Tremelimumab-Induced Graves Hyperthyroidism.

PubWeight™: 0.75‹?›

🔗 View Article (PMID 28785544)

Published in Eur Thyroid J on March 14, 2017

Authors

Earn H Gan1, Anna L Mitchell1, Ruth Plummer1, Simon Pearce1, Petros Perros1

Author Affiliations

1: Institute of Genetic Medicine, International Centre for Life, Newcastle upon Tyne, United Kingdom.

Articles cited by this

Improved survival with ipilimumab in patients with metastatic melanoma. N Engl J Med (2010) 67.34

Ipilimumab plus dacarbazine for previously untreated metastatic melanoma. N Engl J Med (2011) 26.90

Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammation. J Exp Med (2000) 16.09

Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease. Nature (2003) 13.00

CTLA-4 can function as a negative regulator of T cell activation. Immunity (1994) 9.80

Shared and distinct genetic variants in type 1 diabetes and celiac disease. N Engl J Med (2008) 7.66

Mechanisms of immune evasion by tumors. Adv Immunol (2006) 5.34

A new member of the immunoglobulin superfamily--CTLA-4. Nature (1987) 5.10

Antitumor activity in melanoma and anti-self responses in a phase I trial with the anti-cytotoxic T lymphocyte-associated antigen 4 monoclonal antibody CP-675,206. J Clin Oncol (2005) 4.77

Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci. PLoS Genet (2011) 3.68

Blockade of CTLA-4 on CD4+CD25+ regulatory T cells abrogates their function in vivo. J Immunol (2006) 3.42

The B7 family of ligands and its receptors: new pathways for costimulation and inhibition of immune responses. Annu Rev Immunol (2001) 3.41

Tremelimumab for patients with chemotherapy-resistant advanced malignant mesothelioma: an open-label, single-arm, phase 2 trial. Lancet Oncol (2013) 3.28

Cancer immunosuppression and autoimmune disease: beyond immunosuppressive networks for tumour immunity. Immunology (2006) 1.54

Thyroid autoimmunity and ophthalmopathy related to melanoma biological therapy. Eur J Endocrinol (2010) 1.33

Endocrine-related adverse events following ipilimumab in patients with advanced melanoma: a comprehensive retrospective review from a single institution. Endocr Relat Cancer (2014) 1.32

Alemtuzumab treatment of multiple sclerosis: long-term safety and efficacy. J Neurol Neurosurg Psychiatry (2014) 1.21

The cytotoxic T lymphocyte antigen-4 is a major Graves' disease locus. Hum Mol Genet (1999) 1.19

Immune related adverse events associated with anti-CTLA-4 antibodies: systematic review and meta-analysis. BMC Med (2015) 1.18

Association of the T-cell regulatory gene CTLA4 with Graves' disease and autoimmune thyroid disease in the Japanese. J Hum Genet (2004) 1.00

CTLA-4 is expressed by human monocyte-derived dendritic cells and regulates their functions. Hum Immunol (2010) 0.98

Endocrinological side-effects of immune checkpoint inhibitors. Curr Opin Oncol (2016) 0.96

Alemtuzumab-related thyroid dysfunction in a phase 2 trial of patients with relapsing-remitting multiple sclerosis. J Clin Endocrinol Metab (2013) 0.96

Thyroid-like ophthalmopathy in a euthyroid patient receiving Ipilimumab. Orbit (2014) 0.95

Phase I trial of tremelimumab in combination with short-term androgen deprivation in patients with PSA-recurrent prostate cancer. Cancer Immunol Immunother (2011) 0.93

Phase I study of tremelimumab (CP-675 206) plus PF-3512676 (CPG 7909) in patients with melanoma or advanced solid tumours. Br J Cancer (2013) 0.89

Variation in the CTLA4 3'UTR has phenotypic consequences for autoreactive T cells and associates with genetic risk for type 1 diabetes. Genes Immun (2015) 0.81

Molecular Pathways: Immune Checkpoint Antibodies and their Toxicities. Clin Cancer Res (2016) 0.80

Treatment of Ipilimumab Induced Graves' Disease in a Patient with Metastatic Melanoma. Case Rep Endocrinol (2016) 0.75