Neurofibrillary tangles in nondemented elderly subjects and mild Alzheimer disease.

PubWeight™: 2.02‹?› | Rank: Top 2%

🔗 View Article (PMID 10369312)

Published in Arch Neurol on June 01, 1999

Authors

V Haroutunian1, D P Purohit, D P Perl, D Marin, K Khan, M Lantz, K L Davis, R C Mohs

Author Affiliations

1: Department of Psychiatry, The Mount Sinai School of Medicine, New York, NY, USA. vh@doc.mssm.edu

Articles citing this

Magnetic resonance imaging of the entorhinal cortex and hippocampus in mild cognitive impairment and Alzheimer's disease. J Neurol Neurosurg Psychiatry (2001) 5.12

Overview and findings from the rush Memory and Aging Project. Curr Alzheimer Res (2012) 4.91

Neuropathology of nondemented aging: presumptive evidence for preclinical Alzheimer disease. Neurobiol Aging (2009) 4.36

Correlation of Alzheimer disease neuropathologic changes with cognitive status: a review of the literature. J Neuropathol Exp Neurol (2012) 3.77

Neuropathology and cognitive impairment in Alzheimer disease: a complex but coherent relationship. J Neuropathol Exp Neurol (2009) 2.87

Clinicopathologic correlations in a large Alzheimer disease center autopsy cohort: neuritic plaques and neurofibrillary tangles "do count" when staging disease severity. J Neuropathol Exp Neurol (2007) 2.65

Biomarker modeling of Alzheimer's disease. Neuron (2013) 2.51

Modeling the association between 43 different clinical and pathological variables and the severity of cognitive impairment in a large autopsy cohort of elderly persons. Brain Pathol (2008) 2.44

Role of the neuropathology of Alzheimer disease in dementia in the oldest-old. Arch Neurol (2008) 1.93

Coronary artery disease is associated with Alzheimer disease neuropathology in APOE4 carriers. Neurology (2006) 1.89

Less Alzheimer disease neuropathology in medicated hypertensive than nonhypertensive persons. Neurology (2009) 1.78

Amyloid-first and neurodegeneration-first profiles characterize incident amyloid PET positivity. Neurology (2013) 1.74

Relation of neuropathology to cognition in persons without cognitive impairment. Ann Neurol (2012) 1.65

Early correlation of microglial activation with enhanced tumor necrosis factor-alpha and monocyte chemoattractant protein-1 expression specifically within the entorhinal cortex of triple transgenic Alzheimer's disease mice. J Neuroinflammation (2005) 1.64

Higher atrophy rate of entorhinal cortex than hippocampus in AD. Neurology (2004) 1.64

PGC-1alpha expression decreases in the Alzheimer disease brain as a function of dementia. Arch Neurol (2009) 1.61

Type 2 diabetes is negatively associated with Alzheimer's disease neuropathology. J Gerontol A Biol Sci Med Sci (2005) 1.55

Insulin in combination with other diabetes medication is associated with less Alzheimer neuropathology. Neurology (2008) 1.41

Should development of Alzheimer's disease-specific intravenous immunoglobulin be considered? J Neuroinflammation (2014) 1.41

Uncovering molecular biomarkers that correlate cognitive decline with the changes of hippocampus' gene expression profiles in Alzheimer's disease. PLoS One (2010) 1.41

Biomarkers of Alzheimer's disease. Neurobiol Dis (2008) 1.37

Rates of β-amyloid accumulation are independent of hippocampal neurodegeneration. Neurology (2014) 1.31

Reducing case ascertainment costs in U.S. population studies of Alzheimer's disease, dementia, and cognitive impairment-Part 2. Alzheimers Dement (2011) 1.29

Free radical-mediated damage to brain in Alzheimer's disease and its transgenic mouse models. Free Radic Biol Med (2008) 1.19

Linking hippocampal structure and function to memory performance in an aging population. Arch Neurol (2009) 1.17

Relations between hypometabolism in the posterior association neocortex and hippocampal atrophy in Alzheimer's disease: a PET/MRI correlative study. J Neurol Neurosurg Psychiatry (2001) 1.14

Gain in brain immunity in the oldest-old differentiates cognitively normal from demented individuals. PLoS One (2009) 1.12

Transcriptional vulnerability of brain regions in Alzheimer's disease and dementia. Neurobiol Aging (2007) 1.06

Asymptomatic Alzheimer's disease: a prodrome or a state of resilience? Curr Alzheimer Res (2011) 1.05

Mapping the effect of APOE epsilon4 on gray matter loss in Alzheimer's disease in vivo. Neuroimage (2009) 1.05

Lipocalin 2: novel component of proinflammatory signaling in Alzheimer's disease. FASEB J (2012) 1.03

Preclinical AD Workgroup staging: pathological correlates and potential challenges. Neurobiol Aging (2011) 0.99

