Published in Hum Mol Genet on July 01, 1999
Joint genetic susceptibility to type 1 diabetes and autoimmune thyroiditis: from epidemiology to mechanisms. Endocr Rev (2008) 1.66
Interferon alpha treatment and thyroid dysfunction. Endocrinol Metab Clin North Am (2007) 1.63
Common and unique susceptibility loci in Graves and Hashimoto diseases: results of whole-genome screening in a data set of 102 multiplex families. Am J Hum Genet (2003) 1.59
HCV E2 protein binds directly to thyroid cells and induces IL-8 production: a new mechanism for HCV induced thyroid autoimmunity. J Autoimmun (2008) 1.35
Diagnostic tools in Rhinology EAACI position paper. Clin Transl Allergy (2011) 1.27
An immune defect causing dominant chronic mucocutaneous candidiasis and thyroid disease maps to chromosome 2p in a single family. Am J Hum Genet (2001) 1.18
Interferon induced thyroiditis. Best Pract Res Clin Endocrinol Metab (2009) 1.04
Thyroglobulin as an autoantigen: what can we learn about immunopathogenicity from the correlation of antigenic properties with protein structure? Immunology (2004) 1.03
Immunogenetics of Hashimoto's thyroiditis. J Autoimmune Dis (2005) 1.02
The interferon induced with helicase domain 1 A946T polymorphism is not associated with rheumatoid arthritis. Arthritis Res Ther (2007) 0.99
'Linkage analysis of thyroid antibody production: evidence for shared susceptibility to clinical autoimmune thyroid disease. J Clin Endocrinol Metab (2008) 0.97
GWAS in autoimmune thyroid disease: redefining our understanding of pathogenesis. Nat Rev Endocrinol (2013) 0.96
Genetic variants in T helper cell type 1, 2 and 3 pathways and gastric cancer risk in a Polish population. Jpn J Clin Oncol (2008) 0.92
Cytotoxic T lymphocyte associated antigen-4 gene polymorphisms confer susceptibility to primary biliary cirrhosis and autoimmune hepatitis in Chinese population. World J Gastroenterol (2004) 0.92
Genetic profiling in Graves' disease: further evidence for lack of a distinct genetic contribution to Graves' ophthalmopathy. Thyroid (2012) 0.89
Gatekeepers of intestinal inflammation. Inflamm Res (2010) 0.85
Further evidence for a susceptibility locus on chromosome 20q13.11 in families with dominant transmission of Graves disease. Am J Hum Genet (1999) 0.85
Immunogenetic mechanisms leading to thyroid autoimmunity: recent advances in identifying susceptibility genes and regions. Curr Genomics (2011) 0.85
Unravelling the genetic complexity of autoimmune thyroid disease: HLA, CTLA-4 and beyond. Clin Exp Immunol (2004) 0.84
Evidence for a new Graves disease susceptibility locus at chromosome 18q21. Am J Hum Genet (2000) 0.83
Associations of CTLA4 Gene Polymorphisms with Graves' Ophthalmopathy: A Meta-Analysis. Int J Genomics (2014) 0.83
Association of CTLA4 gene polymorphism in Iranian patients with ankylosing spondylitis. J Clin Immunol (2009) 0.82
The genetic basis of graves' disease. Curr Genomics (2011) 0.81
Association between STAT4 gene polymorphisms and autoimmune thyroid diseases in a Chinese population. Int J Mol Sci (2014) 0.80
Association between IL-21 gene rs907715 polymorphisms and Graves' disease in a Southern Chinese population. Exp Ther Med (2014) 0.79
A Study on the Level of T(3), T(4), TSH and the Association of A/G Polymorphism with CTLA-4 Gene in Graves' Hyperthyroidism among South Indian Population. Indian J Clin Biochem (2010) 0.79
Exon 33 T/T genotype of the thyroglobulin gene is a susceptibility gene for Graves' disease in Taiwanese and exon 12 C/C genotype protects against it. Clin Exp Med (2008) 0.79
Candidate gene regions and genetic heterogeneity in gluten sensitivity. Gut (2001) 0.78
Association between CTLA-4 rs231775 polymorphism and risk of colorectal cancer: a meta analysis. Int J Clin Exp Med (2015) 0.76
CTLA4 exon 1 polymorphism, rheumatoid arthritis and autoimmune endocrinopathy. Clin Rheumatol (2004) 0.75
Differences in Gene-Gene Interactions in Graves' Disease Patients Stratified by Age of Onset. PLoS One (2016) 0.75
Tremelimumab-Induced Graves Hyperthyroidism. Eur Thyroid J (2017) 0.75
