Published in Bioinformatics on May 01, 1999
Computational detection and location of transcription start sites in mammalian genomic DNA. Genome Res (2002) 7.89
Genetic predisposition to elevated serum thyrotropin is associated with exceptional longevity. J Clin Endocrinol Metab (2009) 2.04
Polymorphisms in the taste receptor gene (Tas1r3) region are associated with saccharin preference in 30 mouse strains. J Neurosci (2004) 2.03
Performance assessment of promoter predictions on ENCODE regions in the EGASP experiment. Genome Biol (2006) 2.02
The broad-spectrum blast resistance gene Pi9 encodes a nucleotide-binding site-leucine-rich repeat protein and is a member of a multigene family in rice. Genetics (2005) 2.01
First pass annotation of promoters on human chromosome 22. Genome Res (2001) 1.99
ProSOM: core promoter prediction based on unsupervised clustering of DNA physical profiles. Bioinformatics (2008) 1.91
Generic eukaryotic core promoter prediction using structural features of DNA. Genome Res (2007) 1.80
Preservation of intracellular renin expression is insufficient to compensate for genetic loss of secreted renin. Hypertension (2009) 1.68
An Arabidopsis GPI-anchor plasmodesmal neck protein with callose binding activity and potential to regulate cell-to-cell trafficking. Plant Cell (2009) 1.65
Towards a molecular dynamics consensus view of B-DNA flexibility. Nucleic Acids Res (2008) 1.56
Determining promoter location based on DNA structure first-principles calculations. Genome Biol (2007) 1.44
PromH: Promoters identification using orthologous genomic sequences. Nucleic Acids Res (2003) 1.41
Plant promoter prediction with confidence estimation. Nucleic Acids Res (2005) 1.27
Alterations in cardiac DNA methylation in human dilated cardiomyopathy. EMBO Mol Med (2013) 1.23
Toward a gold standard for promoter prediction evaluation. Bioinformatics (2009) 1.17
Human cytomegalovirus DNA replication requires transcriptional activation via an IE2- and UL84-responsive bidirectional promoter element within oriLyt. J Virol (2004) 1.16
Epigenetic modulation of miR-122 facilitates human embryonic stem cell self-renewal and hepatocellular carcinoma proliferation. PLoS One (2011) 1.11
Consensus promoter identification in the human genome utilizing expressed gene markers and gene modeling. Genome Res (2002) 1.09
Cloning and expression of the human T-type channel Ca(v)3.3: insights into prepulse facilitation. Biophys J (2002) 1.09
A rare Asian founder polymorphism of Raptor may explain the high prevalence of Moyamoya disease among East Asians and its low prevalence among Caucasians. Environ Health Prev Med (2009) 1.08
Transcriptional regulation of the human LINE-1 retrotransposon L1.2B. Mol Genet Genomics (2003) 1.04
VILIP-1 downregulation in non-small cell lung carcinomas: mechanisms and prediction of survival. PLoS One (2008) 1.00
Galaxy tools and workflows for sequence analysis with applications in molecular plant pathology. PeerJ (2013) 1.00
Human pol II promoter prediction: time series descriptors and machine learning. Nucleic Acids Res (2005) 0.98
Hormonal regulation of cardiac KCNE2 gene expression. Mol Cell Endocrinol (2008) 0.98
Organization and expression of the SLC36 cluster of amino acid transporter genes. Mamm Genome (2004) 0.94
Methylation-associated silencing of MicroRNA-335 contributes tumor cell invasion and migration by interacting with RASA1 in gastric cancer. Am J Cancer Res (2014) 0.90
A genome-wide association study identifies a region at chromosome 12 as a potential susceptibility locus for restenosis after percutaneous coronary intervention. Hum Mol Genet (2011) 0.87
Human Pol II promoter recognition based on primary sequences and free energy of dinucleotides. BMC Bioinformatics (2008) 0.87
Aberrant methylation and reduced expression of LHX9 in malignant gliomas of childhood. Neoplasia (2009) 0.85
Genome-wide analysis of the Hsf family in soybean and functional identification of GmHsf-34 involvement in drought and heat stresses. BMC Genomics (2014) 0.85
Analysis of transcriptional regulation of the human miR-17-92 cluster; evidence for involvement of Pim-1. Int J Mol Sci (2013) 0.85
Pol II promoter prediction using characteristic 4-mer motifs: a machine learning approach. BMC Bioinformatics (2008) 0.84
Tumor-suppressive miR148a is silenced by CpG island hypermethylation in IDH1-mutant gliomas. Clin Cancer Res (2014) 0.83
Experimental verification of a predicted intronic microRNA in human NGFR gene with a potential pro-apoptotic function. PLoS One (2012) 0.83
Identification and characterization of putative methylation targets in the MAOA locus using bioinformatic approaches. Epigenetics (2010) 0.83
