Published in J Biol Chem on June 18, 1999
Diversity of the mammalian sodium/proton exchanger SLC9 gene family. Pflugers Arch (2003) 2.89
Bone marrow stem cells contribute to repair of the ischemically injured renal tubule. J Clin Invest (2003) 2.81
Na+-H+ exchanger 3 (NHE3) is present in lipid rafts in the rabbit ileal brush border: a role for rafts in trafficking and rapid stimulation of NHE3. J Physiol (2001) 1.47
Luminal Na(+)/H (+) exchange in the proximal tubule. Pflugers Arch (2008) 1.21
Emerging roles of alkali cation/proton exchangers in organellar homeostasis. Curr Opin Cell Biol (2007) 1.20
Rho GTPases dictate the mobility of the Na/H exchanger NHE3 in epithelia: role in apical retention and targeting. Proc Natl Acad Sci U S A (2005) 1.20
NHE3 regulatory complexes. J Exp Biol (2009) 1.19
Renal NHE3 and NaPi2 partition into distinct membrane domains. Am J Physiol Cell Physiol (2009) 1.12
Angiotensin II stimulates trafficking of NHE3, NaPi2, and associated proteins into the proximal tubule microvilli. Am J Physiol Renal Physiol (2009) 1.08
Characterization of the regulation of renal Na+/H+ exchanger NHE3 by insulin. Am J Physiol Renal Physiol (2006) 1.04
Mechanisms of the regulation of the intestinal Na+/H+ exchanger NHE3. J Biomed Biotechnol (2010) 1.02
Inhibition of Na+-H+ exchanger-3 interferes with apical receptor-mediated endocytosis via vesicle fusion. J Physiol (2001) 0.98
Molecular mechanisms of receptor-mediated endocytosis in the renal proximal tubular epithelium. J Biomed Biotechnol (2010) 0.95
Activation of Na+/H+ exchanger NHE3 by angiotensin II is mediated by inositol 1,4,5-triphosphate (IP3) receptor-binding protein released with IP3 (IRBIT) and Ca2+/calmodulin-dependent protein kinase II. J Biol Chem (2010) 0.94
The calcineurin homologous protein-1 increases Na(+)/H(+) -exchanger 3 trafficking via ezrin phosphorylation. J Am Soc Nephrol (2009) 0.89
ClC transporters: discoveries and challenges in defining the mechanisms underlying function and regulation of ClC-5. Pflugers Arch (2010) 0.87
The endocytic receptor megalin and its associated proteins in proximal tubule epithelial cells. Membranes (Basel) (2014) 0.86
Coexpression of MAST205 inhibits the activity of Na+/H+ exchanger NHE3. Am J Physiol Renal Physiol (2005) 0.85
Microarray analysis of E9.5 reduced folate carrier (RFC1; Slc19a1) knockout embryos reveals altered expression of genes in the cubilin-megalin multiligand endocytic receptor complex. BMC Genomics (2008) 0.83
Calmodulin kinase II constitutively binds, phosphorylates, and inhibits brush border Na+/H+ exchanger 3 (NHE3) by a NHERF2 protein-dependent process. J Biol Chem (2012) 0.82
Impaired PTH-induced endocytotic down-regulation of the renal type IIa Na+/Pi-cotransporter in RAP-deficient mice with reduced megalin expression. Pflugers Arch (2003) 0.81
Receptor-Mediated Endocytosis in the Proximal Tubule. Annu Rev Physiol (2016) 0.81
Selective interaction of megalin with postsynaptic density-95 (PSD-95)-like membrane-associated guanylate kinase (MAGUK) proteins. Biochem J (2003) 0.81
Bone marrow cells contribute to tubular epithelium regeneration following acute kidney injury induced by mercuric chloride. Indian J Med Res (2012) 0.80
Proximal tubular NHEs: sodium, protons and calcium? Am J Physiol Renal Physiol (2013) 0.79
Elucidation of the etiology and characteristics of pink urine in young healthy subjects. Clin Exp Nephrol (2014) 0.78
Mechanisms of AT1a receptor-mediated uptake of angiotensin II by proximal tubule cells: a novel role of the multiligand endocytic receptor megalin. Am J Physiol Renal Physiol (2014) 0.78
Molecular mechanisms and regulation of urinary acidification. Compr Physiol (2014) 0.78
Lower urinary pH is useful for predicting renovascular disorder onset in patients with diabetes. BMJ Open Diabetes Res Care (2015) 0.78