DHA improves cognition and prevents dysfunction of entorhinal cortex neurons in 3xTg-AD mice. PLoS One (2011) 0.98

Functional, global and cognitive decline correlates to accumulation of Alzheimer's pathology in MCI and AD. Curr Alzheimer Res (2010) 0.98

Digital pathology and image analysis for robust high-throughput quantitative assessment of Alzheimer disease neuropathologic changes. J Neuropathol Exp Neurol (2012) 0.96

Fleshing out the amyloid cascade hypothesis: the molecular biology of Alzheimer's disease. Dialogues Clin Neurosci (2000) 0.87

Mild cognitive impairment: historical development and summary of research. Dialogues Clin Neurosci (2004) 0.86

Cholesterol and LDL relate to neuritic plaques and to APOE4 presence but not to neurofibrillary tangles. Curr Alzheimer Res (2011) 0.86

Decreased level of olfactory receptors in blood cells following traumatic brain injury and potential association with tauopathy. J Alzheimers Dis (2013) 0.86

Cell cycle checkpoint abnormalities during dementia: A plausible association with the loss of protection against oxidative stress in Alzheimer's disease [corrected]. PLoS One (2013) 0.85

Neuropathological findings processed by artificial neural networks (ANNs) can perfectly distinguish Alzheimer's patients from controls in the Nun Study. BMC Neurol (2007) 0.85

Is there a neuropathology difference between mild cognitive impairment and dementia? Dialogues Clin Neurosci (2009) 0.85

Differential age-related decline in conflict-driven task-set shielding from emotional versus non-emotional distracters. Neuropsychologia (2010) 0.84

Correlation of CT perfusion and CT volumetry in patients with Alzheimer's disease. Pol J Radiol (2010) 0.84

Proliferation in the Alzheimer hippocampus is due to microglia, not astroglia, and occurs at sites of amyloid deposition. Neural Plast (2014) 0.84

Short latency afferent inhibition differs among the subtypes of mild cognitive impairment. J Neural Transm (Vienna) (2011) 0.83

Synaptic protein deficits are associated with dementia irrespective of extreme old age. Neurobiol Aging (2011) 0.83

Parkinson's disease dementia: a diminished role for the Lewy body. Parkinsonism Relat Disord (2009) 0.83

Alzheimer's disease biomarker discovery in symptomatic and asymptomatic patients: experimental approaches and future clinical applications. Exp Gerontol (2009) 0.83

The triggering receptor expressed on myeloid cells 2 (TREM2) is associated with enhanced inflammation, neuropathological lesions and increased risk for Alzheimer's dementia. Alzheimers Dement (2014) 0.82

Increased expression of RXRα in dementia: an early harbinger for the cholesterol dyshomeostasis? Mol Neurodegener (2010) 0.81

Accelerated clinical decline in well-educated patients with frontotemporal lobar degenerations. Eur Arch Psychiatry Clin Neurosci (2009) 0.80

Association of ApoE and LRP mRNA levels with dementia and AD neuropathology. Neurobiol Aging (2011) 0.80

Entorhinal verrucae geometry is coincident and correlates with Alzheimer's lesions: a combined neuropathology and high-resolution ex vivo MRI analysis. Acta Neuropathol (2011) 0.80

Corticosteroids, but not NSAIDs, are associated with less Alzheimer neuropathology. Neurobiol Aging (2011) 0.80

The temporospatial evolution of neuritic plaque-related and independent tauopathies: implications for dementia staging. J Alzheimers Dis (2014) 0.80

Number of children is associated with neuropathology of Alzheimer's disease in women. Neurobiol Aging (2008) 0.79

Genome-wide DNA methylation profiling in the superior temporal gyrus reveals epigenetic signatures associated with Alzheimer's disease. Genome Med (2016) 0.78

Clinical dementia rating performed several years prior to death predicts regional Alzheimer's neuropathology. Dement Geriatr Cogn Disord (2008) 0.78

Sex and gonadal hormones in mouse models of Alzheimer's disease: what is relevant to the human condition? Biol Sex Differ (2012) 0.77

Galantamine-induced improvements in cognitive function are not related to alterations in alpha(4)beta (2) nicotinic receptors in early Alzheimer's disease as measured in vivo by 2-[18F]fluoro-A-85380 PET. Psychopharmacology (Berl) (2008) 0.77

Insulin receptor expression and activity in the brains of nondiabetic sporadic Alzheimer's disease cases. Int J Alzheimers Dis (2012) 0.77

Multimodal Discrimination of Alzheimer's Disease Based on Regional Cortical Atrophy and Hypometabolism. PLoS One (2015) 0.77

The relationship between dopamine receptor D1 and cognitive performance. NPJ Schizophr (2015) 0.75

