PubRank

S M Gasser

Author PubWeight™ 141.61‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Histone H3 and H4 N-termini interact with SIR3 and SIR4 proteins: a molecular model for the formation of heterochromatin in yeast. Cell 1995 7.20
2 The clustering of telomeres and colocalization with Rap1, Sir3, and Sir4 proteins in wild-type Saccharomyces cerevisiae. J Cell Biol 1996 4.72
3 Relocalization of telomeric Ku and SIR proteins in response to DNA strand breaks in yeast. Cell 1999 4.71
4 Chromosome dynamics in the yeast interphase nucleus. Science 2001 4.33
5 Import of proteins into mitochondria. Energy-dependent uptake of precursors by isolated mitochondria. J Biol Chem 1982 4.25
6 Cohabitation of scaffold binding regions with upstream/enhancer elements of three developmentally regulated genes of D. melanogaster. Cell 1986 4.15
7 Metaphase chromosome structure. Involvement of topoisomerase II. J Mol Biol 1986 4.14
8 SIR3 and SIR4 proteins are required for the positioning and integrity of yeast telomeres. Cell 1993 3.77
9 Localization of Sir2p: the nucleolus as a compartment for silent information regulators. EMBO J 1997 3.55
10 Localization of RAP1 and topoisomerase II in nuclei and meiotic chromosomes of yeast. J Cell Biol 1992 3.48
11 Redistribution of silencing proteins from telomeres to the nucleolus is associated with extension of life span in S. cerevisiae. Cell 1997 3.44
12 The yeast Sgs1p helicase acts upstream of Rad53p in the DNA replication checkpoint and colocalizes with Rad53p in S-phase-specific foci. Genes Dev 2000 3.40
13 Mutation of yeast Ku genes disrupts the subnuclear organization of telomeres. Curr Biol 1998 3.13
14 Evidence for silencing compartments within the yeast nucleus: a role for telomere proximity and Sir protein concentration in silencer-mediated repression. Genes Dev 1996 2.85
15 Chromosomal ARS and CEN elements bind specifically to the yeast nuclear scaffold. Cell 1988 2.69
16 Import of proteins into mitochondria. Energy-dependent, two-step processing of the intermembrane space enzyme cytochrome b2 by isolated yeast mitochondria. J Biol Chem 1982 2.46
17 Imported mitochondrial proteins cytochrome b2 and cytochrome c1 are processed in two steps. Proc Natl Acad Sci U S A 1982 2.39
18 RAP-1 factor is necessary for DNA loop formation in vitro at the silent mating type locus HML. Cell 1989 2.32
19 Nuclear compartments and gene regulation. Curr Opin Genet Dev 1999 2.30
20 The carboxy termini of Sir4 and Rap1 affect Sir3 localization: evidence for a multicomponent complex required for yeast telomeric silencing. J Cell Biol 1995 2.26
21 Distortion of the DNA double helix by RAP1 at silencers and multiple telomeric binding sites. J Mol Biol 1993 2.23
22 The positioning and dynamics of origins of replication in the budding yeast nucleus. J Cell Biol 2001 2.05
23 The telobox, a Myb-related telomeric DNA binding motif found in proteins from yeast, plants and human. Nucleic Acids Res 1996 1.98
24 A cytosolic NAD-dependent deacetylase, Hst2p, can modulate nucleolar and telomeric silencing in yeast. EMBO J 2001 1.95
25 Telomeres and the functional architecture of the nucleus. Trends Cell Biol 1993 1.77
26 Casein kinase II phosphorylates the eukaryote-specific C-terminal domain of topoisomerase II in vivo. EMBO J 1992 1.76
27 Chromosome dynamics: the SMC protein family. Curr Opin Genet Dev 1998 1.70
28 A role for the Cdc7 kinase regulatory subunit Dbf4p in the formation of initiation-competent origins of replication. Genes Dev 1999 1.53
29 Import of proteins into mitochondria. In vitro studies on the biogenesis of the outer membrane. J Biol Chem 1983 1.51
30 Cooperation at a distance between silencers and proto-silencers at the yeast HML locus. EMBO J 1996 1.50
31 Long-range silencing and position effects at telomeres and centromeres: parallels and differences. Cell Mol Life Sci 2003 1.48
32 Scaffold attachment of DNA loops in metaphase chromosomes. J Mol Biol 1988 1.48
33 The dynamics of yeast telomeres and silencing proteins through the cell cycle. J Struct Biol 2000 1.46
34 Structural maintenance of chromosomes protein C-terminal domains bind preferentially to DNA with secondary structure. J Biol Chem 1998 1.44
35 Identification and purification of a protein that binds the yeast ARS consensus sequence. Cell 1991 1.41
36 Meiotic behaviours of chromosomes and microtubules in budding yeast: relocalization of centromeres and telomeres during meiotic prophase. Genes Cells 1998 1.38
37 Nuclear organization and transcriptional silencing in yeast. Experientia 1996 1.23
38 MAP kinase signaling induces nuclear reorganization in budding yeast. Curr Biol 2000 1.21
39 Turning telomeres off and on. Curr Opin Cell Biol 2001 1.21
40 Drosophila scaffold-attached regions bind nuclear scaffolds and can function as ARS elements in both budding and fission yeasts. Mol Cell Biol 1990 1.20
41 DNA loops: structural and functional properties of scaffold-attached regions. Mol Microbiol 1992 1.20
42 Functional characterization of the N terminus of Sir3p. Mol Cell Biol 1998 1.17
43 Sif2p interacts with Sir4p amino-terminal domain and antagonizes telomeric silencing in yeast. Curr Biol 1998 1.17