Non-homologous end-joining pathway associated with occurrence of myocardial infarction: gene set analysis of genome-wide association study data. PLoS One (2013) 0.82
GANN: genetic algorithm neural networks for the detection of conserved combinations of features in DNA. BMC Bioinformatics (2005) 0.82
SIP1 is downregulated in hepatocellular carcinoma by promoter hypermethylation. BMC Cancer (2011) 0.82
A long non-coding RNA promotes full activation of adult gene expression in the chicken α-globin domain. Epigenetics (2013) 0.81
Molecular evolution of A-kinase anchoring protein (AKAP)-7: implications in comparative PKA compartmentalization. BMC Evol Biol (2012) 0.81
Latent transforming growth factor β-binding protein 4 is downregulated in esophageal cancer via promoter methylation. PLoS One (2013) 0.81
Predicting promoter activities of primary human DNA sequences. Nucleic Acids Res (2011) 0.81
Multiple mechanisms contribute to leakiness of a frameshift mutation in canine cone-rod dystrophy. PLoS One (2012) 0.80
Cloning and characterization of the human beta2-glycoprotein I (beta2-GPI) gene promoter: roles of the atypical TATA box and hepatic nuclear factor-1alpha in regulating beta2-GPI promoter activity. Biochem J (2004) 0.80
Quadruplex-forming sequences occupy discrete regions inside plant LTR retrotransposons. Nucleic Acids Res (2013) 0.80
Cis-regulatory functions of overlapping HIF-1alpha/E-box/AP-1-like sequences of CD164. BMC Mol Biol (2011) 0.80
Arxes: retrotransposed genes required for adipogenesis. Nucleic Acids Res (2010) 0.80
The polyembryo gene (OsPE) in rice. Funct Integr Genomics (2009) 0.79
Prediction for human transcription start site using diversity measure with quadratic discriminant. Bioinformation (2008) 0.79
Human RFP2 gene promoter: unique structure and unusual strength. Biochem Biophys Res Commun (2006) 0.79
In silico comparative genomic analysis of GABAA receptor transcriptional regulation. BMC Genomics (2007) 0.79
Prediction of plant promoters based on hexamers and random triplet pair analysis. Algorithms Mol Biol (2011) 0.78
High sensitivity TSS prediction: estimates of locations where TSS cannot occur. PLoS One (2010) 0.77
An ANN-GA model based promoter prediction in Arabidopsis thaliana using tilling microarray data. Bioinformation (2011) 0.77
Identification of a secondary promoter of CASP8 and its related transcription factor PURα. Int J Oncol (2014) 0.77
Rule-based knowledge acquisition method for promoter prediction in human and Drosophila species. ScientificWorldJournal (2014) 0.76
Sequencing and transcriptional analysis of the biosynthesis gene cluster of abscisic acid-producing Botrytis cinerea. Int J Mol Sci (2014) 0.76
bTSSfinder: a novel tool for the prediction of promoters in Cyanobacteria and Escherichia coli. Bioinformatics (2016) 0.76
Genome-Wide Analysis of the RAV Family in Soybean and Functional Identification of GmRAV-03 Involvement in Salt and Drought Stresses and Exogenous ABA Treatment. Front Plant Sci (2017) 0.75
Variants in ANRIL gene correlated with its expression contribute to myocardial infarction risk. Oncotarget (2017) 0.75
ΔN-ASPP2, a novel isoform of the ASPP2 tumor suppressor, promotes cellular survival. Biochem Biophys Res Commun (2016) 0.75
Cloning, characterization, and expression analysis of the pig (Sus scrofa) C1q tumor necrosis factor-related protein-5 gene. Mol Vis (2012) 0.75
Recognition of prokaryotic and eukaryotic promoters using convolutional deep learning neural networks. PLoS One (2017) 0.75
Genome-wide identification of small RNAs in Bifidobacterium animalis subsp. lactis KLDS 2.0603 and their regulation role in the adaption to gastrointestinal environment. PLoS One (2015) 0.75
Functional Operons in Secondary Metabolic Gene Clusters in Glarea lozoyensis (Fungi, Ascomycota, Leotiomycetes). MBio (2015) 0.75
Plasmid-Encoded RepA Proteins Specifically Autorepress Individual repABC Operons in the Multipartite Rhizobium leguminosarum bv. trifolii Genome. PLoS One (2015) 0.75
TIPR: transcription initiation pattern recognition on a genome scale. Bioinformatics (2015) 0.75
Evolution of the F-box gene family in Euarchontoglires: gene number variation and selection patterns. PLoS One (2014) 0.75
Current functional metagenomic approaches only expand the existing protease sequence space, but does not presently add any novelty to it. Curr Microbiol (2014) 0.75
MYC-dependent recruitment of RUNX1 and GATA2 on the SET oncogene promoter enhances PP2A inactivation in acute myeloid leukemia. Oncotarget (2016) 0.75
IL-4 upregulates cyclooxygenase-1 expression in macrophages. J Biol Chem (2017) 0.75