general anesthesia. Acta Anaesthesiol Belg 2012 0.79
67 Functional aspects of membrane folate receptors in human breast cancer cells with transport-related resistance to methotrexate. Cancer Chemother Pharmacol 1996 0.79
68 Re: Folylpolyglutamyl synthetase gene transfer and glioma antifolate sensitivity in culture and in vivo. J Natl Cancer Inst 1999 0.79
69 A possible role for methotrexate in the treatment of childhood acute myeloid leukaemia, in particular for acute monocytic leukaemia. Eur J Cancer 2001 0.79
70 Changes in activities and isozyme patterns of glycolytic enzymes during erythroid differentiation in vitro. Blood 1984 0.79
71 Variant GPI structure in relation to membrane-associated functions of a murine folate receptor. Biochemistry 1996 0.79
72 Methotrexate resistance in relapsed childhood acute lymphoblastic leukaemia. Br J Haematol 2000 0.78
73 Analysis of the DNA sequence of a 34,038 bp region on the left arm of yeast chromosome XV. Yeast 1997 0.78
74 Inactivation and affinity-labeling of rat liver iodothyronine deiodinase with N-bromoacetyl-3,3',5-triiodothyronine. Biochem Biophys Res Commun 1984 0.78
75 Mechanisms of acquired resistance to methotrexate in a human squamous carcinoma cell line of the head and neck, exposed to different treatment schedules. Eur J Cancer 1991 0.78
76 Glycolytic activity in human red cell populations separated by a combination of density and counterflow centrifugation. Evidence for an improved separation of red cells according to age. Scand J Haematol 1986 0.78
77 Lipoamino acid conjugates of methotrexate with antitumor activity. J Pharm Sci 1998 0.78
78 Protection goals for residents in the vicinity of civil airports. Noise Health 2005 0.77
79 Online fluorescent method to assess BCRP/ABCG2 activity in suspension cells. Nucleosides Nucleotides Nucleic Acids 2004 0.77
80 Pyruvate kinase and the "high ATP syndrome". J Clin Invest 1984 0.77
81 Lack of cross-resistance between prednisolone and methotrexate in childhood acute lymphoblastic leukemia? A preliminary analysis. Adv Exp Med Biol 1999 0.77
82 Imputation accuracy is robust to cattle reference genome updates. Anim Genet 2014 0.77
83 In vitro activity of novel antifolates against human squamous carcinoma cell lines of the head and neck with inherent resistance to methotrexate. Int J Cancer 1992 0.76
84 Leucovorin rescue of human cancer and bone marrow cells following edatrexate or methotrexate. Biochem Pharmacol 1994 0.76
85 Cytotoxicity of methotrexate and trimetrexate and its reversal by folinic acid in human leukemic CCRF-CEM cells with carrier-mediated and receptor-mediated folate uptake. Leuk Res 1989 0.76
86 Hydrops fetalis associated with red cell pyruvate kinase deficiency. Genet Couns 1990 0.76
87 Bonding situation in Be[N(SiMe3)2]2 – an experimental and computational study. Chem Commun (Camb) 2015 0.76
88 Circumvention of methotrexate resistance in childhood leukemia subtypes by rationally designed antifolates. Blood 1999 0.76
89 Methotrexate analogues display enhanced inhibition of TNF-α production in whole blood from RA patients. Scand J Rheumatol 2013 0.76
90 The in vitro inactivation of thirteen beta-lactam antibiotics by other mechanisms than adsorption to faecal substance. Infection 1993 0.76
91 Increase of plasma and red cell cholesterol sulfate levels in induced hypothyroidism in man. Clin Chim Acta 1986 0.76
92 Folate homeostasis and antiproliferative activity of folates and antifolates. Nutrition 2001 0.75
93 Effectiveness of a physiotherapeutic exercise programme for chronic heart failure patients. Neth Heart J 2004 0.75
94 Detergent-insolubility during the biosynthesis of membrane folate receptor-2. Adv Exp Med Biol 1993 0.75
95 Disturbance of sleep by sonic booms. Sci Total Environ 1975 0.75
96 [Locoregional chemotherapy in the treatment of soft tissue neoplasms]. Acta Chir Belg 1969 0.75
97 [Benign liver tumor--apropos of 2 case reports]. Acta Chir Belg 1970 0.75
98 Age dependent behaviour of red cell glycolytic enzymes in haematological disorders. Br J Haematol 1985 0.75
99 [In memory of Professor Werner Klosterkötter]. Zentralbl Arbeitsmed Arbeitsschutz Prophyl 1978 0.75
100 Early diagnosis of recessive X-linked ichthyosis: elevation of cholesterol sulfate levels in placental sulfatase deficiency before the onset of skin symptoms. Pediatr Dermatol 1985 0.75
101 Predictors for noise sensitivity: how to use them for a prognostic test. Schriftenr Ver Wasser Boden Lufthyg 1993 0.75