Transposable elements associated with constitutive expression of yeast alcohol dehydrogenase II. Cell (1981) 5.17
Exposure to farming in early life and development of asthma and allergy: a cross-sectional survey. Lancet (2001) 4.70
A new highly penetrant form of obesity due to deletions on chromosome 16p11.2. Nature (2010) 4.52
Vegetative bacteriophage lambda-DNA. I. Infectivity in a spheroplast assay. J Mol Biol (1967) 4.33
A common molecular basis for three inherited kidney stone diseases. Nature (1996) 4.26
Sequence homology of the yeast regulatory protein ADR1 with Xenopus transcription factor TFIIIA. Nature (1986) 4.12
Hypothyroidism. Lancet (1997) 4.00
A genomewide scan for loci predisposing to type 2 diabetes in a U.K. population (the Diabetes UK Warren 2 Repository): analysis of 573 pedigrees provides independent replication of a susceptibility locus on chromosome 1q. Am J Hum Genet (2001) 3.26
A familial syndrome of hypocalcemia with hypercalciuria due to mutations in the calcium-sensing receptor. N Engl J Med (1996) 3.20
Clinical findings of West Nile virus infection in hospitalized patients, New York and New Jersey, 2000. Emerg Infect Dis (2001) 2.97
Excess mortality in a population with diabetes and the impact of material deprivation: longitudinal, population based study. BMJ (2001) 2.91
Nucleotide sequence of the yeast alcohol dehydrogenase II gene. J Biol Chem (1983) 2.82
Urban traffic and pollutant exposure related to respiratory outcomes and atopy in a large sample of children. Eur Respir J (2003) 2.79
Zinc-dependent structure of a single-finger domain of yeast ADR1. Science (1988) 2.76
Vegetative bacteriophage lambda-DNA. II. Physical characterization and replication. J Mol Biol (1967) 2.74
Characterization of a regulatory region upstream of the ADR2 locus of S. cerevisiae. Nature (1982) 2.54
DNA sequences of two yeast promoter-up mutants. Nature (1983) 2.50
Translational regulation of expression of the bacteriophage T4 lysozyme gene. Nucleic Acids Res (1986) 2.45
The codon 620 tryptophan allele of the lymphoid tyrosine phosphatase (LYP) gene is a major determinant of Graves' disease. J Clin Endocrinol Metab (2004) 2.44
Isolation and characterization of the positive regulatory gene ADR1 from Saccharomyces cerevisiae. Mol Cell Biol (1983) 2.43
The short Synacthen and insulin stress tests in the assessment of the hypothalamic-pituitary-adrenal axis. Clin Endocrinol (Oxf) (1996) 2.41
Treatment of hypothyroidism: a reappraisal of thyroxine therapy. Br Med J (1973) 2.30
Prevalence and projections of diabetes and pre-diabetes in adults in Sri Lanka--Sri Lanka Diabetes, Cardiovascular Study (SLDCS). Diabet Med (2008) 2.26
Ablative radioiodine therapy for hyperthyroidism: long term follow up study. Br Med J (Clin Res Ed) (1984) 2.22
TCF7L2: the biggest story in diabetes genetics since HLA? Diabetologia (2007) 2.22
Common nonsynonymous substitutions in SLCO1B1 predispose to statin intolerance in routinely treated individuals with type 2 diabetes: a go-DARTS study. Clin Pharmacol Ther (2010) 2.22
Occult thyrotoxicosis: a correctable cause of "idiopathic" atrial fibrillation. Am J Cardiol (1979) 2.20
A positive regulatory gene is required for accumulation of the functional messenger RNA for the glucose-repressible alcohol dehydrogenase from Saccharomyces cerevisiae. J Mol Biol (1981) 2.19
Parameters associated with persistent airflow obstruction in chronic severe asthma. Eur Respir J (2004) 2.18
Two zinc fingers of a yeast regulatory protein shown by genetic evidence to be essential for its function. Nature (1987) 2.11
Characterization of transposable element-associated mutations that alter yeast alcohol dehydrogenase II expression. Mol Cell Biol (1983) 2.09
Serum S-100beta protein is a potential biochemical marker for cerebral oedema complicating severe diabetic ketoacidosis. Diabet Med (2000) 2.04
Isolation of the structural gene for alcohol dehydrogenase by genetic complementation in yeast. Nature (1980) 2.03
Management of the unexpected result: compensated hypothyroidism. Postgrad Med J (1998) 2.02
