Published in Science on June 18, 1999
Estimate of the mutation rate per nucleotide in humans. Genetics (2000) 15.08
On the sequencing of the human genome. Proc Natl Acad Sci U S A (2002) 5.59
Hantavirus outbreak yields to PCR. Science (1993) 9.80
Dispute slows paper on "remarkable" vaccine. Science (1995) 5.83
Gene therapy death prompts review of adenovirus vector. Science (1999) 4.33
When does intellectual passion become conflict of interest? Science (1992) 3.30
Whose genome is it, anyway? Science (1996) 3.29
Clinical trials. Planned Ritalin trial for tots heads into uncharted waters. Science (2000) 2.70
New Zealand's leap into gene therapy. Science (1996) 2.67
Lyme disease. NIH gears up to test a hotly disputed theory. Science (1995) 2.65
Allen Roses: from 'street fighter' to corporate insider. Science (1998) 2.37
Bermuda rules: community spirit, with teeth. Science (2001) 2.36
Drug firms to create public database of genetic mutations. Science (1999) 2.14
Despite anxiety, NIH begins merging neuroscience panels. Science (1996) 2.04
Startling revelations in UC-Genentech battle. Science (1999) 2.04
Alternative medicine. Bastions of tradition adapt to alternative medicine. Science (2000) 2.04
Supreme Court to weigh science. Science (1993) 2.03
NIH panel urges overhaul of the rating system for grants. Science (1996) 2.01
Policy on DNA research troubles tissue bankers. Science (1996) 2.00
Shall we operate? Preoperative assessment in elderly cancer patients (PACE) can help. A SIOG surgical task force prospective study. Crit Rev Oncol Hematol (2007) 1.98
Epidemiology. Search for a killer: focus shifts from fat to hormones. Science (1993) 1.77
Scientific misconduct. How prevalent is fraud? That's a million-dollar question. Science (2000) 1.73
Neurotoxicity among pesticide applicators exposed to organophosphates. Occup Environ Med (1995) 1.71
Too radical for NIH? Try DARPA. Science (1997) 1.68
Oral antibiotics with early hospital discharge compared with in-patient intravenous antibiotics for low-risk febrile neutropenia in patients with cancer: a prospective randomised controlled single centre study. Br J Cancer (2003) 1.62
Mood changes and "on-off" phenomena in Parkinson's disease. Mov Disord (1990) 1.59
Snipping away at genome patenting. Science (1997) 1.57
Varmus proposes to scrap the RAC. Science (1996) 1.57
Data sharing: a declining ethic? Science (1990) 1.56
The mouse that prompted a roar. Science (1997) 1.55
Congenital defects and electric bed heating in New York State: a register-based case-control study. Am J Epidemiol (1992) 1.46
Toxicology goes molecular. Science (1993) 1.46
Less hype, more biology needed for gene therapy. Science (1995) 1.45
A is for apple, Alar, and ... alarmist? Science (1991) 1.44
The human gene hunt scales up. Science (1996) 1.43
Varmus orders up a review of the science of gene therapy. Science (1995) 1.42
Fallout from Pacific tests reaches Congress. Science (1989) 1.42
Six-month success of intracoronary stenting for anomalous coronary arteries associated with myocardial ischemia. Am J Cardiol (2000) 1.42
The role of the practice nurse in the management of depression in general practice: treatment adherence to antidepressant medication. Psychol Med (1993) 1.41
A clash over standards for scientific records. Science (1990) 1.40
A bitter battle over insulin gene. Science (1997) 1.40
Is data-hoarding slowing the assault on pathogens? Science (1997) 1.40
Academy panel raises radiation risk estimate. Science (1990) 1.40
Medicine. Fast technology drives new world of newborn screening. Science (2001) 1.40
Trial set to focus on peer review. Science (1996) 1.40
Rules on embryo research due out. Science (1994) 1.39
NIMH: caught in the line of fire without a general. Science (1995) 1.39
Paleoanthropology gets physical. Science (1990) 1.39
Financial conflict. Universities puncture modest regulatory trial balloon. Science (2001) 1.39
NIH told to reconsider crime meeting. Science (1993) 1.39
Anxiety hits mental health institute. Science (1994) 1.39
Artificial heart: the beat goes on. Science (1991) 1.38
Panel urges cloning ethics board. Science (1997) 1.38
Management overhaul at Johns Hopkins. Science (1995) 1.38
Human Genome Project. Sequencers endorse plan for a draft in 1 year. Science (1999) 1.36
