Published in J Neurosci on June 15, 1999
UNC-13 is required for synaptic vesicle fusion in C. elegans. Nat Neurosci (1999) 4.39
Defects in synaptic vesicle docking in unc-18 mutants. Nat Neurosci (2003) 2.11
Munc13-1 acts as a priming factor for large dense-core vesicles in bovine chromaffin cells. EMBO J (2000) 1.98
Mutations that rescue the paralysis of Caenorhabditis elegans ric-8 (synembryn) mutants activate the G alpha(s) pathway and define a third major branch of the synaptic signaling network. Genetics (2004) 1.66
Convergent, RIC-8-dependent Galpha signaling pathways in the Caenorhabditis elegans synaptic signaling network. Genetics (2004) 1.47
Expression of multiple UNC-13 proteins in the Caenorhabditis elegans nervous system. Mol Biol Cell (2000) 1.38
Positive selection of Caenorhabditis elegans mutants with increased stress resistance and longevity. Genetics (2003) 1.37
Multiple roles for the actin cytoskeleton during regulated exocytosis. Cell Mol Life Sci (2012) 1.35
Tomosyn inhibits priming of large dense-core vesicles in a calcium-dependent manner. Proc Natl Acad Sci U S A (2004) 1.24
Munc18-1 regulates early and late stages of exocytosis via syntaxin-independent protein interactions. Mol Biol Cell (2004) 1.07
Phorbol esters and neurotransmitter release: more than just protein kinase C? Br J Pharmacol (2003) 1.03
Goalpha regulates volatile anesthetic action in Caenorhabditis elegans. Genetics (2001) 1.03
Resolving the function of distinct Munc18-1/SNARE protein interaction modes in a reconstituted membrane fusion assay. J Biol Chem (2011) 1.02
Initiation of male sperm-transfer behavior in Caenorhabditis elegans requires input from the ventral nerve cord. BMC Biol (2006) 1.01
The tyrosine phosphorylation of Munc18c induces a switch in binding specificity from syntaxin 4 to Doc2beta. J Biol Chem (2008) 0.98
UNC-18 modulates ethanol sensitivity in Caenorhabditis elegans. Mol Biol Cell (2008) 0.96
Rules of nonallelic noncomplementation at the synapse in Caenorhabditis elegans. Genetics (2001) 0.93
Genes required for cellular UNC-6/netrin localization in Caenorhabditis elegans. Genetics (2010) 0.87
Regulation of syntaxin1A-munc18 complex for SNARE pairing in HEK293 cells. J Physiol (2004) 0.83
Platelet granule exocytosis: a comparison with chromaffin cells. Front Endocrinol (Lausanne) (2013) 0.83
PKC-2 phosphorylation of UNC-18 Ser322 in AFD neurons regulates temperature dependency of locomotion. J Neurosci (2012) 0.83
The pre-synaptic Munc13-1 binds alcohol and modulates alcohol self-administration in Drosophila. J Neurochem (2013) 0.83
Calcium-dependent activator protein for secretion 1 (CAPS1) binds to syntaxin-1 in a distinct mode from Munc13-1. J Biol Chem (2013) 0.81
Structure-function study of mammalian Munc18-1 and C. elegans UNC-18 implicates domain 3b in the regulation of exocytosis. PLoS One (2011) 0.81
Cyclin-dependent kinase 5 regulates degranulation in human eosinophils. Immunology (2015) 0.80
Crystal structure of the Habc domain of neuronal syntaxin from the squid Loligo pealei reveals conformational plasticity at its C-terminus. BMC Struct Biol (2004) 0.78
Pharyngeal pumping in Caenorhabditis elegans depends on tonic and phasic signaling from the nervous system. Sci Rep (2016) 0.77
Identification of a Munc13-sensitive step in chromaffin cell large dense-core vesicle exocytosis. Elife (2015) 0.77
Identification and characterization of syntaxin 1 antisense variants in Limulus polyphemus. Cell Mol Neurobiol (2006) 0.77
Conformational change of syntaxin linker region induced by Munc13s initiates SNARE complex formation in synaptic exocytosis. EMBO J (2017) 0.75
UNC-18 and Tomosyn antagonistically control synaptic vesicle priming downstream of UNC-13 in C. elegans. J Neurosci (2017) 0.75
Resveratrol inhibits phorbol ester-induced membrane translocation of presynaptic Munc13-1. Biochim Biophys Acta (2017) 0.75
A Calcium, Diacylglycerol Stimulated Protein Kinase C, C. elegans PKC-2, Links Thermal Signals to Learned Behavior by Acting in a Sensory Neuron and Intestinal Cells. Mol Cell Biol (2017) 0.75
In vitro and in vivo activity of DL-8280, a new oxazine derivative. Antimicrob Agents Chemother (1982) 21.31