Unique regulation of human Na+/H+ exchanger 3 (NHE3) by Nedd4-2 ligase that differs from non-primate NHE3s. J Biol Chem (2014) 0.77
The transcriptome of the Didelphis virginiana opossum kidney OK proximal tubule cell line. Am J Physiol Renal Physiol (2017) 0.75
Endocytic receptor LRP2/megalin-of holoprosencephaly and renal Fanconi syndrome. Pflugers Arch (2017) 0.75
Renal and intestinal absorptive defects in mice lacking the NHE3 Na+/H+ exchanger. Nat Genet (1998) 3.96
Modifier role of internal H+ in activating the Na+-H+ exchanger in renal microvillus membrane vesicles. Nature (1982) 3.49
Kinetic properties of the plasma membrane Na+-H+ exchanger. Annu Rev Physiol (1985) 3.08
Properties of the Na+-H+ exchanger in renal microvillus membrane vesicles. Am J Physiol (1980) 2.48
Amiloride inhibition of the Na+-H+ exchanger in renal microvillus membrane vesicles. Am J Physiol (1981) 2.33
The plasma membrane sodium-hydrogen exchanger and its role in physiological and pathophysiological processes. Circ Res (1985) 2.15
Identification of a chloride-formate exchanger expressed on the brush border membrane of renal proximal tubule cells. Proc Natl Acad Sci U S A (2001) 2.00
NHE3: a Na+/H+ exchanger isoform of renal brush border. Am J Physiol (1993) 1.93
Sodium/hydrogen exchanger gene defect in slow-wave epilepsy mutant mice. Cell (1997) 1.75
The Na+ gradient-dependent transport of D-glucose in renal brush border membranes. J Biol Chem (1975) 1.72
Stoichiometry of Na+-HCO-3 cotransport in basolateral membrane vesicles isolated from rabbit renal cortex. J Clin Invest (1987) 1.71
Interaction of NH4+ and Li+ with the renal microvillus membrane Na+-H+ exchanger. Am J Physiol (1981) 1.65
Mechanisms of active H+ secretion in the proximal tubule. Am J Physiol (1983) 1.59
Na+/HCO3-co-transport in basolateral membrane vesicles isolated from rabbit renal cortex. J Biol Chem (1986) 1.55
Sodium and chloride transport across rabbit ileal brush border. II. Evidence for Cl-HCO3 exchange and mechanism of coupling. Am J Physiol (1985) 1.49
Energy-dependence of phlorizin binding to isolated renal microvillus membranes. Evidence concerning the mechanism of coupling between the electrochemical Na+ gradient the sugar transport. J Membr Biol (1978) 1.47
Mechanism of proximal tubule bicarbonate absorption in NHE3 null mice. Am J Physiol (1999) 1.47
Monoclonal antibodies for high-resolution localization of NHE3 in adult and neonatal rat kidney. Am J Physiol (1997) 1.44
Interaction of external H+ with the Na+-H+ exchanger in renal microvillus membrane vesicles. J Biol Chem (1983) 1.41
Retinal pigmented epithelial cells induced to transdifferentiate to neurons by laminin. Nature (1987) 1.35
Sodium and chloride transport across rabbit ileal brush border. I. Evidence for Na-H exchange. Am J Physiol (1983) 1.31
Role of NHE3 in mediating renal brush border Na+-H+ exchange. Adaptation to metabolic acidosis. J Biol Chem (1996) 1.30
Membrane distribution of sodium-hydrogen and chloride-bicarbonate exchangers in crypt and villus cell membranes from rabbit ileum. J Clin Invest (1988) 1.30
Acute water shortage and health problems in Haiti. Lancet (1980) 1.24
Solution structure of the CBM10 cellulose binding module from Pseudomonas xylanase A. Biochemistry (2000) 1.20
Chloride/formate exchange with formic acid recycling: a mechanism of active chloride transport across epithelial membranes. Proc Natl Acad Sci U S A (1985) 1.20
Ontogeny of rabbit renal cortical NHE3 and NHE1: effect of glucocorticoids. Am J Physiol (1995) 1.18
Biosynthesis of the gp330/44-kDa Heymann nephritis antigenic complex: assembly takes place in the ER. Am J Physiol (1993) 1.16
Immunocytochemical characterization of Na(+)-H+ exchanger isoform NHE-1 in rabbit kidney. Am J Physiol (1992) 1.16
Specificity and modes of the anion exchanger in dog renal microvillus membranes. Am J Physiol (1983) 1.14
