Published in PLoS One on May 31, 2013
Modeling autosomal recessive cutis laxa type 1C in mice reveals distinct functions for Ltbp-4 isoforms. Dis Model Mech (2015) 0.78
Function of Ltbp-4L and fibulin-4 in survival and elastogenesis in mice. Dis Model Mech (2016) 0.75
HBx-related long non-coding RNA MALAT1 promotes cell metastasis via up-regulating LTBP3 in hepatocellular carcinoma. Am J Cancer Res (2017) 0.75
The human genome browser at UCSC. Genome Res (2002) 168.23
Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int J Cancer (2010) 90.16
Databases on transcriptional regulation: TRANSFAC, TRRD and COMPEL. Nucleic Acids Res (1998) 14.63
MethPrimer: designing primers for methylation PCRs. Bioinformatics (2002) 14.48
Cancer treatment and survivorship statistics, 2012. CA Cancer J Clin (2012) 14.47
Efficacy of azacitidine compared with that of conventional care regimens in the treatment of higher-risk myelodysplastic syndromes: a randomised, open-label, phase III study. Lancet Oncol (2009) 12.41
MatInspector and beyond: promoter analysis based on transcription factor binding sites. Bioinformatics (2005) 11.75
Cancer epigenetics: from mechanism to therapy. Cell (2012) 7.74
Latent transforming growth factor beta-binding protein 1 interacts with fibrillin and is a microfibril-associated protein. J Biol Chem (2002) 3.92
Tgf-beta superfamily signaling in embryonic development and homeostasis. Dev Cell (2009) 3.51
Latent TGF-β structure and activation. Nature (2011) 3.42
Epidemiology and pathogenesis of esophageal cancer. Semin Radiat Oncol (2007) 3.18
E2F-4 and E2F-5, two members of the E2F family, are expressed in the early phases of the cell cycle. Proc Natl Acad Sci U S A (1995) 2.99
Transforming growth factor beta-induced phosphorylation of Smad3 is required for growth inhibition and transcriptional induction in epithelial cells. Proc Natl Acad Sci U S A (1997) 2.97
Promoter2.0: for the recognition of PolII promoter sequences. Bioinformatics (1999) 2.96
c-Myc promotes differentiation of human epidermal stem cells. Genes Dev (1997) 2.37
E2F4 is essential for normal erythrocyte maturation and neonatal viability. Mol Cell (2000) 2.21
Disruption of the gene encoding the latent transforming growth factor-beta binding protein 4 (LTBP-4) causes abnormal lung development, cardiomyopathy, and colorectal cancer. Genes Dev (2002) 2.13
Specific sequence motif of 8-Cys repeats of TGF-beta binding proteins, LTBPs, creates a hydrophobic interaction surface for binding of small latent TGF-beta. Mol Biol Cell (2000) 2.01
Loss of E2F4 activity leads to abnormal development of multiple cellular lineages. Mol Cell (2000) 1.86
Latency, activation, and binding proteins of TGF-beta. Microsc Res Tech (2001) 1.70
Dual role for the latent transforming growth factor-beta binding protein in storage of latent TGF-beta in the extracellular matrix and as a structural matrix protein. J Cell Biol (1995) 1.58
The role of matrix metalloproteinases (MMPs) and their inhibitors (TIMPs) in the development of esophageal cancer. Folia Histochem Cytobiol (2012) 1.40
Mutations in LTBP4 cause a syndrome of impaired pulmonary, gastrointestinal, genitourinary, musculoskeletal, and dermal development. Am J Hum Genet (2009) 1.34
Epigenetic gene silencing in cancer. J Clin Invest (2000) 1.28
Blocking sp1 transcription factor broadly inhibits extracellular matrix gene expression in vitro and in vivo: implications for the treatment of tissue fibrosis. J Invest Dermatol (2001) 1.22
Dual functions for LTBP in lung development: LTBP-4 independently modulates elastogenesis and TGF-beta activity. J Cell Physiol (2009) 1.14