44 Analysis of Sir2p domains required for rDNA and telomeric silencing in Saccharomyces cerevisiae. Genetics 2000 1.17
45 Ku-deficient yeast strains exhibit alternative states of silencing competence. EMBO Rep 2001 1.16
46 Telomeres and telomerase. Genes Dev 1999 1.12
47 Preparation and characterization of yeast nuclear extracts for efficient RNA polymerase B (II)-dependent transcription in vitro. Nucleic Acids Res 1990 1.12
48 RecQ-like helicases: the DNA replication checkpoint connection. J Cell Sci 2000 1.09
49 ORC-dependent and origin-specific initiation of DNA replication at defined foci in isolated yeast nuclei. Genes Dev 1997 1.08
50 Imaging the asymmetrical DNA bend induced by repressor activator protein 1 with scanning tunneling microscopy. J Struct Biol 1995 1.07
51 The nucleolus: nucleolar space for RENT. Curr Biol 1999 1.07
52 RAP1 stimulates single- to double-strand association of yeast telomeric DNA: implications for telomere-telomere interactions. Nucleic Acids Res 1994 1.05
53 Import of polypeptides into isolated yeast mitochondria. Methods Enzymol 1983 1.04
54 Relation of chromosome structure and gene expression. Philos Trans R Soc Lond B Biol Sci 1987 1.04
55 Taz1p and Teb1p, two telobox proteins in Schizosaccharomyces pombe, recognize different telomere-related DNA sequences. Nucleic Acids Res 1999 1.02
56 The positioning of yeast telomeres depends on SIR3, SIR4, and the integrity of the nuclear membrane. Cold Spring Harb Symp Quant Biol 1993 1.01
57 Semi-conservative replication in yeast nuclear extracts requires Dna2 helicase and supercoiled template. J Mol Biol 1998 1.01
58 Nuclear scaffold attachment stimulates, but is not essential for ARS activity in Saccharomyces cerevisiae: analysis of the Drosophila ftz SAR. EMBO J 1990 1.00
59 From snapshots to moving pictures: new perspectives on nuclear organization. Trends Cell Biol 2001 0.99
60 Targeting Sir proteins to sites of action: a general mechanism for regulated repression. Cold Spring Harb Symp Quant Biol 1998 0.98
61 Analysis of etoposide binding to subdomains of human DNA topoisomerase II alpha in the absence of DNA. Biochemistry 2001 0.97
62 Repetitive transgenes in C. elegans accumulate heterochromatic marks and are sequestered at the nuclear envelope in a copy-number- and lamin-dependent manner. Cold Spring Harb Symp Quant Biol 2011 0.97
63 Regulation of topoisomerase II by phosphorylation: a role for casein kinase II. J Cell Sci 1993 0.96
64 New systems for replicating DNA in vitro. Curr Opin Cell Biol 1998 0.96
65 Telomere maintenance and gene repression: a common end? Curr Opin Cell Biol 1994 0.94
66 Analysis of nuclear organization in Saccharomyces cerevisiae. Methods Enzymol 1999 0.94
67 DNA topoisomerase II mutations and resistance to anti-tumor drugs. Bioessays 1995 0.93
68 Casein kinase II copurifies with yeast DNA topoisomerase II and re-activates the dephosphorylated enzyme. J Cell Sci 1993 0.92
69 Chromatin: a sticky silence. Curr Biol 1996 0.90
70 Topoisomerase II forms multimers in vitro: effects of metals, beta-glycerophosphate, and phosphorylation of its C-terminal domain. Mol Cell Biol 1994 0.90
71 Biosynthesis of the ubiquinol-cytochrome c reductase complex in yeast. Characterization of precursor forms of the 44-kDa, 40-kDa and 17-kDa subunits and identification of individual messenger RNAs for these and other imported subunits of the complex. Eur J Biochem 1983 0.88
72 Cyclin B-cdk1 kinase stimulates ORC- and Cdc6-independent steps of semiconservative plasmid replication in yeast nuclear extracts. Mol Cell Biol 1999 0.86
73 Mutations in the C-terminal domain of topoisomerase II affect meiotic function and interaction with the casein kinase 2 beta subunit. Mol Cell Biochem 1999 0.83
74 The yeast protein encoded by PUB1 binds T-rich single stranded DNA. Nucleic Acids Res 1994 0.83
75 Ectopic expression of inactive forms of yeast DNA topoisomerase II confers resistance to the anti-tumour drug, etoposide. Br J Cancer 1996 0.81
76 Assessing import of proteins into mitochondria: an overview. Methods Enzymol 1983 0.81
77 Ribonuclease H(70) is a component of the yeast nuclear scaffold. J Cell Sci 1990 0.80
78 Phosphorylation of the C-terminal domain of yeast topoisomerase II by casein kinase II affects DNA-protein interaction. J Mol Biol 1994 0.79
79 In vitro DNA replication in yeast nuclear extracts. Methods 1999 0.78
80 Functional interaction between the estrogen receptor and CTF1: analysis of the vitellogenin gene B1 promoter in yeast. Mol Endocrinol 1998 0.76
81 The composition and morphology of yeast nuclear scaffolds. J Cell Sci 1990 0.76
82 The regulation of DNA topoisomerase II by casein kinase II. Cell Mol Biol Res 1994 0.76
83 The cytochrome b5 tail anchors and stabilizes subdomains of human DNA topoisomerase II alpha in the cytoplasm of retrovirally infected mammalian cells. Exp Cell Res 1999 0.75
84 Ectopic expression of human topoisomerase IIalpha fragments and etoposide resistance in mammalian cells. Int J Cancer 2000 0.75
85 The nucleosome: from wallflower to Queen of the Ball. Genome Biol 2001 0.75
86 [Telomere-binding activity of Schizosaccharomyces pombe yeasts]. Mol Biol (Mosk) 2000 0.75