Isolation and cDNA cloning of Ksp-cadherin, a novel kidney-specific member of the cadherin multigene family. J Biol Chem (1995) 1.12
pH gradient-stimulated transport of urate and p-aminohippurate in dog renal microvillus membrane vesicles. J Clin Invest (1980) 1.09
Assembly of distinctive coated pit and microvillar microdomains in the renal brush border. Am J Physiol (1992) 1.08
Association of Na(+)-H(+) exchanger isoform NHE3 and dipeptidyl peptidase IV in the renal proximal tubule. J Biol Chem (2001) 1.06
Cl- transport via anion exchange in Necturus renal microvillus membranes. Am J Physiol (1984) 1.05
Ksp-cadherin gene promoter. II. Kidney-specific activity in transgenic mice. Am J Physiol (1999) 1.04
Hydrogen ion cotransport by the renal brush border glutamate transporter. Biochemistry (1983) 1.04
A novel Cellvibrio mixtus family 10 xylanase that is both intracellular and expressed under non-inducing conditions. Microbiology (2000) 1.04
Properties and physiologic roles of the plasma membrane sodium-hydrogen exchanger. J Clin Invest (1986) 1.03
Role of hydrogen bonding in the interaction between a xylan binding module and xylan. Biochemistry (2001) 1.02
Cholesterol potentiates ABCG2 activity in a heterologous expression system: improved in vitro model to study function of human ABCG2. J Pharmacol Exp Ther (2007) 1.02
Trp22, Trp24, and Tyr8 play a pivotal role in the binding of the family 10 cellulose-binding module from Pseudomonas xylanase A to insoluble ligands. Biochemistry (2000) 1.01
Ksp-cadherin gene promoter. I. Characterization and renal epithelial cell-specific activity. Am J Physiol (1999) 1.01
Active (9.6 s) and inactive (21 s) oligomers of NHE3 in microdomains of the renal brush border. J Biol Chem (2000) 1.01
Ionic mechanism of Na+-HCO3- cotransport in rabbit renal basolateral membrane vesicles. J Biol Chem (1989) 1.01
Determination of the coupling ratio for Na+ -H+ exchange in renal microvillus membrane vesicles. Biochim Biophys Acta (1982) 1.01
Anion exchange pathways for Cl- transport in rabbit renal microvillus membranes. Am J Physiol (1987) 1.00
Characterization of a cellulosome dockerin domain from the anaerobic fungus Piromyces equi. Nat Struct Biol (2001) 0.98
Immunolocalization of Ksp-cadherin in the adult and developing rabbit kidney. Am J Physiol (1999) 0.98
Leflunomide and its metabolite A771726 are high affinity substrates of BCRP: implications for drug resistance. Ann Rheum Dis (2008) 0.98
Effect of formate on volume reabsorption in the rabbit proximal tubule. J Clin Invest (1987) 0.97
Absence of Cl-OH exchange and NaCl cotransport in rabbit renal microvillus membrane vesicles. Am J Physiol (1984) 0.96
Pathways for oxalate transport in rabbit renal microvillus membrane vesicles. J Biol Chem (1996) 0.95
Harmaline inhibition of Na-dependent transport in renal microvillus membrane vesicles. Am J Physiol (1980) 0.94
Characterization of Na(+)-H+ exchangers on villus cells in rabbit ileum. Am J Physiol (1990) 0.94
Role of NHE isoforms in mediating bicarbonate reabsorption along the nephron. Am J Physiol Renal Physiol (2001) 0.93
Ion transport processes in apical membranes of epithelia. Fed Proc (1984) 0.92
Rabbit ileal brush-border membrane Cl-HCO3 exchanger is activated by an internal pH-sensitive modifier site. Am J Physiol (1990) 0.92
cDNA cloning and localization of a band 3-related protein from ileum. Am J Physiol (1992) 0.91
Urate transport via anion exchange in dog renal microvillus membrane vesicles. Am J Physiol (1983) 0.91
A possible role for the vascular membrane in retinal regeneration in Rana catesbienna tadpoles. Dev Biol (1987) 0.90
Transport of D-glucose by brush border membranes isolated from the renal cortex. Biochim Biophys Acta (1974) 0.90
Na-H exchange in rat liver basolateral but not canalicular plasma membrane vesicles. Am J Physiol (1986) 0.90
Effects of formate and oxalate on volume absorption in rat proximal tubule. Am J Physiol (1992) 0.89