102 [Demonstration of the effects of noise (at the same time a contribution to the determination of threshold values)]. Zentralbl Bakteriol Orig B 1971 0.75
103 Determination of inorganic sulphate in plasma by reversed-phase chromatography using ultraviolet detection and its application to plasma samples of patients receiving different types of haemodialysis. J Chromatogr 1985 0.75
104 [The effect of noise]. Zentralbl Arbeitsmed Arbeitsschutz Prophyl Ergonomie 1981 0.75
105 Glucose-6-phosphate isomerase deficiency-Nahariya: extreme in vitro and in vivo lability of the mutant enzyme. Isr J Med Sci 1984 0.75
106 [Identification of acute geriatric patients in the city of Hamburg ("direct data collection")]. Z Gerontol Geriatr 1998 0.75
107 Transformation of an L-cell line with the DNA coding for the reduced-folate/methotrexate transporter protein from a CCRF-CEM human leukemia cell line. Adv Exp Med Biol 1993 0.75
108 Intraoperative monitoring of brain tissue oxygen and carbon dioxide pressure in peritumoural oedema by stereotactic placement of multiparameter microsensors. Acta Neurochir Suppl 2002 0.75
109 [New generation behaviour therapy; new generation assessment measures; a review of currently available assessment measures]. Tijdschr Psychiatr 2015 0.75
110 [Decrease of autonomic reactions to noise through use of ear protectors]. Med Klin 1971 0.75
111 [Noise-caused changes of fine motoricity and sensations of annoyance dependent on certain personality dimensions]. Z Exp Angew Psychol 1965 0.75
112 Joint international evaluation of Milking Shorthorn dairy cattle for production traits. J Dairy Sci 2005 0.75
113 [Noise at the work place and its significance for human health]. Therapiewoche 1965 0.75
114 [Video display unit workplaces: costs and cost reduction in suitability and monitoring studies]. Zentralbl Arbeitsmed Arbeitsschutz Prophyl Ergonomie 1983 0.75
115 Reactions of a Zn(I) complex with group 14 azides--formation of zinc azide and zinc hexazene complexes. Chem Commun (Camb) 2014 0.75
116 Endolymphatic sac tumor: a case report and review of the literature. Surg Neurol 1997 0.75
117 Effects of noise on health. Ger Med Mon 1968 0.75
118 Significant decrease of titres of circulating IgG after oral intake of a preparation of Enterococcus faecalis in a group of ten healthy volunteers. Infection 1993 0.75
119 Variable pharmacodynamics of antifolates in squamous cell carcinoma of the head and neck. Adv Exp Med Biol 1993 0.75
120 [Noise as cause of disease]. Dtsch Med Wochenschr 1967 0.75
121 Treatment of retinal detachment in von Hippel-Lindau disease. Bull Soc Belge Ophtalmol 1986 0.75
122 Caenorhabditis elegans homologues of the CLN3 gene, mutated in juvenile neuronal ceroid lipofuscinosis. Eur J Paediatr Neurol 2001 0.75
123 A spectacular clinical problem: pheochromocytoma. Alaska Med 1966 0.75
124 [Drug therapy in colonic and rectal cancer]. Tijdschr Gastroenterol 1970 0.75
125 [Working among the mentally handicapped. A world to discover and to love]. Krankenpfl Soins Infirm 1985 0.75
126 Determinants of the therapeutic efficacy of thymidylate synthase inhibitors. Adv Exp Med Biol 1998 0.75
127 (Me)L2Zn2(μ-1,6-Ph2-N6) - a building block for new hexazene complexes. Dalton Trans 2015 0.75
128 [Postgastrectomy findings in the after care of 227 patients with stomach carcinoma]. Z Gastroenterol 1991 0.75
129 Synthesis, structure and dispersion interactions in bis(1,8-naphthalendiyl)distibine. Dalton Trans 2017 0.75
130 Efficacy and pharmacokinetics of teicoplanin in hemodialysis patients. Infection 1993 0.75
131 Antimetabolites in the treatment of arthritis: current status of the use of antimetabolites. Nucleosides Nucleotides Nucleic Acids 2004 0.75
132 241Am, 237Np, and 99Tc sorption on two United States subsoils from differing weathering intensity areas. Health Phys 1977 0.75
133 Membrane transport of methotrexate in a squamous carcinoma cell line adapted to low folate concentrations. Anticancer Res 1991 0.75
134 Factors associated with work resumption: a 5 year follow-up with cardiac patients. Int J Cardiol 1997 0.75
135 EEG-responses caused by environmental noise during sleep their relationships to exogenic and endogenic influences. Sci Total Environ 1978 0.75
136 [Pharmacologic studies on the antidegenerative effect of ademetionine in experimental arthritis in animals]. Arzneimittelforschung 1990 0.75
137 New CO-CO interaction potential tested by rovibrational calculations. J Chem Phys 2005 0.75