Published in J Pharmacol Exp Ther on October 01, 1976
Effect of loperamide and naloxone on mouth-to-caecum transit time evaluated by lactulose hydrogen breath test. Gut (1985) 1.05
Antidiarrhoeal activity of loperamide: studies of its influence on ion transport across rabbit ileal mucosa in vitro. Gut (1982) 1.00
The action of loperamide in inhibiting prostaglandin-induced intestinal secretion in the rat. Br J Pharmacol (1981) 0.97
Naloxone inhibits the anti-diarrhoeal activity of loperamide. Br J Pharmacol (1979) 0.95
Initiation of motility in canine ileum by short chain fatty acids and inhibition by pharmacological agents. Gut (1988) 0.90
Effect of loperamide and naloxone on gastric acid secretion in healthy man. Gut (1981) 0.84
Unexpected prosecretory action component of loperamide at mu-opioid receptors in the guinea-pig colonic mucosa in vitro. Br J Pharmacol (1995) 0.75
Effects of a prostaglandin E1 derivative, SC-29333, and aspirin on gastric ionic fluxes and potential difference in dogs. J Pharmacol Exp Ther (1979) 1.08
32P analysis of DNA adducts in tissues of benzene-treated rats. Environ Health Perspect (1989) 1.05
Chemistry and synthetic development of misoprostol. Dig Dis Sci (1985) 1.05
SC-29333: a potent inhibitor of canin gastric secretion. Am J Dig Dis (1976) 1.04
Effects of E prostaglandins on canine gastric potential difference. Am J Dig Dis (1978) 1.03
The binding of [3H]diazepam to rat brain homogenates. J Pharmacol Exp Ther (1978) 0.93
Oxidation and phosphorylation in live mitochondria from alloxan and steptozotocin diabetic rats. Proc Soc Exp Biol Med (1971) 0.92
A method for in vitro culture of rat Zymbal gland: use in mechanistic studies of benzene carcinogenesis in combination with 32P-postlabeling. Environ Health Perspect (1989) 0.88
Evidence that hyperthermia produced by d-amphetamine is caused by a peripheral action of the drug. Life Sci (1969) 0.88
Effect of SC-29333, an inhibitor of gastric secretion, on canine gastric mucosal blood flow and serum gastrin levels. Arch Int Pharmacodyn Ther (1978) 0.87
The pharmacology of SC-27166: a novel antidiarrheal agent. J Pharmacol Exp Ther (1977) 0.87
Misoprostol in the treatment of duodenal ulcer. A multicenter double-blind placebo-controlled study. Dig Dis Sci (1985) 0.87
3,3-Diphenyl-3-(2-alkyl-1,3,4-oxadiazol-5-yl)propylcycloalkylamines, a novel series of antidiarrheal agents. J Med Chem (1976) 0.86
Comparative gastric antisecretory and antiulcer effects of prostaglandin E1 and its methyl ester in animals. Prostaglandins (1975) 0.86
Effect of sub-acute administration of clofibrate on the oxidation of fatty acids by liver mitochondria. Biochem Pharmacol (1977) 0.85
Interaction of loperamide with [3H]naloxone binding sites in guinea pig brain and myenteric plexus. Mol Pharmacol (1977) 0.85
Healing of benign gastric ulcer. A placebo-controlled comparison of two dosage regimens of misoprostol, a synthetic analog of prostaglandin E1. Dig Dis Sci (1985) 0.85
Inhibition of intestinal secretion in the dog: a new approach for the management of diarrheal states. J Pharmacol Exp Ther (1981) 0.85
Comparative cytoprotective effects against alcohol insult. Misoprostol versus cimetidine. Dig Dis Sci (1986) 0.84
An automated myeloperoxidase assay. Clin Chem (1990) 0.84
In vitro and in vivo percutaneous absorption of benzo[a]pyrene from petroleum crude-fortified soil in the rat. Bull Environ Contam Toxicol (1989) 0.84
Chronic systemic treatment with epidermal growth factor in pigs causes pronounced urothelial growth with accumulation of glycoconjugates. Am J Pathol (1995) 0.83
pH effects on oxidative phosphorylation of rat liver mitochondria. Am J Physiol (1972) 0.82
Systemic treatment with epidermal growth factor in pigs induces ductal proliferations in the pancreas. Gastroenterology (1997) 0.82
Idiopathic esophageal ulceration in acquired immunodeficiency syndrome: successful treatment with misoprostol and viscous lidocaine. Am J Gastroenterol (1998) 0.82
Dose-response, meal-stimulated gastric antisecretory study of prostaglandin E1 analog, misoprostol, in man. Dig Dis Sci (1988) 0.81
Effects of clofibrate, in vitro, on mitochondrial respiration and oxidative phosphorylation. Biochem Pharmacol (1973) 0.81
Health effects of the alkylbenzenes. I. Toluene. Toxicol Ind Health (1988) 0.81
Is peptic ulcer a prostaglandin deficiency disease? Hum Pathol (1986) 0.81