[Electron microscopic study on immature and mature human placenta]. Arch Gynakol (1965) 0.89
Inactivation of the renal microvillus membrane Na+-H+ exchanger by histidine-specific reagents. J Biol Chem (1986) 0.89
Substrate and inhibitor specificity of anion exchangers on the brush border membrane of rabbit ileum. J Membr Biol (1985) 0.89
Interrelationships among quinidine, amiloride, and lithium as inhibitors of the renal Na+-H+ exchanger. J Biol Chem (1985) 0.88
Chloride transport in the mammalian proximal tubule. Pflugers Arch (1986) 0.88
Covalent modification of the renal Na+/H+ exchanger by N,N'-dicyclohexylcarbodiimide. J Biol Chem (1987) 0.87
Mechanism of increased potassium secretion in potassium loading and sodium deprivation. Am J Physiol (1980) 0.86
Evidence for carrier-mediated Cl-SO4 exchange in rabbit ileal basolateral membrane vesicles. Am J Physiol (1987) 0.86
Oxalate transport via the sulfate/HCO3 exchanger in rabbit renal basolateral membrane vesicles. J Biol Chem (1988) 0.86
Paradoxical effects of pyrazinoate and nicotinate on urate transport in dog renal microvillus membranes. J Clin Invest (1985) 0.86
cDNA cloning and immunolocalization of a Na(+)-H+ exchanger in LLC-PK1 renal epithelial cells. Am J Physiol (1991) 0.86
Identification and purification of a renal amiloride-binding protein with properties of the Na+-H+ exchanger. J Biol Chem (1989) 0.86
Immunochemical characterization of Na+/H+ exchanger isoform NHE4. Am J Physiol (1998) 0.85
Essential role of NHE3 in facilitating formate-dependent NaCl absorption in the proximal tubule. Am J Physiol Renal Physiol (2001) 0.85
Cetuximab, gemcitabine and capecitabine in patients with inoperable biliary tract cancer: a phase 2 study. Eur J Cancer (2013) 0.84
cDNA cloning and chromosomal localization of the human and mouse isoforms of Ksp-cadherin. Genomics (1998) 0.84
Membrane topology of NHE3. Epitopes within the carboxyl-terminal hydrophilic domain are exoplasmic. J Biol Chem (1998) 0.83
Interaction of macrocyclic lactones with the multidrug transporters: the bases of the pharmacokinetics of lipid-like drugs. Curr Drug Metab (2009) 0.83
Effect of metabolic acidosis on NaCl transport in the proximal tubule. Am J Physiol (1998) 0.83
Effects of inhibitors on anion exchangers in rabbit renal brush border membrane vesicles. J Biol Chem (1994) 0.83
Glucose and alanine inhibition of phosphate transport in renal microvillus membrane vesicles. Am J Physiol (1982) 0.83
Dissociation of proximal tubular glucose and Na+ reabsorption by amphotericin B. Am J Physiol (1979) 0.83
Cation specificity and modes of the Na+:CO3(2-):HCO3- cotransporter in renal basolateral membrane vesicles. J Biol Chem (1991) 0.82
Effects of acetazolamide on Na+-HCO-3 cotransport in basolateral membrane vesicles isolated from rabbit renal cortex. J Clin Invest (1989) 0.82
Na(+)-H+ exchanger and its role in essential hypertension and diabetes mellitus. Diabetes Care (1991) 0.82
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy, genetic homogeneity, and mapping of the locus within a 2-cM interval. Am J Hum Genet (1996) 0.82
Integrative plasmid vector for constructing single-copy reporter systems to study gene regulation in Rhizobium meliloti and related species. Plasmid (2004) 0.81
Decreased blood catalase activity is not related to specific beta-thalassemia mutations in Hungary. Int J Lab Hematol (2011) 0.81
Cloning, sequence, and tissue distribution of a rabbit renal Na+/H+ exchanger transcript. Biochim Biophys Acta (1991) 0.81
Role of sodium/hydrogen exchanger isoform NHE3 in fluid secretion and absorption in mouse and rat cholangiocytes. Am J Physiol Gastrointest Liver Physiol (2001) 0.81
Stimulation of chloride transport by cAMP in rat proximal tubules. Am J Physiol (1995) 0.80
Identifying secondary active solute transport in epithelia. Am J Physiol (1981) 0.80