Parent-offspring trios: a resource to facilitate the identification of type 2 diabetes genes. Diabetes (1999) 1.97
The yeast regulatory protein ADR1 binds in a zinc-dependent manner to the upstream activating sequence of ADH2. Mol Cell Biol (1988) 1.96
Linkage and association of insulin gene VNTR regulatory polymorphism with polycystic ovary syndrome. Lancet (1997) 1.91
Isolation and DNA sequence of ADH3, a nuclear gene encoding the mitochondrial isozyme of alcohol dehydrogenase in Saccharomyces cerevisiae. Mol Cell Biol (1985) 1.88
The development of ischemic heart disease in relation to autoimmune thyroid disease in a 20-year follow-up study of an English community. Thyroid (1996) 1.86
Reliability of the Washington University Road Test. A performance-based assessment for drivers with dementia of the Alzheimer type. Arch Neurol (1997) 1.84
The genetic and epigenetic basis of type 2 diabetes and obesity. Clin Pharmacol Ther (2012) 1.84
A gene variant near ATM is significantly associated with metformin treatment response in type 2 diabetes: a replication and meta-analysis of five cohorts. Diabetologia (2012) 1.83
Association between polymorphisms in serine protease inhibitor, kazal type 5 and asthma phenotypes in a large German population sample. Clin Exp Allergy (2004) 1.80
Deletion analysis identifies a region, upstream of the ADH2 gene of Saccharomyces cerevisiae, which is required for ADR1-mediated derepression. Mol Cell Biol (1985) 1.79
Farnesyl transferase inhibitors block the farnesylation of CENP-E and CENP-F and alter the association of CENP-E with the microtubules. J Biol Chem (2000) 1.78
Unrecognized hypocalcaemia diagnosed 36 years after thyroidectomy. J R Soc Med (1995) 1.77
Obesity and polycystic ovary syndrome. Clin Endocrinol (Oxf) (2006) 1.76
Abnormal left ventricular function in hyperthyroidism: evidence for a possible reversible cardiomyopathy. N Engl J Med (1982) 1.74
mRNA levels for the fermentative alcohol dehydrogenase of Saccharomyces cerevisiae decrease upon growth on a nonfermentable carbon source. J Biol Chem (1983) 1.74
An association between the CTLA4 exon 1 polymorphism and early rheumatoid arthritis with autoimmune endocrinopathies. Rheumatology (Oxford) (2002) 1.74
Alanine scanning site-directed mutagenesis of the zinc fingers of transcription factor ADR1: residues that contact DNA and that transactivate. Proc Natl Acad Sci U S A (1991) 1.73
A specific IgG in Graves' ophthalmopathy and its relation to retro-orbital and thyroid autoimmunity. Br Med J (Clin Res Ed) (1984) 1.72
Effects of growth-hormone release-inhibiting hormone on circulating glucagon, insulin, and growth hormone in normal, diabetic, acromegalic, and hypopituitary patients. Lancet (1974) 1.71
Cytotoxic T lymphocyte antigen-4 (CTLA-4) gene polymorphism confers susceptibility to thyroid associated orbitopathy. Lancet (1999) 1.70
An assessment of plasma TSH radioimmunoassay and of the TSH stimulation test in the diagnosis of 100 consecutive patients with suspected hypothyroidism. Clin Endocrinol (Oxf) (1973) 1.70
Characterisation of human thyroid epithelial cells immortalised in vitro by simian virus 40 DNA transfection. Br J Cancer (1989) 1.68
Women with a history of gestational diabetes of European and South Asian origin are shorter than women with normal glucose tolerance in pregnancy. Diabet Med (2000) 1.67
Analysis of variation in PF83, an erythrocytic merozoite vaccine candidate antigen of Plasmodium falciparum. Mol Biochem Parasitol (1991) 1.65
FTO gene variants are strongly associated with type 2 diabetes in South Asian Indians. Diabetologia (2008) 1.65
A new strategy for thyroid function testing. Lancet (1985) 1.63
Global microRNA expression profiles in insulin target tissues in a spontaneous rat model of type 2 diabetes. Diabetologia (2010) 1.60
Expression and characterization of inactivating and activating mutations in the human Ca2+o-sensing receptor. J Biol Chem (1996) 1.59
Molecular analysis of the PDS gene in Pendred syndrome. Hum Mol Genet (1998) 1.58