Transient left ventricular apical ballooning without coronary artery stenosis: a novel heart syndrome mimicking acute myocardial infarction. Angina Pectoris-Myocardial Infarction Investigations in Japan. J Am Coll Cardiol (2001) 12.56
Rad51 protein involved in repair and recombination in S. cerevisiae is a RecA-like protein. Cell (1992) 10.78
Infection of HTLV-III/LAV in HTLV-I-carrying cells MT-2 and MT-4 and application in a plaque assay. Science (1985) 10.71
Tree allometry and improved estimation of carbon stocks and balance in tropical forests. Oecologia (2005) 10.52
Crystal structure of the calcium pump of sarcoplasmic reticulum at 2.6 A resolution. Nature (2000) 9.44
Rad51-deficient vertebrate cells accumulate chromosomal breaks prior to cell death. EMBO J (1998) 6.65
Goalpha and diacylglycerol kinase negatively regulate the Gqalpha pathway in C. elegans. Neuron (1999) 5.63
Cloning of human, mouse and fission yeast recombination genes homologous to RAD51 and recA. Nat Genet (1993) 4.96
Organization of the recA gene of Escherichia coli. Proc Natl Acad Sci U S A (1980) 4.90
Mutants of Escherichia coli lacking in highly penicillin-sensitive D-alanine carboxypeptidase activity. Proc Natl Acad Sci U S A (1977) 4.44
Synaptic function is impaired but not eliminated in C. elegans mutants lacking synaptotagmin. Cell (1993) 4.20
Efficient generation of recombinant adenoviruses using adenovirus DNA-terminal protein complex and a cosmid bearing the full-length virus genome. Proc Natl Acad Sci U S A (1996) 3.85
Complex formation and functional versatility of Mre11 of budding yeast in recombination. Cell (1998) 3.80
A DNA damage response pathway controlled by Tel1 and the Mre11 complex. Mol Cell (2001) 3.65
Localization and mechanism of secretion of B-type natriuretic peptide in comparison with those of A-type natriuretic peptide in normal subjects and patients with heart failure. Circulation (1994) 3.63
Nucleotide sequence of the lexA gene of E. coli. Cell (1981) 3.61
Interaction of Mre11 and Rad50: two proteins required for DNA repair and meiosis-specific double-strand break formation in Saccharomyces cerevisiae. Genetics (1995) 3.57
Studies on radiation-sensitive mutants of E. coli. I. Mutants defective in the repair synthesis. Mol Gen Genet (1968) 3.55
On the process of cellular division in Escherichia coli: nucleotide sequence of the gene for penicillin-binding protein 3. Mol Gen Genet (1983) 3.43
A genetic selection for Caenorhabditis elegans synaptic transmission mutants. Proc Natl Acad Sci U S A (1996) 3.43
T-786-->C mutation in the 5'-flanking region of the endothelial nitric oxide synthase gene is associated with coronary spasm. Circulation (1999) 3.41
Cinemicrographic study of tissue cell cultures infected with Shigella flexneri. Jpn J Med Sci Biol (1968) 3.12
An essential gene, ESR1, is required for mitotic cell growth, DNA repair and meiotic recombination in Saccharomyces cerevisiae. Nucleic Acids Res (1994) 3.05
Characteristics of purified recA protein and the regulation of its synthesis in vivo. Cold Spring Harb Symp Quant Biol (1979) 2.93
Identification of new genes required for meiotic recombination in Saccharomyces cerevisiae. Genetics (1993) 2.87
Experimental investigation of geologically produced antineutrinos with KamLAND. Nature (2005) 2.75
Hyperglycemia rapidly suppresses flow-mediated endothelium-dependent vasodilation of brachial artery. J Am Coll Cardiol (1999) 2.75
Isolation of a mutant of Escherichia coli lacking penicillin-sensitive D-alanine carboxypeptidase IA. Proc Natl Acad Sci U S A (1978) 2.69
Synaptic transmission deficits in Caenorhabditis elegans synaptobrevin mutants. J Neurosci (1998) 2.57
Primary structure of the RAD52 gene in Saccharomyces cerevisiae. Mol Cell Biol (1984) 2.56
Tumor promoter, TPA, enhances replication of HTLV-III/LAV. Virology (1986) 2.51
Activation of preformed EGF receptor dimers by ligand-induced rotation of the transmembrane domain. J Mol Biol (2001) 2.50
A novel mre11 mutation impairs processing of double-strand breaks of DNA during both mitosis and meiosis. Mol Cell Biol (1998) 2.46
Exo1 roles for repair of DNA double-strand breaks and meiotic crossing over in Saccharomyces cerevisiae. Mol Biol Cell (2000) 2.44
Differential susceptibility to the acquired immunodeficiency syndrome retrovirus in cloned cells of human leukemic T-cell line Molt-4. J Virol (1986) 2.40