APOε2 and education in cognitively normal older subjects with high levels of AD pathology at autopsy: findings from the Nun Study. Oncotarget (2015) 0.75

Analysis of binary responses with outcome-specific misclassification probability in genome-wide association studies. Appl Clin Genet (2016) 0.75

Articles by these authors

Current concepts in mild cognitive impairment. Arch Neurol (2001) 18.09

The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part I. Clinical and neuropsychological assessment of Alzheimer's disease. Neurology (1989) 16.83

A new rating scale for Alzheimer's disease. Am J Psychiatry (1984) 15.16

Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse. Nature (1999) 12.95

Peripherally administered antibodies against amyloid beta-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease. Nat Med (2000) 8.89

Genome-wide expression analysis reveals dysregulation of myelination-related genes in chronic schizophrenia. Proc Natl Acad Sci U S A (2001) 6.68

Correlation between elevated levels of amyloid beta-peptide in the brain and cognitive decline. JAMA (2000) 6.55

The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part V. A normative study of the neuropsychological battery. Neurology (1994) 5.81

Amyloid precursor protein processing and A beta42 deposition in a transgenic mouse model of Alzheimer disease. Proc Natl Acad Sci U S A (1997) 4.92

Donepezil improves cognition and global function in Alzheimer disease: a 15-week, double-blind, placebo-controlled study. Donepezil Study Group. Arch Intern Med (1998) 4.43

Pneumocystis carinii pneumonia in the United States. Epidemiologic, diagnostic, and clinical features. Ann Intern Med (1974) 4.10

Practice parameter: management of dementia (an evidence-based review). Report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology (2001) 3.74

Neuropathological evidence of graft survival and striatal reinnervation after the transplantation of fetal mesencephalic tissue in a patient with Parkinson's disease. N Engl J Med (1995) 3.64

Tangle and neuron numbers, but not amyloid load, predict cognitive status in Alzheimer's disease. Neurology (2003) 3.62

CNTNAP2 gene dosage variation is associated with schizophrenia and epilepsy. Mol Psychiatry (2007) 3.44

Accelerated bone mineral loss in HIV-infected patients receiving potent antiretroviral therapy. AIDS (2000) 3.39

Cholinergic markers in elderly patients with early signs of Alzheimer disease. JAMA (1999) 3.22

Regional distribution of neuritic plaques in the nondemented elderly and subjects with very mild Alzheimer disease. Arch Neurol (1998) 3.20

A neuronal morphologic type unique to humans and great apes. Proc Natl Acad Sci U S A (1999) 2.81

A randomized controlled trial of prednisone in Alzheimer's disease. Alzheimer's Disease Cooperative Study. Neurology (2000) 2.76

National Institute of Mental Health Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE): Alzheimer disease trial methodology. Am J Geriatr Psychiatry (2001) 2.74

Acid sphingomyelinase deficient mice: a model of types A and B Niemann-Pick disease. Nat Genet (1995) 2.66

Evidence for a susceptibility gene for autism on chromosome 2 and for genetic heterogeneity. Am J Hum Genet (2001) 2.51

Consortium to establish a registry for Alzheimer's disease (CERAD) clinical and neuropsychological assessment of Alzheimer's disease. Psychopharmacol Bull (1988) 2.50

The presence of a BCR-ABL mutant allele in CML does not always explain clinical resistance to imatinib. Leukemia (2006) 2.49

Alzheimer's disease: X-ray spectrometric evidence of aluminum accumulation in neurofibrillary tangle-bearing neurons. Science (1980) 2.45

A longitudinal study of Alzheimer's disease: measurement, rate, and predictors of cognitive deterioration. Am J Psychiatry (1994) 2.41

Tei-index in patients with mild-to-moderate congestive heart failure. Eur Heart J (2000) 2.37

Detection and staging of dementia in Alzheimer's disease. Use of the neuropsychological measures developed for the Consortium to Establish a Registry for Alzheimer's Disease. Arch Neurol (1992) 2.19

The evolution of diagnosis in early Parkinson disease. Parkinson Study Group. Arch Neurol (2000) 2.08

The pathology of Legionnaires' disease. Fourteen fatal cases from the 1977 outbreak in Vermont. Arch Pathol Lab Med (1978) 2.06

Rising mortality from motoneuron disease in the USA, 1962-84. Lancet (1989) 2.05

Ionotropic glutamate receptor binding and subunit mRNA expression in thalamic nuclei in schizophrenia. Am J Psychiatry (2000) 1.93

Distribution, propagation, and coordination of contractile activity in lymphatics. Am J Physiol (1993) 1.92

Molecular genetics and nomenclature of proteases of Porphyromonas gingivalis. J Periodontal Res (1999) 1.90

Coronary artery disease is associated with Alzheimer disease neuropathology in APOE4 carriers. Neurology (2006) 1.89