Independent promoters regulate the expression of two amino terminally distinct forms of latent transforming growth factor-beta binding protein-1 (LTBP-1) in a cell type-specific manner. J Biol Chem (1999) 1.12
E2f4 is required for normal development of the airway epithelium. Dev Biol (2007) 1.11
Expression and prognostic significance of TGF-beta isotypes, latent TGF-beta 1 binding protein, TGF-beta type I and type II receptors, and endoglin in normal ovary and ovarian neoplasms. Lab Invest (1995) 1.04
Role of NFAT proteins in IL13 gene transcription in mast cells. J Biol Chem (2004) 1.03
Epigenetic biomarkers in esophageal cancer. Cancer Lett (2012) 1.01
The IL1RN promoter rs4251961 correlates with IL-1 receptor antagonist concentrations in human infection and is differentially regulated by GATA-1. J Immunol (2011) 0.99
Independent regulation of short and long forms of latent TGF-beta binding protein (LTBP)-4 in cultured fibroblasts and human tissues. J Cell Physiol (2010) 0.97
Oesophageal cancer survival in Europe: a EUROCARE-4 study. Cancer Epidemiol (2012) 0.96
The role of E2F4 in adipogenesis is independent of its cell cycle regulatory activity. Proc Natl Acad Sci U S A (2003) 0.93
The ECM protein LTBP-2 is a suppressor of esophageal squamous cell carcinoma tumor formation but higher tumor expression associates with poor patient outcome. Int J Cancer (2010) 0.92
DNA microarray analysis of the gene expression profiles of naïve versus activated tumor-specific T cells. Life Sci (2002) 0.89
Expression of transforming growth factors beta 1, beta 2, beta 3 in neuroendocrine tumors of the digestive system. Anticancer Res (1995) 0.85
Downregulation of transforming growth factor β (TGFβ) and latent TGFβ binding protein (LTBP)-4 expression in late stage canine mammary tumours. Vet J (2009) 0.84
Latent transforming growth factor binding protein 4 (LTBP-4) is downregulated in human mammary adenocarcinomas in vitro and in vivo. APMIS (2007) 0.83
LTBP-2 confers pleiotropic suppression and promotes dormancy in a growth factor permissive microenvironment in nasopharyngeal carcinoma. Cancer Lett (2012) 0.83
Disruption of calvarial ossification in E2f4 mutant embryos correlates with increased proliferation and progenitor cell populations. Cell Cycle (2010) 0.82
Evidence for the decreased expression of the latent TGF-beta binding protein and its splice form in human liver tumours. Scand J Gastroenterol (2001) 0.80
Latent transforming growth factor binding protein 4 (LTBP4) is downregulated in mouse and human DCIS and mammary carcinomas. Cell Oncol (Dordr) (2011) 0.79
Induction of human LTBP-3 promoter activity by TGF-beta1 is mediated by Smad3/4 and AP-1 binding elements. Gene (2005) 0.78
FADD prevents RIP3-mediated epithelial cell necrosis and chronic intestinal inflammation. Nature (2011) 3.17
IL-17 producing gammadelta T cells are required for a controlled inflammatory response after bleomycin-induced lung injury. Inflammation (2008) 1.49
Impact of pump flow rate during selective cerebral perfusion on cerebral hemodynamics and metabolism. Ann Thorac Surg (2010) 1.46
Identification of early molecular markers for breast cancer. Mol Cancer (2011) 1.45
In utero and lactational exposures to low doses of polybrominated diphenyl ether-47 alter the reproductive system and thyroid gland of female rat offspring. Environ Health Perspect (2008) 1.12
Angiotensin-(1-7) and the g protein-coupled receptor MAS are key players in renal inflammation. PLoS One (2009) 1.12
Organ-specific distribution of ACE2 mRNA and correlating peptidase activity in rodents. Peptides (2005) 1.11
Disruption of LTBP-4 function reduces TGF-beta activation and enhances BMP-4 signaling in the lung. J Cell Biol (2004) 1.09
Ultrastructural changes observed in rat ovaries following in utero and lactational exposure to low doses of a polybrominated flame retardant. Toxicol Lett (2005) 1.03
