R M Liskamp

Author PubWeight™ 28.16‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Different membrane anchoring positions of tryptophan and lysine in synthetic transmembrane alpha-helical peptides. J Biol Chem 1999 2.44
2 Sensitivity of single membrane-spanning alpha-helical peptides to hydrophobic mismatch with a lipid bilayer: effects on backbone structure, orientation, and extent of membrane incorporation. Biochemistry 2001 1.64
3 A myristoylated pseudosubstrate peptide, a novel protein kinase C inhibitor. J Biol Chem 1993 1.58
4 Inhibition of protein kinase C by tamoxifen. Cancer Res 1985 1.56
5 Specificity and function of the individual amino acids of an important determinant of human immunodeficiency virus type 1 that induces neutralizing activity. J Gen Virol 1989 1.41
6 Computer-assisted molecular modeling of tumor promoters: rationale for the activity of phorbol esters, teleocidin B, and aplysiatoxin. Proc Natl Acad Sci U S A 1986 1.05
7 Triphenylethylenes: a new class of protein kinase C inhibitors. J Natl Cancer Inst 1986 1.05
8 Wedgelike glycodendrimers as inhibitors of binding of mammalian galectins to glycoproteins, lactose maxiclusters, and cell surface glycoconjugates. Chembiochem 2001 1.02
9 Structure of glycosylated and unglycosylated gag and gag-pol precursor proteins of Moloney murine leukemia virus. J Virol 1983 1.00
10 Inhibition of neutrophil NADPH oxidase assembly by a myristoylated pseudosubstrate of protein kinase C. J Biol Chem 1993 0.99
11 Structure-activity relationships of sparsomycin and its analogues. Inhibition of peptide bond formation in cell-free systems and of L1210 and bacterial cell growth. J Med Chem 1987 0.87
12 Comparing mass spectrometric characteristics of peptides and peptoids. Rapid Commun Mass Spectrom 1996 0.85
13 Inhibition of protein kinase C and calmodulin by the geometric isomers cis- and trans-tamoxifen. Biopolymers 1990 0.85
14 Synthesis of a substrate of protein kinase C and its corresponding phosphopeptide. Int J Pept Protein Res 1989 0.82
15 Inhibition of IL-2 receptor induction and IL-2 production in the human leukemic cell line Jurkat by a novel peptide inhibitor of protein kinase C. Cell Immunol 1990 0.82
16 Cellular uptake and localization of fluorescent derivatives of phorbol ester tumor promoters. Biochem Biophys Res Commun 1985 0.82
17 Synthesis of cyclic peptides by ring-closing metathesis. J Org Chem 2000 0.81
18 Peptoid - peptide hybrids that bind Syk SH2 domains involved in signal transduction. Chembiochem 2001 0.80
19 Combinatorial chemistry of hydantoins. Bioorg Med Chem Lett 1998 0.80
20 TNF-mediated cytotoxicity of L929 cells: role of staurosporine in enhancement of cytotoxicity and translocation of protein kinase C isozymes. Cytokine 1997 0.80
21 A novel N-myristylated synthetic octapeptide inhibits protein kinase C activity and partially reverses murine fibrosarcoma cell resistance to adriamycin. Invest New Drugs 1991 0.79
22 Solid-phase synthesis of oligourea peptidomimetics employing the Fmoc protection strategy. J Org Chem 2001 0.78
23 A versatile method for the conjugation of proteins and peptides to poly[2-(dimethylamino)ethyl methacrylate]. Bioconjug Chem 1999 0.78
24 Molecular diversity of peptidomimetics: approaches to the solid-phase synthesis of peptidosulfonamides. Bioorg Med Chem 1996 0.78
25 Regulation of CD3 expression in a protein kinase C isozyme-deficient T-cell line. Immunology 1993 0.77
26 Increased stability of peptidesulfonamide peptidomimetics towards protease catalyzed degradation. Bioorg Med Chem 1999 0.76
27 N-myristyl-Lys-Arg-Thr-Leu-Arg: a novel protein kinase C inhibitor. Biochem Pharmacol 1990 0.76
28 A selectively deprotectable triazacyclophane scaffold for the construction of artificial receptors. Org Lett 2001 0.75
29 Structure-activity relationships of sparsomycin and its analogues. Octylsparsomycin: the first analogue more active than sparsomycin. J Med Chem 1984 0.75
30 Verification of the position of the phosphate group in some synthetic phosphopeptides by fast-atom bombardment and tandem mass spectrometry. Rapid Commun Mass Spectrom 1993 0.75
31 Computer-aided molecular modeling and design of DNA-inserting molecules. J Comput Aided Mol Des 1992 0.75
32 Determination of sparsomycin in plasma and urine of the dog by means of reversed-phase high-performance liquid chromatography and first pharmacokinetic results. J Chromatogr 1983 0.75
33 Sulfoxide configuration in sparsomycin determines time-dependent and competitive inhibition of peptidyl transferase. Biochem Biophys Res Commun 1984 0.75
34 Bio-inspired synthetic receptor molecules towards mimicry of vancomycin. Bioorg Med Chem Lett 2001 0.75
35 Peptides containing the sulfonamide transition-state isostere: synthesis and structure of N-acetyl-tauryl-L-proline methylamide. Int J Pept Protein Res 1995 0.75