Evidence of neuronal oxidative damage in Alzheimer's disease. Am J Pathol (1996) 1.87

Development and validation of a questionnaire to evaluate the effectiveness of evidence-based practice teaching. Med Educ (2001) 1.87

Patterns of risk in first-degree relatives of patients with Alzheimer's disease. Arch Gen Psychiatry (1994) 1.84

The Alzheimer's disease assessment scale: an instrument for assessing treatment efficacy. Psychopharmacol Bull (1983) 1.81

Reliability of the family history method in genetic studies of Alzheimer's disease and related dementias. Am J Psychiatry (1986) 1.80

Serotonergic studies in patients with affective and personality disorders. Correlates with suicidal and impulsive aggressive behavior. Arch Gen Psychiatry (1989) 1.79

Less Alzheimer disease neuropathology in medicated hypertensive than nonhypertensive persons. Neurology (2009) 1.78

A psychobiological perspective on the personality disorders. Am J Psychiatry (1991) 1.76

Serum lysozyme in pulmonary tuberculosis. Am J Med Sci (1973) 1.75

Genome scan of schizophrenia. Am J Psychiatry (1998) 1.74

Long-term metabolic, endocrine, and neuropsychological outcome of hematopoietic cell transplantation for Wolman disease. Bone Marrow Transplant (2008) 1.71

Neocortical neurofibrillary tangles correlate with dementia severity in Alzheimer's disease. Arch Neurol (1995) 1.69

Collagenolytic activity associated with Bacteroides species and Actinobacillus actinomycetemcomitans. J Periodontal Res (1982) 1.69

Dissociation of neuropathology from severity of dementia in late-onset Alzheimer disease. Neurology (2006) 1.68

hOCT1 transcript levels and single nucleotide polymorphisms as predictive factors for response to imatinib in chronic myeloid leukemia. Leukemia (2010) 1.67

Intraneuronal aluminum accumulation in amyotrophic lateral sclerosis and Parkinsonism-dementia of Guam. Science (1982) 1.63

Neuropeptide abnormalities in patients with early Alzheimer disease. Arch Gen Psychiatry (1999) 1.62

Guanfacine treatment of cognitive impairment in schizophrenia. Neuropsychopharmacology (2001) 1.61

Symptoms, cognitive functioning, and adaptive skills in geriatric patients with lifelong schizophrenia: a comparison across treatment sites. Am J Psychiatry (1998) 1.60

Nonsurgical treatment of stress urinary incontinence (SUI): grading of evidence in systematic reviews. BJOG (2008) 1.60

Manganese intoxication in the rhesus monkey: a clinical, imaging, pathologic, and biochemical study. Neurology (1996) 1.60

Severe decompression retinopathy after medical treatment of acute primary angle closure. Br J Ophthalmol (2007) 1.59

Isolation and characterization of a tumor necrosis factor binding protein from urine. Eur J Haematol (1989) 1.57

Optical coherence tomographic pattern may predict visual outcome after intravitreal triamcinolone for diabetic macular edema. Ophthalmology (2007) 1.56

Two decades of increasing mortality from Parkinson's disease among the US elderly. Arch Neurol (1990) 1.56

Nilotinib is active in chronic and accelerated phase chronic myeloid leukemia following failure of imatinib and dasatinib therapy. Leukemia (2010) 1.54

Investigation of a fatality from nonoccupational aluminum phosphide exposure: measurement of aluminum in tissue and body fluids as a marker of exposure. J Lab Clin Med (1993) 1.53

Response to donor lymphocyte infusions for chronic myeloid leukemia is dose-dependent: the importance of escalating the cell dose to maximize therapeutic efficacy. Leukemia (2007) 1.53

Neuropeptide deficits in schizophrenia vs. Alzheimer's disease cerebral cortex. Biol Psychiatry (1996) 1.52

Introduction of portable computed tomography scanners, in the treatment of acute stroke patients via telemedicine in remote communities. Int J Stroke (2010) 1.51

Eye tracking, attention, and schizotypal symptoms in nonpsychotic relatives of patients with schizophrenia. Arch Gen Psychiatry (1997) 1.51

Neurological manifestations of hereditary hemorrhagic telangiectasia (Rendu-Osler-Weber disease): report of 2 cases and review of the literature. Ann Neurol (1978) 1.50

Accumulation of phosphorylated neurofilaments in anterior horn motoneurons of amyotrophic lateral sclerosis patients. J Neuropathol Exp Neurol (1988) 1.49

The development and piloting of a capacity assessment tool. J Clin Ethics (2001) 1.48

The longitudinal stability of cognitive impairment in schizophrenia. Mini-mental state scores at one- and two-year follow-ups in geriatric in-patients. Br J Psychiatry (1995) 1.46

Protein nitration in Parkinson's disease. J Neuropathol Exp Neurol (1998) 1.45