A dose response study following in utero and lactational exposure to di-(2-ethylhexyl) phthalate (DEHP): reproductive effects on adult male offspring rats. Toxicology (2006) 1.03
Assessment of in vitro interferon-gamma responses from peripheral blood mononuclear cells of cattle infected with Mycoplasma mycoides ssp. mycoides small colony type. Vet Immunol Immunopathol (2008) 1.02
Inactivation of sestrin 2 induces TGF-beta signaling and partially rescues pulmonary emphysema in a mouse model of COPD. Dis Model Mech (2010) 1.00
Cardiomyocyte-restricted over-expression of C-type natriuretic peptide prevents cardiac hypertrophy induced by myocardial infarction in mice. Eur J Heart Fail (2007) 0.99
A minor role of CD4+ T lymphocytes in the control of a primary infection of cattle with Mycoplasma mycoides subsp. mycoides. Vet Res (2011) 0.98
Severe SMA mice show organ impairment that cannot be rescued by therapy with the HDACi JNJ-26481585. Eur J Hum Genet (2012) 0.96
Accelerated mitochondrial adenosine diphosphate/adenosine triphosphate transport improves hypertension-induced heart disease. Circulation (2007) 0.95
Cardiovascular phenotype of mice lacking all three subtypes of angiotensin II receptors. FASEB J (2008) 0.93
A dose-response study following in utero and lactational exposure to di-(2-ethylhexyl) phthalate (DEHP): reproductive effects on adult female offspring rats. Toxicology (2006) 0.92
A dose-response study following in utero and lactational exposure to di-(2-ethylhexyl) phthalate (DEHP): effects on androgenic status, developmental landmarks and testicular histology in male offspring rats. Toxicology (2006) 0.91
Improved learning and memory in aged mice deficient in amyloid beta-degrading neutral endopeptidase. PLoS One (2009) 0.91
Sildenafil preserves lung endothelial function and prevents pulmonary vascular remodeling in a rat model of diastolic heart failure. Circ Heart Fail (2011) 0.90
Myocardial overexpression of adenine nucleotide translocase 1 ameliorates diabetic cardiomyopathy in mice. Exp Physiol (2008) 0.88
Cardiac phenotype and angiotensin II levels in AT1a, AT1b, and AT2 receptor single, double, and triple knockouts. Cardiovasc Res (2010) 0.88
Antitumor effect of MAb EMD 55900 depends on EGF-R expression and histopathology. Neoplasia (2002) 0.87
Impaired spatial memory and altered dendritic spine morphology in angiotensin II type 2 receptor-deficient mice. J Mol Med (Berl) (2008) 0.87
Latent transforming growth factor binding protein 4 (LTBP-4) is downregulated in human mammary adenocarcinomas in vitro and in vivo. APMIS (2007) 0.83
Repeated episodes of ozone inhalation attenuates airway injury/repair and release of substance P, but not adaptation. Toxicol Appl Pharmacol (2003) 0.82
Excessive hypertension and end-organ damage in a transgenic mouse line carrying the rat angiotensinogen gene. J Cardiovasc Pharmacol (2009) 0.81
Latent transforming growth factor binding protein 4 (LTBP4) is downregulated in mouse and human DCIS and mammary carcinomas. Cell Oncol (Dordr) (2011) 0.79
Evaluation of the use of lower body perfusion at 28°C in aortic arch surgery. Eur J Cardiothorac Surg (2012) 0.79
Rosuvastatin reloading before cardiac surgery with cardiopulmonary bypass. Eur Surg Res (2013) 0.77
Controlled lung reperfusion to reduce pulmonary ischaemia/reperfusion injury after cardiopulmonary bypass in a porcine model. Interact Cardiovasc Thorac Surg (2014) 0.75
Prenatal exposure to the phytoestrogen daidzein resulted in persistent changes in ovarian surface epithelial cell height, folliculogenesis, and estrus phase length in adult Sprague-Dawley rat offspring. J Toxicol Environ Health A (2015) 0.75