Effects of E prostaglandins, diphenoxylate and morphine on intestinal motility in vivo. Eur J Pharmacol (1975) 0.80
Lack of DNA adduct formation in mice treated with benzene. Mutat Res (1994) 0.80
SAR models for estimating the percutaneous absorption of polynuclear aromatic hydrocarbons. SAR QSAR Environ Res (1998) 0.80
Impedance planimetric characterization of the distal oesophagus in the Goettingen minipig. J Biomech (1996) 0.80
Health effects of the alkylbenzenes. II. Xylenes. Toxicol Ind Health (1989) 0.80
Correlation of mutagenic and dermal carcinogenic activities of mineral oils with polycyclic aromatic compound content. Fundam Appl Toxicol (1988) 0.80
Haloperidol binding to an opiate receptor site. Biochem Pharmacol (1975) 0.79
Misoprostol but not antacid prevents endotoxin-induced gastric mucosal injury: role of tumor necrosis factor-alpha. Dig Dis Sci (1991) 0.79
Percutaneous and oral absorption of chlorinated paraffins in the rat. Toxicol Ind Health (1987) 0.78
Gastrointestinal cytoprotective effects of misoprostol. Clinical efficacy overview. Dig Dis Sci (1985) 0.78
Biomechanical properties of the oesophagus damaged by endoscopic sclerotherapy. An impedance planimetric study in minipigs. Scand J Gastroenterol (1994) 0.78
Developmental toxicity of dermally applied crude oils in rats. J Toxicol Environ Health (1997) 0.78
Tissue distribution of 131I-labelled epidermal growth factor in the pig visualized by dynamic scintigraphy. J Endocrinol (1995) 0.78
Systemic treatment with recombinant human epidermal growth factor accelerates healing of sclerotherapy-induced esophageal ulcers and prevents esophageal stricture formations in pigs. Dig Dis Sci (1994) 0.78
Further studies concerning the effects of clofibrate on respiration and oxidative phosphorylation of rat liver mitochondria. Biochem Pharmacol (1974) 0.78
Percutaneous absorption of benzo[a]pyrene in the rat: comparison of in vivo and in vitro results. Toxicol Ind Health (1986) 0.78
Percutaneous absorption of anthracene in the rat: comparison of in vivo and in vitro results. Toxicol Ind Health (1986) 0.78
Effect of misoprostol, an antiulcer prostaglandin, on serum gastrin in patients with duodenal ulcer. Dig Dis Sci (1986) 0.77
Antiestrogenicity of clarified slurry oil and two crude oils in a human breast-cancer cell assay. J Toxicol Environ Health A (2001) 0.77
Gastric antisecretory actions of (15S)-15-methyl prostaglandin E2 methyl ester and natural prostaglandin E2 in rhesus monkeys. Prostaglandins (1976) 0.77
Gastrointestinal toxicity of over-the-counter analgesics. Am J Gastroenterol (1998) 0.77
DNA adduction by phenol, hydroquinone, or benzoquinone in vitro but not in vivo: nuclease P1-enhanced 32P-postlabeling of adducts as labeled nucleoside bisphosphates, dinucleotides and nucleoside monophosphates. Carcinogenesis (1990) 0.77
The subcellular localization of a cardioexcitatory peptide in the pericardial organs of the crab, Cancer borealis. Gen Comp Endocrinol (1970) 0.77
Chronic systemic treatment with epidermal growth factor induces hypergastrinaemia in Goettingen minipigs. Scand J Gastroenterol (1995) 0.77
Refractory peptic ulcers. J Assoc Acad Minor Phys (1992) 0.77
Misoprostol prevents damage to the gastric mucosa by stabilizing the mast cells. Prostaglandins (1987) 0.77
Chronic treatment with epidermal growth factor causes esophageal epithelial hyperplasia in pigs and rats. Dig Dis Sci (1995) 0.76
Cytoprotection by a synthetic prostaglandin against ethanol-induced gastric mucosal damage. A double-blind endoscopic study in human subjects. Gastrointest Endosc (1986) 0.76
Current status of benzene teratology: a brief review. J Environ Pathol Toxicol (1980) 0.76
Epidermal growth factor attenuates the sclerotherapy-induced biomechanical properties of the oesophagus. An experimental study in minipigs. Scand J Gastroenterol (1995) 0.76
Effect of diethylaminoethyl diphenylpropyl-acetate hydrochloride (SKF-525A) on the norepinephrine-depleting actions of d-amphetamine. Biochem Pharmacol (1971) 0.76
Use of a surrogate aerosol in a preliminary screening for the potential carcinogenicity of coal coated with No. 6 fuel oil. Am Ind Hyg Assoc J (1998) 0.76
Antidiarrheal and central nervous system activities of SC-27166 (2-[3 - 5 - methyl - 1, 3, 4 - oxadiazol - 2 - yl) - 3, 3 - diphenylpropyl] - 2 - azabicyclo [2.2.2]octane), a new antidiarrheal agent, resulting from binding to opiate receptor sites of brain and myenteric plexus. J Pharmacol Exp Ther (1977) 0.76