Gene therapy on trial. Science (2000) 1.34
NIH launches the final push to sequence the genome. Science (1996) 1.27
Topography, extent, and clinical relevance of neurochemical deficits in dementia of Lewy body type, Parkinson's disease, and Alzheimer's disease. Ann N Y Acad Sci (1991) 1.24
Varmus circulates proposal for NIH-backed online venture. Science (1999) 1.22
Human genome. Rival genome sequencers celebrate a milestone together. Science (2000) 1.20
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Effects of continued androgen-deprivation therapy and other prognostic factors on response and survival in phase II chemotherapy trials for hormone-refractory prostate cancer: a Southwest Oncology Group report. J Clin Oncol (1994) 1.16
Hubris and the human genome. Science (1998) 1.16
Bioethics. Cloning announcement sparks debate and scientific skepticism. Science (2001) 1.13
NIH's online publishing venture ready for launch. Science (1999) 1.12
DNA sequencing. Genome teams adjust to shotgun marriage. Science (2001) 1.12
Tobacco industry does slow burn over EPA adviser. Science (1990) 1.11
A new ultrasensitive assay for quantitation of HIV-1 RNA in plasma. J Virol Methods (2001) 1.10
Gene therapy's growing pains. Science (1995) 1.09
Medline searches turn up cases of suspected plagiarism. Science (1998) 1.07
Genome sequencing. Celera assembles mouse genome; public labs plan new strategy. Science (2001) 1.05
Fraud strikes top genome lab. Science (1996) 1.05
Malaria. A renewed assault on an old and deadly foe. Science (2000) 1.03
The genome project's conscience. Science (1996) 1.02
E-biomed morphs to E-biosci, focus shifts to reviewed papers. Science (1999) 1.00
NIH to produce a 'working draft' of the genome by 2001. Science (1998) 0.99
'Playing chicken' over gene markers. Science (1997) 0.99
Hand preference in a normal population. Cortex (1988) 0.99
New NIH rules promote greater sharing of tools and materials. Science (1999) 0.98
Senate Turns Up the Heat on NSF. Science (1993) 0.98
Phase II trial of tamoxifen and goserelin in recurrent epithelial ovarian cancer. Br J Cancer (2005) 0.98
Lobbyists seek to reslice NIH's pie. Science (1997) 0.98
Evidence of a monoaminergic-cholinergic imbalance related to visual hallucinations in Lewy body dementia. J Neurochem (1990) 0.97
Identification of factors that disrupt negative air pressurization of respiratory isolation rooms. Infect Control Hosp Epidemiol (2000) 0.96
Nuclear Winter Debate Heats Up: A study by the National Center for Atmospheric Research suggests most of the world would experience a mild nuclear winter, not a deep freeze. Science (1987) 0.96
Experimental solid tumour activity of N-[2-(dimethylamino)ethyl]-acridine-4-carboxamide. Cancer Chemother Pharmacol (1995) 0.95
Shutdown of research at Duke sends a message. Science (1999) 0.95
Drugs. Reinventing an ancient cure for malaria. Science (2000) 0.94
Psychological aspects of cytogenetic testing of uveal melanoma: preliminary findings and directions for future research. Eye (Lond) (2008) 0.93
Nerve cell loss in the thalamus in Alzheimer's disease and Parkinson's disease. Brain (1991) 0.93
A shadow falls on hepatitis B vaccination effort. Science (1998) 0.93
Epidemiology. Duke study faults overuse of stimulants for children. Science (2000) 0.92
The fluoride debate: one more time. Science (1990) 0.92
Genetic testing. Families sue hospital, scientist for control of Canavan gene. Science (2000) 0.91
Rehnquist's drug dependence poses dilemma. Science (1982) 0.91
The power of the front page of The New York Times. Science (1998) 0.90
Glucocorticoid receptor haploinsufficiency causes hypertension and attenuates hypothalamic-pituitary-adrenal axis and blood pressure adaptions to high-fat diet. FASEB J (2008) 0.90
Immune system theories on trial. Science (1986) 0.90
Rat genome spurs an unusual partnership. Science (2001) 0.90
The politics of breast cancer. Science (1993) 0.90
Selenium Poisons Refuge, California Politics: Drainage from the San Joaquin Valley has dumped selenium into a wildlife refuge and pitted two federal agencies against each other. Science (1985) 0.90
Gene therapy. Viral vectors still pack surprises. Science (2001) 0.89