Comparison of atopic cough with cough variant asthma: is atopic cough a precursor of asthma? Thorax (2003) 2.37
Structural genes of ATP-dependent deoxyribonuclease of Escherichia coli. Nat New Biol (1972) 2.32
Characterization of the roles of the Saccharomyces cerevisiae RAD54 gene and a homologue of RAD54, RDH54/TID1, in mitosis and meiosis. Genetics (1997) 2.31
Structural analysis of the umu operon required for inducible mutagenesis in Escherichia coli. Proc Natl Acad Sci U S A (1985) 2.30
Predominant recognition of human T cell leukemia virus type I (HTLV-I) pX gene products by human CD8+ cytotoxic T cells directed against HTLV-I-infected cells. Int Immunol (1991) 2.27
The Caenorhabditis elegans unc-17 gene: a putative vesicular acetylcholine transporter. Science (1993) 2.26
RAB22 and RAB163/mouse BRCA2: proteins that specifically interact with the RAD51 protein. Proc Natl Acad Sci U S A (1997) 2.23
Regulation of SOS functions: purification of E. coli LexA protein and determination of its specific site cleaved by the RecA protein. Cell (1981) 2.20
Caenorhabditis elegans mutants resistant to inhibitors of acetylcholinesterase. Genetics (1995) 2.16
Hyperventilation as a specific test for diagnosis of coronary artery spasm. Am J Cardiol (1997) 2.16
Mutations in ATP2C1, encoding a calcium pump, cause Hailey-Hailey disease. Nat Genet (2000) 2.09
Menstrual cyclic variation of myocardial ischemia in premenopausal women with variant angina. Ann Intern Med (2001) 2.08
Nitric oxide activity is deficient in spasm arteries of patients with coronary spastic angina. Circulation (1996) 2.06
The cat-1 gene of Caenorhabditis elegans encodes a vesicular monoamine transporter required for specific monoamine-dependent behaviors. J Neurosci (1999) 2.06
Molecular cloning of human eotaxin, an eosinophil-selective CC chemokine, and identification of a specific eosinophil eotaxin receptor, CC chemokine receptor 3. J Biol Chem (1996) 2.04
Localization of RecA-like recombination proteins on chromosomes of the lily at various meiotic stages. Genes Dev (1995) 2.04
Different secretion patterns of atrial natriuretic peptide and brain natriuretic peptide in patients with congestive heart failure. Circulation (1993) 2.04
WT1 as a new prognostic factor and a new marker for the detection of minimal residual disease in acute leukemia. Blood (1994) 2.03
Randomised clinical trial: prevention of recurrence of peptic ulcers by rabeprazole in patients taking low-dose aspirin. Aliment Pharmacol Ther (2014) 2.03
Racial differences in alcohol sensitivity: a new hypothesis. Hum Genet (1979) 2.01
Liver alcohol dehydrogenase and aldehyde dehydrogenase in the Japanese: isozyme variation and its possible role in alcohol intoxication. Am J Hum Genet (1980) 1.97
Aldehyde dehydrogenase deficiency as cause of facial flushing reaction to alcohol in Japanese. Lancet (1981) 1.92
Protective roles of mast cells against enterobacterial infection are mediated by Toll-like receptor 4. J Immunol (2001) 1.90
Eosinophilic tracheobronchitis and airway cough hypersensitivity in chronic non-productive cough. Clin Exp Allergy (2000) 1.90
Remnant lipoprotein levels in fasting serum predict coronary events in patients with coronary artery disease. Circulation (1999) 1.89
A chicken RAD51 homologue is expressed at high levels in lymphoid and reproductive organs. Nucleic Acids Res (1993) 1.89
Choline acetyltransferase-deficient mutants of the nematode Caenorhabditis elegans. Genetics (1984) 1.89
RecA-like recombination proteins in eukaryotes: functions and structures of RAD51 genes. Cold Spring Harb Symp Quant Biol (1993) 1.86
Antimycoplasmal activity of ofloxacin (DL-8280). Antimicrob Agents Chemother (1983) 1.86
Overexpression, solubilization and refolding of a genetically engineered derivative of the penicillin-binding protein 3 of Escherichia coli K12. Mol Microbiol (1988) 1.84
Increased plasma levels of brain natriuretic peptide in patients with acute myocardial infarction. Circulation (1993) 1.82
Efficient targeting of gene expression in chick embryos by microelectroporation. Dev Growth Differ (1999) 1.81
Generation and characterization of a human immunodeficiency virus type 1 (HIV-1) mutant resistant to an HIV-1 protease inhibitor. J Virol (1994) 1.80