Benzene induces a dose-responsive increase in the frequency of micronucleated cells in rat Zymbal glands. Environ Health Perspect (1996) 0.76
Pharmacokinetics and metabolism of benzene in Zymbal gland and other key target tissues after oral administration in rats. Environ Health Perspect (1989) 0.76
Overview of clinical safety with misoprostol. Dig Dis Sci (1985) 0.75
Synthesis and gastric antisecretory properties of 15-deoxy-16-hydroxyprostaglandin E analogues. J Med Chem (1977) 0.75
Prostaglandins, NSAIDS, and GI mucosal integrity: can we identify patients at risk of NSAID-induced gastric injury? Am J Gastroenterol (1996) 0.75
Omega-3 fatty acids and bowel cancer. Gastroenterology (1993) 0.75
Misoprostol attenuates aspirin-induced changes in potential difference and associated damage in canine gastric mucosa. Clin Invest Med (1987) 0.75
The binding of strychnine and strychnine analogs to synaptic membranes of rat brainstem and spinal cord. J Pharmacol Exp Ther (1977) 0.75
Gastric antisecretory effects of propantheline bromide and metiamide in rhesus monkeys. Arch Int Pharmacodyn Ther (1978) 0.75
Effects of cations and anions on the binding of 3H-diazepam to rat brain. Proc Soc Exp Biol Med (1978) 0.75
Systemic toxicity from subchronic dermal exposure, chemical characterization, and dermal penetration of catalytically cracked clarified slurry oil. Toxicol Ind Health (1986) 0.75
Correlation of systemic and developmental toxicities with chemical component classes of refinery streams. Fundam Appl Toxicol (1994) 0.75
Estimation of the dermal carcinogenic activity of petroleum fractions using a modified Ames assay. Cell Biol Toxicol (1984) 0.75
Effect of clofibrate administration on several biochemical parameters of normal and thyroidectomized rats. Biochem Pharmacol (1977) 0.75
Assessment of diabetogenic drug activity in the rat: 5,5-diphenyl-2-thiohydantoin. J Toxicol Environ Health (1977) 0.75
Gastric antisecretory effects of E prostaglandins in Rhesus monkeys. Am J Dig Dis (1976) 0.75
Predicting carcinogenicity of petroleum distillation fractions using a modified Salmonella mutagenicity assay. Cell Biol Toxicol (1986) 0.75
Gastric antiulcer and antisecretory effects of carbenoxolone, aldosterone and desoxycorticosterone in rats. Arch Int Pharmacodyn Ther (1979) 0.75
Safety evaluation of petroleum products using an in vitro eye irritation test battery. Toxicol In Vitro (1994) 0.75
Synergistic actions of propantheline bromide with cimetidine and thiopropazate hydrochloride in the prevention of stress ulcer formation in rats. J Pharmacol Exp Ther (1979) 0.75
Synthesis and biological evaluation of omega-homologues of prostaglandin E1. J Med Chem (1976) 0.75
Enhancement of renal gluconeogenesis by clofibrate. Biochem Pharmacol (1978) 0.75
Metabolism cage for carbon dioxide trapping studies. J Toxicol Environ Health (1977) 0.75
Percutaneous absorption of anthracene in the rat: comparison of in vivo and in vitro results. Toxicol Ind Health (1986) 0.75
Renal gluconeogenesis in clofibrate-treated rats. J Pharmacol Exp Ther (1978) 0.75
Naloxone reversal of drug-induced diarrhea in mice. Arch Int Pharmacodyn Ther (1979) 0.75
Assessment of diabetogenic drug activity in the rat: diphenylhydantoin. J Toxicol Environ Health (1976) 0.75
Influence of the position of the side chain hydroxy group on the gastric antisecretory and antiulcer actions of E1 prostaglandin analogs. Prostaglandins (1975) 0.75
Ion-pair reverse phase liquid chromatographic determination of sodium acifluorfen in feed. J Assoc Off Anal Chem (1983) 0.75
Effects of 7-oxa-13-prostynoic acid (7-OPyA) and prostaglandin E1 methyl ester on canine gastric secretion. Prostaglandins (1977) 0.75
Evaluation of the EYTEX system as a screen for eye irritancy of petroleum products. Toxicol In Vitro (1994) 0.75
Synthesis of beta-spiro[pyrrolidinoindolines], their binding to the glycine receptor, and in vivo biological acitivity. J Med Chem (1977) 0.75
Effect of oral and intravenous propantheline bromide on pentagastrin-stimulated canine gastric secretion. Arch Int Pharmacodyn Ther (1978) 0.75
Canine gastrointestinal motility effects of prostaglandin F2 alpha in vivo. Arch Int Pharmacodyn Ther (1979) 0.75
Synthesis and gastric antisecretory properties of 4,5-unsaturated derivatives of 15-deoxy-16-hydroxy-16-methylprostaglandin E1. J Med Chem (1983) 0.75