Consensus statement on the diagnosis, treatment and follow-up of patients with primary adrenal insufficiency. J Intern Med (2013) 1.57
Diffuse sclerosing papillary carcinoma of thyroid: a wolf in sheep's clothing. Clin Endocrinol (Oxf) (1989) 1.56
Effect of RNase III on efficiency of translation of bacteriophage T7 lysozyme mRNA. J Virol (1978) 1.56
Carbon source dependence of transposable element-associated gene activation in Saccharomyces cerevisiae. Mol Cell Biol (1984) 1.56
Exome sequencing-driven discovery of coding polymorphisms associated with common metabolic phenotypes. Diabetologia (2012) 1.55
Heritability estimates for beta cell function and features of the insulin resistance syndrome in UK families with an increased susceptibility to type 2 diabetes. Diabetologia (2004) 1.54
A case of euglycaemic diabetic ketoacidosis in pregnancy. Diabet Med (2001) 1.54
Purification and properties of intracellular lamba DNA rings. J Mol Biol (1968) 1.53
The yeast ADR6 gene encodes homopolymeric amino acid sequences and a potential metal-binding domain. Nucleic Acids Res (1988) 1.53
Radiological malformations of the ear in Pendred syndrome. Clin Radiol (1998) 1.52
T4 late transcripts are initiated near a conserved DNA sequence. Nature (1982) 1.49
Brief report: autosomal dominant familial hypoparathyroidism, sensorineural deafness, and renal dysplasia. N Engl J Med (1992) 1.49
Glutathione S transferase deficiency and passive smoking increase childhood asthma. Thorax (2004) 1.49
Regulation of expression and activity of the yeast transcription factor ADR1. Mol Cell Biol (1988) 1.47
The clinical utility of a non-isotopic two-step assay (DELFIA) and an analogue radioimmunoassay (SimulTRAC) for free thyroxine compared. Ann Clin Biochem (1991) 1.47
A comparison of plasma TSH levels in patients with diffuse and nodular non-toxic goiter. J Clin Endocrinol Metab (1976) 1.47
Pendred syndrome--100 years of underascertainment? QJM (1997) 1.45
Assessment of in vitro thyroid function tests in 100 consecutive patients referred to a thyroid clinic. Clin Endocrinol (Oxf) (1973) 1.45
Different hepatic responses to thyroxine replacement in spontaneous and 131I-induced primary hypothyroidism. Clin Endocrinol (Oxf) (1989) 1.45
Effects of exercise on lymphocytes and cytokines. Br J Sports Med (2000) 1.45
Two monomers of yeast transcription factor ADR1 bind a palindromic sequence symmetrically to activate ADH2 expression. Mol Cell Biol (1991) 1.43
Regulation of synthesis of bacteriophage T7 lysozyme mRNA. Virology (1973) 1.43
cAMP-dependent phosphorylation and inactivation of yeast transcription factor ADR1 does not affect DNA binding. Proc Natl Acad Sci U S A (1990) 1.43
Sexual dimorphism in 11 beta hydroxysteroid dehydrogenase activity and its relation to fat distribution and insulin sensitivity; a study in hypopituitary subjects. Clin Endocrinol (Oxf) (1998) 1.40
Heterozygous MDR3 missense mutation associated with intrahepatic cholestasis of pregnancy: evidence for a defect in protein trafficking. Hum Mol Genet (2000) 1.39
A procedure to overcome interferences caused by the adulterant "Klear" in the GC-MS analysis of 11-nor-delta9-THC-9-COOH. J Anal Toxicol (1997) 1.39
Biliary colic on abrupt withdrawal of octreotide. Lancet (1991) 1.38
Isolated aldosterone deficiency in a patient with autoimmune adrenalitis. Am J Med (1991) 1.37
Mechanisms of drug-induced lupus. II. T cells overexpressing lymphocyte function-associated antigen 1 become autoreactive and cause a lupuslike disease in syngeneic mice. J Clin Invest (1996) 1.36
Weight change with liraglutide and comparator therapies: an analysis of seven phase 3 trials from the liraglutide diabetes development programme. Diabetes Obes Metab (2012) 1.34
Subtle metabolic and liver gene transcriptional changes underlie diet-induced fatty liver susceptibility in insulin-resistant mice. Diabetologia (2007) 1.34
Transcription of the ADH2 gene in Saccharomyces cerevisiae is limited by positive factors that bind competitively to its intact promoter region on multicopy plasmids. Mol Cell Biol (1987) 1.33