OPC-41061, a highly potent human vasopressin V2-receptor antagonist: pharmacological profile and aquaretic effect by single and multiple oral dosing in rats. J Pharmacol Exp Ther (1998) 1.74
Sequence analysis of the complete Caenorhabditis elegans myosin heavy chain gene family. J Mol Biol (1989) 1.72
Aberrant overexpression of the Wilms tumor gene (WT1) in human leukemia. Blood (1997) 1.72
Functional domains of Escherichia coli recA protein deduced from the mutational sites in the gene. Mol Gen Genet (1984) 1.71
The Saccharomyces cerevisiae MER3 gene, encoding a novel helicase-like protein, is required for crossover control in meiosis. EMBO J (1999) 1.71
Isolation and characterization of proteinase from Candida albicans: substrate specificity. J Invest Dermatol (1984) 1.70
Flow cytometric single-cell analysis of cytokine production by CD4+ T cells in synovial tissue and peripheral blood from patients with rheumatoid arthritis. Arthritis Rheum (1998) 1.69
Evaluation of the effects of peptide antibiotics human beta-defensins-1/-2 and LL-37 on histamine release and prostaglandin D(2) production from mast cells. Eur J Immunol (2001) 1.68
Expression of processed envelope protein of hepatitis C virus in mammalian and insect cells. J Virol (1992) 1.68
Inhibition of replication and cytopathic effect of human T cell lymphotropic virus type III/lymphadenopathy-associated virus by 3'-azido-3'-deoxythymidine in vitro. Antimicrob Agents Chemother (1986) 1.66
Generation of neutralization-resistant HIV-1 in vitro due to amino acid interchanges of third hypervariable env region. J Immunol (1990) 1.66
Primate cutaneous thermal nociceptors. J Physiol (1971) 1.64
Pathogenic properties of "enteropathogenic" Escherichia coli from diarrheal children and adults. Jpn J Med Sci Biol (1968) 1.62
The synovial expression and serum levels of interleukin-6, interleukin-11, leukemia inhibitory factor, and oncostatin M in rheumatoid arthritis. Arthritis Rheum (1997) 1.60
Clinical and pathological differences between Mikulicz's disease and Sjögren's syndrome. Rheumatology (Oxford) (2004) 1.60
A missense Glu298Asp variant in the endothelial nitric oxide synthase gene is associated with coronary spasm in the Japanese. Hum Genet (1998) 1.59
Improvement of endothelial function and insulin sensitivity with vitamin C in patients with coronary spastic angina: possible role of reactive oxygen species. J Am Coll Cardiol (2000) 1.59
Multiple myeloma preceding the development of chronic myelogenous leukemia. Int J Hematol (1999) 1.57
RIC-8 (Synembryn): a novel conserved protein that is required for G(q)alpha signaling in the C. elegans nervous system. Neuron (2000) 1.57
Possible participation of autocrine and paracrine vascular endothelial growth factors in hypoxia-induced proliferation of endothelial cells and pericytes. J Biol Chem (1995) 1.55
Correlative physiological and morphological studies of rapidly adapting mechanoreceptors in cat's glabrous skin. J Physiol (1977) 1.55
Global oral health of older people--call for public health action. Community Dent Health (2010) 1.54
Association of the missense Glu298Asp variant of the endothelial nitric oxide synthase gene with myocardial infarction. J Am Coll Cardiol (1998) 1.53
Effect of H1 receptor stimulation on coronary artery diameter in patients with variant angina: comparison with effect of acetylcholine. J Am Coll Cardiol (1991) 1.53
Nuclear localization of the truncated hepatitis C virus core protein with its hydrophobic C terminus deleted. J Gen Virol (1995) 1.52
Responses of angiographically normal human coronary arteries to intracoronary injection of acetylcholine by age and segment. Possible role of early coronary atherosclerosis. Circulation (1990) 1.52
Bacteriophage lambda DNA with different structures found in infected cells. J Mol Biol (1967) 1.52
Induction of various blood-brain barrier properties in non-neural endothelial cells by close apposition to co-cultured astrocytes. Glia (1997) 1.51
The MRE4 gene encodes a novel protein kinase homologue required for meiotic recombination in Saccharomyces cerevisiae. Nucleic Acids Res (1992) 1.51
Human cytotoxic T-lymphocyte responses specific for peptides of the wild-type Wilms' tumor gene (WT1 ) product. Immunogenetics (2000) 1.51